CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp8 : Mut = A126A

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp8126A126AA4068AsyngcCgcT405435410.87345812467-12469
ORF1ab/nsp8126A126AA4068AsyngcCgcA40545090.12555512467-12469
ORF1ab/nsp8126A126AA4068AsyngcCgcG405440.0009866812467-12469

Details of the mutation A126A within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp8126A126AgcCgcT35414054All0.000677
ORF1ab/nsp8126A126AgcCgcA5094054All0.000097
ORF1ab/nsp8126A126AgcCgcG44054All0.000001
ORF1ab/nsp8126A126AgcCgcT17601781B.1.1.70.001576
ORF1ab/nsp8126A126AgcCgcA201781B.1.1.70.000018
ORF1ab/nsp8126A126AgcCgcG11781B.1.1.70.000001
ORF1ab/nsp8126A126AgcCgcT368368A.280.973545
ORF1ab/nsp8126A126AgcCgcT304304B.1.5250.034401
ORF1ab/nsp8126A126AgcCgcT171270AY.40.000266
ORF1ab/nsp8126A126AgcCgcA98270AY.40.000153
ORF1ab/nsp8126A126AgcCgcG1270AY.40.000002
ORF1ab/nsp8126A126AgcCgcA132255AY.430.000585
ORF1ab/nsp8126A126AgcCgcT123255AY.430.000545
ORF1ab/nsp8126A126AgcCgcT192234B.1.617.20.000723
ORF1ab/nsp8126A126AgcCgcA42234B.1.617.20.000158
ORF1ab/nsp8126A126AgcCgcT6983AY.30.000686
ORF1ab/nsp8126A126AgcCgcA1483AY.30.000139
ORF1ab/nsp8126A126AgcCgcT6565B.1.1.5190.002581
ORF1ab/nsp8126A126AgcCgcT5757B.1.5950.014875
ORF1ab/nsp8126A126AgcCgcT5151AY.4.20.001106
ORF1ab/nsp8126A126AgcCgcA4646AY.610.00482
ORF1ab/nsp8126A126AgcCgcT4145B.1.10.000744
ORF1ab/nsp8126A126AgcCgcA345B.1.10.000054
ORF1ab/nsp8126A126AgcCgcG145B.1.10.000018
ORF1ab/nsp8126A126AgcCgcT3141AY.440.000189
ORF1ab/nsp8126A126AgcCgcA1041AY.440.000061
ORF1ab/nsp8126A126AgcCgcT2638B.10.000238
ORF1ab/nsp8126A126AgcCgcA1238B.10.00011
ORF1ab/nsp8126A126AgcCgcA2735AY.1030.000168
ORF1ab/nsp8126A126AgcCgcT835AY.1030.00005
ORF1ab/nsp8126A126AgcCgcA1626B.1.20.000141
ORF1ab/nsp8126A126AgcCgcT1026B.1.20.000088
ORF1ab/nsp8126A126AgcCgcA2325AY.470.000715
ORF1ab/nsp8126A126AgcCgcT225AY.470.000062
ORF1ab/nsp8126A126AgcCgcT2020AY.1000.00092
ORF1ab/nsp8126A126AgcCgcT1919AY.1170.001606
ORF1ab/nsp8126A126AgcCgcT1718AY.750.000952
ORF1ab/nsp8126A126AgcCgcA118AY.750.000056
ORF1ab/nsp8126A126AgcCgcT1718P.10.000268
ORF1ab/nsp8126A126AgcCgcA118P.10.000016
ORF1ab/nsp8126A126AgcCgcA1317B.1.5260.000306
ORF1ab/nsp8126A126AgcCgcT417B.1.5260.000094
ORF1ab/nsp8126A126AgcCgcT1515A0.005805
ORF1ab/nsp8126A126AgcCgcA1415C.370.001625
ORF1ab/nsp8126A126AgcCgcT115C.370.000116
ORF1ab/nsp8126A126AgcCgcA813AY.290.000126
ORF1ab/nsp8126A126AgcCgcT513AY.290.000079
ORF1ab/nsp8126A126AgcCgcT1313Q.10.001642
ORF1ab/nsp8126A126AgcCgcT1111AY.260.000311
ORF1ab/nsp8126A126AgcCgcT59AY.250.00003
ORF1ab/nsp8126A126AgcCgcA49AY.250.000024
ORF1ab/nsp8126A126AgcCgcT88AY.200.000311
ORF1ab/nsp8126A126AgcCgcT66AY.640.003571
ORF1ab/nsp8126A126AgcCgcT56AY.980.000395
ORF1ab/nsp8126A126AgcCgcA16AY.980.000079
ORF1ab/nsp8126A126AgcCgcT66B.1.177.170.004926
ORF1ab/nsp8126A126AgcCgcA35B.1.1770.00004
ORF1ab/nsp8126A126AgcCgcT25B.1.1770.000026
ORF1ab/nsp8126A126AgcCgcT44AY.1210.000541
ORF1ab/nsp8126A126AgcCgcT44AY.240.001724
ORF1ab/nsp8126A126AgcCgcA44AY.420.000161
ORF1ab/nsp8126A126AgcCgcT44B0.000511
ORF1ab/nsp8126A126AgcCgcT24B.1.3510.000059
ORF1ab/nsp8126A126AgcCgcA24B.1.3510.000059
ORF1ab/nsp8126A126AgcCgcT44B.1.5170.001708
ORF1ab/nsp8126A126AgcCgcT33AY.1060.001005
ORF1ab/nsp8126A126AgcCgcA33AY.1080.003308
