CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp6 : Mut = K263N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp6263K263NK3832NnonsynaaGaaT200820040.99800811759-11761
ORF1ab/nsp6263K263NK3832NnonsynaaGaaC200840.0019920311759-11761

Details of the mutation K263N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp6263K263NaaGaaT20042008All0.000383
ORF1ab/nsp6263K263NaaGaaC42008All0.000001
ORF1ab/nsp6263K263NaaGaaT528528AY.40.000822
ORF1ab/nsp6263K263NaaGaaT243243B.1.221.20.975904
ORF1ab/nsp6263K263NaaGaaT150150AY.34.10.076492
ORF1ab/nsp6263K263NaaGaaT9898B.1.177.810.018554
ORF1ab/nsp6263K263NaaGaaT9191B.1.617.20.000343
ORF1ab/nsp6263K263NaaGaaT8787B.1.2210.00618
ORF1ab/nsp6263K263NaaGaaT7676B.10.000696
ORF1ab/nsp6263K263NaaGaaT6363B.1.1.70.000056
ORF1ab/nsp6263K263NaaGaaT6262AY.440.000377
ORF1ab/nsp6263K263NaaGaaT5454AY.430.000239
ORF1ab/nsp6263K263NaaGaaT3030AY.250.00018
ORF1ab/nsp6263K263NaaGaaT2424AY.1030.000149
ORF1ab/nsp6263K263NaaGaaT2323B.1.221.10.06686
ORF1ab/nsp6263K263NaaGaaT2222AY.1020.000583
ORF1ab/nsp6263K263NaaGaaT2020B.1.2430.001392
ORF1ab/nsp6263K263NaaGaaT1616AY.1000.000736
ORF1ab/nsp6263K263NaaGaaT1516B.1.1770.000198
ORF1ab/nsp6263K263NaaGaaC116B.1.1770.000013
ORF1ab/nsp6263K263NaaGaaT1515B.1.10.000272
ORF1ab/nsp6263K263NaaGaaT1515B.1.1600.000468
ORF1ab/nsp6263K263NaaGaaT1414B.1.1.4640.020619
ORF1ab/nsp6263K263NaaGaaT1313AY.30.000129
ORF1ab/nsp6263K263NaaGaaT1111AY.390.000272
ORF1ab/nsp6263K263NaaGaaT1111B.1.177.860.002018
ORF1ab/nsp6263K263NaaGaaT1010AY.330.000668
ORF1ab/nsp6263K263NaaGaaT1010B.1.20.000088
ORF1ab/nsp6263K263NaaGaaT1010B.1.360.001459
ORF1ab/nsp6263K263NaaGaaT99B.1.4290.000212
ORF1ab/nsp6263K263NaaGaaT99C.160.009544
ORF1ab/nsp6263K263NaaGaaT88B.1.1660.067797
ORF1ab/nsp6263K263NaaGaaT77AY.680.001916
ORF1ab/nsp6263K263NaaGaaT77B.1.1.4320.008861
ORF1ab/nsp6263K263NaaGaaT66AY.3.10.000512
ORF1ab/nsp6263K263NaaGaaT66AY.50.000124
ORF1ab/nsp6263K263NaaGaaT66B.1.5300.042857
ORF1ab/nsp6263K263NaaGaaT55AY.1190.000177
ORF1ab/nsp6263K263NaaGaaT55AY.260.000142
ORF1ab/nsp6263K263NaaGaaT55AY.5.40.001384
ORF1ab/nsp6263K263NaaGaaT55B.1.1.3060.002192
ORF1ab/nsp6263K263NaaGaaT55B.1.1.3170.002058
ORF1ab/nsp6263K263NaaGaaT55B.1.1.5190.000199
ORF1ab/nsp6263K263NaaGaaT55B.1.2400.001078
ORF1ab/nsp6263K263NaaGaaT55B.1.5170.002135
ORF1ab/nsp6263K263NaaGaaT44AY.1170.000338
ORF1ab/nsp6263K263NaaGaaT44AY.290.000063
ORF1ab/nsp6263K263NaaGaaT44AY.470.000124
ORF1ab/nsp6263K263NaaGaaT44AY.60.000165
