CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp6 : Mut = K8N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp68K8NK3577NnonsynaaGaaT191118800.98377810994-10996
ORF1ab/nsp68K8NK3577NnonsynaaGaaC1911310.016221910994-10996

Details of the mutation K8N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp68K8NaaGaaT18801911All0.00036
ORF1ab/nsp68K8NaaGaaC311911All0.000006
ORF1ab/nsp68K8NaaGaaT840840B.1.177.100.737489
ORF1ab/nsp68K8NaaGaaT241241AY.250.00145
ORF1ab/nsp68K8NaaGaaT131131N.50.231449
ORF1ab/nsp68K8NaaGaaT102102B.1.177.860.018712
ORF1ab/nsp68K8NaaGaaT101101AY.290.001593
ORF1ab/nsp68K8NaaGaaT4545B.1.20.000396
ORF1ab/nsp68K8NaaGaaT4343B.1.617.20.000162
ORF1ab/nsp68K8NaaGaaT1527B.1.1.70.000013
ORF1ab/nsp68K8NaaGaaC1227B.1.1.70.000011
ORF1ab/nsp68K8NaaGaaT2626AY.440.000158
ORF1ab/nsp68K8NaaGaaT2626B.10.000238
ORF1ab/nsp68K8NaaGaaT2525AY.10.009893
ORF1ab/nsp68K8NaaGaaT2121B.1.10.000381
ORF1ab/nsp68K8NaaGaaT1919AY.40.00003
ORF1ab/nsp68K8NaaGaaT1919B.1.1.2910.014105
ORF1ab/nsp68K8NaaGaaT1414AY.430.000062
ORF1ab/nsp68K8NaaGaaT1212AY.200.000466
ORF1ab/nsp68K8NaaGaaT1212R.10.00108
ORF1ab/nsp68K8NaaGaaT1111AY.120.10.003531
ORF1ab/nsp68K8NaaGaaT911D.20.000675
ORF1ab/nsp68K8NaaGaaC211D.20.00015
ORF1ab/nsp68K8NaaGaaT1010B.1.1.1530.010953
ORF1ab/nsp68K8NaaGaaC89B.1.5250.000905
ORF1ab/nsp68K8NaaGaaT19B.1.5250.000113
ORF1ab/nsp68K8NaaGaaT88AY.3.10.000682
ORF1ab/nsp68K8NaaGaaT77B.1.1600.000218
ORF1ab/nsp68K8NaaGaaC57B.1.466.20.001956
ORF1ab/nsp68K8NaaGaaT27B.1.466.20.000782
ORF1ab/nsp68K8NaaGaaT66AY.1090.004438
ORF1ab/nsp68K8NaaGaaT66B.1.1770.000079
ORF1ab/nsp68K8NaaGaaT66B.1.360.000875
ORF1ab/nsp68K8NaaGaaT55AY.1020.000133
ORF1ab/nsp68K8NaaGaaT55AY.1030.000031
ORF1ab/nsp68K8NaaGaaT55AY.1180.000313
ORF1ab/nsp68K8NaaGaaT55AY.450.000608
ORF1ab/nsp68K8NaaGaaT55P.20.000933
ORF1ab/nsp68K8NaaGaaT44AY.390.000099
ORF1ab/nsp68K8NaaGaaT44AY.420.000161
ORF1ab/nsp68K8NaaGaaT44B.1.1.250.002274
ORF1ab/nsp68K8NaaGaaT44B.1.1.5190.000159
ORF1ab/nsp68K8NaaGaaT44B.1.3960.002823
ORF1ab/nsp68K8NaaGaaT33AY.1000.000138
ORF1ab/nsp68K8NaaGaaT33AY.29.10.000662
ORF1ab/nsp68K8NaaGaaT33AY.980.000237
ORF1ab/nsp68K8NaaGaaT33B.1.4290.000071
ORF1ab/nsp68K8NaaGaaT22AY.30.00002
