CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp8 : CodonNum = 143

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp8143D143GD4085GnonsyngAtgGt149714950.99866412518-12520
ORF1ab/nsp8143D143GD4085GnonsyngATgGG149720.0013360112518-12520
ORF1ab/nsp8143D143DD4085DsyngaTgaC247247112518-12520
ORF1ab/nsp8143D143ND4085NnonsynGatAat9090112518-12520
ORF1ab/nsp8143D143VD4085VnonsyngAtgTt70680.97142912518-12520
ORF1ab/nsp8143D143VD4085VnonsyngATgTA7010.014285712518-12520
ORF1ab/nsp8143D143VD4085VnonsyngATgTG7010.014285712518-12520
ORF1ab/nsp8143D143YD4085YnonsynGatTat4949112518-12520
ORF1ab/nsp8143D143AD4085AnonsyngAtgCt4141112518-12520
ORF1ab/nsp8143D143delD4085deldelGAT---4040112518-12520
ORF1ab/nsp8143D143ED4085EnonsyngaTgaA1680.512518-12520
ORF1ab/nsp8143D143ED4085EnonsyngaTgaG1680.512518-12520
ORF1ab/nsp8143D143HD4085HnonsynGatCat66112518-12520
ORF1ab/nsp8143D143PD4085PnonsynGAtCCt22112518-12520
ORF1ab/nsp8143D143del1D4085del1delGaTAa-22112518-12520
ORF1ab/nsp8143D143TD4085TnonsynGATACA11112518-12520
ORF1ab/nsp8143D143del2D4085del2delGAt--t11112518-12520

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp8143D143GgAtgGt14951497All0.000286
ORF1ab/nsp8143D143GgATgGG21497All0
ORF1ab/nsp8143D143GgAtgGt980980B.1.1.3160.906568
ORF1ab/nsp8143D143DgaTgaC247247All0.000047
ORF1ab/nsp8143D143DgaTgaC101101B.1.1.2840.010847
ORF1ab/nsp8143D143NGatAat9090All0.000017
ORF1ab/nsp8143D143GgAtgGt8787AY.440.00053
ORF1ab/nsp8143D143GgAtgGt7979AY.40.000123
ORF1ab/nsp8143D143VgAtgTt6870All0.000013
ORF1ab/nsp8143D143VgATgTA170All0
ORF1ab/nsp8143D143VgATgTG170All0
ORF1ab/nsp8143D143GgAtgGt6868R.20.985507
ORF1ab/nsp8143D143YGatTat4949All0.000009
ORF1ab/nsp8143D143VgAtgTt4545AY.40.00007
ORF1ab/nsp8143D143GgAtgGt4444B.10.000403
ORF1ab/nsp8143D143AgAtgCt4141All0.000008
ORF1ab/nsp8143D143delGAT---4040All0.000008
ORF1ab/nsp8143D143GgAtgGt3131B.1.10.000562
ORF1ab/nsp8143D143NGatAat2828AY.40.000044
ORF1ab/nsp8143D143GgAtgGt2424B.1.3780.164384
ORF1ab/nsp8143D143GgAtgGt2424B.1.4270.001212
ORF1ab/nsp8143D143GgAtgGt2323B.1.1.70.000021
ORF1ab/nsp8143D143GgAtgGt2121B.1.617.20.000079
ORF1ab/nsp8143D143DgaTgaC2121P.10.000331
ORF1ab/nsp8143D143NGatAat2020AY.1170.00169
ORF1ab/nsp8143D143EgaTgaG816All0.000002
ORF1ab/nsp8143D143EgaTgaA816All0.000002
