CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp8 : Mut = D175D

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp8175D175DD4117DsyngaCgaT14641464112614-12616

Details of the mutation D175D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp8175D175DgaCgaT14641464All0.00028
ORF1ab/nsp8175D175DgaCgaT560560B.1.36.310.980736
ORF1ab/nsp8175D175DgaCgaT264264B.1.5990.963504
ORF1ab/nsp8175D175DgaCgaT114114B.1.1.70.000102
ORF1ab/nsp8175D175DgaCgaT6363B.1.6050.375
ORF1ab/nsp8175D175DgaCgaT3838B.10.000348
ORF1ab/nsp8175D175DgaCgaT3737AY.40.000058
ORF1ab/nsp8175D175DgaCgaT3333B.1.617.20.000124
ORF1ab/nsp8175D175DgaCgaT2525P.1.170.004044
ORF1ab/nsp8175D175DgaCgaT2323AY.470.000715
ORF1ab/nsp8175D175DgaCgaT2222AY.250.000132
ORF1ab/nsp8175D175DgaCgaT2222AY.440.000134
ORF1ab/nsp8175D175DgaCgaT2020B.1.2470.298507
ORF1ab/nsp8175D175DgaCgaT1515B.1.1770.000198
ORF1ab/nsp8175D175DgaCgaT1414B.1.360.002043
ORF1ab/nsp8175D175DgaCgaT1212B.1.36.80.012
ORF1ab/nsp8175D175DgaCgaT1111AY.1030.000068
ORF1ab/nsp8175D175DgaCgaT1010P.1.100.002695
ORF1ab/nsp8175D175DgaCgaT99B.1.20.000079
ORF1ab/nsp8175D175DgaCgaT99B.1.4290.000212
ORF1ab/nsp8175D175DgaCgaT88P.10.000126
ORF1ab/nsp8175D175DgaCgaT77AY.740.00081
ORF1ab/nsp8175D175DgaCgaT77B.1.10.000127
ORF1ab/nsp8175D175DgaCgaT77B.1.36.170.003458
ORF1ab/nsp8175D175DgaCgaT66B.1.1.3170.00247
ORF1ab/nsp8175D175DgaCgaT66B.1.1600.000187
ORF1ab/nsp8175D175DgaCgaT66B.1.2430.000418
ORF1ab/nsp8175D175DgaCgaT66B.1.5260.000141
ORF1ab/nsp8175D175DgaCgaT55AY.430.000022
ORF1ab/nsp8175D175DgaCgaT55B.1.1.5190.000199
ORF1ab/nsp8175D175DgaCgaT44AY.1020.000106
ORF1ab/nsp8175D175DgaCgaT44AY.1170.000338
ORF1ab/nsp8175D175DgaCgaT44B.1.3960.002823
ORF1ab/nsp8175D175DgaCgaT33AY.30.00003
ORF1ab/nsp8175D175DgaCgaT33AY.610.000314
ORF1ab/nsp8175D175DgaCgaT33AY.98.10.000145
ORF1ab/nsp8175D175DgaCgaT33B.1.3110.000824
ORF1ab/nsp8175D175DgaCgaT33B.1.3690.000856
ORF1ab/nsp8175D175DgaCgaT33B.1.5820.001472
ORF1ab/nsp8175D175DgaCgaT33B.1.5870.005693
ORF1ab/nsp8175D175DgaCgaT33C.370.000348
ORF1ab/nsp8175D175DgaCgaT220.111111
ORF1ab/nsp8175D175DgaCgaT22AY.260.000057
ORF1ab/nsp8175D175DgaCgaT22AY.39.10.000079
ORF1ab/nsp8175D175DgaCgaT22AY.5.40.000553
ORF1ab/nsp8175D175DgaCgaT22AY.710.00095
ORF1ab/nsp8175D175DgaCgaT22AY.75.10.000361
