CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp6 : Mut = V91L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp691V91LV3660LnonsynGtgTtg324132330.99753211243-11245
ORF1ab/nsp691V91LV3660LnonsynGtgCtg324180.0024683711243-11245

Details of the mutation V91L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp691V91LGtgTtg32333241All0.000618
ORF1ab/nsp691V91LGtgCtg83241All0.000002
ORF1ab/nsp691V91LGtgTtg20362036AY.50.042042
ORF1ab/nsp691V91LGtgTtg185185B.1.617.20.000697
ORF1ab/nsp691V91LGtgTtg134134B.1.10.002431
ORF1ab/nsp691V91LGtgTtg116116AY.40.000181
ORF1ab/nsp691V91LGtgTtg9193B.1.1.70.000081
ORF1ab/nsp691V91LGtgCtg293B.1.1.70.000002
ORF1ab/nsp691V91LGtgTtg6767B.1.5260.001575
ORF1ab/nsp691V91LGtgTtg5555AY.200.002138
ORF1ab/nsp691V91LGtgTtg4646AY.430.000204
ORF1ab/nsp691V91LGtgTtg3636AY.1020.000955
ORF1ab/nsp691V91LGtgTtg3636B.1.1.2940.04557
ORF1ab/nsp691V91LGtgTtg2929B.10.000266
ORF1ab/nsp691V91LGtgTtg2525B.1.4070.892857
ORF1ab/nsp691V91LGtgTtg2121AY.740.002429
ORF1ab/nsp691V91LGtgTtg1717AY.250.000102
ORF1ab/nsp691V91LGtgTtg1617B.1.20.000141
ORF1ab/nsp691V91LGtgCtg117B.1.20.000009
ORF1ab/nsp691V91LGtgTtg1515B.1.1600.000468
ORF1ab/nsp691V91LGtgTtg1515B.1.2430.001044
ORF1ab/nsp691V91LGtgTtg1314B.1.1770.000171
ORF1ab/nsp691V91LGtgCtg114B.1.1770.000013
ORF1ab/nsp691V91LGtgTtg1212AY.440.000073
ORF1ab/nsp691V91LGtgTtg1212AY.470.000373
ORF1ab/nsp691V91LGtgTtg1212B.1.110.30.008621
ORF1ab/nsp691V91LGtgTtg1212B.1.4290.000282
ORF1ab/nsp691V91LGtgTtg99AY.1030.000056
ORF1ab/nsp691V91LGtgTtg99AY.1170.000761
ORF1ab/nsp691V91LGtgTtg99AY.130.001449
ORF1ab/nsp691V91LGtgTtg88P.10.000126
ORF1ab/nsp691V91LGtgTtg77AY.1190.000247
ORF1ab/nsp691V91LGtgTtg77AY.290.00011
ORF1ab/nsp691V91LGtgTtg77AY.30.00007
ORF1ab/nsp691V91LGtgTtg77AY.390.000173
ORF1ab/nsp691V91LGtgTtg77B.1.360.001021
ORF1ab/nsp691V91LGtgTtg77B.1.6210.00062
ORF1ab/nsp691V91LGtgTtg66AY.46.60.000433
ORF1ab/nsp691V91LGtgTtg66AY.5.30.002024
ORF1ab/nsp691V91LGtgTtg56B.1.2320.002687
ORF1ab/nsp691V91LGtgCtg16B.1.2320.000537
ORF1ab/nsp691V91LGtgTtg66B.1.4660.139535
ORF1ab/nsp691V91LGtgTtg55A.2.50.002495
ORF1ab/nsp691V91LGtgTtg55AY.140.00044
ORF1ab/nsp691V91LGtgTtg55AY.230.000349
ORF1ab/nsp691V91LGtgTtg55R.10.00045
ORF1ab/nsp691V91LGtgTtg44AY.4.20.000087
ORF1ab/nsp691V91LGtgTtg44AY.98.10.000194
ORF1ab/nsp691V91LGtgTtg33AY.270.000194
ORF1ab/nsp691V91LGtgTtg33AY.60.000123
ORF1ab/nsp691V91LGtgTtg33AY.680.000821
ORF1ab/nsp691V91LGtgTtg33B.1.5960.000261
ORF1ab/nsp691V91LGtgTtg22AY.1000.000092
ORF1ab/nsp691V91LGtgTtg22AY.1200.000074
ORF1ab/nsp691V91LGtgTtg22AY.260.000057
ORF1ab/nsp691V91LGtgTtg22AY.34.10.00102
ORF1ab/nsp691V91LGtgTtg22AY.460.000208
ORF1ab/nsp691V91LGtgTtg22AY.46.20.001271
ORF1ab/nsp691V91LGtgTtg22AY.46.40.000329
ORF1ab/nsp691V91LGtgTtg22AY.550.001835
ORF1ab/nsp691V91LGtgTtg22AY.590.001059