ORF1ab/nsp8143D143DgaTgaC1515B.1.1.70.000013
ORF1ab/nsp8143D143GgAtgGt1414B.1.1.2070.016548
ORF1ab/nsp8143D143DgaTgaC1212AY.1020.000318
ORF1ab/nsp8143D143NGatAat1212B.1.1.70.000011
ORF1ab/nsp8143D143delGAT---1111B.1.1.70.00001
ORF1ab/nsp8143D143DgaTgaC1111B.1.617.20.000041
ORF1ab/nsp8143D143YGatTat1010B.1.1.70.000009
ORF1ab/nsp8143D143GgAtgGt99AY.250.000054
ORF1ab/nsp8143D143GgAtgGt99B.1.20.000079
ORF1ab/nsp8143D143VgAtgTt88B.1.1770.000105
ORF1ab/nsp8143D143DgaTgaC77AY.40.000011
ORF1ab/nsp8143D143AgAtgCt77B.1.1.70.000006
ORF1ab/nsp8143D143AgAtgCt77B.1.1770.000092
ORF1ab/nsp8143D143VgAtgTt77B.1.20.000062
ORF1ab/nsp8143D143NGatAat77B.1.6230.003755
ORF1ab/nsp8143D143HGatCat66All0.000001
ORF1ab/nsp8143D143YGatTat66AY.1030.000037
ORF1ab/nsp8143D143DgaTgaC66AY.1200.000223
ORF1ab/nsp8143D143AgAtgCt66AY.290.000095
ORF1ab/nsp8143D143YGatTat66AY.40.000009
ORF1ab/nsp8143D143AgAtgCt66AY.40.000009
ORF1ab/nsp8143D143GgAtgGt66AY.430.000027
ORF1ab/nsp8143D143DgaTgaC66B.1.3510.000178
ORF1ab/nsp8143D143GgAtgGt55AY.1130.000712
ORF1ab/nsp8143D143GgAtgGt55AY.46.60.000361
ORF1ab/nsp8143D143NGatAat55B.1.1770.000066
ORF1ab/nsp8143D143EgaTgaG55B.1.4270.000252
ORF1ab/nsp8143D143DgaTgaC44AY.200.000155
ORF1ab/nsp8143D143DgaTgaC44AY.250.000024
ORF1ab/nsp8143D143YGatTat44AY.290.000063
ORF1ab/nsp8143D143DgaTgaC44AY.290.000063
ORF1ab/nsp8143D143delGAT---44AY.430.000018
ORF1ab/nsp8143D143YGatTat44AY.440.000024
ORF1ab/nsp8143D143DgaTgaC33AY.1000.000138
ORF1ab/nsp8143D143DgaTgaC33AY.390.000074
ORF1ab/nsp8143D143delGAT---33AY.40.000005
ORF1ab/nsp8143D143DgaTgaC33AY.470.000093
ORF1ab/nsp8143D143GgAtgGt33B.1.1.4820.069767
ORF1ab/nsp8143D143GgAtgGt33B.1.1.5190.000119
ORF1ab/nsp8143D143AgAtgCt33B.1.1310.026316
ORF1ab/nsp8143D143DgaTgaC33B.1.20.000026
ORF1ab/nsp8143D143GgAtgGt33B.1.5960.000261
ORF1ab/nsp8143D143YGatTat33B.1.617.20.000011
ORF1ab/nsp8143D143GgAtgGt33C.370.000348
ORF1ab/nsp8143D143GgAtgGt33P.10.000047
ORF1ab/nsp8143D143GgATgGG220.111111
ORF1ab/nsp8143D143delGAT---220.111111
ORF1ab/nsp8143D143del1GaTAa-220.111111
ORF1ab/nsp8143D143PGAtCCt220.111111
ORF1ab/nsp8143D143del1GaTAa-22All0
ORF1ab/nsp8143D143PGAtCCt22All0
ORF1ab/nsp8143D143DgaTgaC22AY.1030.000012
ORF1ab/nsp8143D143DgaTgaC22AY.1160.000574
ORF1ab/nsp8143D143GgAtgGt22AY.1200.000074
