CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp6 : Mut = Y153C

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp6153Y153CY3722CnonsyntAttGt27362736111429-11431

Details of the mutation Y153C within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp6153Y153CtAttGt27362736All0.000523
ORF1ab/nsp6153Y153CtAttGt925925B.1.1.2140.051298
ORF1ab/nsp6153Y153CtAttGt613613B.1.214.20.367506
ORF1ab/nsp6153Y153CtAttGt165165B.1.4270.008332
ORF1ab/nsp6153Y153CtAttGt112112B.1.214.30.8
ORF1ab/nsp6153Y153CtAttGt7272B.10.000659
ORF1ab/nsp6153Y153CtAttGt6565AY.40.000101
ORF1ab/nsp6153Y153CtAttGt5858B.1.20.000511
ORF1ab/nsp6153Y153CtAttGt5757B.1.6351
ORF1ab/nsp6153Y153CtAttGt4242B.1.1.2220.008568
ORF1ab/nsp6153Y153CtAttGt4141AY.440.00025
ORF1ab/nsp6153Y153CtAttGt3737B.1.617.20.000139
ORF1ab/nsp6153Y153CtAttGt3535AY.1030.000217
ORF1ab/nsp6153Y153CtAttGt3131B.1.360.004523
ORF1ab/nsp6153Y153CtAttGt2323B.1.10.000417
ORF1ab/nsp6153Y153CtAttGt2020AY.430.000089
ORF1ab/nsp6153Y153CtAttGt1919B.1.4290.000447
ORF1ab/nsp6153Y153CtAttGt1919C.350.014706
ORF1ab/nsp6153Y153CtAttGt1818AY.116.10.005606
ORF1ab/nsp6153Y153CtAttGt1818B.1.1.70.000016
ORF1ab/nsp6153Y153CtAttGt1818B.1.2100.03838
ORF1ab/nsp6153Y153CtAttGt1818B.1.36.80.018
ORF1ab/nsp6153Y153CtAttGt1818B.1.6330.75
ORF1ab/nsp6153Y153CtAttGt1616AY.29.10.003528
ORF1ab/nsp6153Y153CtAttGt1616AY.4.20.000347
ORF1ab/nsp6153Y153CtAttGt1515AY.1000.00069
ORF1ab/nsp6153Y153CtAttGt1515B.1.5960.001307
ORF1ab/nsp6153Y153CtAttGt1414B0.001789
ORF1ab/nsp6153Y153CtAttGt1111AY.290.000174
ORF1ab/nsp6153Y153CtAttGt1010AY.250.00006
ORF1ab/nsp6153Y153CtAttGt1010B.1.1.5190.000397
ORF1ab/nsp6153Y153CtAttGt1010B.1.4710.027322
ORF1ab/nsp6153Y153CtAttGt1010B.1.6230.005365
ORF1ab/nsp6153Y153CtAttGt99B.1.2140.032967
ORF1ab/nsp6153Y153CtAttGt99B.1.3980.026786
ORF1ab/nsp6153Y153CtAttGt88B.1.1.2160.007124
ORF1ab/nsp6153Y153CtAttGt88B.1.177.570.002248
ORF1ab/nsp6153Y153CtAttGt88B.1.5750.002427
ORF1ab/nsp6153Y153CtAttGt77AY.260.000198
ORF1ab/nsp6153Y153CtAttGt77B.1.1770.000092
ORF1ab/nsp6153Y153CtAttGt66AY.200.000233
ORF1ab/nsp6153Y153CtAttGt66AY.390.000148
ORF1ab/nsp6153Y153CtAttGt66B.1.5950.001566
ORF1ab/nsp6153Y153CtAttGt55B.1.177.810.000947
ORF1ab/nsp6153Y153CtAttGt55B.1.214.10.1
ORF1ab/nsp6153Y153CtAttGt55B.1.3670.003962
ORF1ab/nsp6153Y153CtAttGt44B.1.1.3100.060606
ORF1ab/nsp6153Y153CtAttGt44B.1.177.440.002076
ORF1ab/nsp6153Y153CtAttGt44B.1.2580.000266
ORF1ab/nsp6153Y153CtAttGt44P.10.000063
ORF1ab/nsp6153Y153CtAttGt33AY.1190.000106
