CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp8 : Mut = S4L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp84S4LS3946LnonsyntCatTa664664112101-12103

Details of the mutation S4L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp84S4LtCatTa664664All0.000127
ORF1ab/nsp84S4LtCatTa125125B.1.1.70.000112
ORF1ab/nsp84S4LtCatTa8585B.1.5260.001998
ORF1ab/nsp84S4LtCatTa6464AY.40.0001
ORF1ab/nsp84S4LtCatTa3434B.1.617.20.000128
ORF1ab/nsp84S4LtCatTa2626B.10.000238
ORF1ab/nsp84S4LtCatTa2626B.1.1.1810.118182
ORF1ab/nsp84S4LtCatTa2121AY.30.000209
ORF1ab/nsp84S4LtCatTa2020AY.290.000315
ORF1ab/nsp84S4LtCatTa1717P.10.000268
ORF1ab/nsp84S4LtCatTa1616AY.250.000096
ORF1ab/nsp84S4LtCatTa1515AY.430.000066
ORF1ab/nsp84S4LtCatTa1414AY.740.001619
ORF1ab/nsp84S4LtCatTa1414B.1.10.000254
ORF1ab/nsp84S4LtCatTa1212AY.440.000073
ORF1ab/nsp84S4LtCatTa99AY.390.000222
ORF1ab/nsp84S4LtCatTa99B.1.1770.000119
ORF1ab/nsp84S4LtCatTa88B.1.20.00007
ORF1ab/nsp84S4LtCatTa77AY.50.000145
ORF1ab/nsp84S4LtCatTa55B.1.4290.000118
ORF1ab/nsp84S4LtCatTa55B.1.438.10.000536
ORF1ab/nsp84S4LtCatTa44AY.1030.000025
ORF1ab/nsp84S4LtCatTa44AY.1180.000251
ORF1ab/nsp84S4LtCatTa44AY.9.10.000335
ORF1ab/nsp84S4LtCatTa44B.1.1.500.002716
ORF1ab/nsp84S4LtCatTa44B.1.2210.000284
ORF1ab/nsp84S4LtCatTa33AY.130.000483
ORF1ab/nsp84S4LtCatTa33AY.260.000085
ORF1ab/nsp84S4LtCatTa33AY.330.0002
ORF1ab/nsp84S4LtCatTa33AY.470.000093
ORF1ab/nsp84S4LtCatTa33B.1.5250.000339
ORF1ab/nsp84S4LtCatTa33L.10.005714
ORF1ab/nsp84S4LtCatTa22AY.1020.000053
ORF1ab/nsp84S4LtCatTa22AY.1100.000225
ORF1ab/nsp84S4LtCatTa22AY.39.10.000079
ORF1ab/nsp84S4LtCatTa22AY.420.00008
ORF1ab/nsp84S4LtCatTa22AY.600.001876
ORF1ab/nsp84S4LtCatTa22AY.75.10.000361
ORF1ab/nsp84S4LtCatTa22AY.980.000158
ORF1ab/nsp84S4LtCatTa22AY.98.10.000097
ORF1ab/nsp84S4LtCatTa22B.1.1.5190.000079
ORF1ab/nsp84S4LtCatTa22B.1.177.810.000379
ORF1ab/nsp84S4LtCatTa22B.1.2430.000139
ORF1ab/nsp84S4LtCatTa22B.1.3510.000059
ORF1ab/nsp84S4LtCatTa22B.1.351.20.000605
ORF1ab/nsp84S4LtCatTa22B.1.4270.000101
ORF1ab/nsp84S4LtCatTa22B.1.617.10.000258
ORF1ab/nsp84S4LtCatTa22D.20.00015
ORF1ab/nsp84S4LtCatTa11AA.70.009174
ORF1ab/nsp84S4LtCatTa11AY.1170.000085
ORF1ab/nsp84S4LtCatTa11AY.1190.000035
ORF1ab/nsp84S4LtCatTa11AY.120.000316
ORF1ab/nsp84S4LtCatTa11AY.1200.000037
