CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp6 : Mut = M143I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp6143M143IM3712InonsynatGatT701068690.97988611399-11401
ORF1ab/nsp6143M143IM3712InonsynatGatC7010760.010841711399-11401
ORF1ab/nsp6143M143IM3712InonsynatGatA7010650.0092724711399-11401

Details of the mutation M143I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp6143M143IatGatT68697010All0.001314
ORF1ab/nsp6143M143IatGatC767010All0.000015
ORF1ab/nsp6143M143IatGatA657010All0.000012
ORF1ab/nsp6143M143IatGatT30983108AY.40.004822
ORF1ab/nsp6143M143IatGatC83108AY.40.000012
ORF1ab/nsp6143M143IatGatA23108AY.40.000003
ORF1ab/nsp6143M143IatGatT23102310B.1.1.3110.827364
ORF1ab/nsp6143M143IatGatT698747B.1.1.70.000625
ORF1ab/nsp6143M143IatGatC37747B.1.1.70.000033
ORF1ab/nsp6143M143IatGatA12747B.1.1.70.000011
ORF1ab/nsp6143M143IatGatT121122B.1.3510.003597
ORF1ab/nsp6143M143IatGatA1122B.1.3510.00003
ORF1ab/nsp6143M143IatGatT5760B.1.617.20.000215
ORF1ab/nsp6143M143IatGatA360B.1.617.20.000011
ORF1ab/nsp6143M143IatGatT4750AY.430.000208
ORF1ab/nsp6143M143IatGatA350AY.430.000013
ORF1ab/nsp6143M143IatGatT3746AY.250.000223
ORF1ab/nsp6143M143IatGatC846AY.250.000048
ORF1ab/nsp6143M143IatGatA146AY.250.000006
ORF1ab/nsp6143M143IatGatT3636Q.10.004548
ORF1ab/nsp6143M143IatGatT2229B.10.000202
ORF1ab/nsp6143M143IatGatA629B.10.000055
ORF1ab/nsp6143M143IatGatC129B.10.000009
ORF1ab/nsp6143M143IatGatT2424AY.390.000593
ORF1ab/nsp6143M143IatGatT2024B.1.20.000176
ORF1ab/nsp6143M143IatGatC324B.1.20.000026
ORF1ab/nsp6143M143IatGatA124B.1.20.000009
ORF1ab/nsp6143M143IatGatT1924P.10.000299
ORF1ab/nsp6143M143IatGatC524P.10.000079
ORF1ab/nsp6143M143IatGatT1121B.1.1770.000145
ORF1ab/nsp6143M143IatGatC821B.1.1770.000105
ORF1ab/nsp6143M143IatGatA221B.1.1770.000026
ORF1ab/nsp6143M143IatGatT1919AY.30.000189
ORF1ab/nsp6143M143IatGatT1619AY.440.000097
ORF1ab/nsp6143M143IatGatA319AY.440.000018
ORF1ab/nsp6143M143IatGatT1819B.1.10.000327
ORF1ab/nsp6143M143IatGatA119B.1.10.000018
ORF1ab/nsp6143M143IatGatT1617AY.1190.000565
ORF1ab/nsp6143M143IatGatA117AY.1190.000035
ORF1ab/nsp6143M143IatGatT1717B.1.1600.00053
ORF1ab/nsp6143M143IatGatT1717B.1.177.350.011748
ORF1ab/nsp6143M143IatGatT1717P.1.140.000813
ORF1ab/nsp6143M143IatGatT1515AY.450.001825
ORF1ab/nsp6143M143IatGatT1313B.1.438.10.001394
