CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp8 : CodonNum = 122

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp8122L122FL4064FnonsynCttTtt28272827112455-12457
ORF1ab/nsp8122L122IL4064InonsynCttAtt13601360112455-12457
ORF1ab/nsp8122L122LL4064LsynctTctC2341410.60256412455-12457
ORF1ab/nsp8122L122LL4064LsynctTctA234920.39316212455-12457
ORF1ab/nsp8122L122LL4064LsynctTctG23410.004273512455-12457
ORF1ab/nsp8122L122delL4064deldelCTT---1717112455-12457
ORF1ab/nsp8122L122PL4064PnonsyncTtcCt1212112455-12457
ORF1ab/nsp8122L122RL4064RnonsyncTtcGt22112455-12457
ORF1ab/nsp8122L122VL4064VnonsynCttGtt22112455-12457
ORF1ab/nsp8122L122SL4064SnonsynCTtTCt22112455-12457
ORF1ab/nsp8122L122HL4064HnonsyncTtcAt22112455-12457
ORF1ab/nsp8122L122del1L4064del1delCtt-tt11112455-12457

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp8122L122FCttTtt28272827All0.000541
ORF1ab/nsp8122L122FCttTtt24572457B.1.258.110.973841
ORF1ab/nsp8122L122ICttAtt13601360All0.00026
ORF1ab/nsp8122L122ICttAtt895895B.1.5680.994444
ORF1ab/nsp8122L122LctTctC141234All0.000027
ORF1ab/nsp8122L122LctTctA92234All0.000018
ORF1ab/nsp8122L122LctTctG1234All0
ORF1ab/nsp8122L122ICttAtt231231B.1.617.20.00087
ORF1ab/nsp8122L122FCttTtt114114B.1.1.70.000102
ORF1ab/nsp8122L122ICttAtt6363AY.430.000279
ORF1ab/nsp8122L122LctTctA2841B.1.1.70.000025
ORF1ab/nsp8122L122LctTctC1341B.1.1.70.000012
ORF1ab/nsp8122L122LctTctC4040AY.40.000062
ORF1ab/nsp8122L122ICttAtt3535B.10.000321
ORF1ab/nsp8122L122LctTctA3535B.1.5930.380435
ORF1ab/nsp8122L122FCttTtt3030AY.40.000047
ORF1ab/nsp8122L122ICttAtt2727AY.560.043339
ORF1ab/nsp8122L122ICttAtt2626AY.290.00041
ORF1ab/nsp8122L122FCttTtt2626B.1.1.5190.001032
ORF1ab/nsp8122L122delCTT---1717All0.000003
ORF1ab/nsp8122L122FCttTtt1717AY.1030.000106
ORF1ab/nsp8122L122LctTctC1717B.1.20.00015
ORF1ab/nsp8122L122FCttTtt1515P.10.000236
ORF1ab/nsp8122L122FCttTtt1414B.10.000128
ORF1ab/nsp8122L122FCttTtt1414B.1.3910.015784
ORF1ab/nsp8122L122PcTtcCt1212All0.000002
ORF1ab/nsp8122L122FCttTtt1212B.1.20.000106
ORF1ab/nsp8122L122ICttAtt1111B.1.1.70.00001
ORF1ab/nsp8122L122FCttTtt1010AY.430.000044
ORF1ab/nsp8122L122FCttTtt1010B.1.1770.000132
ORF1ab/nsp8122L122LctTctA99B.1.438.10.000965
ORF1ab/nsp8122L122LctTctC99P.10.000142
ORF1ab/nsp8122L122FCttTtt88AY.250.000048
ORF1ab/nsp8122L122LctTctC88AY.430.000035
ORF1ab/nsp8122L122FCttTtt88B.1.3460.010485
