CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp8 : CodonNum = 130

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp8130V130IV4072InonsynGttAtt14081408112479-12481
ORF1ab/nsp8130V130VV4072VsyngtTgtC99880.88888912479-12481
ORF1ab/nsp8130V130VV4072VsyngtTgtA99100.1010112479-12481
ORF1ab/nsp8130V130VV4072VsyngtTgtG9910.01010112479-12481
ORF1ab/nsp8130V130AV4072AnonsyngTtgCt6666112479-12481
ORF1ab/nsp8130V130delV4072deldelGTT---3030112479-12481
ORF1ab/nsp8130V130FV4072FnonsynGttTtt3030112479-12481
ORF1ab/nsp8130V130GV4072GnonsyngTtgGt540.812479-12481
ORF1ab/nsp8130V130GV4072GnonsyngTTgGA510.212479-12481
ORF1ab/nsp8130V130DV4072DnonsyngTtgAt33112479-12481
ORF1ab/nsp8130V130LV4072LnonsynGttCtt320.66666712479-12481
ORF1ab/nsp8130V130LV4072LnonsynGtTCtA310.33333312479-12481
ORF1ab/nsp8130V130CV4072CnonsynGTtTGt22112479-12481
ORF1ab/nsp8130V130del2V4072del2delgTTg--11112479-12481
ORF1ab/nsp8130V130del1V4072del1delGtt-tt11112479-12481
ORF1ab/nsp8130V130SV4072SnonsynGTTTCG11112479-12481
ORF1ab/nsp8130V130KV4072KnonsynGTTAAA11112479-12481

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp8130V130IGttAtt14081408All0.000269
ORF1ab/nsp8130V130IGttAtt794794AY.800.896163
ORF1ab/nsp8130V130IGttAtt289289AY.200.011232
ORF1ab/nsp8130V130IGttAtt120120B.1.1.70.000107
ORF1ab/nsp8130V130VgtTgtC8899All0.000017
ORF1ab/nsp8130V130VgtTgtA1099All0.000002
ORF1ab/nsp8130V130VgtTgtG199All0
ORF1ab/nsp8130V130AgTtgCt6666All0.000013
ORF1ab/nsp8130V130IGttAtt5050AY.1020.001326
ORF1ab/nsp8130V130FGttTtt3030All0.000006
ORF1ab/nsp8130V130delGTT---3030All0.000006
ORF1ab/nsp8130V130VgtTgtC1818AY.40.000028
ORF1ab/nsp8130V130FGttTtt1313AY.40.00002
ORF1ab/nsp8130V130IGttAtt1212AY.46.20.007624
ORF1ab/nsp8130V130IGttAtt1111AY.4.20.000239
ORF1ab/nsp8130V130AgTtgCt1111B.1.1.70.00001
ORF1ab/nsp8130V130delGTT---1111B.1.1.70.00001
ORF1ab/nsp8130V130VgtTgtC1111B.1.617.20.000041
ORF1ab/nsp8130V130IGttAtt1010AY.40.000016
ORF1ab/nsp8130V130VgtTgtC99AY.1030.000056
ORF1ab/nsp8130V130VgtTgtC79B.1.1.70.000006
ORF1ab/nsp8130V130VgtTgtA29B.1.1.70.000002
ORF1ab/nsp8130V130AgTtgCt88AY.430.000035
ORF1ab/nsp8130V130IGttAtt88B.10.000073
ORF1ab/nsp8130V130AgTtgCt88B.1.20.00007
ORF1ab/nsp8130V130IGttAtt88B.1.3510.000238
ORF1ab/nsp8130V130IGttAtt88B.1.5260.000188
ORF1ab/nsp8130V130IGttAtt77AY.116.10.00218
ORF1ab/nsp8130V130VgtTgtC77AY.1200.00026
ORF1ab/nsp8130V130IGttAtt77AY.440.000043
ORF1ab/nsp8130V130IGttAtt77Q.80.001154
ORF1ab/nsp8130V130IGttAtt66AY.30.00006
ORF1ab/nsp8130V130GgTtgGt45All0.000001
ORF1ab/nsp8130V130GgTTgGA15All0
ORF1ab/nsp8130V130AgTtgCt55AY.1180.000313
ORF1ab/nsp8130V130IGttAtt55AY.430.000022
ORF1ab/nsp8130V130FGttTtt55B.10.000046
ORF1ab/nsp8130V130VgtTgtC55B.1.1770.000066
ORF1ab/nsp8130V130AgTtgCt55B.1.1770.000066
ORF1ab/nsp8130V130IGttAtt55B.1.617.20.000019
ORF1ab/nsp8130V130IGttAtt44AY.1030.000025
