CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp9 : Mut = L45L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp945L45LL4185LsynttAttG415440700.97977912818-12820
ORF1ab/nsp945L45LL4185LsynTtaCta4154840.020221512818-12820

Details of the mutation L45L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp945L45LttAttG40704154All0.000778
ORF1ab/nsp945L45LTtaCta844154All0.000016
ORF1ab/nsp945L45LttAttG721721B.1.3460.944954
ORF1ab/nsp945L45LttAttG543544AY.1020.014397
ORF1ab/nsp945L45LTtaCta1544AY.1020.000027
ORF1ab/nsp945L45LttAttG479489B.1.1.70.000429
ORF1ab/nsp945L45LTtaCta10489B.1.1.70.000009
ORF1ab/nsp945L45LttAttG274313AY.40.000426
ORF1ab/nsp945L45LTtaCta39313AY.40.000061
ORF1ab/nsp945L45LttAttG202206B.1.617.20.000761
ORF1ab/nsp945L45LTtaCta4206B.1.617.20.000015
ORF1ab/nsp945L45LttAttG125125P.10.001969
ORF1ab/nsp945L45LttAttG111112B.1.20.000977
ORF1ab/nsp945L45LTtaCta1112B.1.20.000009
ORF1ab/nsp945L45LttAttG106106A.191
ORF1ab/nsp945L45LttAttG101103P.1.140.004828
ORF1ab/nsp945L45LTtaCta2103P.1.140.000096
ORF1ab/nsp945L45LttAttG9494B.1.6210.008321
ORF1ab/nsp945L45LttAttG8383AY.3.10.007076
ORF1ab/nsp945L45LttAttG6768B.10.000614
ORF1ab/nsp945L45LTtaCta168B.10.000009
ORF1ab/nsp945L45LttAttG6767AY.250.000403
ORF1ab/nsp945L45LttAttG6767AY.440.000408
ORF1ab/nsp945L45LttAttG5252AY.1030.000323
ORF1ab/nsp945L45LttAttG3636AY.430.000159
ORF1ab/nsp945L45LttAttG3535C.400.972222
ORF1ab/nsp945L45LttAttG3333AY.1170.002789
ORF1ab/nsp945L45LttAttG3030AY.1200.001115
ORF1ab/nsp945L45LttAttG2929AY.1000.001334
ORF1ab/nsp945L45LttAttG2828AY.9.20.001028
ORF1ab/nsp945L45LttAttG2727B.1.6090.012943
ORF1ab/nsp945L45LttAttG2626AY.470.000809
ORF1ab/nsp945L45LttAttG2122AY.30.000209
ORF1ab/nsp945L45LTtaCta122AY.30.00001
ORF1ab/nsp945L45LttAttG2222B.1.10.000399
ORF1ab/nsp945L45LttAttG2121B.1.1.10.006861
ORF1ab/nsp945L45LttAttG2020B.1.5960.001743
ORF1ab/nsp945L45LttAttG1819B.1.2430.001253
ORF1ab/nsp945L45LTtaCta119B.1.2430.00007
ORF1ab/nsp945L45LttAttG1618B.1.1770.000211
ORF1ab/nsp945L45LTtaCta218B.1.1770.000026
ORF1ab/nsp945L45LttAttG1717AY.390.00042
ORF1ab/nsp945L45LttAttG1717B.1.1.460.074236
ORF1ab/nsp945L45LttAttG1717B.1.5870.032258
ORF1ab/nsp945L45LttAttG1416AY.230.000976
ORF1ab/nsp945L45LTtaCta216AY.230.000139
ORF1ab/nsp945L45LttAttG1616B.1.1600.000499
ORF1ab/nsp945L45LttAttG1516B.1.5260.000353
ORF1ab/nsp945L45LTtaCta116B.1.5260.000024
ORF1ab/nsp945L45LttAttG1515AY.1190.00053
