CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp6 : Mut = Q290H

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp6290Q290HQ3859HnonsyncaGcaT9129000.98684211840-11842
ORF1ab/nsp6290Q290HQ3859HnonsyncaGcaC912120.013157911840-11842

Details of the mutation Q290H within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp6290Q290HcaGcaT900912All0.000172
ORF1ab/nsp6290Q290HcaGcaC12912All0.000002
ORF1ab/nsp6290Q290HcaGcaT8080AY.40.000125
ORF1ab/nsp6290Q290HcaGcaT5860B.1.20.000511
ORF1ab/nsp6290Q290HcaGcaC260B.1.20.000018
ORF1ab/nsp6290Q290HcaGcaT5858B.1.617.20.000218
ORF1ab/nsp6290Q290HcaGcaT4848B.1.1.70.000043
ORF1ab/nsp6290Q290HcaGcaT4646AY.1020.00122
ORF1ab/nsp6290Q290HcaGcaT4040AY.370.012642
ORF1ab/nsp6290Q290HcaGcaT3939AY.470.001213
ORF1ab/nsp6290Q290HcaGcaT3538AY.430.000155
ORF1ab/nsp6290Q290HcaGcaC338AY.430.000013
ORF1ab/nsp6290Q290HcaGcaT3434AY.1030.000211
ORF1ab/nsp6290Q290HcaGcaT3434AY.440.000207
ORF1ab/nsp6290Q290HcaGcaT2424AY.50.000496
ORF1ab/nsp6290Q290HcaGcaT2323B.1.1600.000717
ORF1ab/nsp6290Q290HcaGcaT2222B.1.6210.001947
ORF1ab/nsp6290Q290HcaGcaT1919B.1.4290.000447
ORF1ab/nsp6290Q290HcaGcaT1818AY.1180.001128
ORF1ab/nsp6290Q290HcaGcaT1818AY.30.000179
ORF1ab/nsp6290Q290HcaGcaT1515B.1.1.130.535714
ORF1ab/nsp6290Q290HcaGcaT1515B.1.177.110.025467
ORF1ab/nsp6290Q290HcaGcaT1414B.1.1.4811
ORF1ab/nsp6290Q290HcaGcaT1313AY.420.000523
ORF1ab/nsp6290Q290HcaGcaT1111B.1.4270.000555
ORF1ab/nsp6290Q290HcaGcaT1010AY.250.00006
ORF1ab/nsp6290Q290HcaGcaT1010AY.390.000247
ORF1ab/nsp6290Q290HcaGcaT1010B.10.000092
ORF1ab/nsp6290Q290HcaGcaT1010B.1.1.1640.051546
ORF1ab/nsp6290Q290HcaGcaT1010B.1.177.750.010406
ORF1ab/nsp6290Q290HcaGcaT88AY.98.10.000387
ORF1ab/nsp6290Q290HcaGcaT88B.1.5870.01518
ORF1ab/nsp6290Q290HcaGcaT66AY.7.10.000676
ORF1ab/nsp6290Q290HcaGcaT66AY.880.005305
ORF1ab/nsp6290Q290HcaGcaT66B.1.5960.000523
ORF1ab/nsp6290Q290HcaGcaT55AY.4.20.000108
ORF1ab/nsp6290Q290HcaGcaT55AY.99.20.000461
ORF1ab/nsp6290Q290HcaGcaT55B.1.10.000091
ORF1ab/nsp6290Q290HcaGcaT55B.1.1770.000066
ORF1ab/nsp6290Q290HcaGcaC55B.1.177.570.001405
ORF1ab/nsp6290Q290HcaGcaT55B.1.360.00073
ORF1ab/nsp6290Q290HcaGcaT55R.10.00045
ORF1ab/nsp6290Q290HcaGcaT44AY.230.000279
ORF1ab/nsp6290Q290HcaGcaT44B.1.240.10.1
ORF1ab/nsp6290Q290HcaGcaT44B.1.2430.000278
ORF1ab/nsp6290Q290HcaGcaT34D.20.000225
ORF1ab/nsp6290Q290HcaGcaC14D.20.000075
ORF1ab/nsp6290Q290HcaGcaT44P.40.015209
ORF1ab/nsp6290Q290HcaGcaT33A.280.007937
ORF1ab/nsp6290Q290HcaGcaT33AY.39.20.004622
ORF1ab/nsp6290Q290HcaGcaT33B.1.1.10.00098
ORF1ab/nsp6290Q290HcaGcaT33B.1.2210.000213
ORF1ab/nsp6290Q290HcaGcaT33P.10.000047
ORF1ab/nsp6290Q290HcaGcaT22AY.1130.000285
ORF1ab/nsp6290Q290HcaGcaT22AY.1140.000462
ORF1ab/nsp6290Q290HcaGcaT22AY.1160.000574
ORF1ab/nsp6290Q290HcaGcaT22AY.1170.000169