ORF1ab/nsp8175D175DgaCgaT22B.1.1.1570.001826
ORF1ab/nsp8175D175DgaCgaT22B.1.4000.000858
ORF1ab/nsp8175D175DgaCgaT11A.10.000282
ORF1ab/nsp8175D175DgaCgaT11AY.1000.000046
ORF1ab/nsp8175D175DgaCgaT11AY.1180.000063
ORF1ab/nsp8175D175DgaCgaT11AY.1190.000035
ORF1ab/nsp8175D175DgaCgaT11AY.120.10.000321
ORF1ab/nsp8175D175DgaCgaT11AY.290.000016
ORF1ab/nsp8175D175DgaCgaT11AY.390.000025
ORF1ab/nsp8175D175DgaCgaT11AY.4.20.000022
ORF1ab/nsp8175D175DgaCgaT11AY.50.000021
ORF1ab/nsp8175D175DgaCgaT11AY.690.000187
ORF1ab/nsp8175D175DgaCgaT11AY.990.001049
ORF1ab/nsp8175D175DgaCgaT11AY.99.10.001553
ORF1ab/nsp8175D175DgaCgaT11B.1.1.1210.002427
ORF1ab/nsp8175D175DgaCgaT11B.1.1.2220.000204
ORF1ab/nsp8175D175DgaCgaT11B.1.1.2630.001558
ORF1ab/nsp8175D175DgaCgaT11B.1.1.2770.000759
ORF1ab/nsp8175D175DgaCgaT11B.1.1.2840.000107
ORF1ab/nsp8175D175DgaCgaT11B.1.1.2970.002237
ORF1ab/nsp8175D175DgaCgaT11B.1.1.3180.000302
ORF1ab/nsp8175D175DgaCgaT11B.1.1.3480.000796
ORF1ab/nsp8175D175DgaCgaT11B.1.1.370.000193
ORF1ab/nsp8175D175DgaCgaT11B.1.1.390.00051
ORF1ab/nsp8175D175DgaCgaT11B.1.1.4340.000349
ORF1ab/nsp8175D175DgaCgaT11B.1.1.4400.011765
ORF1ab/nsp8175D175DgaCgaT11B.1.160.220.006757
ORF1ab/nsp8175D175DgaCgaT11B.1.177.210.000076
ORF1ab/nsp8175D175DgaCgaT11B.1.177.570.000281
ORF1ab/nsp8175D175DgaCgaT11B.1.230.006061
ORF1ab/nsp8175D175DgaCgaT11B.1.258.30.001675
ORF1ab/nsp8175D175DgaCgaT11B.1.3510.00003
ORF1ab/nsp8175D175DgaCgaT11B.1.351.30.000876
ORF1ab/nsp8175D175DgaCgaT11B.1.3670.000792
ORF1ab/nsp8175D175DgaCgaT11B.1.4220.000812
ORF1ab/nsp8175D175DgaCgaT11B.1.4270.00005
ORF1ab/nsp8175D175DgaCgaT11B.1.466.20.000391
ORF1ab/nsp8175D175DgaCgaT11B.1.5240.001406
ORF1ab/nsp8175D175DgaCgaT11B.1.5250.000113
ORF1ab/nsp8175D175DgaCgaT11B.1.5640.000426
ORF1ab/nsp8175D175DgaCgaT11B.1.5960.000087
ORF1ab/nsp8175D175DgaCgaT11B.1.6090.000479
ORF1ab/nsp8175D175DgaCgaT11B.200.023256
ORF1ab/nsp8175D175DgaCgaT11B.3.10.001658
ORF1ab/nsp8175D175DgaCgaT11C.160.00106
ORF1ab/nsp8175D175DgaCgaT11C.360.000911
ORF1ab/nsp8175D175DgaCgaT11D.20.000075
ORF1ab/nsp8175D175DgaCgaT11P.1.150.000232
ORF1ab/nsp8175D175DgaCgaT11Q.10.000126
ORF1ab/nsp8175D175DgaCgaT11W.10.008696

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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