ORF1ab/nsp945L45LttAttG1515AY.750.00084
ORF1ab/nsp945L45LttAttG1313B.1.2580.000865
ORF1ab/nsp945L45LttAttG1212C.370.001393
ORF1ab/nsp945L45LttAttG1111B.1.5950.002871
ORF1ab/nsp945L45LttAttG1010B.1.258.170.00104
ORF1ab/nsp945L45LttAttG1010B.1.4270.000505
ORF1ab/nsp945L45LttAttG1010B.1.4710.027322
ORF1ab/nsp945L45LttAttG99AY.60.00037
ORF1ab/nsp945L45LttAttG99AY.9.10.000754
ORF1ab/nsp945L45LttAttG99AY.900.00616
ORF1ab/nsp945L45LttAttG99B.1.1.5190.000357
ORF1ab/nsp945L45LttAttG99B.1.160.260.021792
ORF1ab/nsp945L45LttAttG88AY.290.000126
ORF1ab/nsp945L45LttAttG78AY.330.000467
ORF1ab/nsp945L45LTtaCta18AY.330.000067
ORF1ab/nsp945L45LttAttG78B.1.3510.000208
ORF1ab/nsp945L45LTtaCta18B.1.3510.00003
ORF1ab/nsp945L45LttAttG77AY.1180.000439
ORF1ab/nsp945L45LttAttG47AY.200.000155
ORF1ab/nsp945L45LTtaCta37AY.200.000117
ORF1ab/nsp945L45LttAttG77AY.610.000733
ORF1ab/nsp945L45LttAttG77AY.930.001912
ORF1ab/nsp945L45LttAttG77B0.000895
ORF1ab/nsp945L45LttAttG77B.1.2210.000497
ORF1ab/nsp945L45LttAttG66AY.360.000889
ORF1ab/nsp945L45LttAttG66AY.50.000124
ORF1ab/nsp945L45LttAttG66B.1.1.2140.000333
ORF1ab/nsp945L45LttAttG66B.1.1.2440.092308
ORF1ab/nsp945L45LttAttG66B.1.1.280.001867
ORF1ab/nsp945L45LttAttG66B.1.360.000875
ORF1ab/nsp945L45LttAttG56B.1.5250.000566
ORF1ab/nsp945L45LTtaCta16B.1.5250.000113
ORF1ab/nsp945L45LttAttG66B.1.5820.002944
ORF1ab/nsp945L45LttAttG66B.1.780.051282
ORF1ab/nsp945L45LttAttG66R.10.00054
ORF1ab/nsp945L45LttAttG55AY.1070.00233
ORF1ab/nsp945L45LttAttG55AY.260.000142
ORF1ab/nsp945L45LttAttG55AY.4.50.000537
ORF1ab/nsp945L45LttAttG55AY.460.00052
ORF1ab/nsp945L45LttAttG55AY.540.000477
ORF1ab/nsp945L45LttAttG55AY.850.002136
ORF1ab/nsp945L45LTtaCta55B.1.1.2580.016287
ORF1ab/nsp945L45LttAttG55B.1.177.810.000947
ORF1ab/nsp945L45LttAttG55B.1.466.20.001956
ORF1ab/nsp945L45LttAttG44AY.340.000388
ORF1ab/nsp945L45LttAttG44AY.39.10.000158
ORF1ab/nsp945L45LttAttG44AY.560.006421
ORF1ab/nsp945L45LttAttG44AY.98.10.000194
ORF1ab/nsp945L45LttAttG44B.1.1.2220.000816
ORF1ab/nsp945L45LttAttG44B.1.1.3060.001754
ORF1ab/nsp945L45LttAttG44B.1.177.460.003673
ORF1ab/nsp945L45LttAttG44B.1.221.10.011628
ORF1ab/nsp945L45LttAttG44B.1.258.140.003922
ORF1ab/nsp945L45LttAttG44B.1.4290.000094
ORF1ab/nsp945L45LttAttG44B.1.5640.001704
ORF1ab/nsp945L45LttAttG44B.1.5680.004444
ORF1ab/nsp945L45LttAttG44C.36.30.002269
ORF1ab/nsp945L45LttAttG44P.1.20.004624
ORF1ab/nsp945L45LttAttG33AY.1130.000427