ORF1ab/nsp6263K263NaaGaaT44AY.7.20.002237
ORF1ab/nsp6263K263NaaGaaT44AY.910.002922
ORF1ab/nsp6263K263NaaGaaT44B.1.4560.013072
ORF1ab/nsp6263K263NaaGaaT44B.1.6210.000354
ORF1ab/nsp6263K263NaaGaaT44P.20.000747
ORF1ab/nsp6263K263NaaGaaT33AY.1180.000188
ORF1ab/nsp6263K263NaaGaaT33AY.46.40.000494
ORF1ab/nsp6263K263NaaGaaT33B0.000383
ORF1ab/nsp6263K263NaaGaaT33B.1.1.2070.003546
ORF1ab/nsp6263K263NaaGaaT33B.1.1.3980.009677
ORF1ab/nsp6263K263NaaGaaT33B.1.1.4200.003018
ORF1ab/nsp6263K263NaaGaaT33B.1.177.440.001557
ORF1ab/nsp6263K263NaaGaaT33B.1.177.60.00293
ORF1ab/nsp6263K263NaaGaaT33B.1.2580.0002
ORF1ab/nsp6263K263NaaGaaT33B.1.36.290.001552
ORF1ab/nsp6263K263NaaGaaT33B.1.438.10.000322
ORF1ab/nsp6263K263NaaGaaT33B.1.5240.004219
ORF1ab/nsp6263K263NaaGaaT33B.1.5580.013699
ORF1ab/nsp6263K263NaaGaaT22AY.120.2.10.000997
ORF1ab/nsp6263K263NaaGaaT22AY.200.000078
ORF1ab/nsp6263K263NaaGaaT22AY.350.000466
ORF1ab/nsp6263K263NaaGaaT22AY.360.000296
ORF1ab/nsp6263K263NaaGaaT22AY.39.10.000079
ORF1ab/nsp6263K263NaaGaaT22AY.4.20.000043
ORF1ab/nsp6263K263NaaGaaT22AY.420.00008
ORF1ab/nsp6263K263NaaGaaT22AY.460.000208
ORF1ab/nsp6263K263NaaGaaT22AY.9.10.000167
ORF1ab/nsp6263K263NaaGaaT22B.1.1.280.000622
ORF1ab/nsp6263K263NaaGaaT22B.1.1.2800.006173
ORF1ab/nsp6263K263NaaGaaT22B.1.1.2840.000215
ORF1ab/nsp6263K263NaaGaaT22B.1.1.2940.002532
ORF1ab/nsp6263K263NaaGaaT22B.1.1.3690.000892
ORF1ab/nsp6263K263NaaGaaT22B.1.1.4620.017241
ORF1ab/nsp6263K263NaaGaaT22B.1.1.630.000772
ORF1ab/nsp6263K263NaaGaaT22B.1.1.670.009132
ORF1ab/nsp6263K263NaaGaaT22B.1.177.110.003396
ORF1ab/nsp6263K263NaaGaaT22B.1.177.210.000153
ORF1ab/nsp6263K263NaaGaaT22B.1.177.560.001335
ORF1ab/nsp6263K263NaaGaaT22B.1.177.830.002963
ORF1ab/nsp6263K263NaaGaaT22B.1.2340.000264
ORF1ab/nsp6263K263NaaGaaT22B.1.4280.002041
ORF1ab/nsp6263K263NaaGaaT22B.1.5260.000047
ORF1ab/nsp6263K263NaaGaaT22B.1.617.10.000258
ORF1ab/nsp6263K263NaaGaaT22C.350.001548
ORF1ab/nsp6263K263NaaGaaT22C.370.000232
ORF1ab/nsp6263K263NaaGaaT22P.1.150.000465
ORF1ab/nsp6263K263NaaGaaT22Q.30.00029
ORF1ab/nsp6263K263NaaGaaT11A0.000387
ORF1ab/nsp6263K263NaaGaaT11A.20.000662
ORF1ab/nsp6263K263NaaGaaT11AD.20.000219
ORF1ab/nsp6263K263NaaGaaT11AH.20.012048
ORF1ab/nsp6263K263NaaGaaT11AY.1060.000335
ORF1ab/nsp6263K263NaaGaaT11AY.110.001339
ORF1ab/nsp6263K263NaaGaaT11AY.1110.000183
ORF1ab/nsp6263K263NaaGaaT11AY.1200.000037
ORF1ab/nsp6263K263NaaGaaT11AY.340.000097
ORF1ab/nsp6263K263NaaGaaT11AY.4.50.000107
