CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp8 : CodonNum = 153

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp8153L153LL4095LsynttGttA3963050.77020212548-12550
ORF1ab/nsp8153L153LL4095LsynTtgCtg396910.22979812548-12550
ORF1ab/nsp8153L153VL4095VnonsynTtgGtg6363112548-12550
ORF1ab/nsp8153L153delL4095deldelTTG---2525112548-12550
ORF1ab/nsp8153L153FL4095FnonsynttGttT16140.87512548-12550
ORF1ab/nsp8153L153FL4095FnonsynttGttC1620.12512548-12550
ORF1ab/nsp8153L153SL4095SnonsyntTgtCg66112548-12550
ORF1ab/nsp8153L153IL4095InonsynTtGAtA540.812548-12550
ORF1ab/nsp8153L153IL4095InonsynTtGAtT510.212548-12550
ORF1ab/nsp8153L153EL4095EnonsynTTGGAA22112548-12550
ORF1ab/nsp8153L153RL4095RnonsynTTGCGA22112548-12550
ORF1ab/nsp8153L153TL4095TnonsynTTgACg22112548-12550
ORF1ab/nsp8153L153del2L4095del2deltTGt--22112548-12550
ORF1ab/nsp8153L153WL4095WnonsyntTgtGg11112548-12550
ORF1ab/nsp8153L153XL4095XnonsyntTgtAg11112548-12550
ORF1ab/nsp8153L153PL4095PnonsynTTgCCg11112548-12550
ORF1ab/nsp8153L153del1L4095del1delTtg-tg11112548-12550

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp8153L153LttGttA305396All0.000058
ORF1ab/nsp8153L153LTtgCtg91396All0.000017
ORF1ab/nsp8153L153LttGttA9494B.1.1900.94
ORF1ab/nsp8153L153LttGttA6577B.1.1.70.000058
ORF1ab/nsp8153L153LTtgCtg1277B.1.1.70.000011
ORF1ab/nsp8153L153VTtgGtg6363All0.000012
ORF1ab/nsp8153L153LttGttA3133AY.40.000048
ORF1ab/nsp8153L153LTtgCtg233AY.40.000003
ORF1ab/nsp8153L153VTtgGtg3232B.1.2210.002273
ORF1ab/nsp8153L153LTtgCtg2627AY.430.000115
ORF1ab/nsp8153L153LttGttA127AY.430.000004
ORF1ab/nsp8153L153VTtgGtg2727B.1.2400.00582
ORF1ab/nsp8153L153delTTG---2525All0.000005
ORF1ab/nsp8153L153LTtgCtg1621B.1.20.000141
ORF1ab/nsp8153L153LttGttA521B.1.20.000044
ORF1ab/nsp8153L153LttGttA1321B.1.617.20.000049
ORF1ab/nsp8153L153LTtgCtg821B.1.617.20.00003
ORF1ab/nsp8153L153FttGttT1416All0.000003
ORF1ab/nsp8153L153FttGttC216All0
ORF1ab/nsp8153L153LttGttA1616AY.290.000252
ORF1ab/nsp8153L153LttGttA1212B.1.177.790.028103
ORF1ab/nsp8153L153delTTG---77B.1.1.70.000006
ORF1ab/nsp8153L153StTgtCg66All0.000001
ORF1ab/nsp8153L153LTtgCtg66AY.1000.000276
ORF1ab/nsp8153L153LttGttA66AY.1030.000037
ORF1ab/nsp8153L153LttGttA56AY.440.00003
ORF1ab/nsp8153L153LTtgCtg16AY.440.000006
ORF1ab/nsp8153L153LttGttA66B.1.10.000109
ORF1ab/nsp8153L153LTtgCtg36P.10.000047
ORF1ab/nsp8153L153LttGttA36P.10.000047
ORF1ab/nsp8153L153ITtGAtA45All0.000001
ORF1ab/nsp8153L153ITtGAtT15All0
ORF1ab/nsp8153L153ITtGAtA440.222222
ORF1ab/nsp8153L153LttGttA44AY.1020.000106
ORF1ab/nsp8153L153LTtgCtg24AY.1190.000071
ORF1ab/nsp8153L153LttGttA24AY.1190.000071
ORF1ab/nsp8153L153LttGttA44AY.470.000124
ORF1ab/nsp8153L153LttGttA44B.10.000037
ORF1ab/nsp8153L153FttGttT44B.10.000037
ORF1ab/nsp8153L153LTtgCtg24B.1.4000.000858
ORF1ab/nsp8153L153LttGttA24B.1.4000.000858
ORF1ab/nsp8153L153LttGttA33AY.20.001068
ORF1ab/nsp8153L153LttGttA33AY.250.000018
ORF1ab/nsp8153L153LttGttA23AY.99.20.000184
ORF1ab/nsp8153L153LTtgCtg13AY.99.20.000092
ORF1ab/nsp8153L153LTtgCtg33B.1.1.3010.003538
ORF1ab/nsp8153L153LttGttA33B.1.1770.00004
ORF1ab/nsp8153L153RTTGCGA220.111111
ORF1ab/nsp8153L153ETTGGAA220.111111