ORF1ab/nsp8143D143NGatAat22AY.250.000012
ORF1ab/nsp8143D143DgaTgaC22AY.30.00002
ORF1ab/nsp8143D143EgaTgaA22AY.30.00002
ORF1ab/nsp8143D143GgAtgGt22AY.340.000194
ORF1ab/nsp8143D143DgaTgaC22AY.340.000194
ORF1ab/nsp8143D143GgAtgGt22AY.390.000049
ORF1ab/nsp8143D143EgaTgaA12AY.40.000002
ORF1ab/nsp8143D143EgaTgaG12AY.40.000002
ORF1ab/nsp8143D143delGAT---22AY.4.50.000215
ORF1ab/nsp8143D143GgAtgGt22AY.420.00008
ORF1ab/nsp8143D143DgaTgaC22AY.440.000012
ORF1ab/nsp8143D143delGAT---22AY.750.000112
ORF1ab/nsp8143D143DgaTgaC22AY.75.10.000361
ORF1ab/nsp8143D143GgAtgGt22AY.920.000575
ORF1ab/nsp8143D143YGatTat22B.10.000018
ORF1ab/nsp8143D143DgaTgaC22B.10.000018
ORF1ab/nsp8143D143VgAtgTt12B.10.000009
ORF1ab/nsp8143D143VgATgTG12B.10.000009
ORF1ab/nsp8143D143DgaTgaC22B.1.10.000036
ORF1ab/nsp8143D143NGatAat22B.1.1.2220.000408
ORF1ab/nsp8143D143EgaTgaA22B.1.1.70.000002
ORF1ab/nsp8143D143VgAtgTt12B.1.1.70.000001
ORF1ab/nsp8143D143VgATgTA12B.1.1.70.000001
ORF1ab/nsp8143D143VgAtgTt22B.1.160.200.017857
ORF1ab/nsp8143D143DgaTgaC22B.1.2580.000133
ORF1ab/nsp8143D143GgAtgGt22B.1.360.000292
ORF1ab/nsp8143D143GgAtgGt22B.1.36.80.002
ORF1ab/nsp8143D143DgaTgaC22B.1.4280.002041
ORF1ab/nsp8143D143DgaTgaC22B.1.438.10.000215
ORF1ab/nsp8143D143DgaTgaC22B.1.5260.000047
ORF1ab/nsp8143D143HGatCat22P.10.000032
ORF1ab/nsp8143D143delGAT---11A0.000387
ORF1ab/nsp8143D143GgAtgGt11A0.000387
ORF1ab/nsp8143D143DgaTgaC11A.23.10.000704
ORF1ab/nsp8143D143YGatTat11AE.80.000489
ORF1ab/nsp8143D143del2GAt--t11All0
ORF1ab/nsp8143D143TGATACA11All0
ORF1ab/nsp8143D143YGatTat11AY.1000.000046
ORF1ab/nsp8143D143GgAtgGt11AY.1000.000046
ORF1ab/nsp8143D143NGatAat11AY.1020.000027
ORF1ab/nsp8143D143GgAtgGt11AY.1020.000027
ORF1ab/nsp8143D143AgAtgCt11AY.1030.000006
ORF1ab/nsp8143D143HGatCat11AY.1030.000006
ORF1ab/nsp8143D143GgAtgGt11AY.1030.000006
ORF1ab/nsp8143D143GgAtgGt11AY.1190.000035
ORF1ab/nsp8143D143YGatTat11AY.1190.000035
ORF1ab/nsp8143D143DgaTgaC11AY.1190.000035
ORF1ab/nsp8143D143YGatTat11AY.1210.000135
ORF1ab/nsp8143D143EgaTgaG11AY.130.000161
ORF1ab/nsp8143D143GgAtgGt11AY.140.000088
ORF1ab/nsp8143D143GgAtgGt11AY.200.000039
ORF1ab/nsp8143D143AgAtgCt11AY.200.000039
ORF1ab/nsp8143D143YGatTat11AY.230.00007
ORF1ab/nsp8143D143delGAT---11AY.250.000006
ORF1ab/nsp8143D143GgAtgGt11AY.270.000065
ORF1ab/nsp8143D143AgAtgCt11AY.30.00001