ORF1ab/nsp6290Q290HcaGcaT22AY.1200.000074
ORF1ab/nsp6290Q290HcaGcaT22AY.120.10.000642
ORF1ab/nsp6290Q290HcaGcaT22AY.290.000032
ORF1ab/nsp6290Q290HcaGcaT22AY.3.10.000171
ORF1ab/nsp6290Q290HcaGcaT22AY.300.000791
ORF1ab/nsp6290Q290HcaGcaT22AY.330.000134
ORF1ab/nsp6290Q290HcaGcaT22AY.450.000243
ORF1ab/nsp6290Q290HcaGcaT22AY.5.40.000553
ORF1ab/nsp6290Q290HcaGcaT22AY.590.001059
ORF1ab/nsp6290Q290HcaGcaC12AY.740.000116
ORF1ab/nsp6290Q290HcaGcaT12AY.740.000116
ORF1ab/nsp6290Q290HcaGcaT22AY.75.10.000361
ORF1ab/nsp6290Q290HcaGcaT22AY.940.000885
ORF1ab/nsp6290Q290HcaGcaT22AY.980.000158
ORF1ab/nsp6290Q290HcaGcaT22B0.000256
ORF1ab/nsp6290Q290HcaGcaT22B.1.1.3170.000823
ORF1ab/nsp6290Q290HcaGcaT22B.1.1.370.000386
ORF1ab/nsp6290Q290HcaGcaT22B.1.1.5280.009615
ORF1ab/nsp6290Q290HcaGcaT22B.1.2580.000133
ORF1ab/nsp6290Q290HcaGcaT22Q.10.000253
ORF1ab/nsp6290Q290HcaGcaT11AY.1000.000046
ORF1ab/nsp6290Q290HcaGcaT11AY.1070.000466
ORF1ab/nsp6290Q290HcaGcaT11AY.1100.000113
ORF1ab/nsp6290Q290HcaGcaT11AY.1150.005208
ORF1ab/nsp6290Q290HcaGcaT11AY.1190.000035
ORF1ab/nsp6290Q290HcaGcaT11AY.1210.000135
ORF1ab/nsp6290Q290HcaGcaT11AY.200.000039
ORF1ab/nsp6290Q290HcaGcaT11AY.260.000028
ORF1ab/nsp6290Q290HcaGcaT11AY.270.000065
ORF1ab/nsp6290Q290HcaGcaT11AY.29.10.000221
ORF1ab/nsp6290Q290HcaGcaT11AY.320.000532
ORF1ab/nsp6290Q290HcaGcaT11AY.340.000097
ORF1ab/nsp6290Q290HcaGcaT11AY.360.000148
ORF1ab/nsp6290Q290HcaGcaT11AY.4.50.000107
ORF1ab/nsp6290Q290HcaGcaT11AY.460.000104
ORF1ab/nsp6290Q290HcaGcaT11AY.46.60.000072
ORF1ab/nsp6290Q290HcaGcaT11AY.610.000105
ORF1ab/nsp6290Q290HcaGcaT11AY.710.000475
ORF1ab/nsp6290Q290HcaGcaT11AY.870.000833
ORF1ab/nsp6290Q290HcaGcaT11AY.9.10.000084
ORF1ab/nsp6290Q290HcaGcaT11B.1.1.3180.000302
ORF1ab/nsp6290Q290HcaGcaT11B.1.1280.000635
ORF1ab/nsp6290Q290HcaGcaT11B.1.1570.002985
ORF1ab/nsp6290Q290HcaGcaT11B.1.160.260.002421
ORF1ab/nsp6290Q290HcaGcaT11B.1.177.160.000664
ORF1ab/nsp6290Q290HcaGcaT11B.1.177.440.000519
ORF1ab/nsp6290Q290HcaGcaT11B.1.177.630.002703
ORF1ab/nsp6290Q290HcaGcaT11B.1.258.100.011364
ORF1ab/nsp6290Q290HcaGcaT11B.1.3200.001245
ORF1ab/nsp6290Q290HcaGcaT11B.1.3240.001605
ORF1ab/nsp6290Q290HcaGcaT11B.1.351.50.0006
ORF1ab/nsp6290Q290HcaGcaT11B.1.36.290.000517
ORF1ab/nsp6290Q290HcaGcaT11B.1.3690.000285
ORF1ab/nsp6290Q290HcaGcaT11B.1.4530.003236
ORF1ab/nsp6290Q290HcaGcaT11B.1.5610.000397
ORF1ab/nsp6290Q290HcaGcaT11B.1.5640.000426
ORF1ab/nsp6290Q290HcaGcaT11B.1.6370.000073
ORF1ab/nsp6290Q290HcaGcaT11B.30.000831
ORF1ab/nsp6290Q290HcaGcaT11B.450.003831
ORF1ab/nsp6290Q290HcaGcaT11C.350.000774
ORF1ab/nsp6290Q290HcaGcaT11N.50.001767
ORF1ab/nsp6290Q290HcaGcaT11P.20.000187
ORF1ab/nsp6290Q290HcaGcaT11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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