ORF1ab/nsp8126A126AgcCgcT33AY.540.000286
ORF1ab/nsp8126A126AgcCgcT33B.1.1.2220.000612
ORF1ab/nsp8126A126AgcCgcT33B.1.1.280.000934
ORF1ab/nsp8126A126AgcCgcT33B.1.177.730.001699
ORF1ab/nsp8126A126AgcCgcT33B.1.60.051724
ORF1ab/nsp8126A126AgcCgcT23B.1.617.10.000258
ORF1ab/nsp8126A126AgcCgcA13B.1.617.10.000129
ORF1ab/nsp8126A126AgcCgcT22A.30.004193
ORF1ab/nsp8126A126AgcCgcT22AW.10.006098
ORF1ab/nsp8126A126AgcCgcT22AY.1050.001286
ORF1ab/nsp8126A126AgcCgcT22AY.270.000129
ORF1ab/nsp8126A126AgcCgcT22AY.34.10.00102
ORF1ab/nsp8126A126AgcCgcT22AY.670.000929
ORF1ab/nsp8126A126AgcCgcT22AY.950.001522
ORF1ab/nsp8126A126AgcCgcT22B.1.1.2140.000111
ORF1ab/nsp8126A126AgcCgcT22B.1.2210.000142
ORF1ab/nsp8126A126AgcCgcT22B.1.3750.001639
ORF1ab/nsp8126A126AgcCgcT22B.1.428.20.066667
ORF1ab/nsp8126A126AgcCgcT22B.1.4290.000047
ORF1ab/nsp8126A126AgcCgcT22B.1.5960.000174
ORF1ab/nsp8126A126AgcCgcT22B.1.6280.000705
ORF1ab/nsp8126A126AgcCgcT22P.20.000373
ORF1ab/nsp8126A126AgcCgcT22Q.20.001227
ORF1ab/nsp8126A126AgcCgcT11A.120.166667
ORF1ab/nsp8126A126AgcCgcT11AY.10.000396
ORF1ab/nsp8126A126AgcCgcT11AY.1020.000027
ORF1ab/nsp8126A126AgcCgcT11AY.1090.00074
ORF1ab/nsp8126A126AgcCgcA11AY.1130.000142
ORF1ab/nsp8126A126AgcCgcT11AY.1180.000063
ORF1ab/nsp8126A126AgcCgcT11AY.20.000356
ORF1ab/nsp8126A126AgcCgcT11AY.230.00007
ORF1ab/nsp8126A126AgcCgcT11AY.29.10.000221
ORF1ab/nsp8126A126AgcCgcT11AY.360.000148
ORF1ab/nsp8126A126AgcCgcA11AY.390.000025
ORF1ab/nsp8126A126AgcCgcT11AY.460.000104
ORF1ab/nsp8126A126AgcCgcT11AY.46.20.000635
ORF1ab/nsp8126A126AgcCgcA11AY.5.30.000337
ORF1ab/nsp8126A126AgcCgcA11AY.620.000436
ORF1ab/nsp8126A126AgcCgcT11AY.740.000116
ORF1ab/nsp8126A126AgcCgcA11AY.75.10.00018
ORF1ab/nsp8126A126AgcCgcT11AY.840.000437
ORF1ab/nsp8126A126AgcCgcA11AY.98.10.000048
ORF1ab/nsp8126A126AgcCgcT11AY.99.20.000092
ORF1ab/nsp8126A126AgcCgcT11B.1.1.2770.000759
ORF1ab/nsp8126A126AgcCgcT11B.1.1.2940.001266
ORF1ab/nsp8126A126AgcCgcT11B.1.1.3060.000438
ORF1ab/nsp8126A126AgcCgcT11B.1.1.3160.000925
ORF1ab/nsp8126A126AgcCgcG11B.1.1.4090.002833
ORF1ab/nsp8126A126AgcCgcT11B.1.1.5070.008696
ORF1ab/nsp8126A126AgcCgcA11B.1.1.630.000386
ORF1ab/nsp8126A126AgcCgcT11B.1.1110.001175
ORF1ab/nsp8126A126AgcCgcT11B.1.177.210.000076
ORF1ab/nsp8126A126AgcCgcT11B.1.177.350.000691
ORF1ab/nsp8126A126AgcCgcT11B.1.177.440.000519
ORF1ab/nsp8126A126AgcCgcT11B.1.177.580.001332
ORF1ab/nsp8126A126AgcCgcT11B.1.177.810.000189
ORF1ab/nsp8126A126AgcCgcA11B.1.2100.002132
ORF1ab/nsp8126A126AgcCgcT11B.1.2340.000132
ORF1ab/nsp8126A126AgcCgcT11B.1.258.170.000104
ORF1ab/nsp8126A126AgcCgcT11B.1.3360.002439
ORF1ab/nsp8126A126AgcCgcT11B.1.3490.000715
ORF1ab/nsp8126A126AgcCgcT11B.1.360.000146
ORF1ab/nsp8126A126AgcCgcT11B.1.36.200.016949
ORF1ab/nsp8126A126AgcCgcT11B.1.3690.000285
ORF1ab/nsp8126A126AgcCgcT11B.1.416.10.001563
ORF1ab/nsp8126A126AgcCgcT11B.1.4270.00005
ORF1ab/nsp8126A126AgcCgcT11B.1.5510.00129
ORF1ab/nsp8126A126AgcCgcT11B.1.5710.009709
ORF1ab/nsp8126A126AgcCgcA11B.1.6270.00202
ORF1ab/nsp8126A126AgcCgcT11B.1.6370.000073
ORF1ab/nsp8126A126AgcCgcT11B.30.000831
ORF1ab/nsp8126A126AgcCgcA11B.400.000364
ORF1ab/nsp8126A126AgcCgcA11C.110.010638
ORF1ab/nsp8126A126AgcCgcT11P.1.40.000977

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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