CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp6 : Mut = G107S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp6107G107SG3676SnonsynGgtAgt19753197510.99989911291-11293
ORF1ab/nsp6107G107SG3676SnonsynGGTTCA1975310.000050625211291-11293
ORF1ab/nsp6107G107SG3676SnonsynGgTAgC1975310.000050625211291-11293

Details of the mutation G107S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp6107G107SGgtAgt1975119753All0.003778
ORF1ab/nsp6107G107SGGTTCA119753All0
ORF1ab/nsp6107G107SGgTAgC119753All0
ORF1ab/nsp6107G107SGgtAgt1553715538B.1.1.70.013909
ORF1ab/nsp6107G107SGGTTCA115538B.1.1.70.000001
ORF1ab/nsp6107G107SGgtAgt983983Q.20.603067
ORF1ab/nsp6107G107SGgtAgt567567P.1.10.180114
ORF1ab/nsp6107G107SGgtAgt455456P.10.007168
ORF1ab/nsp6107G107SGgTAgC1456P.10.000016
ORF1ab/nsp6107G107SGgtAgt236236B.1.6370.017245
ORF1ab/nsp6107G107SGgtAgt220220B.1.3510.00654
ORF1ab/nsp6107G107SGgtAgt195195AY.40.000304
ORF1ab/nsp6107G107SGgtAgt136136B.1.5250.01539
ORF1ab/nsp6107G107SGgtAgt136136P.1.150.031599
ORF1ab/nsp6107G107SGgtAgt126126B.1.5260.002962
ORF1ab/nsp6107G107SGgtAgt123123Q.30.017839
ORF1ab/nsp6107G107SGgtAgt9898C.370.011374
ORF1ab/nsp6107G107SGgtAgt9595B.10.00087
ORF1ab/nsp6107G107SGgtAgt7979Q.10.00998
ORF1ab/nsp6107G107SGgtAgt6565AY.1190.002295
ORF1ab/nsp6107G107SGgtAgt5555AY.440.000335
ORF1ab/nsp6107G107SGgtAgt4242B.1.10.000762
ORF1ab/nsp6107G107SGgtAgt4242P.1.170.006794
ORF1ab/nsp6107G107SGgtAgt4242Q.40.0191
ORF1ab/nsp6107G107SGgtAgt3535B.1.617.20.000132
ORF1ab/nsp6107G107SGgtAgt2929B.1.6010.878788
ORF1ab/nsp6107G107SGgtAgt2828P.1.70.00894
ORF1ab/nsp6107G107SGgtAgt2727B.1.351.50.016187
ORF1ab/nsp6107G107SGgtAgt2323B.1.1.3180.00694
ORF1ab/nsp6107G107SGgtAgt2121B.1.351.20.006354
ORF1ab/nsp6107G107SGgtAgt2020P.1.120.009681
ORF1ab/nsp6107G107SGgtAgt1818AY.1030.000112
ORF1ab/nsp6107G107SGgtAgt1818P.1.140.00086
ORF1ab/nsp6107G107SGgtAgt1717B.1.4700.023876
ORF1ab/nsp6107G107SGgtAgt1717P.1.100.004581
ORF1ab/nsp6107G107SGgtAgt1515B.1.2410.012175
ORF1ab/nsp6107G107SGgtAgt1414B.1.6280.004933
ORF1ab/nsp6107G107SGgtAgt1313AZ.30.019757
ORF1ab/nsp6107G107SGgtAgt1212B.1.1.2220.002448
ORF1ab/nsp6107G107SGgtAgt1212B.1.1.5190.000477
ORF1ab/nsp6107G107SGgtAgt1111AY.1100.00124
ORF1ab/nsp6107G107SGgtAgt1010B.1.760.113636
ORF1ab/nsp6107G107SGgtAgt1010B.6.60.008889
ORF1ab/nsp6107G107SGgtAgt99AY.210.017078
ORF1ab/nsp6107G107SGgtAgt99B.1.5240.012658
ORF1ab/nsp6107G107SGgtAgt77B.1.214.20.004197
ORF1ab/nsp6107G107SGgtAgt77C.37.10.018325
ORF1ab/nsp6107G107SGgtAgt77P.1.40.006836
ORF1ab/nsp6107G107SGgtAgt66AY.390.000148
ORF1ab/nsp6107G107SGgtAgt66B.1.351.30.005259
ORF1ab/nsp6107G107SGgtAgt55AY.1000.00023
