CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp9 : Mut = A15A

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp915A15AA4155AsyngcTgcG8904630.52022512728-12730
ORF1ab/nsp915A15AA4155AsyngcTgcC8903270.36741612728-12730
ORF1ab/nsp915A15AA4155AsyngcTgcA8901000.1123612728-12730

Details of the mutation A15A within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp915A15AgcTgcG463890All0.000089
ORF1ab/nsp915A15AgcTgcC327890All0.000063
ORF1ab/nsp915A15AgcTgcA100890All0.000019
ORF1ab/nsp915A15AgcTgcG406406B.1.6250.955294
ORF1ab/nsp915A15AgcTgcC88124B.1.1.70.000079
ORF1ab/nsp915A15AgcTgcA36124B.1.1.70.000032
ORF1ab/nsp915A15AgcTgcC5562AY.40.000086
ORF1ab/nsp915A15AgcTgcA462AY.40.000006
ORF1ab/nsp915A15AgcTgcG362AY.40.000005
ORF1ab/nsp915A15AgcTgcG3137B.10.000284
ORF1ab/nsp915A15AgcTgcA437B.10.000037
ORF1ab/nsp915A15AgcTgcC237B.10.000018
ORF1ab/nsp915A15AgcTgcC3536B.1.258.170.003639
ORF1ab/nsp915A15AgcTgcA136B.1.258.170.000104
ORF1ab/nsp915A15AgcTgcC3030B.1.20.000264
ORF1ab/nsp915A15AgcTgcC2225AY.1030.000137
ORF1ab/nsp915A15AgcTgcA225AY.1030.000012
ORF1ab/nsp915A15AgcTgcG125AY.1030.000006
ORF1ab/nsp915A15AgcTgcG1214AY.250.000072
ORF1ab/nsp915A15AgcTgcC214AY.250.000012
ORF1ab/nsp915A15AgcTgcC713P.10.00011
ORF1ab/nsp915A15AgcTgcA513P.10.000079
ORF1ab/nsp915A15AgcTgcG113P.10.000016
ORF1ab/nsp915A15AgcTgcC1011B.1.617.20.000038
ORF1ab/nsp915A15AgcTgcA111B.1.617.20.000004
ORF1ab/nsp915A15AgcTgcC99AY.1090.006657
ORF1ab/nsp915A15AgcTgcC99AY.430.00004
ORF1ab/nsp915A15AgcTgcC46AY.440.000024
ORF1ab/nsp915A15AgcTgcA26AY.440.000012
ORF1ab/nsp915A15AgcTgcC46B.1.10.000073
ORF1ab/nsp915A15AgcTgcA26B.1.10.000036
ORF1ab/nsp915A15AgcTgcC55AY.60.000206
ORF1ab/nsp915A15AgcTgcA45B.1.617.10.000516
ORF1ab/nsp915A15AgcTgcC15B.1.617.10.000129
ORF1ab/nsp915A15AgcTgcC44AY.4.20.000087
ORF1ab/nsp915A15AgcTgcC44B.1.1.3740.009501
ORF1ab/nsp915A15AgcTgcC44B.1.1.700.001364
ORF1ab/nsp915A15AgcTgcA44B.1.1490.013699
ORF1ab/nsp915A15AgcTgcC34B.1.1770.00004
ORF1ab/nsp915A15AgcTgcA14B.1.1770.000013
ORF1ab/nsp915A15AgcTgcA34B.1.4290.000071
ORF1ab/nsp915A15AgcTgcC14B.1.4290.000024
ORF1ab/nsp915A15AgcTgcA23AY.30.00002
ORF1ab/nsp915A15AgcTgcG13AY.30.00001
ORF1ab/nsp915A15AgcTgcC33B.4.70.030303
