CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp8 : Mut = A53T

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp853A53TA3995TnonsynGcaAca2562540.99218812248-12250
ORF1ab/nsp853A53TA3995TnonsynGcAAcT25620.007812512248-12250

Details of the mutation A53T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp853A53TGcaAca254256All0.000049
ORF1ab/nsp853A53TGcAAcT2256All0
ORF1ab/nsp853A53TGcaAca6567B.1.1.70.000058
ORF1ab/nsp853A53TGcAAcT267B.1.1.70.000002
ORF1ab/nsp853A53TGcaAca6565AY.40.000101
ORF1ab/nsp853A53TGcaAca2020AY.4.20.000434
ORF1ab/nsp853A53TGcaAca1414B.1.617.20.000053
ORF1ab/nsp853A53TGcaAca1111B.1.3510.000327
ORF1ab/nsp853A53TGcaAca1010AY.440.000061
ORF1ab/nsp853A53TGcaAca1010B.1.10.000181
ORF1ab/nsp853A53TGcaAca66AY.260.00017
ORF1ab/nsp853A53TGcaAca55B.1.1.3510.013966
ORF1ab/nsp853A53TGcaAca55P.10.000079
ORF1ab/nsp853A53TGcaAca44B.1.1600.000125
ORF1ab/nsp853A53TGcaAca44B.1.2580.000266
ORF1ab/nsp853A53TGcaAca33AY.250.000018
ORF1ab/nsp853A53TGcaAca33B.10.000027
ORF1ab/nsp853A53TGcaAca33B.1.1.1660.1
ORF1ab/nsp853A53TGcaAca22AY.1020.000053
ORF1ab/nsp853A53TGcaAca22AY.30.00002
ORF1ab/nsp853A53TGcaAca22AY.430.000009
ORF1ab/nsp853A53TGcaAca22B.1.6370.000146
ORF1ab/nsp853A53TGcaAca11AY.1000.000046
ORF1ab/nsp853A53TGcaAca11AY.1030.000006
ORF1ab/nsp853A53TGcaAca11AY.200.000039
ORF1ab/nsp853A53TGcaAca11AY.390.000025
ORF1ab/nsp853A53TGcaAca11AY.690.000187
ORF1ab/nsp853A53TGcaAca11B.1.1.1570.000913
ORF1ab/nsp853A53TGcaAca11B.1.1.2140.000055
ORF1ab/nsp853A53TGcaAca11B.1.177.230.003236
ORF1ab/nsp853A53TGcaAca11B.1.1790.003759
ORF1ab/nsp853A53TGcaAca11B.1.20.000009
ORF1ab/nsp853A53TGcaAca11B.1.4010.008197
ORF1ab/nsp853A53TGcaAca11B.1.4090.000781
ORF1ab/nsp853A53TGcaAca11B.1.438.10.000107
ORF1ab/nsp853A53TGcaAca11B.1.5270.003704
ORF1ab/nsp853A53TGcaAca11B.1.5750.000303
ORF1ab/nsp853A53TGcaAca11B.1.5760.000907
ORF1ab/nsp853A53TGcaAca11B.1.930.000934
ORF1ab/nsp853A53TGcaAca11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.