CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp7 : Mut = D44D

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp744D44DD3903DsyngaTgaC19131913111972-11974

Details of the mutation D44D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp744D44DgaTgaC19131913All0.000366
ORF1ab/nsp744D44DgaTgaC431431B.1.1.70.000386
ORF1ab/nsp744D44DgaTgaC213213B.1.10.003864
ORF1ab/nsp744D44DgaTgaC206206B.1.258.140.201961
ORF1ab/nsp744D44DgaTgaC202202AY.250.001215
ORF1ab/nsp744D44DgaTgaC191191AY.440.001163
ORF1ab/nsp744D44DgaTgaC148148B.1.160.221
ORF1ab/nsp744D44DgaTgaC4646AY.130.007405
ORF1ab/nsp744D44DgaTgaC4141AY.1030.000255
ORF1ab/nsp744D44DgaTgaC3737B.1.617.20.000139
ORF1ab/nsp744D44DgaTgaC3434B.10.000311
ORF1ab/nsp744D44DgaTgaC3434B.1.1.4490.772727
ORF1ab/nsp744D44DgaTgaC2727AY.40.000042
ORF1ab/nsp744D44DgaTgaC2727P.10.000425
ORF1ab/nsp744D44DgaTgaC2222AY.260.000623
ORF1ab/nsp744D44DgaTgaC2020B.1.20.000176
ORF1ab/nsp744D44DgaTgaC1919AY.430.000084
ORF1ab/nsp744D44DgaTgaC1818AY.1200.000669
ORF1ab/nsp744D44DgaTgaC1717AY.4.10.012537
ORF1ab/nsp744D44DgaTgaC99B.1.1.370.001736
ORF1ab/nsp744D44DgaTgaC99B.1.3240.014446
ORF1ab/nsp744D44DgaTgaC88AY.50.000165
ORF1ab/nsp744D44DgaTgaC88B.1.1600.00025
ORF1ab/nsp744D44DgaTgaC77AY.200.000272
ORF1ab/nsp744D44DgaTgaC55AY.390.000124
ORF1ab/nsp744D44DgaTgaC55B.1.1770.000066
ORF1ab/nsp744D44DgaTgaC55B.1.258.30.008375
ORF1ab/nsp744D44DgaTgaC44AY.1190.000141
ORF1ab/nsp744D44DgaTgaC44AY.30.00004
ORF1ab/nsp744D44DgaTgaC44AY.460.000416
ORF1ab/nsp744D44DgaTgaC44B.1.4290.000094
ORF1ab/nsp744D44DgaTgaC33AY.1020.00008
ORF1ab/nsp744D44DgaTgaC33AY.1160.00086
ORF1ab/nsp744D44DgaTgaC33AY.750.000168
ORF1ab/nsp744D44DgaTgaC33B.1.1.5140.115385
ORF1ab/nsp744D44DgaTgaC33B.1.3510.000089
ORF1ab/nsp744D44DgaTgaC33B.1.4160.003807
ORF1ab/nsp744D44DgaTgaC33B.1.4270.000151
ORF1ab/nsp744D44DgaTgaC33B.1.9.40.018405
ORF1ab/nsp744D44DgaTgaC33C.1.20.012766
ORF1ab/nsp744D44DgaTgaC22AY.116.10.000623
ORF1ab/nsp744D44DgaTgaC22AY.270.000129
ORF1ab/nsp744D44DgaTgaC22AY.540.000191
ORF1ab/nsp744D44DgaTgaC22AY.60.000082
ORF1ab/nsp744D44DgaTgaC22AY.610.00021
ORF1ab/nsp744D44DgaTgaC22B.1.1.2200.003717
ORF1ab/nsp744D44DgaTgaC22B.1.1.3880.090909
ORF1ab/nsp744D44DgaTgaC22B.1.1.390.001019
ORF1ab/nsp744D44DgaTgaC22B.1.1.4090.005666
ORF1ab/nsp744D44DgaTgaC22B.1.1.530.027397
ORF1ab/nsp744D44DgaTgaC22B.1.177.190.002861
