CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp8 : Mut = A53A

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp853A53AA3995AsyngcAgcT190110100.53129912248-12250
ORF1ab/nsp853A53AA3995AsyngcAgcG19018570.45081512248-12250
ORF1ab/nsp853A53AA3995AsyngcAgcC1901340.017885312248-12250

Details of the mutation A53A within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp853A53AgcAgcT10101901All0.000193
ORF1ab/nsp853A53AgcAgcG8571901All0.000164
ORF1ab/nsp853A53AgcAgcC341901All0.000007
ORF1ab/nsp853A53AgcAgcT816816AY.1100.091954
ORF1ab/nsp853A53AgcAgcG644650AY.40.001002
ORF1ab/nsp853A53AgcAgcC6650AY.40.000009
ORF1ab/nsp853A53AgcAgcT6767AY.160.025437
ORF1ab/nsp853A53AgcAgcT3961B.1.1.70.000035
ORF1ab/nsp853A53AgcAgcG1261B.1.1.70.000011
ORF1ab/nsp853A53AgcAgcC1061B.1.1.70.000009
ORF1ab/nsp853A53AgcAgcG5353AY.4.40.021686
ORF1ab/nsp853A53AgcAgcG1936B.1.617.20.000072
ORF1ab/nsp853A53AgcAgcT1636B.1.617.20.00006
ORF1ab/nsp853A53AgcAgcC136B.1.617.20.000004
ORF1ab/nsp853A53AgcAgcT2222AY.4.50.002365
ORF1ab/nsp853A53AgcAgcG2121B.1.36.380.034483
ORF1ab/nsp853A53AgcAgcG1214B.1.1770.000158
ORF1ab/nsp853A53AgcAgcT214B.1.1770.000026
ORF1ab/nsp853A53AgcAgcG1313D.20.000976
ORF1ab/nsp853A53AgcAgcT1010AY.300.003957
ORF1ab/nsp853A53AgcAgcG710P.10.00011
ORF1ab/nsp853A53AgcAgcT310P.10.000047
ORF1ab/nsp853A53AgcAgcG89P.1.140.000382
ORF1ab/nsp853A53AgcAgcT19P.1.140.000048
ORF1ab/nsp853A53AgcAgcG58AY.250.00003
ORF1ab/nsp853A53AgcAgcT28AY.250.000012
ORF1ab/nsp853A53AgcAgcC18AY.250.000006
ORF1ab/nsp853A53AgcAgcG68B.1.10.000109
ORF1ab/nsp853A53AgcAgcT28B.1.10.000036
ORF1ab/nsp853A53AgcAgcG88B.1.617.10.001032
ORF1ab/nsp853A53AgcAgcG47B.1.20.000035
ORF1ab/nsp853A53AgcAgcT37B.1.20.000026
ORF1ab/nsp853A53AgcAgcG66B.1.6210.000531
ORF1ab/nsp853A53AgcAgcG45AY.430.000018
ORF1ab/nsp853A53AgcAgcT15AY.430.000004
ORF1ab/nsp853A53AgcAgcC35B.10.000027
ORF1ab/nsp853A53AgcAgcT25B.10.000018
ORF1ab/nsp853A53AgcAgcT55B.1.5410.022124
ORF1ab/nsp853A53AgcAgcG34AY.440.000018
ORF1ab/nsp853A53AgcAgcT14AY.440.000006
ORF1ab/nsp853A53AgcAgcT44B.1.5260.000094
ORF1ab/nsp853A53AgcAgcC44P.40.015209
ORF1ab/nsp853A53AgcAgcG33AY.290.000047
ORF1ab/nsp853A53AgcAgcT22AY.1000.000092
ORF1ab/nsp853A53AgcAgcC12AY.1030.000006
ORF1ab/nsp853A53AgcAgcG12AY.1030.000006
ORF1ab/nsp853A53AgcAgcT22AY.1170.000169
ORF1ab/nsp853A53AgcAgcG22AY.1180.000125
ORF1ab/nsp853A53AgcAgcT12AY.30.00001
ORF1ab/nsp853A53AgcAgcG12AY.30.00001
ORF1ab/nsp853A53AgcAgcT12AY.360.000148
ORF1ab/nsp853A53AgcAgcG12AY.360.000148
ORF1ab/nsp853A53AgcAgcG22AY.390.000049
ORF1ab/nsp853A53AgcAgcC22AY.470.000062
ORF1ab/nsp853A53AgcAgcG22AY.610.00021
ORF1ab/nsp853A53AgcAgcT22AY.840.000875
ORF1ab/nsp853A53AgcAgcG22B.1.1.330.000842
ORF1ab/nsp853A53AgcAgcG22B.1.1.5190.000079
ORF1ab/nsp853A53AgcAgcC22B.1.5770.001375
ORF1ab/nsp853A53AgcAgcG22Q.30.00029
ORF1ab/nsp853A53AgcAgcG22R.10.00018
ORF1ab/nsp853A53AgcAgcT11AY.1110.000183
ORF1ab/nsp853A53AgcAgcG11AY.1190.000035
ORF1ab/nsp853A53AgcAgcT11AY.180.010101
ORF1ab/nsp853A53AgcAgcT11AY.230.00007
ORF1ab/nsp853A53AgcAgcG11AY.340.000097
ORF1ab/nsp853A53AgcAgcG11AY.350.000233
ORF1ab/nsp853A53AgcAgcC11AY.39.10.00004
ORF1ab/nsp853A53AgcAgcG11AY.420.00004
ORF1ab/nsp853A53AgcAgcG11AY.460.000104
ORF1ab/nsp853A53AgcAgcG11AY.570.000656
ORF1ab/nsp853A53AgcAgcT11AY.850.000427
ORF1ab/nsp853A53AgcAgcG11AY.870.000833
ORF1ab/nsp853A53AgcAgcT11AY.930.000273
ORF1ab/nsp853A53AgcAgcT11B0.000128
ORF1ab/nsp853A53AgcAgcG11B.1.1.2220.000204
ORF1ab/nsp853A53AgcAgcC11B.1.1110.001175
ORF1ab/nsp853A53AgcAgcC11B.1.1600.000031
ORF1ab/nsp853A53AgcAgcG11B.1.177.40.000211
ORF1ab/nsp853A53AgcAgcC11B.1.3910.001127
ORF1ab/nsp853A53AgcAgcG11B.1.4250.002994
ORF1ab/nsp853A53AgcAgcG11B.1.4270.00005
ORF1ab/nsp853A53AgcAgcG11P.1.40.000977

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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