CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp6 : Mut = H11Q

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp611H11QH3580QnonsyncaCcaA20760207480.99942211003-11005
ORF1ab/nsp611H11QH3580QnonsyncaCcaG20760120.00057803511003-11005

Details of the mutation H11Q within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp611H11QcaCcaA2074820760All0.003968
ORF1ab/nsp611H11QcaCcaG1220760All0.000002
ORF1ab/nsp611H11QcaCcaA85878588B.1.617.20.032334
ORF1ab/nsp611H11QcaCcaG18588B.1.617.20.000004
ORF1ab/nsp611H11QcaCcaA37933793AY.350.883943
ORF1ab/nsp611H11QcaCcaA19201920A.2.50.958084
ORF1ab/nsp611H11QcaCcaA17051705AY.480.793023
ORF1ab/nsp611H11QcaCcaA16661666B.1.6230.893777
ORF1ab/nsp611H11QcaCcaA610610A.2.5.20.959119
ORF1ab/nsp611H11QcaCcaA570570AY.16.10.267857
ORF1ab/nsp611H11QcaCcaA315315B.1.1.2650.993691
ORF1ab/nsp611H11QcaCcaA202202A.2.5.10.971154
ORF1ab/nsp611H11QcaCcaA159159AY.130.025596
ORF1ab/nsp611H11QcaCcaA142142AY.440.000864
ORF1ab/nsp611H11QcaCcaA124124AY.1080.136714
ORF1ab/nsp611H11QcaCcaA104104AY.230.007254
ORF1ab/nsp611H11QcaCcaA8282A.2.5.30.845361
ORF1ab/nsp611H11QcaCcaA6767B.10.000614
ORF1ab/nsp611H11QcaCcaA5858AY.920.016662
ORF1ab/nsp611H11QcaCcaA5252AY.590.027542
ORF1ab/nsp611H11QcaCcaA4747AY.680.012866
ORF1ab/nsp611H11QcaCcaA3940AY.430.000173
ORF1ab/nsp611H11QcaCcaG140AY.430.000004
ORF1ab/nsp611H11QcaCcaA3636AY.660.038503
ORF1ab/nsp611H11QcaCcaA3636AY.980.002844
ORF1ab/nsp611H11QcaCcaA3535AY.190.039909
ORF1ab/nsp611H11QcaCcaA3333AY.520.026873
ORF1ab/nsp611H11QcaCcaA2727B.1.3240.043339
ORF1ab/nsp611H11QcaCcaA2626AY.370.008217
ORF1ab/nsp611H11QcaCcaA2020AY.5.40.005534
ORF1ab/nsp611H11QcaCcaA1818AY.1160.005162
ORF1ab/nsp611H11QcaCcaA1717AY.540.001621
ORF1ab/nsp611H11QcaCcaA1111B.1.5740.023656
ORF1ab/nsp611H11QcaCcaA1010AY.470.000311
ORF1ab/nsp611H11QcaCcaA99AY.1210.001218
ORF1ab/nsp611H11QcaCcaA99AY.240.003879
ORF1ab/nsp611H11QcaCcaA99AY.780.013867
ORF1ab/nsp611H11QcaCcaA88AY.1030.00005
ORF1ab/nsp611H11QcaCcaA88AY.770.009019
ORF1ab/nsp611H11QcaCcaA77AY.98.10.000339
ORF1ab/nsp611H11QcaCcaA66AY.1180.000376
ORF1ab/nsp611H11QcaCcaA66AY.250.000036
ORF1ab/nsp611H11QcaCcaA66AY.550.005505
ORF1ab/nsp611H11QcaCcaA66AY.640.003571
ORF1ab/nsp611H11QcaCcaA66AY.870.004996
ORF1ab/nsp611H11QcaCcaA66B.1.1600.000187
ORF1ab/nsp611H11QcaCcaA66B.1.617.10.000774
ORF1ab/nsp611H11QcaCcaA55AY.450.000608
ORF1ab/nsp611H11QcaCcaA55AY.610.000524
ORF1ab/nsp611H11QcaCcaA55AY.620.002179
ORF1ab/nsp611H11QcaCcaA55B0.000639
ORF1ab/nsp611H11QcaCcaA45B.1.1.70.000004
ORF1ab/nsp611H11QcaCcaG15B.1.1.70.000001
ORF1ab/nsp611H11QcaCcaA55B.1.3670.003962
ORF1ab/nsp611H11QcaCcaA44AY.1000.000184
ORF1ab/nsp611H11QcaCcaA44AY.40.000006
ORF1ab/nsp611H11QcaCcaA44AY.9.20.000147
ORF1ab/nsp611H11QcaCcaA34B.1.4290.000071
ORF1ab/nsp611H11QcaCcaG14B.1.4290.000024
ORF1ab/nsp611H11QcaCcaA230.111111
ORF1ab/nsp611H11QcaCcaG130.055556
ORF1ab/nsp611H11QcaCcaA33AY.1170.000254