ORF1ab/nsp8143D143GgAtgGt11AY.30.00001
ORF1ab/nsp8143D143NGatAat11AY.330.000067
ORF1ab/nsp8143D143GgAtgGt11AY.39.10.00004
ORF1ab/nsp8143D143DgaTgaC11AY.39.10.00004
ORF1ab/nsp8143D143AgAtgCt11AY.4.2.10.000149
ORF1ab/nsp8143D143GgAtgGt11AY.4.40.000409
ORF1ab/nsp8143D143GgAtgGt11AY.4.50.000107
ORF1ab/nsp8143D143DgaTgaC11AY.410.000294
ORF1ab/nsp8143D143AgAtgCt11AY.430.000004
ORF1ab/nsp8143D143AgAtgCt11AY.440.000006
ORF1ab/nsp8143D143DgaTgaC11AY.450.000122
ORF1ab/nsp8143D143EgaTgaA11AY.460.000104
ORF1ab/nsp8143D143delGAT---11AY.460.000104
ORF1ab/nsp8143D143delGAT---11AY.46.20.000635
ORF1ab/nsp8143D143GgAtgGt11AY.470.000031
ORF1ab/nsp8143D143DgaTgaC11AY.50.000021
ORF1ab/nsp8143D143GgAtgGt11AY.50.000021
ORF1ab/nsp8143D143AgAtgCt11AY.540.000095
ORF1ab/nsp8143D143DgaTgaC11AY.550.000917
ORF1ab/nsp8143D143DgaTgaC11AY.610.000105
ORF1ab/nsp8143D143AgAtgCt11AY.690.000187
ORF1ab/nsp8143D143GgAtgGt11AY.75.10.00018
ORF1ab/nsp8143D143delGAT---11AY.80.000606
ORF1ab/nsp8143D143GgAtgGt11AY.840.000437
ORF1ab/nsp8143D143DgaTgaC11AY.9.10.000084
ORF1ab/nsp8143D143YGatTat11AY.9.20.000037
ORF1ab/nsp8143D143NGatAat11AY.950.000761
ORF1ab/nsp8143D143DgaTgaC11AY.970.001701
ORF1ab/nsp8143D143GgAtgGt11AY.980.000079
ORF1ab/nsp8143D143GgAtgGt11B0.000128
ORF1ab/nsp8143D143NGatAat11B.10.000009
ORF1ab/nsp8143D143delGAT---11B.10.000009
ORF1ab/nsp8143D143EgaTgaA11B.10.000009
ORF1ab/nsp8143D143HGatCat11B.10.000009
ORF1ab/nsp8143D143VgAtgTt11B.1.10.000018
ORF1ab/nsp8143D143NGatAat11B.1.10.000018
ORF1ab/nsp8143D143AgAtgCt11B.1.10.000018
ORF1ab/nsp8143D143GgAtgGt11B.1.1.2220.000204
ORF1ab/nsp8143D143YGatTat11B.1.1.250.000569
ORF1ab/nsp8143D143AgAtgCt11B.1.1.280.000311
ORF1ab/nsp8143D143delGAT---11B.1.1.280.000311
ORF1ab/nsp8143D143GgAtgGt11B.1.1.3400.045455
ORF1ab/nsp8143D143GgAtgGt11B.1.1.3550.015385
ORF1ab/nsp8143D143delGAT---11B.1.1.370.000193
ORF1ab/nsp8143D143GgAtgGt11B.1.1.4160.000905
ORF1ab/nsp8143D143DgaTgaC11B.1.1.4190.007407
ORF1ab/nsp8143D143delGAT---11B.1.1.4480.002033
ORF1ab/nsp8143D143DgaTgaC11B.1.1.4580.041667
ORF1ab/nsp8143D143GgAtgGt11B.1.1.4860.001577
ORF1ab/nsp8143D143del2GAt--t11B.1.1.70.000001
ORF1ab/nsp8143D143GgAtgGt11B.1.130.002375
ORF1ab/nsp8143D143DgaTgaC11B.1.1600.000031
ORF1ab/nsp8143D143GgAtgGt11B.1.1600.000031