ORF1ab/nsp8122L122ICttAtt77AY.39.10.000277
ORF1ab/nsp8122L122LctTctC67AY.440.000037
ORF1ab/nsp8122L122LctTctG17AY.440.000006
ORF1ab/nsp8122L122FCttTtt77B.1.5260.000165
ORF1ab/nsp8122L122ICttAtt66AY.40.000009
ORF1ab/nsp8122L122LctTctA66B.1.4800.014925
ORF1ab/nsp8122L122ICttAtt66B.1.6120.015915
ORF1ab/nsp8122L122LctTctC55AY.470.000156
ORF1ab/nsp8122L122LctTctC55AY.530.001438
ORF1ab/nsp8122L122ICttAtt55B.1.1770.000066
ORF1ab/nsp8122L122LctTctC55B.1.258.170.00052
ORF1ab/nsp8122L122LctTctA55C.360.004554
ORF1ab/nsp8122L122ICttAtt44AY.420.000161
ORF1ab/nsp8122L122PcTtcCt44B.10.000037
ORF1ab/nsp8122L122LctTctC34B.1.10.000054
ORF1ab/nsp8122L122LctTctA14B.1.10.000018
ORF1ab/nsp8122L122LctTctA44B.1.1.500.002716
ORF1ab/nsp8122L122FCttTtt44B.1.1600.000125
ORF1ab/nsp8122L122FCttTtt44B.1.5250.000453
ORF1ab/nsp8122L122FCttTtt44B.1.617.20.000015
ORF1ab/nsp8122L122FCttTtt33AE.80.001467
ORF1ab/nsp8122L122LctTctC33AY.250.000018
ORF1ab/nsp8122L122LctTctC33AY.370.000948
ORF1ab/nsp8122L122ICttAtt33AY.390.000074
ORF1ab/nsp8122L122ICttAtt33AY.400.002893
ORF1ab/nsp8122L122FCttTtt33AY.440.000018
ORF1ab/nsp8122L122ICttAtt33AY.99.20.000276
ORF1ab/nsp8122L122FCttTtt33B.1.1.3170.001235
ORF1ab/nsp8122L122delCTT---33B.1.1.70.000003
ORF1ab/nsp8122L122delCTT---33B.1.1770.00004
ORF1ab/nsp8122L122LctTctC33B.1.5960.000261
ORF1ab/nsp8122L122LctTctC33B.1.617.20.000011
ORF1ab/nsp8122L122RcTtcGt22All0
ORF1ab/nsp8122L122SCTtTCt22All0
ORF1ab/nsp8122L122VCttGtt22All0
ORF1ab/nsp8122L122HcTtcAt22All0
ORF1ab/nsp8122L122LctTctC22AY.360.000296
ORF1ab/nsp8122L122FCttTtt22AY.390.000049
ORF1ab/nsp8122L122ICttAtt22AY.610.00021
ORF1ab/nsp8122L122delCTT---22AY.750.000112
ORF1ab/nsp8122L122FCttTtt22B.1.10.000036
ORF1ab/nsp8122L122PcTtcCt22B.1.10.000036
ORF1ab/nsp8122L122LctTctC22B.1.1.250.001137
ORF1ab/nsp8122L122FCttTtt22B.1.177.60.001953
ORF1ab/nsp8122L122FCttTtt22B.1.22.10.0625
ORF1ab/nsp8122L122LctTctC22B.1.2210.000142
ORF1ab/nsp8122L122FCttTtt22B.1.2410.001623
ORF1ab/nsp8122L122FCttTtt22B.1.2580.000133
ORF1ab/nsp8122L122ICttAtt22B.1.3510.000059
ORF1ab/nsp8122L122FCttTtt22B.1.3510.000059
ORF1ab/nsp8122L122FCttTtt22B.1.4290.000047
ORF1ab/nsp8122L122ICttAtt22B.1.5960.000174
ORF1ab/nsp8122L122FCttTtt22B.1.5970.009259
ORF1ab/nsp8122L122FCttTtt22C.10.004785
ORF1ab/nsp8122L122ICttAtt22P.1.10.000635
ORF1ab/nsp8122L122FCttTtt22P.1.100.000539