ORF1ab/nsp945L45LttAttG33AY.116.10.000934
ORF1ab/nsp945L45LttAttG33AY.240.001293
ORF1ab/nsp945L45LttAttG33AY.270.000194
ORF1ab/nsp945L45LttAttG33AY.350.000699
ORF1ab/nsp945L45LttAttG33AY.4.20.000065
ORF1ab/nsp945L45LttAttG33B.1.1.330.001263
ORF1ab/nsp945L45LttAttG33B.1.1.630.001157
ORF1ab/nsp945L45LttAttG33B.1.1810.058824
ORF1ab/nsp945L45LttAttG33B.1.214.20.001799
ORF1ab/nsp945L45LttAttG33B.1.6370.000219
ORF1ab/nsp945L45LttAttG33P.1.120.001452
ORF1ab/nsp945L45LTtaCta22AY.1060.00067
ORF1ab/nsp945L45LttAttG22AY.130.000322
ORF1ab/nsp945L45LttAttG22AY.320.001065
ORF1ab/nsp945L45LttAttG22AY.450.000243
ORF1ab/nsp945L45LttAttG22AY.5.40.000553
ORF1ab/nsp945L45LttAttG22AY.550.001835
ORF1ab/nsp945L45LttAttG22AY.680.000547
ORF1ab/nsp945L45LttAttG22AY.690.000373
ORF1ab/nsp945L45LttAttG22AY.75.10.000361
ORF1ab/nsp945L45LttAttG22AY.80.001212
ORF1ab/nsp945L45LttAttG22AY.890.009804
ORF1ab/nsp945L45LttAttG22AY.90.000135
ORF1ab/nsp945L45LTtaCta22AY.920.000575
ORF1ab/nsp945L45LttAttG22AY.99.10.003106
ORF1ab/nsp945L45LttAttG22B.1.1.1210.004854
ORF1ab/nsp945L45LttAttG22B.1.1.390.001019
ORF1ab/nsp945L45LttAttG22B.1.1.500.001358
ORF1ab/nsp945L45LttAttG22B.1.1.5260.007092
ORF1ab/nsp945L45LttAttG22B.1.1950.01005
ORF1ab/nsp945L45LttAttG22B.1.2360.004107
ORF1ab/nsp945L45LttAttG22B.1.351.30.001753
ORF1ab/nsp945L45LttAttG22B.1.3620.003082
ORF1ab/nsp945L45LttAttG22B.1.4800.004975
ORF1ab/nsp945L45LttAttG22B.1.6250.004706
ORF1ab/nsp945L45LttAttG22B.6.60.001778
ORF1ab/nsp945L45LttAttG22P.20.000373
ORF1ab/nsp945L45LttAttG22P.70.008734
ORF1ab/nsp945L45LttAttG22Q.80.00033
ORF1ab/nsp945L45LttAttG11A0.000387
ORF1ab/nsp945L45LttAttG11A.10.000282
ORF1ab/nsp945L45LttAttG11A.23.10.000704
ORF1ab/nsp945L45LttAttG11AD.20.000219
ORF1ab/nsp945L45LttAttG11AY.1040.001984
ORF1ab/nsp945L45LttAttG11AY.1050.000643
ORF1ab/nsp945L45LttAttG11AY.1090.00074
ORF1ab/nsp945L45LttAttG11AY.1160.000287
ORF1ab/nsp945L45LttAttG11AY.120.000316
ORF1ab/nsp945L45LttAttG11AY.120.20.001285
ORF1ab/nsp945L45LTtaCta11AY.160.00038
ORF1ab/nsp945L45LttAttG11AY.16.10.00047
ORF1ab/nsp945L45LttAttG11AY.20.000356
ORF1ab/nsp945L45LttAttG11AY.220.002092
ORF1ab/nsp945L45LTtaCta11AY.300.000396
ORF1ab/nsp945L45LttAttG11AY.4.10.000737
ORF1ab/nsp945L45LttAttG11AY.410.000294
ORF1ab/nsp945L45LttAttG11AY.46.40.000165
ORF1ab/nsp945L45LttAttG11AY.46.60.000072
ORF1ab/nsp945L45LttAttG11AY.530.000288
ORF1ab/nsp945L45LttAttG11AY.590.00053
ORF1ab/nsp945L45LTtaCta11AY.600.000938
