CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp6 : Mut = T77A

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp677T77AT3646AnonsynActGct242665624265630.99996211201-11203
ORF1ab/nsp677T77AT3646AnonsynAcTGcC2426656850.000035027611201-11203
ORF1ab/nsp677T77AT3646AnonsynAcTGcG242665660.0000024725411201-11203
ORF1ab/nsp677T77AT3646AnonsynAcTGcA242665620.00000082417911201-11203

Details of the mutation T77A within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp677T77AActGct24265632426656All0.464109
ORF1ab/nsp677T77AAcTGcC852426656All0.000016
ORF1ab/nsp677T77AAcTGcG62426656All0.000001
ORF1ab/nsp677T77AAcTGcA22426656All0
ORF1ab/nsp677T77AActGct642128642139AY.40.999423
ORF1ab/nsp677T77AAcTGcC11642139AY.40.000017
ORF1ab/nsp677T77AActGct225442225457B.1.617.20.848883
ORF1ab/nsp677T77AAcTGcC13225457B.1.617.20.000049
ORF1ab/nsp677T77AAcTGcA1225457B.1.617.20.000004
ORF1ab/nsp677T77AAcTGcG1225457B.1.617.20.000004
ORF1ab/nsp677T77AActGct215628215631AY.430.955332
ORF1ab/nsp677T77AAcTGcC3215631AY.430.000013
ORF1ab/nsp677T77AActGct165739165746AY.250.99689
ORF1ab/nsp677T77AAcTGcC4165746AY.250.000024
ORF1ab/nsp677T77AAcTGcG2165746AY.250.000012
ORF1ab/nsp677T77AAcTGcA1165746AY.250.000006
ORF1ab/nsp677T77AActGct162350162352AY.440.988186
ORF1ab/nsp677T77AAcTGcC2162352AY.440.000012
ORF1ab/nsp677T77AActGct160247160252AY.1030.994983
ORF1ab/nsp677T77AAcTGcC4160252AY.1030.000025
ORF1ab/nsp677T77AAcTGcG1160252AY.1030.000006
ORF1ab/nsp677T77AActGct100241100259AY.30.997036
ORF1ab/nsp677T77AAcTGcC18100259AY.30.000179
ORF1ab/nsp677T77AActGct6335563356AY.290.999338
ORF1ab/nsp677T77AAcTGcC163356AY.290.000016
ORF1ab/nsp677T77AActGct4834748347AY.50.998327
ORF1ab/nsp677T77AActGct4606646067AY.4.20.999111
ORF1ab/nsp677T77AAcTGcG146067AY.4.20.000022
ORF1ab/nsp677T77AActGct3991339913AY.390.98631
ORF1ab/nsp677T77AActGct3765937659AY.1020.998489
ORF1ab/nsp677T77AActGct2823028232AY.1190.996752
ORF1ab/nsp677T77AAcTGcC228232AY.1190.000071
ORF1ab/nsp677T77AActGct2686126861AY.1200.998662
ORF1ab/nsp677T77AActGct2554325544AY.200.992732
ORF1ab/nsp677T77AAcTGcC125544AY.200.000039
ORF1ab/nsp677T77AActGct2517025170AY.39.10.997069
ORF1ab/nsp677T77AActGct2474724747AY.420.995575
ORF1ab/nsp677T77AActGct2425624257AY.60.997615
ORF1ab/nsp677T77AAcTGcC124257AY.60.000041
ORF1ab/nsp677T77AActGct2164321643AY.1000.995721
ORF1ab/nsp677T77AActGct2054920555AY.98.10.995205
ORF1ab/nsp677T77AAcTGcC620555AY.98.10.000291
ORF1ab/nsp677T77AActGct1566215662AY.1180.981205