ORF1ab/nsp8122L122FCttTtt22Q.80.00033
ORF1ab/nsp8122L122ICttAtt11A0.000387
ORF1ab/nsp8122L122del1Ctt-tt11All0
ORF1ab/nsp8122L122FCttTtt11AY.1020.000027
ORF1ab/nsp8122L122ICttAtt11AY.1020.000027
ORF1ab/nsp8122L122LctTctC11AY.1030.000006
ORF1ab/nsp8122L122ICttAtt11AY.1140.000231
ORF1ab/nsp8122L122HcTtcAt11AY.1170.000085
ORF1ab/nsp8122L122LctTctA11AY.1200.000037
ORF1ab/nsp8122L122delCTT---11AY.1200.000037
ORF1ab/nsp8122L122FCttTtt11AY.1200.000037
ORF1ab/nsp8122L122ICttAtt11AY.16.10.00047
ORF1ab/nsp8122L122LctTctC11AY.200.000039
ORF1ab/nsp8122L122ICttAtt11AY.230.00007
ORF1ab/nsp8122L122LctTctC11AY.230.00007
ORF1ab/nsp8122L122FCttTtt11AY.230.00007
ORF1ab/nsp8122L122RcTtcGt11AY.240.000431
ORF1ab/nsp8122L122LctTctC11AY.240.000431
ORF1ab/nsp8122L122ICttAtt11AY.250.000006
ORF1ab/nsp8122L122delCTT---11AY.250.000006
ORF1ab/nsp8122L122ICttAtt11AY.260.000028
ORF1ab/nsp8122L122ICttAtt11AY.29.10.000221
ORF1ab/nsp8122L122FCttTtt11AY.29.10.000221
ORF1ab/nsp8122L122FCttTtt11AY.30.00001
ORF1ab/nsp8122L122FCttTtt11AY.3.10.000085
ORF1ab/nsp8122L122ICttAtt11AY.320.000532
ORF1ab/nsp8122L122PcTtcCt11AY.40.000002
ORF1ab/nsp8122L122ICttAtt11AY.4.10.000737
ORF1ab/nsp8122L122FCttTtt11AY.4.20.000022
ORF1ab/nsp8122L122ICttAtt11AY.4.50.000107
ORF1ab/nsp8122L122LctTctC11AY.400.000964
ORF1ab/nsp8122L122delCTT---11AY.440.000006
ORF1ab/nsp8122L122FCttTtt11AY.460.000104
ORF1ab/nsp8122L122ICttAtt11AY.46.20.000635
ORF1ab/nsp8122L122FCttTtt11AY.46.50.000198
ORF1ab/nsp8122L122ICttAtt11AY.50.000021
ORF1ab/nsp8122L122FCttTtt11AY.50.000021
ORF1ab/nsp8122L122ICttAtt11AY.520.000814
ORF1ab/nsp8122L122FCttTtt11AY.540.000095
ORF1ab/nsp8122L122ICttAtt11AY.540.000095
ORF1ab/nsp8122L122FCttTtt11AY.670.000464
ORF1ab/nsp8122L122FCttTtt11AY.750.000056
ORF1ab/nsp8122L122LctTctC11AY.750.000056
ORF1ab/nsp8122L122delCTT---11AY.80.000606
ORF1ab/nsp8122L122FCttTtt11AY.9.20.000037
ORF1ab/nsp8122L122ICttAtt11B0.000128
ORF1ab/nsp8122L122LctTctA11B.10.000009
ORF1ab/nsp8122L122ICttAtt11B.1.10.000018
ORF1ab/nsp8122L122FCttTtt11B.1.1.10.000327
ORF1ab/nsp8122L122FCttTtt11B.1.1.1300.015385
ORF1ab/nsp8122L122delCTT---11B.1.1.1390.022727
ORF1ab/nsp8122L122LctTctC11B.1.1.1760.000439
ORF1ab/nsp8122L122FCttTtt11B.1.1.2140.000055
ORF1ab/nsp8122L122FCttTtt11B.1.1.2220.000204
ORF1ab/nsp8122L122VCttGtt11B.1.1.250.000569
ORF1ab/nsp8122L122RcTtcGt11B.1.1.3000.010753