ORF1ab/nsp691V91LGtgTtg22AY.610.00021
ORF1ab/nsp691V91LGtgTtg22AY.7.10.000225
ORF1ab/nsp691V91LGtgTtg22AY.750.000112
ORF1ab/nsp691V91LGtgTtg22B.1.1.2220.000408
ORF1ab/nsp691V91LGtgTtg22B.1.1.3060.000877
ORF1ab/nsp691V91LGtgTtg22B.1.1.5190.000079
ORF1ab/nsp691V91LGtgTtg22B.1.177.560.001335
ORF1ab/nsp691V91LGtgTtg22B.1.3510.000059
ORF1ab/nsp691V91LGtgTtg22B.1.3800.013245
ORF1ab/nsp691V91LGtgCtg12D.20.000075
ORF1ab/nsp691V91LGtgTtg12D.20.000075
ORF1ab/nsp691V91LGtgTtg22Q.40.00091
ORF1ab/nsp691V91LGtgTtg11A.23.10.000704
ORF1ab/nsp691V91LGtgTtg11AY.1090.00074
ORF1ab/nsp691V91LGtgTtg11AY.1130.000142
ORF1ab/nsp691V91LGtgTtg11AY.1140.000231
ORF1ab/nsp691V91LGtgTtg11AY.120.10.000321
ORF1ab/nsp691V91LGtgTtg11AY.160.00038
ORF1ab/nsp691V91LGtgTtg11AY.240.000431
ORF1ab/nsp691V91LGtgTtg11AY.300.000396
ORF1ab/nsp691V91LGtgTtg11AY.320.000532
ORF1ab/nsp691V91LGtgTtg11AY.340.000097
ORF1ab/nsp691V91LGtgTtg11AY.420.00004
ORF1ab/nsp691V91LGtgTtg11AY.450.000122
ORF1ab/nsp691V91LGtgTtg11AY.46.30.000934
ORF1ab/nsp691V91LGtgTtg11AY.5.40.000277
ORF1ab/nsp691V91LGtgTtg11AY.540.000095
ORF1ab/nsp691V91LGtgTtg11AY.640.000595
ORF1ab/nsp691V91LGtgTtg11AY.7.20.000559
ORF1ab/nsp691V91LGtgTtg11AY.75.10.00018
ORF1ab/nsp691V91LGtgTtg11AY.770.001127
ORF1ab/nsp691V91LGtgTtg11AY.890.004902
ORF1ab/nsp691V91LGtgTtg11AY.9.20.000037
ORF1ab/nsp691V91LGtgTtg11AY.910.00073
ORF1ab/nsp691V91LGtgTtg11AY.990.001049
ORF1ab/nsp691V91LGtgTtg11B0.000128
ORF1ab/nsp691V91LGtgTtg11B.1.1.2410.00207
ORF1ab/nsp691V91LGtgTtg11B.1.1.280.000311
ORF1ab/nsp691V91LGtgTtg11B.1.1.2840.000107
ORF1ab/nsp691V91LGtgTtg11B.1.1.3170.000412
ORF1ab/nsp691V91LGtgTtg11B.1.1.330.000421
ORF1ab/nsp691V91LGtgTtg11B.1.1.370.000193
ORF1ab/nsp691V91LGtgTtg11B.1.1.500.000679
ORF1ab/nsp691V91LGtgTtg11B.1.1.630.000386
ORF1ab/nsp691V91LGtgTtg11B.1.1240.007812
ORF1ab/nsp691V91LGtgTtg11B.1.160.330.004425
ORF1ab/nsp691V91LGtgTtg11B.1.177.600.000218
ORF1ab/nsp691V91LGtgTtg11B.1.177.750.001041
ORF1ab/nsp691V91LGtgTtg11B.1.177.810.000189
ORF1ab/nsp691V91LGtgCtg11B.1.177.830.001481
ORF1ab/nsp691V91LGtgTtg11B.1.2060.000816
ORF1ab/nsp691V91LGtgTtg11B.1.2210.000071
ORF1ab/nsp691V91LGtgTtg11B.1.2400.000216
ORF1ab/nsp691V91LGtgTtg11B.1.2580.000067
ORF1ab/nsp691V91LGtgTtg11B.1.36.290.000517
ORF1ab/nsp691V91LGtgTtg11B.1.36.310.001751
ORF1ab/nsp691V91LGtgCtg11B.1.3690.000285
ORF1ab/nsp691V91LGtgTtg11B.1.4270.00005
ORF1ab/nsp691V91LGtgTtg11B.1.4970.000315
ORF1ab/nsp691V91LGtgTtg11B.1.5250.000113
ORF1ab/nsp691V91LGtgTtg11B.1.5770.000687
ORF1ab/nsp691V91LGtgTtg11B.1.6090.000479
ORF1ab/nsp691V91LGtgTtg11B.400.000364
ORF1ab/nsp691V91LGtgTtg11P.1.140.000048
ORF1ab/nsp691V91LGtgTtg11P.1.90.004808
ORF1ab/nsp691V91LGtgTtg11P.20.000187
ORF1ab/nsp691V91LGtgTtg11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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