ORF1ab/nsp677T77AActGct1480814808AY.330.988848
ORF1ab/nsp677T77AActGct1397213982AY.230.974541
ORF1ab/nsp677T77AAcTGcC1013982AY.230.000697
ORF1ab/nsp677T77AActGct1370513705AY.46.60.989602
ORF1ab/nsp677T77AActGct1242112421AY.980.981199
ORF1ab/nsp677T77AActGct1169911700AY.3.10.997442
ORF1ab/nsp677T77AAcTGcC111700AY.3.10.000085
ORF1ab/nsp677T77AActGct1164111641AY.1170.983857
ORF1ab/nsp677T77AActGct1079810798AY.99.20.995116
ORF1ab/nsp677T77AActGct1028410284AY.340.997188
ORF1ab/nsp677T77AActGct94449444AY.460.982931
ORF1ab/nsp677T77AActGct92749274AY.4.50.996883
ORF1ab/nsp677T77AActGct88578857AY.7.10.998197
ORF1ab/nsp677T77AActGct79657965AY.450.969214
ORF1ab/nsp677T77AActGct76017602B.1.617.10.980268
ORF1ab/nsp677T77AAcTGcG17602B.1.617.10.000129
ORF1ab/nsp677T77AActGct72977298AY.1210.987415
ORF1ab/nsp677T77AAcTGcC17298AY.1210.000135
ORF1ab/nsp677T77AActGct69056905AY.1130.983198
ORF1ab/nsp677T77AActGct67086710AY.360.99422
ORF1ab/nsp677T77AAcTGcC26710AY.360.000296
ORF1ab/nsp677T77AActGct66686668AY.4.2.10.993445
ORF1ab/nsp677T77AActGct60676068AY.46.40.998026
ORF1ab/nsp677T77AAcTGcC16068AY.46.40.000165
ORF1ab/nsp677T77AActGct54525452AY.1110.998535
ORF1ab/nsp677T77AActGct50935093AY.70.998236
ORF1ab/nsp677T77AActGct50395039AY.46.50.999802
ORF1ab/nsp677T77AActGct45354535AY.29.11
ORF1ab/nsp677T77AActGct42994299AY.1140.993529
ORF1ab/nsp677T77AActGct42344234AY.1100.477124
ORF1ab/nsp677T77AActGct35513551AY.5.40.982568
ORF1ab/nsp677T77AActGct33813382AY.1160.969601
ORF1ab/nsp677T77AAcTGcC13382AY.1160.000287
ORF1ab/nsp677T77AActGct33773377AY.410.992651
ORF1ab/nsp677T77AActGct33543354AY.920.963516
ORF1ab/nsp677T77AActGct32063206AY.116.10.998443
ORF1ab/nsp677T77AActGct31633163AY.930.863736
ORF1ab/nsp677T77AActGct31103110AY.120.10.998395
ORF1ab/nsp677T77AActGct30583058AY.120.966498
ORF1ab/nsp677T77AActGct29402940AY.1060.984595
ORF1ab/nsp677T77AActGct29092909AY.5.30.981444
ORF1ab/nsp677T77AActGct25012501AY.10.989711
ORF1ab/nsp677T77AActGct24412441AY.4.40.998773
ORF1ab/nsp677T77AActGct23942394AY.23.10.999165
ORF1ab/nsp677T77AActGct23552355AY.9.20.086498
ORF1ab/nsp677T77AActGct23172317AY.850.989748
ORF1ab/nsp677T77AActGct22542254AY.940.997787
ORF1ab/nsp677T77AActGct22512251AY.840.984689
ORF1ab/nsp677T77AActGct21352135AY.1070.994874
ORF1ab/nsp677T77AActGct20232023AY.1010.992153
ORF1ab/nsp677T77AActGct20062006AY.120.2.10.999502
ORF1ab/nsp677T77AActGct19611961AY.34.11
ORF1ab/nsp677T77AActGct18231823AY.320.970714