ORF1ab/nsp6143M143IatGatT1212B.1.5250.001358
ORF1ab/nsp6143M143IatGatT1111AY.290.000174
ORF1ab/nsp6143M143IatGatA510AY.1030.000031
ORF1ab/nsp6143M143IatGatT510AY.1030.000031
ORF1ab/nsp6143M143IatGatT99AY.200.00035
ORF1ab/nsp6143M143IatGatT99B.1.6280.003171
ORF1ab/nsp6143M143IatGatT88AY.420.000322
ORF1ab/nsp6143M143IatGatT47AY.340.000388
ORF1ab/nsp6143M143IatGatA37AY.340.000291
ORF1ab/nsp6143M143IatGatT57AY.4.20.000108
ORF1ab/nsp6143M143IatGatA27AY.4.20.000043
ORF1ab/nsp6143M143IatGatT67AY.50.000124
ORF1ab/nsp6143M143IatGatA17AY.50.000021
ORF1ab/nsp6143M143IatGatT77B.1.5260.000165
ORF1ab/nsp6143M143IatGatT66B.1.1.3180.001811
ORF1ab/nsp6143M143IatGatT66B.1.1.5190.000238
ORF1ab/nsp6143M143IatGatT66B.1.5950.001566
ORF1ab/nsp6143M143IatGatT35AY.9.20.00011
ORF1ab/nsp6143M143IatGatC15AY.9.20.000037
ORF1ab/nsp6143M143IatGatA15AY.9.20.000037
ORF1ab/nsp6143M143IatGatT55B.1.4270.000252
ORF1ab/nsp6143M143IatGatT35C.36.30.001702
ORF1ab/nsp6143M143IatGatC25C.36.30.001134
ORF1ab/nsp6143M143IatGatT44A.270.006623
ORF1ab/nsp6143M143IatGatT44AY.1200.000149
ORF1ab/nsp6143M143IatGatT44AY.90.00027
ORF1ab/nsp6143M143IatGatT44B.1.1.2140.000222
ORF1ab/nsp6143M143IatGatT44B.1.1.2360.027586
ORF1ab/nsp6143M143IatGatT44B.1.177.330.006579
ORF1ab/nsp6143M143IatGatT44B.1.2210.000284
ORF1ab/nsp6143M143IatGatT34B.1.4290.000071
ORF1ab/nsp6143M143IatGatC14B.1.4290.000024
ORF1ab/nsp6143M143IatGatT44P.1.150.000929
ORF1ab/nsp6143M143IatGatT33AY.10.001187
ORF1ab/nsp6143M143IatGatT33AY.330.0002
ORF1ab/nsp6143M143IatGatT23AY.46.60.000144
ORF1ab/nsp6143M143IatGatA13AY.46.60.000072
ORF1ab/nsp6143M143IatGatA33AY.850.001282
ORF1ab/nsp6143M143IatGatT33B.1.1.540.009063
ORF1ab/nsp6143M143IatGatT220.111111
ORF1ab/nsp6143M143IatGatT22A.2.50.000998
ORF1ab/nsp6143M143IatGatT22A.23.10.001408
ORF1ab/nsp6143M143IatGatT22AY.1010.000981
ORF1ab/nsp6143M143IatGatT12AY.1130.000142
ORF1ab/nsp6143M143IatGatA12AY.1130.000142
ORF1ab/nsp6143M143IatGatA22AY.1180.000125
ORF1ab/nsp6143M143IatGatT22AY.260.000057
ORF1ab/nsp6143M143IatGatT22AY.4.2.10.000298
ORF1ab/nsp6143M143IatGatT12AY.470.000031
ORF1ab/nsp6143M143IatGatA12AY.470.000031
ORF1ab/nsp6143M143IatGatT22AY.510.001818
ORF1ab/nsp6143M143IatGatT22AY.60.000082
ORF1ab/nsp6143M143IatGatT22AZ.10.001735
ORF1ab/nsp6143M143IatGatT22B.1.1.4090.005666
ORF1ab/nsp6143M143IatGatT22B.1.177.210.000153
