CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
ORF3a | 253 | S253P | nonsyn | Tcc | Ccc | 115088 | 114966 | 0.99894 | 26149-26151 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
ORF3a | 253 | S253P | Tcc | Ccc | 114966 | 115088 | All | 0.021989 |
ORF3a | 253 | S253P | Tcc | Ccc | 62673 | 62765 | P.1 | 0.98735 |
ORF3a | 253 | S253P | Tcc | Ccc | 20871 | 20883 | P.1.14 | 0.997658 |
ORF3a | 253 | S253P | Tcc | Ccc | 6107 | 6107 | P.1.17 | 0.987868 |
ORF3a | 253 | S253P | Tcc | Ccc | 4230 | 4235 | P.1.15 | 0.982807 |
ORF3a | 253 | S253P | Tcc | Ccc | 3659 | 3659 | P.1.10 | 0.985988 |
ORF3a | 253 | S253P | Tcc | Ccc | 3112 | 3112 | P.1.7 | 0.993614 |
ORF3a | 253 | S253P | Tcc | Ccc | 2868 | 2876 | P.1.1 | 0.911055 |
ORF3a | 253 | S253P | Tcc | Ccc | 2632 | 2632 | P.1.16 | 0.984661 |
ORF3a | 253 | S253P | Tcc | Ccc | 1889 | 1890 | P.1.12 | 0.914327 |
ORF3a | 253 | S253P | Tcc | Ccc | 1141 | 1141 | P.1.17.1 | 0.99825 |
ORF3a | 253 | S253P | Tcc | Ccc | 1098 | 1098 | P.1.13 | 0.986523 |
ORF3a | 253 | S253P | Tcc | Ccc | 1023 | 1023 | P.1.4 | 0.999023 |
ORF3a | 253 | S253P | Tcc | Ccc | 861 | 861 | P.1.2 | 0.995376 |
ORF3a | 253 | S253P | Tcc | Ccc | 508 | 508 | P.1.6 | 0.988327 |
ORF3a | 253 | S253P | Tcc | Ccc | 312 | 314 | B.1.1.28 | 0.097106 |
ORF3a | 253 | S253P | Tcc | Ccc | 209 | 209 | B.1.427 | 0.010554 |
ORF3a | 253 | S253P | Tcc | Ccc | 209 | 209 | P.1.8 | 1 |
ORF3a | 253 | S253P | Tcc | Ccc | 206 | 206 | P.1.9 | 0.990385 |
ORF3a | 253 | S253P | Tcc | Ccc | 168 | 169 | B.1 | 0.001539 |
ORF3a | 253 | S253P | Tcc | Ccc | 153 | 153 | B.1.1 | 0.002776 |
ORF3a | 253 | S253P | Tcc | Ccc | 108 | 108 | P.1.10.1 | 0.878049 |
ORF3a | 253 | S253P | Tcc | Ccc | 103 | 103 | B.1.1.7 | 0.000092 |
ORF3a | 253 | S253P | Tcc | Ccc | 98 | 98 | P.1.11 | 1 |
ORF3a | 253 | S253P | Tcc | Ccc | 69 | 69 | AY.4 | 0.000107 |
ORF3a | 253 | S253P | Tcc | Ccc | 58 | 58 | AY.25 | 0.000349 |
ORF3a | 253 | S253P | Tcc | Ccc | 40 | 41 | AY.44 | 0.000243 |
ORF3a | 253 | S253P | Tcc | Ccc | 34 | 34 | AY.93 | 0.009285 |
ORF3a | 253 | S253P | Tcc | Ccc | 32 | 32 | AY.3 | 0.000318 |
ORF3a | 253 | S253P | Tcc | Ccc | 29 | 29 | B.1.1.528 | 0.139423 |
ORF3a | 253 | S253P | Tcc | Ccc | 29 | 29 | P.1.3 | 1 |
ORF3a | 253 | S253P | Tcc | Ccc | 28 | 28 | B.1.617.2 | 0.000105 |
ORF3a | 253 | S253P | Tcc | Ccc | 24 | 24 | P.1.10.2 | 1 |
ORF3a | 253 | S253P | Tcc | Ccc | 22 | 22 | B.1.2 | 0.000194 |
ORF3a | 253 | S253P | Tcc | Ccc | 21 | 21 | B.1.36.21 | 0.045356 |
ORF3a | 253 | S253P | Tcc | Ccc | 19 | 19 | C.37 | 0.002205 |
ORF3a | 253 | S253P | Tcc | Ccc | 18 | 18 | A.2.5 | 0.008982 |
ORF3a | 253 | S253P | Tcc | Ccc | 14 | 14 | B.1.177 | 0.000184 |
ORF3a | 253 | S253P | Tcc | Ccc | 13 | 13 | AY.103 | 0.000081 |
ORF3a | 253 | S253P | Tcc | Ccc | 13 | 13 | AY.26 | 0.000368 |
ORF3a | 253 | S253P | Tcc | Ccc | 13 | 13 | AY.43 | 0.000058 |
ORF3a | 253 | S253P | Tcc | Ccc | 13 | 13 | P.1.5 | 1 |
ORF3a | 253 | S253P | Tcc | Ccc | 10 | 10 | AY.6 | 0.000411 |
ORF3a | 253 | S253P | Tcc | Ccc | 10 | 10 | AY.9.2 | 0.000367 |
ORF3a | 253 | S253P | Tcc | Ccc | 10 | 10 | P.2 | 0.001866 |
ORF3a | 253 | S253P | Tcc | Ccc | 8 | 8 | B.1.1.161 | 0.028269 |
ORF3a | 253 | S253P | Tcc | Ccc | 8 | 8 | B.1.221 | 0.000568 |
ORF3a | 253 | S253P | Tcc | Ccc | 8 | 8 | B.1.349 | 0.005718 |
ORF3a | 253 | S253P | Tcc | Ccc | 8 | 8 | B.1.429 | 0.000188 |
ORF3a | 253 | S253P | Tcc | Ccc | 8 | 8 | B.1.621 | 0.000708 |
ORF3a | 253 | S253P | Tcc | Ccc | 7 | 7 | AY.20 | 0.000272 |
ORF3a | 253 | S253P | Tcc | Ccc | 7 | 7 | B.1.526 | 0.000165 |
ORF3a | 253 | S253P | Tcc | Ccc | 6 | 6 | B.1.234 | 0.000792 |
ORF3a | 253 | S253P | Tcc | Ccc | 6 | 6 | B.1.258.3 | 0.01005 |
ORF3a | 253 | S253P | Tcc | Ccc | 6 | 6 | B.1.637 | 0.000438 |
ORF3a | 253 | S253P | Tcc | Ccc | 5 | 5 | B.1.1.507 | 0.043478 |
ORF3a | 253 | S253P | Tcc | Ccc | 4 | 4 | AY.27 | 0.000259 |
ORF3a | 253 | S253P | Tcc | Ccc | 4 | 4 | AY.4.2 | 0.000087 |
ORF3a | 253 | S253P | Tcc | Ccc | 4 | 4 | AY.5 | 0.000083 |
ORF3a | 253 | S253P | Tcc | Ccc | 3 | 3 | AY.13 | 0.000483 |
ORF3a | 253 | S253P | Tcc | Ccc | 3 | 3 | AY.41 | 0.000882 |
ORF3a | 253 | S253P | Tcc | Ccc | 3 | 3 | B.1.1.372 | 0.002066 |
ORF3a | 253 | S253P | Tcc | Ccc | 3 | 3 | B.1.1.409 | 0.008499 |
ORF3a | 253 | S253P | Tcc | Ccc | 3 | 3 | B.1.596 | 0.000261 |
ORF3a | 253 | S253P | Tcc | Ccc | 3 | 3 | B.1.623 | 0.001609 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | AY.14 | 0.000176 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | AY.42 | 0.00008 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | AY.5.4 | 0.000553 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | AY.61 | 0.00021 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | AY.74 | 0.000231 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | AY.75.1 | 0.000361 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | AY.98.1 | 0.000097 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | B | 0.000256 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | B.1.1.220 | 0.003717 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | B.1.1.312 | 0.003824 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | B.1.1.519 | 0.000079 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | B.1.160 | 0.000062 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | B.1.177.7 | 0.00033 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | B.1.258 | 0.000133 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | B.1.258.6 | 0.039216 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | B.1.311 | 0.000549 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | B.1.351.5 | 0.001199 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | B.1.533 | 0.019231 |