ORF1ab/nsp677T77AActGct17791779AY.7.20.994966
ORF1ab/nsp677T77AActGct15061506AY.46.20.956798
ORF1ab/nsp677T77AActGct14651465AY.1050.942122
ORF1ab/nsp677T77AActGct14481448AY.900.991102
ORF1ab/nsp677T77AActGct13801380AY.39.1.11
ORF1ab/nsp677T77AActGct13561356AY.4.11
ORF1ab/nsp677T77AActGct13441346AY.910.981738
ORF1ab/nsp677T77AAcTGcC21346AY.910.001461
ORF1ab/nsp677T77AActGct13421342AY.1090.992604
ORF1ab/nsp677T77AActGct12751275AY.950.97032
ORF1ab/nsp677T77AActGct11811181AY.4.30.994108
ORF1ab/nsp677T77AActGct11751175AY.870.978351
ORF1ab/nsp677T77AActGct11641164AY.860.965975
ORF1ab/nsp677T77AActGct11061106B.10.01013
ORF1ab/nsp677T77AActGct11001100AY.880.972591
ORF1ab/nsp677T77AActGct10671067AY.46.30.996265
ORF1ab/nsp677T77AActGct959959AY.46.10.9846
ORF1ab/nsp677T77AActGct945945AY.470.029394
ORF1ab/nsp677T77AActGct930930AY.990.975866
ORF1ab/nsp677T77AActGct884884AY.800.997743
ORF1ab/nsp677T77AActGct865865AY.750.048459
ORF1ab/nsp677T77AActGct839839AY.770.945885
ORF1ab/nsp677T77AActGct819819AY.790.991525
ORF1ab/nsp677T77AActGct769769AY.1080.84785
ORF1ab/nsp677T77AActGct728728AY.820.987788
ORF1ab/nsp677T77AActGct717717AY.120.20.921594
ORF1ab/nsp677T77AActGct648648AY.39.20.998459
ORF1ab/nsp677T77AActGct638638AY.99.10.990683
ORF1ab/nsp677T77AActGct615615AY.730.409182
ORF1ab/nsp677T77AActGct611611AY.780.941448
ORF1ab/nsp677T77AActGct583583AY.970.991497
ORF1ab/nsp677T77AActGct576576AY.830.993103
ORF1ab/nsp677T77AActGct498498AY.1040.988095
ORF1ab/nsp677T77AActGct488488AY.810.972112
ORF1ab/nsp677T77AActGct475475AY.680.13003
ORF1ab/nsp677T77AActGct471471AY.220.985356
ORF1ab/nsp677T77AActGct470470AY.210.891841
ORF1ab/nsp677T77AActGct467467B0.059688
ORF1ab/nsp677T77AActGct464464AY.960.962656
ORF1ab/nsp677T77AActGct448448AY.550.411009
ORF1ab/nsp677T77AActGct405405AY.5.20.997537
ORF1ab/nsp677T77AActGct379379AY.740.04383
ORF1ab/nsp677T77AActGct324324AY.540.030892
ORF1ab/nsp677T77AActGct301301B.1.1.70.000269
ORF1ab/nsp677T77AActGct296296AY.590.15678
ORF1ab/nsp677T77AActGct286286AY.580.259528
ORF1ab/nsp677T77AActGct283283AY.190.322691
ORF1ab/nsp677T77AActGct265265AY.5.10.996241
ORF1ab/nsp677T77AActGct247247AY.260.006993
ORF1ab/nsp677T77AActGct246246AY.91.11
ORF1ab/nsp677T77AActGct233233AY.75.10.042012
ORF1ab/nsp677T77AActGct211212AY.530.060667
ORF1ab/nsp677T77AAcTGcC1212AY.530.000288
ORF1ab/nsp677T77AActGct204204AY.760.985507
ORF1ab/nsp677T77AActGct202202AY.520.164495
ORF1ab/nsp677T77AActGct201201AY.890.985294
