CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF3a : CodonNum = 174 & Codon = gTc

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF3a	174	G174V		nonsyn	gGc	gTc	2864	2863	0.999651	25912-25914

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF3a	174	G174V	gGc	gTc	2863	2864	All	0.000548
ORF3a	174	G174V	gGc	gTc	1161	1161	AY.25	0.006983
ORF3a	174	G174V	gGc	gTc	664	664	B.1	0.006082
ORF3a	174	G174V	gGc	gTc	220	220	B.1.1.222	0.04488
ORF3a	174	G174V	gGc	gTc	202	202	B.1.1.39	0.102956
ORF3a	174	G174V	gGc	gTc	171	171	B.1.36	0.024949
ORF3a	174	G174V	gGc	gTc	122	122	B.1.1.7	0.000109
ORF3a	174	G174V	gGc	gTc	45	45	B.1.1	0.000816
ORF3a	174	G174V	gGc	gTc	26	27	B.1.617.2	0.000098
ORF3a	174	G174V	gGc	gTc	21	21	A.23.1	0.014789
ORF3a	174	G174V	gGc	gTc	18	18	AY.4	0.000028
ORF3a	174	G174V	gGc	gTc	15	15	AY.44	0.000091
ORF3a	174	G174V	gGc	gTc	9	9	B.1.425	0.026946
ORF3a	174	G174V	gGc	gTc	8	8	AY.102	0.000212
ORF3a	174	G174V	gGc	gTc	8	8	AY.103	0.00005
ORF3a	174	G174V	gGc	gTc	8	8	B.1.336	0.019512
ORF3a	174	G174V	gGc	gTc	7	7	AY.30	0.00277
ORF3a	174	G174V	gGc	gTc	7	7	AY.39	0.000173
ORF3a	174	G174V	gGc	gTc	7	7	B.1.1.1	0.002287
ORF3a	174	G174V	gGc	gTc	7	7	B.1.456	0.022876
ORF3a	174	G174V	gGc	gTc	6	6	B.1.177	0.000079
ORF3a	174	G174V	gGc	gTc	6	6	B.1.36.22	0.007246
ORF3a	174	G174V	gGc	gTc	6	6	B.1.441	0.057692
ORF3a	174	G174V	gGc	gTc	5	5	B.1.210	0.010661
ORF3a	174	G174V	gGc	gTc	4	4	AY.43	0.000018
ORF3a	174	G174V	gGc	gTc	4	4	B.1.1.46	0.017467
ORF3a	174	G174V	gGc	gTc	4	4	B.1.433	0.01278
ORF3a	174	G174V	gGc	gTc	4	4	C.35	0.003096
ORF3a	174	G174V	gGc	gTc	4	4	C.37	0.000464
ORF3a	174	G174V	gGc	gTc	3	3	AY.32	0.001597
ORF3a	174	G174V	gGc	gTc	3	3	AY.58	0.002722
ORF3a	174	G174V	gGc	gTc	3	3	AY.72	0.004082
ORF3a	174	G174V	gGc	gTc	3	3	B.1.1.207	0.003546
ORF3a	174	G174V	gGc	gTc	3	3	B.1.1.397	0.006757
ORF3a	174	G174V	gGc	gTc	3	3	B.1.111	0.003525
ORF3a	174	G174V	gGc	gTc	3	3	B.1.160	0.000094
ORF3a	174	G174V	gGc	gTc	3	3	C.16	0.003181
ORF3a	174	G174V	gGc	gTc	2	2	AY.120.2.1	0.000997
ORF3a	174	G174V	gGc	gTc	2	2	AY.5.4	0.000553
ORF3a	174	G174V	gGc	gTc	2	2	B.1.1.306	0.000877
ORF3a	174	G174V	gGc	gTc	2	2	B.1.1.50	0.001358
ORF3a	174	G174V	gGc	gTc	2	2	B.1.1.70	0.000682
ORF3a	174	G174V	gGc	gTc	2	2	B.1.143	0.042553
ORF3a	174	G174V	gGc	gTc	2	2	B.1.160.32	0.008584
ORF3a	174	G174V	gGc	gTc	2	2	B.1.298	0.004228