ORF1ab/nsp6143M143IatGatT22B.1.177.420.001789
ORF1ab/nsp6143M143IatGatT22B.1.3960.001411
ORF1ab/nsp6143M143IatGatT22B.1.5640.000852
ORF1ab/nsp6143M143IatGatT22B.1.5770.001375
ORF1ab/nsp6143M143IatGatA11A.50.001923
ORF1ab/nsp6143M143IatGatC11AY.1020.000027
ORF1ab/nsp6143M143IatGatT11AY.1160.000287
ORF1ab/nsp6143M143IatGatT11AY.140.000088
ORF1ab/nsp6143M143IatGatT11AY.160.00038
ORF1ab/nsp6143M143IatGatT11AY.190.00114
ORF1ab/nsp6143M143IatGatT11AY.23.10.000417
ORF1ab/nsp6143M143IatGatT11AY.270.000065
ORF1ab/nsp6143M143IatGatT11AY.34.10.00051
ORF1ab/nsp6143M143IatGatT11AY.360.000148
ORF1ab/nsp6143M143IatGatA11AY.380.000499
ORF1ab/nsp6143M143IatGatT11AY.39.10.00004
ORF1ab/nsp6143M143IatGatT11AY.4.50.000107
ORF1ab/nsp6143M143IatGatT11AY.460.000104
ORF1ab/nsp6143M143IatGatT11AY.540.000095
ORF1ab/nsp6143M143IatGatA11AY.590.00053
ORF1ab/nsp6143M143IatGatT11AY.7.20.000559
ORF1ab/nsp6143M143IatGatA11AY.840.000437
ORF1ab/nsp6143M143IatGatT11AY.980.000079
ORF1ab/nsp6143M143IatGatA11AY.990.001049
ORF1ab/nsp6143M143IatGatT11B.1.1.100.001115
ORF1ab/nsp6143M143IatGatT11B.1.1.2200.001859
ORF1ab/nsp6143M143IatGatA11B.1.1.2790.001121
ORF1ab/nsp6143M143IatGatC11B.1.1.2860.002899
ORF1ab/nsp6143M143IatGatT11B.1.1.2940.001266
ORF1ab/nsp6143M143IatGatT11B.1.1.3160.000925
ORF1ab/nsp6143M143IatGatT11B.1.1.3390.010526
ORF1ab/nsp6143M143IatGatT11B.1.1.3720.000689
ORF1ab/nsp6143M143IatGatT11B.1.1.3760.005952
ORF1ab/nsp6143M143IatGatT11B.1.1.3890.006061
ORF1ab/nsp6143M143IatGatT11B.1.1.700.000341
ORF1ab/nsp6143M143IatGatT11B.1.1700.00431
ORF1ab/nsp6143M143IatGatA11B.1.177.160.000664
ORF1ab/nsp6143M143IatGatT11B.1.177.170.000821
ORF1ab/nsp6143M143IatGatT11B.1.177.60.000977
ORF1ab/nsp6143M143IatGatT11B.1.177.80.000752
ORF1ab/nsp6143M143IatGatT11B.1.2340.000132
ORF1ab/nsp6143M143IatGatT11B.1.351.20.000303
ORF1ab/nsp6143M143IatGatT11B.1.36.170.000494
ORF1ab/nsp6143M143IatGatT11B.1.36.390.002217
ORF1ab/nsp6143M143IatGatT11B.1.3690.000285
ORF1ab/nsp6143M143IatGatA11B.1.617.10.000129
ORF1ab/nsp6143M143IatGatT11B.1.6210.000089
ORF1ab/nsp6143M143IatGatT11B.1.6230.000536
ORF1ab/nsp6143M143IatGatT11C.370.000116
ORF1ab/nsp6143M143IatGatA11D.20.000075
ORF1ab/nsp6143M143IatGatT11P.1.120.000484
ORF1ab/nsp6143M143IatGatT11P.1.20.001156
ORF1ab/nsp6143M143IatGatT11Q.20.000613

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.