ORF1ab/nsp6263K263NaaGaaT11AY.450.000122
ORF1ab/nsp6263K263NaaGaaT11AY.46.60.000072
ORF1ab/nsp6263K263NaaGaaT11AY.520.000814
ORF1ab/nsp6263K263NaaGaaT11AY.550.000917
ORF1ab/nsp6263K263NaaGaaT11AY.580.000907
ORF1ab/nsp6263K263NaaGaaT11AY.650.000533
ORF1ab/nsp6263K263NaaGaaT11AY.750.000056
ORF1ab/nsp6263K263NaaGaaT11AY.75.10.00018
ORF1ab/nsp6263K263NaaGaaT11AY.780.001541
ORF1ab/nsp6263K263NaaGaaT11AY.840.000437
ORF1ab/nsp6263K263NaaGaaT11AY.920.000287
ORF1ab/nsp6263K263NaaGaaT11AY.980.000079
ORF1ab/nsp6263K263NaaGaaT11AY.98.10.000048
ORF1ab/nsp6263K263NaaGaaT11B.1.1.10.000327
ORF1ab/nsp6263K263NaaGaaT11B.1.1.1410.002012
ORF1ab/nsp6263K263NaaGaaT11B.1.1.1700.001247
ORF1ab/nsp6263K263NaaGaaT11B.1.1.1940.00495
ORF1ab/nsp6263K263NaaGaaT11B.1.1.2040.00304
ORF1ab/nsp6263K263NaaGaaT11B.1.1.2140.000055
ORF1ab/nsp6263K263NaaGaaT11B.1.1.2220.000204
ORF1ab/nsp6263K263NaaGaaT11B.1.1.250.000569
ORF1ab/nsp6263K263NaaGaaT11B.1.1.3010.001179
ORF1ab/nsp6263K263NaaGaaT11B.1.1.3180.000302
ORF1ab/nsp6263K263NaaGaaT11B.1.1.3260.001761
ORF1ab/nsp6263K263NaaGaaT11B.1.1.330.000421
ORF1ab/nsp6263K263NaaGaaT11B.1.1.3680.003086
ORF1ab/nsp6263K263NaaGaaC11B.1.1.390.00051
ORF1ab/nsp6263K263NaaGaaT11B.1.1.3910.008547
ORF1ab/nsp6263K263NaaGaaT11B.1.1.4120.007634
ORF1ab/nsp6263K263NaaGaaT11B.1.1.4340.000349
ORF1ab/nsp6263K263NaaGaaT11B.1.1.500.000679
ORF1ab/nsp6263K263NaaGaaT11B.1.1570.002985
ORF1ab/nsp6263K263NaaGaaT11B.1.160.160.000929
ORF1ab/nsp6263K263NaaGaaT11B.1.160.80.001289
ORF1ab/nsp6263K263NaaGaaT11B.1.177.200.001517
ORF1ab/nsp6263K263NaaGaaT11B.1.177.50.001242
ORF1ab/nsp6263K263NaaGaaT11B.1.177.720.00339
ORF1ab/nsp6263K263NaaGaaT11B.1.3010.005917
ORF1ab/nsp6263K263NaaGaaT11B.1.36.10.00114
ORF1ab/nsp6263K263NaaGaaT11B.1.36.180.00042
ORF1ab/nsp6263K263NaaGaaT11B.1.3690.000285
ORF1ab/nsp6263K263NaaGaaT11B.1.4000.000429
ORF1ab/nsp6263K263NaaGaaT11B.1.4080.00369
ORF1ab/nsp6263K263NaaGaaC11B.1.4160.001269
ORF1ab/nsp6263K263NaaGaaT11B.1.4250.002994
ORF1ab/nsp6263K263NaaGaaT11B.1.4430.004673
ORF1ab/nsp6263K263NaaGaaT11B.1.5400.009709
ORF1ab/nsp6263K263NaaGaaT11B.1.5640.000426
ORF1ab/nsp6263K263NaaGaaT11B.1.5760.000907
ORF1ab/nsp6263K263NaaGaaT11B.1.5960.000087
ORF1ab/nsp6263K263NaaGaaT11B.1.6090.000479
ORF1ab/nsp6263K263NaaGaaT11B.1.6230.000536
ORF1ab/nsp6263K263NaaGaaT11B.60.00091
ORF1ab/nsp6263K263NaaGaaC11D.20.000075
ORF1ab/nsp6263K263NaaGaaT11P.1.140.000048

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.