ORF1ab/nsp677T77AActGct191191AY.1150.994792
ORF1ab/nsp677T77AActGct191191AY.620.083224
ORF1ab/nsp677T77AActGct183183B.1.177.70.030168
ORF1ab/nsp677T77AActGct182182AY.690.033974
ORF1ab/nsp677T77AActGct167167AY.640.099405
ORF1ab/nsp677T77AActGct160160AY.100.084791
ORF1ab/nsp677T77AActGct155155AY.670.071959
ORF1ab/nsp677T77AActGct150150AY.560.24077
ORF1ab/nsp677T77AActGct148148AY.370.046776
ORF1ab/nsp677T77AActGct141141AY.160.053531
ORF1ab/nsp677T77AActGct129129AY.630.049903
ORF1ab/nsp677T77AActGct114114C.380.919355
ORF1ab/nsp677T77AActGct109109AY.570.071522
ORF1ab/nsp677T77AActGct101101AY.350.023538
ORF1ab/nsp677T77AActGct9898AY.140.008625
ORF1ab/nsp677T77AActGct9898AY.400.094503
ORF1ab/nsp677T77AActGct9494AY.130.015132
ORF1ab/nsp677T77AActGct9393AY.480.043256
ORF1ab/nsp677T77AActGct8484AY.700.017515
ORF1ab/nsp677T77AActGct7979AY.650.042111
ORF1ab/nsp677T77AActGct7070AY.380.034948
ORF1ab/nsp677T77AActGct6969B.1.243.21
ORF1ab/nsp677T77AActGct6262AY.710.029454
ORF1ab/nsp677T77AActGct6161AY.600.057223
ORF1ab/nsp677T77AActGct5555B.1.10.000998
ORF1ab/nsp677T77AActGct5454AY.110.072289
ORF1ab/nsp677T77AActGct4141B.1.2140.150183
ORF1ab/nsp677T77AActGct3939AY.500.031175
ORF1ab/nsp677T77AActGct3838AY.490.121406
ORF1ab/nsp677T77AActGct3333AY.16.10.015508
ORF1ab/nsp677T77AActGct3232AY.610.003353
ORF1ab/nsp677T77AActGct3030AY.170.245902
ORF1ab/nsp677T77AActGct2929AY.300.011476
ORF1ab/nsp677T77AActGct2727AY.240.011638
ORF1ab/nsp677T77AActGct2525B.1.20.00022
ORF1ab/nsp677T77AActGct2323AY.510.020909
ORF1ab/nsp677T77AActGct2121AY.280.039698
ORF1ab/nsp677T77AActGct1919AY.90.001284
ORF1ab/nsp677T77AActGct1515AY.9.10.001256
ORF1ab/nsp677T77AActGct1515B.1.5760.013599
ORF1ab/nsp677T77AActGct1414AY.660.014973
ORF1ab/nsp677T77AActGct1414AY.80.008485
ORF1ab/nsp677T77AActGct1414B.1.1600.000437
ORF1ab/nsp677T77AActGct1212B.1.1.2940.01519
ORF1ab/nsp677T77AActGct1212B.1.6210.001062
ORF1ab/nsp677T77AActGct1212P.10.000189
ORF1ab/nsp677T77AActGct1111AY.720.014966
ORF1ab/nsp677T77AActGct1111AZ.20.009031
ORF1ab/nsp677T77AActGct1111B.1.1.5260.039007
ORF1ab/nsp677T77AActGct1111B.1.177.730.006229
ORF1ab/nsp677T77AActGct99A0.003483
ORF1ab/nsp677T77AActGct99B.1.1570.026866
ORF1ab/nsp677T77AActGct99B.1.6280.003171
ORF1ab/nsp677T77AActGct88B.1.3510.000238
ORF1ab/nsp677T77AActGct88B.1.6230.004292
ORF1ab/nsp677T77AActGct77AY.270.000453
ORF1ab/nsp677T77AActGct66A.2.50.002994
ORF1ab/nsp677T77AActGct66B.1.2210.000426
ORF1ab/nsp677T77AActGct66B.1.3150.036364