ORF1ab/nsp611H11QcaCcaA33AY.200.000117
ORF1ab/nsp611H11QcaCcaA33AY.220.006276
ORF1ab/nsp611H11QcaCcaA33AY.530.000863
ORF1ab/nsp611H11QcaCcaA33AY.560.004815
ORF1ab/nsp611H11QcaCcaA33AY.750.000168
ORF1ab/nsp611H11QcaCcaA33AY.880.002653
ORF1ab/nsp611H11QcaCcaA33B.1.10.000054
ORF1ab/nsp611H11QcaCcaG33C.350.002322
ORF1ab/nsp611H11QcaCcaA22AY.1010.000981
ORF1ab/nsp611H11QcaCcaA22AY.1060.00067
ORF1ab/nsp611H11QcaCcaA22AY.110.002677
ORF1ab/nsp611H11QcaCcaA22AY.120.000632
ORF1ab/nsp611H11QcaCcaA22AY.420.00008
ORF1ab/nsp611H11QcaCcaA22AY.700.000417
ORF1ab/nsp611H11QcaCcaA22AY.710.00095
ORF1ab/nsp611H11QcaCcaA22AY.820.002714
ORF1ab/nsp611H11QcaCcaA22AY.930.000546
ORF1ab/nsp611H11QcaCcaA22B.1.1570.00597
ORF1ab/nsp611H11QcaCcaA22B.1.20.000018
ORF1ab/nsp611H11QcaCcaG22B.1.2100.004264
ORF1ab/nsp611H11QcaCcaA22B.1.2140.007326
ORF1ab/nsp611H11QcaCcaA22B.1.2340.000264
ORF1ab/nsp611H11QcaCcaA22B.1.2390.002442
ORF1ab/nsp611H11QcaCcaA22B.1.36.170.000988
ORF1ab/nsp611H11QcaCcaG12B.1.4270.00005
ORF1ab/nsp611H11QcaCcaA12B.1.4270.00005
ORF1ab/nsp611H11QcaCcaA22B.1.5260.000047
ORF1ab/nsp611H11QcaCcaA11A0.000387
ORF1ab/nsp611H11QcaCcaA11A.2.40.003367
ORF1ab/nsp611H11QcaCcaA11AU.20.002421
ORF1ab/nsp611H11QcaCcaA11AY.100.00053
ORF1ab/nsp611H11QcaCcaA11AY.1100.000113
ORF1ab/nsp611H11QcaCcaA11AY.270.000065
ORF1ab/nsp611H11QcaCcaA11AY.280.00189
ORF1ab/nsp611H11QcaCcaA11AY.30.00001
ORF1ab/nsp611H11QcaCcaA11AY.320.000532
ORF1ab/nsp611H11QcaCcaA11AY.330.000067
ORF1ab/nsp611H11QcaCcaA11AY.380.000499
ORF1ab/nsp611H11QcaCcaA11AY.410.000294
ORF1ab/nsp611H11QcaCcaA11AY.460.000104
ORF1ab/nsp611H11QcaCcaA11AY.5.30.000337
ORF1ab/nsp611H11QcaCcaA11AY.510.000909
ORF1ab/nsp611H11QcaCcaA11AY.580.000907
ORF1ab/nsp611H11QcaCcaA11AY.670.000464
ORF1ab/nsp611H11QcaCcaA11AY.740.000116
ORF1ab/nsp611H11QcaCcaA11AY.850.000427
ORF1ab/nsp611H11QcaCcaA11AY.950.000761
ORF1ab/nsp611H11QcaCcaA11AY.960.002075
ORF1ab/nsp611H11QcaCcaA11AY.99.20.000092
ORF1ab/nsp611H11QcaCcaA11B.1.1.1760.000439
ORF1ab/nsp611H11QcaCcaA11B.1.1.2200.001859
ORF1ab/nsp611H11QcaCcaA11B.1.1.2240.014286
ORF1ab/nsp611H11QcaCcaA11B.1.1.2940.001266
ORF1ab/nsp611H11QcaCcaA11B.1.1.3180.000302
ORF1ab/nsp611H11QcaCcaA11B.1.1.3510.002793
ORF1ab/nsp611H11QcaCcaA11B.1.177.730.000566
ORF1ab/nsp611H11QcaCcaA11B.1.2210.000071
ORF1ab/nsp611H11QcaCcaA11B.1.5060.02381
ORF1ab/nsp611H11QcaCcaA11B.1.5540.004405
ORF1ab/nsp611H11QcaCcaA11B.1.5610.000397
ORF1ab/nsp611H11QcaCcaA11B.1.5950.000261
ORF1ab/nsp611H11QcaCcaA11B.1.5960.000087
ORF1ab/nsp611H11QcaCcaA11B.1.6090.000479
ORF1ab/nsp611H11QcaCcaA11B.1.6280.000352
ORF1ab/nsp611H11QcaCcaA11B.520.010101
ORF1ab/nsp611H11QcaCcaA11B.610.005747
ORF1ab/nsp611H11QcaCcaA11C.370.000116
ORF1ab/nsp611H11QcaCcaA11C.60.037037
ORF1ab/nsp611H11QcaCcaG11D.20.000075
ORF1ab/nsp611H11QcaCcaA11P.10.000016

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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