ORF1ab/nsp6153Y153CtAttGt33AY.470.000093
ORF1ab/nsp6153Y153CtAttGt33AY.50.000062
ORF1ab/nsp6153Y153CtAttGt33B.1.1.570.034483
ORF1ab/nsp6153Y153CtAttGt220.111111
ORF1ab/nsp6153Y153CtAttGt22AY.1060.00067
ORF1ab/nsp6153Y153CtAttGt22AY.1110.000366
ORF1ab/nsp6153Y153CtAttGt22AY.30.00002
ORF1ab/nsp6153Y153CtAttGt22AY.340.000194
ORF1ab/nsp6153Y153CtAttGt22AY.360.000296
ORF1ab/nsp6153Y153CtAttGt22AY.46.40.000329
ORF1ab/nsp6153Y153CtAttGt22B.1.1.150.027027
ORF1ab/nsp6153Y153CtAttGt22B.1.1600.000062
ORF1ab/nsp6153Y153CtAttGt22B.1.177.350.001382
ORF1ab/nsp6153Y153CtAttGt22B.1.3510.000059
ORF1ab/nsp6153Y153CtAttGt22B.1.36.290.001035
ORF1ab/nsp6153Y153CtAttGt22B.1.4590.008163
ORF1ab/nsp6153Y153CtAttGt22B.1.5410.00885
ORF1ab/nsp6153Y153CtAttGt22D.20.00015
ORF1ab/nsp6153Y153CtAttGt11A.50.001923
ORF1ab/nsp6153Y153CtAttGt11AY.1020.000027
ORF1ab/nsp6153Y153CtAttGt11AY.1140.000231
ORF1ab/nsp6153Y153CtAttGt11AY.1160.000287
ORF1ab/nsp6153Y153CtAttGt11AY.160.00038
ORF1ab/nsp6153Y153CtAttGt11AY.230.00007
ORF1ab/nsp6153Y153CtAttGt11AY.330.000067
ORF1ab/nsp6153Y153CtAttGt11AY.5.40.000277
ORF1ab/nsp6153Y153CtAttGt11AY.750.000056
ORF1ab/nsp6153Y153CtAttGt11AY.780.001541
ORF1ab/nsp6153Y153CtAttGt11AY.830.001724
ORF1ab/nsp6153Y153CtAttGt11AY.90.000068
ORF1ab/nsp6153Y153CtAttGt11AY.980.000079
ORF1ab/nsp6153Y153CtAttGt11AY.98.10.000048
ORF1ab/nsp6153Y153CtAttGt11AY.990.001049
ORF1ab/nsp6153Y153CtAttGt11B.1.1.1760.000439
ORF1ab/nsp6153Y153CtAttGt11B.1.1.280.000311
ORF1ab/nsp6153Y153CtAttGt11B.1.1.3060.000438
ORF1ab/nsp6153Y153CtAttGt11B.1.1.4340.000349
ORF1ab/nsp6153Y153CtAttGt11B.1.1.4580.041667
ORF1ab/nsp6153Y153CtAttGt11B.1.1.5150.02
ORF1ab/nsp6153Y153CtAttGt11B.1.1.700.000341
ORF1ab/nsp6153Y153CtAttGt11B.1.1.830.00271
ORF1ab/nsp6153Y153CtAttGt11B.1.177.40.000211
ORF1ab/nsp6153Y153CtAttGt11B.1.177.500.004695
ORF1ab/nsp6153Y153CtAttGt11B.1.177.600.000218
ORF1ab/nsp6153Y153CtAttGt11B.1.1790.003759
ORF1ab/nsp6153Y153CtAttGt11B.1.2210.000071
ORF1ab/nsp6153Y153CtAttGt11B.1.2700.005618
ORF1ab/nsp6153Y153CtAttGt11B.1.3890.001002
ORF1ab/nsp6153Y153CtAttGt11B.1.4620.007246
ORF1ab/nsp6153Y153CtAttGt11B.1.5580.004566
ORF1ab/nsp6153Y153CtAttGt11B.1.6000.005848
ORF1ab/nsp6153Y153CtAttGt11B.1.6090.000479
ORF1ab/nsp6153Y153CtAttGt11B.30.000831
ORF1ab/nsp6153Y153CtAttGt11B.350.007812
ORF1ab/nsp6153Y153CtAttGt11B.60.00091
ORF1ab/nsp6153Y153CtAttGt11P.1.140.000048

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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