ORF1ab/nsp677T77AActGct66B.1.3490.004289
ORF1ab/nsp677T77AActGct66P.1.10.001906
ORF1ab/nsp677T77AActGct55AY.20.001781
ORF1ab/nsp677T77AActGct55B.1.1390.003666
ORF1ab/nsp677T77AActGct55B.1.3750.004098
ORF1ab/nsp677T77AActGct55B.1.5250.000566
ORF1ab/nsp677T77AActGct55B.1.6090.002397
ORF1ab/nsp677T77AActGct44B.1.1.5230.00625
ORF1ab/nsp677T77AActGct44B.1.1770.000053
ORF1ab/nsp677T77AActGct44B.1.2400.000862
ORF1ab/nsp677T77AActGct44B.1.2430.000278
ORF1ab/nsp677T77AActGct44B.1.3350.041237
ORF1ab/nsp677T77AActGct44B.1.351.30.003506
ORF1ab/nsp677T77AActGct44B.1.4740.007605
ORF1ab/nsp677T77AActGct44B.1.4850.059701
ORF1ab/nsp677T77AActGct44B.400.001457
ORF1ab/nsp677T77AActGct44Q.10.000505
ORF1ab/nsp677T77AActGct33B.1.3690.000856
ORF1ab/nsp677T77AActGct33B.1.4290.000071
ORF1ab/nsp677T77AActGct33B.1.6000.017544
ORF1ab/nsp677T77AActGct33C.260.022059
ORF1ab/nsp677T77AActGct33C.36.3.10.008152
ORF1ab/nsp677T77AActGct33C.370.000348
ORF1ab/nsp677T77AActGct220.111111
ORF1ab/nsp677T77AActGct22AU.20.004843
ORF1ab/nsp677T77AActGct22AU.30.004219
ORF1ab/nsp677T77AActGct22AY.150.004444
ORF1ab/nsp677T77AActGct22AY.180.020202
ORF1ab/nsp677T77AActGct22B.1.1.280.000622
ORF1ab/nsp677T77AActGct22B.1.1.3060.000877
ORF1ab/nsp677T77AActGct22B.1.1.3260.003521
ORF1ab/nsp677T77AActGct22B.1.1.3720.001377
ORF1ab/nsp677T77AActGct22B.1.1430.042553
ORF1ab/nsp677T77AActGct22B.1.1580.047619
ORF1ab/nsp677T77AActGct22B.1.2600.006689
ORF1ab/nsp677T77AActGct22B.1.3250.013793
ORF1ab/nsp677T77AActGct22B.1.351.20.000605
ORF1ab/nsp677T77AActGct22B.1.351.50.001199
ORF1ab/nsp677T77AActGct22B.1.4270.000101
ORF1ab/nsp677T77AActGct22B.1.4330.00639
ORF1ab/nsp677T77AActGct22B.1.466.20.000782
ORF1ab/nsp677T77AActGct22B.1.4710.005464
ORF1ab/nsp677T77AActGct22B.1.5950.000522
ORF1ab/nsp677T77AActGct22B.1.6040.034483
ORF1ab/nsp677T77AActGct22B.1.6290.026667
ORF1ab/nsp677T77AActGct22B.550.0059
ORF1ab/nsp677T77AActGct22C.36.30.001134
ORF1ab/nsp677T77AActGct22P.1.100.000539
ORF1ab/nsp677T77AActGct22P.1.120.000968
ORF1ab/nsp677T77AActGct22Q.80.00033
ORF1ab/nsp677T77AActGct11A.10.000282
ORF1ab/nsp677T77AActGct11A.20.000662
ORF1ab/nsp677T77AActGct11A.2.5.20.001572
ORF1ab/nsp677T77AActGct11AY.310.018519
ORF1ab/nsp677T77AActGct11B.1.1.1480.008772
ORF1ab/nsp677T77AActGct11B.1.1.2100.005714
ORF1ab/nsp677T77AActGct11B.1.1.2690.001353
ORF1ab/nsp677T77AActGct11B.1.1.3010.001179
ORF1ab/nsp677T77AActGct11B.1.1.3120.001912
ORF1ab/nsp677T77AActGct11B.1.1.3170.000412