ORF1ab/nsp8130V130IGttAtt44AY.230.000279
ORF1ab/nsp8130V130AgTtgCt44AY.40.000006
ORF1ab/nsp8130V130IGttAtt44B.1.1.2220.000816
ORF1ab/nsp8130V130DgTtgAt33All0.000001
ORF1ab/nsp8130V130LGttCtt23All0
ORF1ab/nsp8130V130LGtTCtA13All0
ORF1ab/nsp8130V130VgtTgtC33AY.1000.000138
ORF1ab/nsp8130V130VgtTgtC33AY.46.40.000494
ORF1ab/nsp8130V130VgtTgtC33B.10.000027
ORF1ab/nsp8130V130AgTtgCt33B.10.000027
ORF1ab/nsp8130V130VgtTgtC33B.1.1.1590.014019
ORF1ab/nsp8130V130IGttAtt33B.1.20.000026
ORF1ab/nsp8130V130AgTtgCt33B.1.2320.001612
ORF1ab/nsp8130V130CGTtTGt22All0
ORF1ab/nsp8130V130IGttAtt22AY.1180.000125
ORF1ab/nsp8130V130IGttAtt22AY.1190.000071
ORF1ab/nsp8130V130AgTtgCt22AY.250.000012
ORF1ab/nsp8130V130delGTT---22AY.250.000012
ORF1ab/nsp8130V130IGttAtt22AY.260.000057
ORF1ab/nsp8130V130IGttAtt22AY.290.000032
ORF1ab/nsp8130V130VgtTgtC22AY.390.000049
ORF1ab/nsp8130V130IGttAtt22AY.390.000049
ORF1ab/nsp8130V130delGTT---22AY.430.000009
ORF1ab/nsp8130V130IGttAtt22AY.470.000062
ORF1ab/nsp8130V130IGttAtt22AY.50.000041
ORF1ab/nsp8130V130delGTT---22AY.750.000112
ORF1ab/nsp8130V130LGttCtt22B.10.000018
ORF1ab/nsp8130V130VgtTgtA22B.1.1.4200.002012
ORF1ab/nsp8130V130AgTtgCt22B.1.1.4860.003155
ORF1ab/nsp8130V130DgTtgAt22B.1.1.70.000002
ORF1ab/nsp8130V130IGttAtt22B.1.1600.000062
ORF1ab/nsp8130V130AgTtgCt22B.1.2430.000139
ORF1ab/nsp8130V130IGttAtt22B.1.3910.002255
ORF1ab/nsp8130V130AgTtgCt22B.1.617.20.000008
ORF1ab/nsp8130V130AgTtgCt22B.1.6370.000146
ORF1ab/nsp8130V130VgtTgtC22P.10.000032
ORF1ab/nsp8130V130IGttAtt22P.10.000032
ORF1ab/nsp8130V130IGttAtt22P.30.00319
ORF1ab/nsp8130V130IGttAtt11A.220.066667
ORF1ab/nsp8130V130delGTT---11AD.20.000219
ORF1ab/nsp8130V130del2gTTg--11All0
ORF1ab/nsp8130V130KGTTAAA11All0
ORF1ab/nsp8130V130SGTTTCG11All0
ORF1ab/nsp8130V130del1Gtt-tt11All0
ORF1ab/nsp8130V130VgtTgtC11AP.10.001502
ORF1ab/nsp8130V130VgtTgtC11AY.1190.000035
ORF1ab/nsp8130V130SGTTTCG11AY.1190.000035
ORF1ab/nsp8130V130delGTT---11AY.1200.000037
ORF1ab/nsp8130V130IGttAtt11AY.240.000431
ORF1ab/nsp8130V130IGttAtt11AY.250.000006
ORF1ab/nsp8130V130VgtTgtC11AY.250.000006
ORF1ab/nsp8130V130FGttTtt11AY.30.00001
ORF1ab/nsp8130V130AgTtgCt11AY.350.000233
ORF1ab/nsp8130V130CGTtTGt11AY.40.000002
ORF1ab/nsp8130V130VgtTgtC11AY.4.20.000022
ORF1ab/nsp8130V130IGttAtt11AY.410.000294
ORF1ab/nsp8130V130VgtTgtA11AY.430.000004
ORF1ab/nsp8130V130VgtTgtC11AY.440.000006
ORF1ab/nsp8130V130AgTtgCt11AY.440.000006
ORF1ab/nsp8130V130delGTT---11AY.460.000104
ORF1ab/nsp8130V130IGttAtt11AY.46.60.000072
ORF1ab/nsp8130V130VgtTgtA11AY.470.000031
ORF1ab/nsp8130V130delGTT---11AY.50.000021
ORF1ab/nsp8130V130IGttAtt11AY.540.000095
ORF1ab/nsp8130V130IGttAtt11AY.550.000917
ORF1ab/nsp8130V130delGTT---11AY.80.000606
ORF1ab/nsp8130V130GgTTgGA11AY.850.000427
ORF1ab/nsp8130V130IGttAtt11AY.850.000427
ORF1ab/nsp8130V130VgtTgtA11AY.850.000427
ORF1ab/nsp8130V130LGtTCtA11AY.850.000427