ORF1ab/nsp915A15AgcTgcC220.111111
ORF1ab/nsp915A15AgcTgcA12AY.1020.000027
ORF1ab/nsp915A15AgcTgcC12AY.1020.000027
ORF1ab/nsp915A15AgcTgcC22AY.130.000322
ORF1ab/nsp915A15AgcTgcA22AY.200.000078
ORF1ab/nsp915A15AgcTgcC22AY.46.40.000329
ORF1ab/nsp915A15AgcTgcA22AY.570.001312
ORF1ab/nsp915A15AgcTgcC12AY.750.000056
ORF1ab/nsp915A15AgcTgcA12AY.750.000056
ORF1ab/nsp915A15AgcTgcA22B.1.1.3370.007194
ORF1ab/nsp915A15AgcTgcG22B.1.1280.001271
ORF1ab/nsp915A15AgcTgcG12B.1.1600.000031
ORF1ab/nsp915A15AgcTgcA12B.1.1600.000031
ORF1ab/nsp915A15AgcTgcA22B.1.3510.000059
ORF1ab/nsp915A15AgcTgcC22C.370.000232
ORF1ab/nsp915A15AgcTgcA12D.20.000075
ORF1ab/nsp915A15AgcTgcC12D.20.000075
ORF1ab/nsp915A15AgcTgcG11A.230.010526
ORF1ab/nsp915A15AgcTgcC11AK.20.045455
ORF1ab/nsp915A15AgcTgcC11AY.1000.000046
ORF1ab/nsp915A15AgcTgcA11AY.1130.000142
ORF1ab/nsp915A15AgcTgcC11AY.1140.000231
ORF1ab/nsp915A15AgcTgcA11AY.1190.000035
ORF1ab/nsp915A15AgcTgcC11AY.1200.000037
ORF1ab/nsp915A15AgcTgcC11AY.20.000356
ORF1ab/nsp915A15AgcTgcA11AY.290.000016
ORF1ab/nsp915A15AgcTgcA11AY.29.10.000221
ORF1ab/nsp915A15AgcTgcA11AY.330.000067
ORF1ab/nsp915A15AgcTgcC11AY.50.000021
ORF1ab/nsp915A15AgcTgcA11AY.5.40.000277
ORF1ab/nsp915A15AgcTgcC11AY.740.000116
ORF1ab/nsp915A15AgcTgcC11AY.9.20.000037
ORF1ab/nsp915A15AgcTgcA11AZ.30.00152
ORF1ab/nsp915A15AgcTgcA11B.1.1.1740.003378
ORF1ab/nsp915A15AgcTgcG11B.1.1.260.005236
ORF1ab/nsp915A15AgcTgcA11B.1.1.3160.000925
ORF1ab/nsp915A15AgcTgcA11B.1.1.3690.000446
ORF1ab/nsp915A15AgcTgcG11B.1.1.5070.008696
ORF1ab/nsp915A15AgcTgcA11B.1.177.100.000878
ORF1ab/nsp915A15AgcTgcC11B.1.177.180.00116
ORF1ab/nsp915A15AgcTgcC11B.1.177.650.000665
ORF1ab/nsp915A15AgcTgcG11B.1.214.20.0006
ORF1ab/nsp915A15AgcTgcA11B.1.2580.000067
ORF1ab/nsp915A15AgcTgcA11B.1.360.000146
ORF1ab/nsp915A15AgcTgcC11B.1.4590.004082
ORF1ab/nsp915A15AgcTgcC11B.1.5230.002451
ORF1ab/nsp915A15AgcTgcA11B.1.5260.000024
ORF1ab/nsp915A15AgcTgcC11B.1.5960.000087
ORF1ab/nsp915A15AgcTgcG11B.1.90.006173
ORF1ab/nsp915A15AgcTgcA11B.60.00091
ORF1ab/nsp915A15AgcTgcA11N.50.001767
ORF1ab/nsp915A15AgcTgcC11P.1.120.000484
ORF1ab/nsp915A15AgcTgcA11P.1.60.001946

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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