ORF1ab/nsp677T77AActGct11B.1.1.3420.0625
ORF1ab/nsp677T77AActGct11B.1.1.3490.010309
ORF1ab/nsp677T77AActGct11B.1.1.390.00051
ORF1ab/nsp677T77AActGct11B.1.1.4090.002833
ORF1ab/nsp677T77AActGct11B.1.1.4320.001266
ORF1ab/nsp677T77AActGct11B.1.1.4480.002033
ORF1ab/nsp677T77AActGct11B.1.1.5120.028571
ORF1ab/nsp677T77AActGct11B.1.110.30.000718
ORF1ab/nsp677T77AActGct11B.1.1310.008772
ORF1ab/nsp677T77AActGct11B.1.1420.002899
ORF1ab/nsp677T77AActGct11B.1.1700.00431
ORF1ab/nsp677T77AActGct11B.1.177.570.000281
ORF1ab/nsp677T77AActGct11B.1.177.630.002703
ORF1ab/nsp677T77AActGct11B.1.1790.003759
ORF1ab/nsp677T77AActGct11B.1.2080.04
ORF1ab/nsp677T77AActGct11B.1.2180.005155
ORF1ab/nsp677T77AActGct11B.1.2390.001221
ORF1ab/nsp677T77AActGct11B.1.2470.014925
ORF1ab/nsp677T77AActGct11B.1.3050.002151
ORF1ab/nsp677T77AActGct11B.1.3110.000275
ORF1ab/nsp677T77AActGct11B.1.3400.004292
ORF1ab/nsp677T77AActGct11B.1.36.290.000517
ORF1ab/nsp677T77AActGct11B.1.3620.001541
ORF1ab/nsp677T77AActGct11B.1.3660.004878
ORF1ab/nsp677T77AActGct11B.1.3780.006849
ORF1ab/nsp677T77AActGct11B.1.3800.006623
ORF1ab/nsp677T77AActGct11B.1.390.003906
ORF1ab/nsp677T77AActGct11B.1.3970.004854
ORF1ab/nsp677T77AActGct11B.1.4000.000429
ORF1ab/nsp677T77AActGct11B.1.400.10.015152
ORF1ab/nsp677T77AActGct11B.1.4320.011236
ORF1ab/nsp677T77AActGct11B.1.4360.001029
ORF1ab/nsp677T77AActGct11B.1.4560.003268
ORF1ab/nsp677T77AActGct11B.1.4590.004082
ORF1ab/nsp677T77AActGct11B.1.4620.007246
ORF1ab/nsp677T77AActGct11B.1.5260.000024
ORF1ab/nsp677T77AActGct11B.1.5300.007143
ORF1ab/nsp677T77AActGct11B.1.5370.02
ORF1ab/nsp677T77AActGct11B.1.5460.003704
ORF1ab/nsp677T77AActGct11B.1.5510.00129
ORF1ab/nsp677T77AActGct11B.1.5600.00463
ORF1ab/nsp677T77AActGct11B.1.5710.009709
ORF1ab/nsp677T77AActGct11B.1.5770.000687
ORF1ab/nsp677T77AActGct11B.1.5810.009434
ORF1ab/nsp677T77AActGct11B.1.5960.000087
ORF1ab/nsp677T77AActGct11B.1.5990.00365
ORF1ab/nsp677T77AActGct11B.1.6190.000871
ORF1ab/nsp677T77AActGct11B.1.6270.00202
ORF1ab/nsp677T77AActGct11B.1.6320.006711
ORF1ab/nsp677T77AActGct11B.1.700.02439
ORF1ab/nsp677T77AActGct11B.1.810.021277
ORF1ab/nsp677T77AActGct11N.40.004255
ORF1ab/nsp677T77AActGct11P.1.130.000898
ORF1ab/nsp677T77AActGct11P.1.170.000162
ORF1ab/nsp677T77AActGct11P.1.40.000977
ORF1ab/nsp677T77AActGct11P.1.70.000319
ORF1ab/nsp677T77AActGct11P.70.004367
ORF1ab/nsp677T77AActGct11Q.30.000145
ORF1ab/nsp677T77AActGct11Q.40.000455

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.