ORF1ab/nsp945L45LttAttG11AY.630.000387
ORF1ab/nsp945L45LttAttG11AY.650.000533
ORF1ab/nsp945L45LttAttG11AY.700.000209
ORF1ab/nsp945L45LttAttG11AY.730.000665
ORF1ab/nsp945L45LttAttG11AY.840.000437
ORF1ab/nsp945L45LttAttG11AY.860.00083
ORF1ab/nsp945L45LttAttG11AY.9.2.10.001976
ORF1ab/nsp945L45LttAttG11AY.980.000079
ORF1ab/nsp945L45LttAttG11AY.99.20.000092
ORF1ab/nsp945L45LttAttG11B.1.1.1530.001095
ORF1ab/nsp945L45LttAttG11B.1.1.1700.001247
ORF1ab/nsp945L45LttAttG11B.1.1.1980.001468
ORF1ab/nsp945L45LttAttG11B.1.1.2430.004082
ORF1ab/nsp945L45LttAttG11B.1.1.2650.003155
ORF1ab/nsp945L45LttAttG11B.1.1.2770.000759
ORF1ab/nsp945L45LttAttG11B.1.1.3110.000358
ORF1ab/nsp945L45LTtaCta11B.1.1.3260.001761
ORF1ab/nsp945L45LttAttG11B.1.1.3720.000689
ORF1ab/nsp945L45LttAttG11B.1.1.4160.000905
ORF1ab/nsp945L45LttAttG11B.1.1.4860.001577
ORF1ab/nsp945L45LttAttG11B.1.1.990.02381
ORF1ab/nsp945L45LttAttG11B.1.1110.001175
ORF1ab/nsp945L45LttAttG11B.1.1580.02381
ORF1ab/nsp945L45LttAttG11B.1.177.100.000878
ORF1ab/nsp945L45LttAttG11B.1.177.210.000076
ORF1ab/nsp945L45LttAttG11B.1.177.500.004695
ORF1ab/nsp945L45LttAttG11B.1.177.730.000566
ORF1ab/nsp945L45LttAttG11B.1.177.860.000183
ORF1ab/nsp945L45LttAttG11B.1.2400.000216
ORF1ab/nsp945L45LttAttG11B.1.2410.000812
ORF1ab/nsp945L45LttAttG11B.1.3240.001605
ORF1ab/nsp945L45LttAttG11B.1.36.10.00114
ORF1ab/nsp945L45LttAttG11B.1.36.100.004785
ORF1ab/nsp945L45LttAttG11B.1.36.180.00042
ORF1ab/nsp945L45LttAttG11B.1.3990.001934
ORF1ab/nsp945L45LttAttG11B.1.4040.001302
ORF1ab/nsp945L45LttAttG11B.1.4280.00102
ORF1ab/nsp945L45LttAttG11B.1.438.10.000107
ORF1ab/nsp945L45LttAttG11B.1.4680.005714
ORF1ab/nsp945L45LttAttG11B.1.4990.00105
ORF1ab/nsp945L45LttAttG11B.1.5610.000397
ORF1ab/nsp945L45LttAttG11B.1.5650.00081
ORF1ab/nsp945L45LttAttG11B.1.5670.003333
ORF1ab/nsp945L45LttAttG11B.1.5770.000687
ORF1ab/nsp945L45LttAttG11B.1.5990.00365
ORF1ab/nsp945L45LttAttG11B.1.619.10.000641
ORF1ab/nsp945L45LttAttG11B.1.88.10.004808
ORF1ab/nsp945L45LttAttG11C.180.002591
ORF1ab/nsp945L45LttAttG11C.230.005814
ORF1ab/nsp945L45LttAttG11D.20.000075
ORF1ab/nsp945L45LttAttG11P.1.10.000318
ORF1ab/nsp945L45LttAttG11P.1.130.000898
ORF1ab/nsp945L45LttAttG11P.1.150.000232
ORF1ab/nsp945L45LttAttG11P.1.170.000162
ORF1ab/nsp945L45LttAttG11P.1.60.001946
ORF1ab/nsp945L45LttAttG11P.1.70.000319
ORF1ab/nsp945L45LttAttG11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.