ORF1ab/nsp744D44DgaTgaC22B.1.177.40.000422
ORF1ab/nsp744D44DgaTgaC22B.1.177.730.001133
ORF1ab/nsp744D44DgaTgaC22B.1.2580.000133
ORF1ab/nsp744D44DgaTgaC22Q.50.033898
ORF1ab/nsp744D44DgaTgaC22Q.80.00033
ORF1ab/nsp744D44DgaTgaC11A.20.000662
ORF1ab/nsp744D44DgaTgaC11AY.1060.000335
ORF1ab/nsp744D44DgaTgaC11AY.1130.000142
ORF1ab/nsp744D44DgaTgaC11AY.16.10.00047
ORF1ab/nsp744D44DgaTgaC11AY.23.10.000417
ORF1ab/nsp744D44DgaTgaC11AY.4.20.000022
ORF1ab/nsp744D44DgaTgaC11AY.4.2.10.000149
ORF1ab/nsp744D44DgaTgaC11AY.630.000387
ORF1ab/nsp744D44DgaTgaC11AY.640.000595
ORF1ab/nsp744D44DgaTgaC11AY.840.000437
ORF1ab/nsp744D44DgaTgaC11AY.9.10.000084
ORF1ab/nsp744D44DgaTgaC11AY.900.000684
ORF1ab/nsp744D44DgaTgaC11AY.980.000079
ORF1ab/nsp744D44DgaTgaC11B.1.1.1340.011364
ORF1ab/nsp744D44DgaTgaC11B.1.1.2770.000759
ORF1ab/nsp744D44DgaTgaC11B.1.1.2820.011628
ORF1ab/nsp744D44DgaTgaC11B.1.1.2840.000107
ORF1ab/nsp744D44DgaTgaC11B.1.1.3390.010526
ORF1ab/nsp744D44DgaTgaC11B.1.1.3480.000796
ORF1ab/nsp744D44DgaTgaC11B.1.1.4190.007407
ORF1ab/nsp744D44DgaTgaC11B.1.1.4320.001266
ORF1ab/nsp744D44DgaTgaC11B.1.1.4380.05
ORF1ab/nsp744D44DgaTgaC11B.1.1.440.00241
ORF1ab/nsp744D44DgaTgaC11B.1.1.5190.00004
ORF1ab/nsp744D44DgaTgaC11B.1.1110.001175
ORF1ab/nsp744D44DgaTgaC11B.1.160.280.002924
ORF1ab/nsp744D44DgaTgaC11B.1.177.150.000631
ORF1ab/nsp744D44DgaTgaC11B.1.177.210.000076
ORF1ab/nsp744D44DgaTgaC11B.1.177.70.000165
ORF1ab/nsp744D44DgaTgaC11B.1.177.770.000726
ORF1ab/nsp744D44DgaTgaC11B.1.214.20.0006
ORF1ab/nsp744D44DgaTgaC11B.1.2320.000537
ORF1ab/nsp744D44DgaTgaC11B.1.2340.000132
ORF1ab/nsp744D44DgaTgaC11B.1.2430.00007
ORF1ab/nsp744D44DgaTgaC11B.1.3490.000715
ORF1ab/nsp744D44DgaTgaC11B.1.36.100.004785
ORF1ab/nsp744D44DgaTgaC11B.1.4990.00105
ORF1ab/nsp744D44DgaTgaC11B.1.5510.00129
ORF1ab/nsp744D44DgaTgaC11B.1.5750.000303
ORF1ab/nsp744D44DgaTgaC11B.1.5870.001898
ORF1ab/nsp744D44DgaTgaC11B.1.5960.000087
ORF1ab/nsp744D44DgaTgaC11B.1.6090.000479
ORF1ab/nsp744D44DgaTgaC11B.1.6280.000352
ORF1ab/nsp744D44DgaTgaC11B.1.780.008547
ORF1ab/nsp744D44DgaTgaC11B.40.002208
ORF1ab/nsp744D44DgaTgaC11D.20.000075
ORF1ab/nsp744D44DgaTgaC11P.1.120.000484
ORF1ab/nsp744D44DgaTgaC11P.1.160.000374
ORF1ab/nsp744D44DgaTgaC11P.1.70.000319

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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