ORF1ab/nsp8122L122SCTtTCt11B.1.1.3060.000438
ORF1ab/nsp8122L122LctTctC11B.1.1.3720.000689
ORF1ab/nsp8122L122ICttAtt11B.1.1.4090.002833
ORF1ab/nsp8122L122delCTT---11B.1.1.4480.002033
ORF1ab/nsp8122L122ICttAtt11B.1.1.4870.005587
ORF1ab/nsp8122L122FCttTtt11B.1.1.720.030303
ORF1ab/nsp8122L122FCttTtt11B.1.1470.000756
ORF1ab/nsp8122L122PcTtcCt11B.1.1600.000031
ORF1ab/nsp8122L122FCttTtt11B.1.177.120.000152
ORF1ab/nsp8122L122FCttTtt11B.1.177.160.000664
ORF1ab/nsp8122L122FCttTtt11B.1.177.440.000519
ORF1ab/nsp8122L122delCTT---11B.1.177.90.001332
ORF1ab/nsp8122L122HcTtcAt11B.1.20.000009
ORF1ab/nsp8122L122ICttAtt11B.1.20.000009
ORF1ab/nsp8122L122ICttAtt11B.1.2120.016667
ORF1ab/nsp8122L122FCttTtt11B.1.2360.002053
ORF1ab/nsp8122L122ICttAtt11B.1.2430.00007
ORF1ab/nsp8122L122LctTctC11B.1.2580.000067
ORF1ab/nsp8122L122FCttTtt11B.1.2600.003344
ORF1ab/nsp8122L122ICttAtt11B.1.3010.005917
ORF1ab/nsp8122L122LctTctC11B.1.3510.00003
ORF1ab/nsp8122L122FCttTtt11B.1.351.20.000303
ORF1ab/nsp8122L122FCttTtt11B.1.36.10.00114
ORF1ab/nsp8122L122FCttTtt11B.1.36.380.001642
ORF1ab/nsp8122L122ICttAtt11B.1.3670.000792
ORF1ab/nsp8122L122LctTctA11B.1.4290.000024
ORF1ab/nsp8122L122ICttAtt11B.1.4290.000024
ORF1ab/nsp8122L122FCttTtt11B.1.466.20.000391
ORF1ab/nsp8122L122PcTtcCt11B.1.4680.005714
ORF1ab/nsp8122L122VCttGtt11B.1.4940.034483
ORF1ab/nsp8122L122LctTctA11B.1.5260.000024
ORF1ab/nsp8122L122FCttTtt11B.1.5610.000397
ORF1ab/nsp8122L122FCttTtt11B.1.5640.000426
ORF1ab/nsp8122L122ICttAtt11B.1.5750.000303
ORF1ab/nsp8122L122FCttTtt11B.1.5900.004545
ORF1ab/nsp8122L122FCttTtt11B.1.5950.000261
ORF1ab/nsp8122L122LctTctC11B.1.6090.000479
ORF1ab/nsp8122L122FCttTtt11B.1.6090.000479
ORF1ab/nsp8122L122SCTtTCt11B.1.617.20.000004
ORF1ab/nsp8122L122delCTT---11B.1.617.20.000004
ORF1ab/nsp8122L122FCttTtt11B.1.6210.000089
ORF1ab/nsp8122L122PcTtcCt11B.1.6210.000089
ORF1ab/nsp8122L122FCttTtt11B.280.003279
ORF1ab/nsp8122L122PcTtcCt11B.4.50.011905
ORF1ab/nsp8122L122FCttTtt11C.370.000116
ORF1ab/nsp8122L122delCTT---11N.40.004255
ORF1ab/nsp8122L122FCttTtt11P.1.120.000484
ORF1ab/nsp8122L122ICttAtt11P.1.140.000048
ORF1ab/nsp8122L122FCttTtt11P.1.170.000162
ORF1ab/nsp8122L122del1Ctt-tt11Q.80.000165
ORF1ab/nsp8122L122FCttTtt11R.10.00009
ORF1ab/nsp8122L122LctTctC11R.10.00009
ORF1ab/nsp8122L122PcTtcCt11S.10.00495

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.