ORF1ab/nsp8143D143YGatTat11B.1.1620.005025
ORF1ab/nsp8143D143delGAT---11B.1.1770.000013
ORF1ab/nsp8143D143DgaTgaC11B.1.1770.000013
ORF1ab/nsp8143D143HGatCat11B.1.1770.000013
ORF1ab/nsp8143D143YGatTat11B.1.1770.000013
ORF1ab/nsp8143D143GgAtgGt11B.1.177.100.000878
ORF1ab/nsp8143D143GgAtgGt11B.1.177.160.000664
ORF1ab/nsp8143D143GgAtgGt11B.1.177.600.000218
ORF1ab/nsp8143D143EgaTgaA11B.1.177.860.000183
ORF1ab/nsp8143D143delGAT---11B.1.177.90.001332
ORF1ab/nsp8143D143TGATACA11B.1.20.000009
ORF1ab/nsp8143D143NGatAat11B.1.20.000009
ORF1ab/nsp8143D143VgAtgTt11B.1.221.20.004016
ORF1ab/nsp8143D143NGatAat11B.1.2430.00007
ORF1ab/nsp8143D143GgAtgGt11B.1.2430.00007
ORF1ab/nsp8143D143DgaTgaC11B.1.2790.000514
ORF1ab/nsp8143D143EgaTgaG11B.1.3510.00003
ORF1ab/nsp8143D143YGatTat11B.1.351.20.000303
ORF1ab/nsp8143D143DgaTgaC11B.1.3620.001541
ORF1ab/nsp8143D143GgAtgGt11B.1.3670.000792
ORF1ab/nsp8143D143GgAtgGt11B.1.4290.000024
ORF1ab/nsp8143D143GgAtgGt11B.1.438.10.000107
ORF1ab/nsp8143D143YGatTat11B.1.466.20.000391
ORF1ab/nsp8143D143NGatAat11B.1.5060.02381
ORF1ab/nsp8143D143DgaTgaC11B.1.5250.000113
ORF1ab/nsp8143D143GgAtgGt11B.1.5740.002151
ORF1ab/nsp8143D143GgAtgGt11B.1.5880.00091
ORF1ab/nsp8143D143NGatAat11B.1.5960.000087
ORF1ab/nsp8143D143VgAtgTt11B.1.617.10.000129
ORF1ab/nsp8143D143AgAtgCt11B.1.617.10.000129
ORF1ab/nsp8143D143delGAT---11B.1.617.20.000004
ORF1ab/nsp8143D143AgAtgCt11B.1.617.20.000004
ORF1ab/nsp8143D143NGatAat11B.1.617.20.000004
ORF1ab/nsp8143D143VgAtgTt11B.1.617.20.000004
ORF1ab/nsp8143D143GgAtgGt11B.1.6210.000089
ORF1ab/nsp8143D143DgaTgaC11B.1.621.10.000506
ORF1ab/nsp8143D143GgAtgGt11B.1.6370.000073
ORF1ab/nsp8143D143YGatTat11B.1.6370.000073
ORF1ab/nsp8143D143NGatAat11B.1.930.000934
ORF1ab/nsp8143D143NGatAat11B.230.002924
ORF1ab/nsp8143D143YGatTat11B.30.000831
ORF1ab/nsp8143D143DgaTgaC11B.410.008
ORF1ab/nsp8143D143GgAtgGt11C.140.004329
ORF1ab/nsp8143D143delGAT---11C.360.000911
ORF1ab/nsp8143D143YGatTat11D.20.000075
ORF1ab/nsp8143D143HGatCat11D.20.000075
ORF1ab/nsp8143D143NGatAat11D.20.000075
ORF1ab/nsp8143D143delGAT---11N.40.004255
ORF1ab/nsp8143D143NGatAat11P.10.000016
ORF1ab/nsp8143D143DgaTgaC11P.1.170.000162
ORF1ab/nsp8143D143delGAT---11Q.10.000126
ORF1ab/nsp8143D143delGAT---11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.