ORF1ab/nsp84S4LtCatTa11AY.1210.000135
ORF1ab/nsp84S4LtCatTa11AY.200.000039
ORF1ab/nsp84S4LtCatTa11AY.23.10.000417
ORF1ab/nsp84S4LtCatTa11AY.270.000065
ORF1ab/nsp84S4LtCatTa11AY.29.10.000221
ORF1ab/nsp84S4LtCatTa11AY.300.000396
ORF1ab/nsp84S4LtCatTa11AY.34.10.00051
ORF1ab/nsp84S4LtCatTa11AY.4.2.10.000149
ORF1ab/nsp84S4LtCatTa11AY.46.10.001027
ORF1ab/nsp84S4LtCatTa11AY.520.000814
ORF1ab/nsp84S4LtCatTa11AY.530.000288
ORF1ab/nsp84S4LtCatTa11AY.540.000095
ORF1ab/nsp84S4LtCatTa11AY.60.000041
ORF1ab/nsp84S4LtCatTa11AY.660.00107
ORF1ab/nsp84S4LtCatTa11AY.7.10.000113
ORF1ab/nsp84S4LtCatTa11AY.700.000209
ORF1ab/nsp84S4LtCatTa11AY.860.00083
ORF1ab/nsp84S4LtCatTa11AY.90.000068
ORF1ab/nsp84S4LtCatTa11AY.950.000761
ORF1ab/nsp84S4LtCatTa11B.1.1.10.000327
ORF1ab/nsp84S4LtCatTa11B.1.1.1700.001247
ORF1ab/nsp84S4LtCatTa11B.1.1.1760.000439
ORF1ab/nsp84S4LtCatTa11B.1.1.1980.001468
ORF1ab/nsp84S4LtCatTa11B.1.1.250.000569
ORF1ab/nsp84S4LtCatTa11B.1.1.280.000311
ORF1ab/nsp84S4LtCatTa11B.1.1.3060.000438
ORF1ab/nsp84S4LtCatTa11B.1.1.3160.000925
ORF1ab/nsp84S4LtCatTa11B.1.1.3550.015385
ORF1ab/nsp84S4LtCatTa11B.1.1.3910.008547
ORF1ab/nsp84S4LtCatTa11B.1.1.5000.02
ORF1ab/nsp84S4LtCatTa11B.1.1.580.005376
ORF1ab/nsp84S4LtCatTa11B.1.177.100.000878
ORF1ab/nsp84S4LtCatTa11B.1.177.210.000076
ORF1ab/nsp84S4LtCatTa11B.1.177.410.0025
ORF1ab/nsp84S4LtCatTa11B.1.177.420.000894
ORF1ab/nsp84S4LtCatTa11B.1.177.520.001757
ORF1ab/nsp84S4LtCatTa11B.1.177.860.000183
ORF1ab/nsp84S4LtCatTa11B.1.1820.007246
ORF1ab/nsp84S4LtCatTa11B.1.220.001318
ORF1ab/nsp84S4LtCatTa11B.1.2600.003344
ORF1ab/nsp84S4LtCatTa11B.1.3110.000275
ORF1ab/nsp84S4LtCatTa11B.1.360.000146
ORF1ab/nsp84S4LtCatTa11B.1.3780.006849
ORF1ab/nsp84S4LtCatTa11B.1.4600.017857
ORF1ab/nsp84S4LtCatTa11B.1.466.20.000391
ORF1ab/nsp84S4LtCatTa11B.1.4700.001404
ORF1ab/nsp84S4LtCatTa11B.1.5960.000087
ORF1ab/nsp84S4LtCatTa11B.1.6020.006536
ORF1ab/nsp84S4LtCatTa11B.1.6280.000352
ORF1ab/nsp84S4LtCatTa11B.1.6340.003425
ORF1ab/nsp84S4LtCatTa11B.400.000364
ORF1ab/nsp84S4LtCatTa11C.160.00106
ORF1ab/nsp84S4LtCatTa11C.190.027027
ORF1ab/nsp84S4LtCatTa11P.1.150.000232
ORF1ab/nsp84S4LtCatTa11P.1.170.000162
ORF1ab/nsp84S4LtCatTa11P.1.80.004785
ORF1ab/nsp84S4LtCatTa11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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