CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp9 : Mut = L42L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp942L42LL4182LsynctTctA173914840.85336412809-12811
ORF1ab/nsp942L42LL4182LsynctTctC17392300.1322612809-12811
ORF1ab/nsp942L42LL4182LsynctTctG1739240.01380112809-12811
ORF1ab/nsp942L42LL4182LsynCtTTtA173910.00057504312809-12811

Details of the mutation L42L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp942L42LctTctA14841739All0.000284
ORF1ab/nsp942L42LctTctC2301739All0.000044
ORF1ab/nsp942L42LctTctG241739All0.000005
ORF1ab/nsp942L42LCtTTtA11739All0
ORF1ab/nsp942L42LctTctA13581358B.1.5260.031919
ORF1ab/nsp942L42LctTctC5959B.1.5650.047812
ORF1ab/nsp942L42LctTctA1735B.1.1.70.000015
ORF1ab/nsp942L42LctTctC1735B.1.1.70.000015
ORF1ab/nsp942L42LCtTTtA135B.1.1.70.000001
ORF1ab/nsp942L42LctTctA2729P.10.000425
ORF1ab/nsp942L42LctTctC229P.10.000032
ORF1ab/nsp942L42LctTctC2828AY.260.000793
ORF1ab/nsp942L42LctTctC2828B.1.4270.001414
ORF1ab/nsp942L42LctTctC1919B.1.1600.000593
ORF1ab/nsp942L42LctTctA916B.1.617.20.000034
ORF1ab/nsp942L42LctTctC516B.1.617.20.000019
ORF1ab/nsp942L42LctTctG216B.1.617.20.000008
ORF1ab/nsp942L42LctTctG1515B.1.1.280.004669
ORF1ab/nsp942L42LctTctA914B.1.10.000163
ORF1ab/nsp942L42LctTctG314B.1.10.000054
ORF1ab/nsp942L42LctTctC214B.1.10.000036
ORF1ab/nsp942L42LctTctC59AY.130.000805
ORF1ab/nsp942L42LctTctA49AY.130.000644
ORF1ab/nsp942L42LctTctC99AY.290.000142
ORF1ab/nsp942L42LctTctA89B.1.4290.000188
ORF1ab/nsp942L42LctTctC19B.1.4290.000024
ORF1ab/nsp942L42LctTctC48AY.250.000024
ORF1ab/nsp942L42LctTctA48AY.250.000024
ORF1ab/nsp942L42LctTctC68AY.40.000009
ORF1ab/nsp942L42LctTctA28AY.40.000003
ORF1ab/nsp942L42LctTctA58AY.440.00003
ORF1ab/nsp942L42LctTctC38AY.440.000018
ORF1ab/nsp942L42LctTctC48B.10.000037
ORF1ab/nsp942L42LctTctA38B.10.000027
ORF1ab/nsp942L42LctTctG18B.10.000009
ORF1ab/nsp942L42LctTctC67B.1.3510.000178
ORF1ab/nsp942L42LctTctA17B.1.3510.00003
ORF1ab/nsp942L42LctTctA66AY.4.20.00013
ORF1ab/nsp942L42LctTctA46B.1.20.000035
ORF1ab/nsp942L42LctTctC26B.1.20.000018
ORF1ab/nsp942L42LctTctA55AY.1020.000133
ORF1ab/nsp942L42LctTctC55B.1.1700.021552
ORF1ab/nsp942L42LctTctC44AY.99.20.000369
ORF1ab/nsp942L42LctTctA23AY.430.000009
ORF1ab/nsp942L42LctTctC13AY.430.000004
ORF1ab/nsp942L42LctTctC23AY.470.000062
ORF1ab/nsp942L42LctTctA13AY.470.000031
ORF1ab/nsp942L42LctTctA33AY.630.001161
ORF1ab/nsp942L42LctTctA33C.370.000348
ORF1ab/nsp942L42LctTctC12AY.230.00007
ORF1ab/nsp942L42LctTctA12AY.230.00007
ORF1ab/nsp942L42LctTctA22AY.540.000191
ORF1ab/nsp942L42LctTctA22B.1.6200.001892
ORF1ab/nsp942L42LctTctC11AY.1030.000006
ORF1ab/nsp942L42LctTctA11AY.1100.000113
ORF1ab/nsp942L42LctTctC11AY.1170.000085
ORF1ab/nsp942L42LctTctC11AY.1180.000063
ORF1ab/nsp942L42LctTctC11AY.200.000039
ORF1ab/nsp942L42LctTctA11AY.320.000532
ORF1ab/nsp942L42LctTctC11AY.360.000148
ORF1ab/nsp942L42LctTctA11AY.390.000025
ORF1ab/nsp942L42LctTctG11AY.590.00053
ORF1ab/nsp942L42LctTctC11AY.690.000187
ORF1ab/nsp942L42LctTctC11AY.980.000079
ORF1ab/nsp942L42LctTctA11B.1.1.3060.000438
ORF1ab/nsp942L42LctTctC11B.1.1.3170.000412
ORF1ab/nsp942L42LctTctA11B.1.1.5070.008696
ORF1ab/nsp942L42LctTctC11B.1.1280.000635
ORF1ab/nsp942L42LctTctC11B.1.1390.000733
ORF1ab/nsp942L42LctTctC11B.1.160.110.005714
ORF1ab/nsp942L42LctTctC11B.1.1770.000013
ORF1ab/nsp942L42LctTctA11B.1.177.620.001192
ORF1ab/nsp942L42LctTctC11B.1.2500.014493
ORF1ab/nsp942L42LctTctG11B.1.3320.003497
ORF1ab/nsp942L42LctTctC11B.1.3780.006849
ORF1ab/nsp942L42LctTctG11B.1.3890.001002
ORF1ab/nsp942L42LctTctA11B.1.466.20.000391
ORF1ab/nsp942L42LctTctC11B.1.5240.001406
ORF1ab/nsp942L42LctTctA11B.1.5250.000113
ORF1ab/nsp942L42LctTctC11B.1.5600.00463
ORF1ab/nsp942L42LctTctC11B.1.5960.000087

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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