ORF1ab/nsp6107G107SGgtAgt55AZ.20.004105
ORF1ab/nsp6107G107SGgtAgt55B.1.619.10.003207
ORF1ab/nsp6107G107SGgtAgt55B.1.6360.033557
ORF1ab/nsp6107G107SGgtAgt44AY.46.20.002541
ORF1ab/nsp6107G107SGgtAgt44B.1.1.280.001245
ORF1ab/nsp6107G107SGgtAgt44B.1.1770.000053
ORF1ab/nsp6107G107SGgtAgt44B.1.20.000035
ORF1ab/nsp6107G107SGgtAgt44B.1.6190.003484
ORF1ab/nsp6107G107SGgtAgt44P.1.20.004624
ORF1ab/nsp6107G107SGgtAgt44Q.80.00066
ORF1ab/nsp6107G107SGgtAgt33AY.50.000062
ORF1ab/nsp6107G107SGgtAgt33AY.530.000863
ORF1ab/nsp6107G107SGgtAgt33B.1.1.3720.002066
ORF1ab/nsp6107G107SGgtAgt33B.1.1.4480.006098
ORF1ab/nsp6107G107SGgtAgt33B.1.2400.000647
ORF1ab/nsp6107G107SGgtAgt33B.1.6250.007059
ORF1ab/nsp6107G107SGgtAgt22AY.200.000078
ORF1ab/nsp6107G107SGgtAgt22AY.250.000012
ORF1ab/nsp6107G107SGgtAgt22AY.290.000032
ORF1ab/nsp6107G107SGgtAgt22AY.30.00002
ORF1ab/nsp6107G107SGgtAgt22AY.330.000134
ORF1ab/nsp6107G107SGgtAgt22AY.430.000009
ORF1ab/nsp6107G107SGgtAgt22B0.000256
ORF1ab/nsp6107G107SGgtAgt22B.1.177.730.001133
ORF1ab/nsp6107G107SGgtAgt22B.1.36.70.008
ORF1ab/nsp6107G107SGgtAgt11AV.10.005051
ORF1ab/nsp6107G107SGgtAgt11AY.1020.000027
ORF1ab/nsp6107G107SGgtAgt11AY.1170.000085
ORF1ab/nsp6107G107SGgtAgt11AY.16.10.00047
ORF1ab/nsp6107G107SGgtAgt11AY.230.00007
ORF1ab/nsp6107G107SGgtAgt11AY.300.000396
ORF1ab/nsp6107G107SGgtAgt11AY.4.20.000022
ORF1ab/nsp6107G107SGgtAgt11AY.610.000105
ORF1ab/nsp6107G107SGgtAgt11AY.75.10.00018
ORF1ab/nsp6107G107SGgtAgt11AY.9.10.000084
ORF1ab/nsp6107G107SGgtAgt11AY.9.20.000037
ORF1ab/nsp6107G107SGgtAgt11AZ.40.003356
ORF1ab/nsp6107G107SGgtAgt11B.1.1.1440.028571
ORF1ab/nsp6107G107SGgtAgt11B.1.1.3170.000412
ORF1ab/nsp6107G107SGgtAgt11B.1.1.330.000421
ORF1ab/nsp6107G107SGgtAgt11B.1.1.4090.002833
ORF1ab/nsp6107G107SGgtAgt11B.1.1.5240.020833
ORF1ab/nsp6107G107SGgtAgt11B.1.1.700.000341
ORF1ab/nsp6107G107SGgtAgt11B.1.1600.000031
ORF1ab/nsp6107G107SGgtAgt11B.1.177.170.000821
ORF1ab/nsp6107G107SGgtAgt11B.1.177.440.000519
ORF1ab/nsp6107G107SGgtAgt11B.1.214.30.007143
ORF1ab/nsp6107G107SGgtAgt11B.1.2210.000071
ORF1ab/nsp6107G107SGgtAgt11B.1.2370.004975
ORF1ab/nsp6107G107SGgtAgt11B.1.258.140.00098
ORF1ab/nsp6107G107SGgtAgt11B.1.258.170.000104
ORF1ab/nsp6107G107SGgtAgt11B.1.4290.000024
ORF1ab/nsp6107G107SGgtAgt11B.1.5950.000261
ORF1ab/nsp6107G107SGgtAgt11C.390.018868
ORF1ab/nsp6107G107SGgtAgt11N.90.005952
ORF1ab/nsp6107G107SGgtAgt11P.1.130.000898
ORF1ab/nsp6107G107SGgtAgt11P.1.160.000374
ORF1ab/nsp6107G107SGgtAgt11P.1.17.10.000875
ORF1ab/nsp6107G107SGgtAgt11Q.60.006623

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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