ORF3a	174	G174V	gGc	gTc	2	2	B.1.36.8	0.002
ORF3a	174	G174V	gGc	gTc	2	2	B.1.388	0.181818
ORF3a	174	G174V	gGc	gTc	2	2	B.1.429	0.000047
ORF3a	174	G174V	gGc	gTc	1	1	A.2	0.000662
ORF3a	174	G174V	gGc	gTc	1	1	A.2.5.2	0.001572
ORF3a	174	G174V	gGc	gTc	1	1	AY.105	0.000643
ORF3a	174	G174V	gGc	gTc	1	1	AY.117	0.000085
ORF3a	174	G174V	gGc	gTc	1	1	AY.118	0.000063
ORF3a	174	G174V	gGc	gTc	1	1	AY.119	0.000035
ORF3a	174	G174V	gGc	gTc	1	1	AY.33	0.000067
ORF3a	174	G174V	gGc	gTc	1	1	AY.4.2	0.000022
ORF3a	174	G174V	gGc	gTc	1	1	AY.45	0.000122
ORF3a	174	G174V	gGc	gTc	1	1	AY.46	0.000104
ORF3a	174	G174V	gGc	gTc	1	1	AY.6	0.000041
ORF3a	174	G174V	gGc	gTc	1	1	AY.68	0.000274
ORF3a	174	G174V	gGc	gTc	1	1	AY.75	0.000056
ORF3a	174	G174V	gGc	gTc	1	1	AY.9.2	0.000037
ORF3a	174	G174V	gGc	gTc	1	1	AY.90	0.000684
ORF3a	174	G174V	gGc	gTc	1	1	AY.98.1	0.000048
ORF3a	174	G174V	gGc	gTc	1	1	B	0.000128
ORF3a	174	G174V	gGc	gTc	1	1	B.1.1.214	0.000055
ORF3a	174	G174V	gGc	gTc	1	1	B.1.1.311	0.000358
ORF3a	174	G174V	gGc	gTc	1	1	B.1.1.322	0.008772
ORF3a	174	G174V	gGc	gTc	1	1	B.1.1.372	0.000689
ORF3a	174	G174V	gGc	gTc	1	1	B.1.1.500	0.02
ORF3a	174	G174V	gGc	gTc	1	1	B.1.1.519	0.00004
ORF3a	174	G174V	gGc	gTc	1	1	B.1.128	0.000635
ORF3a	174	G174V	gGc	gTc	1	1	B.1.2	0.000009
ORF3a	174	G174V	gGc	gTc	1	1	B.1.236	0.002053
ORF3a	174	G174V	gGc	gTc	1	1	B.1.243	0.00007
ORF3a	174	G174V	gGc	gTc	1	1	B.1.258	0.000067
ORF3a	174	G174V	gGc	gTc	1	1	B.1.349	0.000715
ORF3a	174	G174V	gGc	gTc	1	1	B.1.36.10	0.004785
ORF3a	174	G174V	gGc	gTc	1	1	B.1.36.17	0.000494
ORF3a	174	G174V	gGc	gTc	1	1	B.1.399	0.001934
ORF3a	174	G174V	gGc	gTc	1	1	B.1.411	0.003704
ORF3a	174	G174V	gGc	gTc	1	1	B.1.417	0.028571
ORF3a	174	G174V	gGc	gTc	1	1	B.1.442	0.035714
ORF3a	174	G174V	gGc	gTc	1	1	B.1.443	0.004673
ORF3a	174	G174V	gGc	gTc	1	1	B.1.459	0.004082
ORF3a	174	G174V	gGc	gTc	1	1	B.1.466.2	0.000391
ORF3a	174	G174V	gGc	gTc	1	1	B.1.468	0.005714
ORF3a	174	G174V	gGc	gTc	1	1	B.1.564.1	0.001577
ORF3a	174	G174V	gGc	gTc	1	1	B.1.596	0.000087
ORF3a	174	G174V	gGc	gTc	1	1	B.1.8	0.001972
ORF3a	174	G174V	gGc	gTc	1	1	B.1.81	0.021277
ORF3a	174	G174V	gGc	gTc	1	1	B.40	0.000364
ORF3a	174	G174V	gGc	gTc	1	1	B.6	0.00091
ORF3a	174	G174V	gGc	gTc	1	1	C.22	0.071429
ORF3a	174	G174V	gGc	gTc	1	1	C.36	0.000911
ORF3a	174	G174V	gGc	gTc	1	1	P.1	0.000016

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.