ORF1ab/nsp68K8NaaGaaT22AY.460.000208
ORF1ab/nsp68K8NaaGaaT22AY.540.000191
ORF1ab/nsp68K8NaaGaaT22AY.98.10.000097
ORF1ab/nsp68K8NaaGaaT22B.1.1.2160.001781
ORF1ab/nsp68K8NaaGaaT22B.1.1.330.000842
ORF1ab/nsp68K8NaaGaaT22B.1.1.3480.001592
ORF1ab/nsp68K8NaaGaaT22B.1.1.370.000386
ORF1ab/nsp68K8NaaGaaT22B.1.1.4020.022222
ORF1ab/nsp68K8NaaGaaT22B.1.1.4340.000697
ORF1ab/nsp68K8NaaGaaT22B.1.2060.001631
ORF1ab/nsp68K8NaaGaaT12B.1.2340.000132
ORF1ab/nsp68K8NaaGaaC12B.1.2340.000132
ORF1ab/nsp68K8NaaGaaT22B.1.3560.003454
ORF1ab/nsp68K8NaaGaaT22B.1.4270.000101
ORF1ab/nsp68K8NaaGaaT110.055556
ORF1ab/nsp68K8NaaGaaT11AY.1170.000085
ORF1ab/nsp68K8NaaGaaT11AY.1200.000037
ORF1ab/nsp68K8NaaGaaT11AY.230.00007
ORF1ab/nsp68K8NaaGaaT11AY.270.000065
ORF1ab/nsp68K8NaaGaaT11AY.370.000316
ORF1ab/nsp68K8NaaGaaC11AY.46.60.000072
ORF1ab/nsp68K8NaaGaaT11AY.50.000021
ORF1ab/nsp68K8NaaGaaT11AY.60.000041
ORF1ab/nsp68K8NaaGaaT11AY.660.00107
ORF1ab/nsp68K8NaaGaaT11AY.7.10.000113
ORF1ab/nsp68K8NaaGaaT11AY.840.000437
ORF1ab/nsp68K8NaaGaaT11AY.9.20.000037
ORF1ab/nsp68K8NaaGaaT11AY.910.00073
ORF1ab/nsp68K8NaaGaaT11AY.990.001049
ORF1ab/nsp68K8NaaGaaT11B0.000128
ORF1ab/nsp68K8NaaGaaT11B.1.1.1920.002309
ORF1ab/nsp68K8NaaGaaC11B.1.1.2800.003086
ORF1ab/nsp68K8NaaGaaT11B.1.1.2940.001266
ORF1ab/nsp68K8NaaGaaT11B.1.1.3090.005848
ORF1ab/nsp68K8NaaGaaT11B.1.1.3260.001761
ORF1ab/nsp68K8NaaGaaT11B.1.1.3880.045455
ORF1ab/nsp68K8NaaGaaT11B.1.1.450.014085
ORF1ab/nsp68K8NaaGaaT11B.1.1.4620.008621
ORF1ab/nsp68K8NaaGaaT11B.1.1040.00369
ORF1ab/nsp68K8NaaGaaT11B.1.177.200.001517
ORF1ab/nsp68K8NaaGaaT11B.1.177.330.001645
ORF1ab/nsp68K8NaaGaaT11B.1.2210.000071
ORF1ab/nsp68K8NaaGaaT11B.1.2400.000216
ORF1ab/nsp68K8NaaGaaT11B.1.258.170.000104
ORF1ab/nsp68K8NaaGaaT11B.1.3690.000285
ORF1ab/nsp68K8NaaGaaT11B.1.4700.001404
ORF1ab/nsp68K8NaaGaaT11B.1.5260.000024
ORF1ab/nsp68K8NaaGaaT11B.1.5750.000303
ORF1ab/nsp68K8NaaGaaT11B.1.5960.000087
ORF1ab/nsp68K8NaaGaaC11B.1.6360.006711
ORF1ab/nsp68K8NaaGaaT11B.1.760.011364
ORF1ab/nsp68K8NaaGaaT11B.1.910.002075
ORF1ab/nsp68K8NaaGaaT11P.10.000016
ORF1ab/nsp68K8NaaGaaT11P.1.140.000048
ORF1ab/nsp68K8NaaGaaT11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.