ORF3a | 253 | S253P | Tcc | Ccc | 2 | 2 | C.37.1 | 0.005236 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.101 | 0.00049 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.102 | 0.000027 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.115 | 0.005208 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.116 | 0.000287 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.117 | 0.000085 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.119 | 0.000035 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.120 | 0.000037 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.120.1 | 0.000321 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.23.1 | 0.000417 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.28 | 0.00189 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.29 | 0.000016 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.3.1 | 0.000085 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.32 | 0.000532 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.36 | 0.000148 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.38 | 0.000499 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.39.1 | 0.00004 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.46 | 0.000104 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.47 | 0.000031 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.5.3 | 0.000337 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.62 | 0.000436 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.68 | 0.000274 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.83 | 0.001724 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.9.1 | 0.000084 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | AY.99 | 0.001049 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.1.121 | 0.002427 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.1.198 | 0.001468 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.1.236 | 0.006897 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.1.265 | 0.003155 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.1.269 | 0.001353 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.1.285 | 0.006536 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.1.33 | 0.000421 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.1.37 | 0.000193 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.1.397 | 0.002252 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.1.407 | 0.041667 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.1.432 | 0.001266 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.1.54 | 0.003021 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.1.8 | 0.003584 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.170 | 0.00431 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.177.17 | 0.000821 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.177.23 | 0.003236 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.179 | 0.003759 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.206 | 0.000816 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.214 | 0.003663 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.214.2 | 0.0006 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.243 | 0.00007 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.258.11 | 0.000396 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.369 | 0.000285 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.375 | 0.00082 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.400 | 0.000429 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.415 | 0.014286 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.497 | 0.000315 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.525 | 0.000113 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.561 | 0.000397 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.575 | 0.000303 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.588 | 0.00091 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.617.1 | 0.000129 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.636 | 0.006711 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.9.4 | 0.006135 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.1.91 | 0.002075 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | B.4.5 | 0.011905 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | C.23 | 0.005814 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | C.35 | 0.000774 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | P.4 | 0.003802 |
ORF3a | 253 | S253P | Tcc | Ccc | 1 | 1 | P.7 | 0.004367 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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