ORF1ab/nsp8153L153del2tTGt--22All0
ORF1ab/nsp8153L153TTTgACg22All0
ORF1ab/nsp8153L153RTTGCGA22All0
ORF1ab/nsp8153L153ETTGGAA22All0
ORF1ab/nsp8153L153LttGttA22AY.110.002677
ORF1ab/nsp8153L153delTTG---22AY.250.000012
ORF1ab/nsp8153L153LttGttA22AY.30.00002
ORF1ab/nsp8153L153LttGttA22AY.340.000194
ORF1ab/nsp8153L153LttGttA22AY.420.00008
ORF1ab/nsp8153L153delTTG---22AY.430.000009
ORF1ab/nsp8153L153delTTG---22AY.750.000112
ORF1ab/nsp8153L153LttGttA22AY.9.10.000167
ORF1ab/nsp8153L153VTtgGtg22B.10.000018
ORF1ab/nsp8153L153StTgtCg22B.1.1.70.000002
ORF1ab/nsp8153L153FttGttT12B.1.1.70.000001
ORF1ab/nsp8153L153FttGttC12B.1.1.70.000001
ORF1ab/nsp8153L153del2tTGt--22B.1.20.000018
ORF1ab/nsp8153L153LttGttA22B.1.2430.000139
ORF1ab/nsp8153L153LTtgCtg22B.1.2580.000133
ORF1ab/nsp8153L153FttGttT22B.1.617.20.000008
ORF1ab/nsp8153L153LttGttA11A0.000387
ORF1ab/nsp8153L153LTtgCtg11A.210.00277
ORF1ab/nsp8153L153VTtgGtg11AD.20.000219
ORF1ab/nsp8153L153XtTgtAg11All0
ORF1ab/nsp8153L153WtTgtGg11All0
ORF1ab/nsp8153L153PTTgCCg11All0
ORF1ab/nsp8153L153del1Ttg-tg11All0
ORF1ab/nsp8153L153StTgtCg11AY.1110.000183
ORF1ab/nsp8153L153LTtgCtg11AY.1130.000142
ORF1ab/nsp8153L153ITtGAtT11AY.1180.000063
ORF1ab/nsp8153L153LttGttA11AY.260.000028
ORF1ab/nsp8153L153LttGttA11AY.34.10.00051
ORF1ab/nsp8153L153LttGttA11AY.380.000499
ORF1ab/nsp8153L153LttGttA11AY.390.000025
ORF1ab/nsp8153L153delTTG---11AY.4.50.000107
ORF1ab/nsp8153L153del1Ttg-tg11AY.440.000006
ORF1ab/nsp8153L153PTTgCCg11AY.440.000006
ORF1ab/nsp8153L153StTgtCg11AY.440.000006
ORF1ab/nsp8153L153delTTG---11AY.46.20.000635
ORF1ab/nsp8153L153XtTgtAg11AY.610.000105
ORF1ab/nsp8153L153delTTG---11AY.650.000533
ORF1ab/nsp8153L153LTtgCtg11AY.900.000684
ORF1ab/nsp8153L153delTTG---11B.10.000009
ORF1ab/nsp8153L153TTTgACg11B.1.10.000018
ORF1ab/nsp8153L153StTgtCg11B.1.1.2690.001353
ORF1ab/nsp8153L153delTTG---11B.1.1.280.000311
ORF1ab/nsp8153L153WtTgtGg11B.1.1.3000.010753
ORF1ab/nsp8153L153LttGttA11B.1.1.330.000421
ORF1ab/nsp8153L153StTgtCg11B.1.1.4340.000349
ORF1ab/nsp8153L153delTTG---11B.1.1.4480.002033
ORF1ab/nsp8153L153TTTgACg11B.1.1.70.000001
ORF1ab/nsp8153L153FttGttT11B.1.1390.000733
ORF1ab/nsp8153L153delTTG---11B.1.1770.000013
ORF1ab/nsp8153L153FttGttT11B.1.177.170.000821
ORF1ab/nsp8153L153LTtgCtg11B.1.177.540.000606
ORF1ab/nsp8153L153LttGttA11B.1.177.860.000183
ORF1ab/nsp8153L153LTtgCtg11B.1.2360.002053
ORF1ab/nsp8153L153LTtgCtg11B.1.360.000146
ORF1ab/nsp8153L153FttGttT11B.1.3990.001934
ORF1ab/nsp8153L153LTtgCtg11B.1.4290.000024
ORF1ab/nsp8153L153VTtgGtg11B.1.4590.004082
ORF1ab/nsp8153L153FttGttT11B.1.5260.000024
ORF1ab/nsp8153L153LttGttA11B.1.5260.000024
ORF1ab/nsp8153L153FttGttT11B.1.5650.00081
ORF1ab/nsp8153L153delTTG---11B.1.617.20.000004
ORF1ab/nsp8153L153delTTG---11B.340.013699
ORF1ab/nsp8153L153FttGttT11B.60.00091
ORF1ab/nsp8153L153delTTG---11C.360.000911
ORF1ab/nsp8153L153FttGttC11C.370.000116
ORF1ab/nsp8153L153FttGttT11D.20.000075
ORF1ab/nsp8153L153delTTG---11N.40.004255
ORF1ab/nsp8153L153LttGttA11P.20.000187
ORF1ab/nsp8153L153delTTG---11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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