ORF1ab/nsp8130V130VgtTgtA11AY.98.10.000048
ORF1ab/nsp8130V130FGttTtt11AY.98.10.000048
ORF1ab/nsp8130V130IGttAtt11AY.99.20.000092
ORF1ab/nsp8130V130del2gTTg--11B.10.000009
ORF1ab/nsp8130V130IGttAtt11B.1.10.000018
ORF1ab/nsp8130V130FGttTtt11B.1.10.000018
ORF1ab/nsp8130V130VgtTgtC11B.1.10.000018
ORF1ab/nsp8130V130delGTT---11B.1.1.1390.022727
ORF1ab/nsp8130V130VgtTgtC11B.1.1.2200.001859
ORF1ab/nsp8130V130delGTT---11B.1.1.280.000311
ORF1ab/nsp8130V130IGttAtt11B.1.1.2840.000107
ORF1ab/nsp8130V130IGttAtt11B.1.1.330.000421
ORF1ab/nsp8130V130delGTT---11B.1.1.4480.002033
ORF1ab/nsp8130V130AgTtgCt11B.1.1.4560.055556
ORF1ab/nsp8130V130KGTTAAA11B.1.1.5190.00004
ORF1ab/nsp8130V130DgTtgAt11B.1.1.5190.00004
ORF1ab/nsp8130V130del1Gtt-tt11B.1.1.70.000001
ORF1ab/nsp8130V130IGttAtt11B.1.1170.0125
ORF1ab/nsp8130V130FGttTtt11B.1.1770.000013
ORF1ab/nsp8130V130IGttAtt11B.1.1770.000013
ORF1ab/nsp8130V130VgtTgtC11B.1.177.380.010417
ORF1ab/nsp8130V130VgtTgtC11B.1.177.560.000668
ORF1ab/nsp8130V130AgTtgCt11B.1.177.830.001481
ORF1ab/nsp8130V130delGTT---11B.1.177.90.001332
ORF1ab/nsp8130V130FGttTtt11B.1.20.000009
ORF1ab/nsp8130V130delGTT---11B.1.20.000009
ORF1ab/nsp8130V130IGttAtt11B.1.2180.005155
ORF1ab/nsp8130V130IGttAtt11B.1.2210.000071
ORF1ab/nsp8130V130FGttTtt11B.1.2220.001692
ORF1ab/nsp8130V130IGttAtt11B.1.2390.001221
ORF1ab/nsp8130V130FGttTtt11B.1.2580.000067
ORF1ab/nsp8130V130GgTtgGt11B.1.258.30.001675
ORF1ab/nsp8130V130VgtTgtA11B.1.258.70.001912
ORF1ab/nsp8130V130VgtTgtG11B.1.3130.006579
ORF1ab/nsp8130V130GgTtgGt11B.1.3360.002439
ORF1ab/nsp8130V130CGTtTGt11B.1.3510.00003
ORF1ab/nsp8130V130FGttTtt11B.1.3510.00003
ORF1ab/nsp8130V130VgtTgtC11B.1.360.000146
ORF1ab/nsp8130V130GgTtgGt11B.1.360.000146
ORF1ab/nsp8130V130IGttAtt11B.1.36.180.00042
ORF1ab/nsp8130V130IGttAtt11B.1.4270.00005
ORF1ab/nsp8130V130AgTtgCt11B.1.4290.000024
ORF1ab/nsp8130V130IGttAtt11B.1.4290.000024
ORF1ab/nsp8130V130FGttTtt11B.1.438.10.000107
ORF1ab/nsp8130V130AgTtgCt11B.1.5750.000303
ORF1ab/nsp8130V130VgtTgtA11B.1.5770.000687
ORF1ab/nsp8130V130FGttTtt11B.1.5960.000087
ORF1ab/nsp8130V130AgTtgCt11B.1.617.10.000129
ORF1ab/nsp8130V130FGttTtt11B.1.617.20.000004
ORF1ab/nsp8130V130delGTT---11B.1.617.20.000004
ORF1ab/nsp8130V130VgtTgtC11B.1.619.10.000641
ORF1ab/nsp8130V130IGttAtt11B.1.6210.000089
ORF1ab/nsp8130V130VgtTgtC11B.1.6210.000089
ORF1ab/nsp8130V130FGttTtt11B.1.6270.00202
ORF1ab/nsp8130V130GgTtgGt11B.60.00091
ORF1ab/nsp8130V130delGTT---11C.360.000911
ORF1ab/nsp8130V130IGttAtt11C.36.3.10.002717
ORF1ab/nsp8130V130AgTtgCt11D.20.000075
ORF1ab/nsp8130V130VgtTgtC11D.20.000075
ORF1ab/nsp8130V130delGTT---11N.40.004255
ORF1ab/nsp8130V130AgTtgCt11P.10.000016
ORF1ab/nsp8130V130IGttAtt11P.20.000187
ORF1ab/nsp8130V130IGttAtt11Q.10.000126
ORF1ab/nsp8130V130VgtTgtC11Q.70.001111
ORF1ab/nsp8130V130VgtTgtC11U.20.008772

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.