CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp6 : Mut = F108L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp6108F108LF3677LnonsynttTttG23897235760.98656711294-11296
ORF1ab/nsp6108F108LF3677LnonsynttTttA238971660.0069464811294-11296
ORF1ab/nsp6108F108LF3677LnonsynTttCtt238971510.0063187811294-11296
ORF1ab/nsp6108F108LF3677LnonsynTtTCtG2389740.00016738511294-11296

Details of the mutation F108L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp6108F108LttTttG2357623897All0.004509
ORF1ab/nsp6108F108LttTttA16623897All0.000032
ORF1ab/nsp6108F108LTttCtt15123897All0.000029
ORF1ab/nsp6108F108LTtTCtG423897All0.000001
ORF1ab/nsp6108F108LttTttG1911319151B.1.1.70.01711
ORF1ab/nsp6108F108LttTttA3419151B.1.1.70.00003
ORF1ab/nsp6108F108LTtTCtG419151B.1.1.70.000004
ORF1ab/nsp6108F108LttTttG983983Q.20.603067
ORF1ab/nsp6108F108LttTttG647738P.10.010193
ORF1ab/nsp6108F108LttTttA91738P.10.001434
ORF1ab/nsp6108F108LttTttG580580P.1.10.184244
ORF1ab/nsp6108F108LttTttG335336B.1.3510.009958
ORF1ab/nsp6108F108LttTttA1336B.1.3510.00003
ORF1ab/nsp6108F108LttTttG274274B.1.6370.020022
ORF1ab/nsp6108F108LttTttG201205B.1.5250.022745
ORF1ab/nsp6108F108LttTttA4205B.1.5250.000453
ORF1ab/nsp6108F108LttTttG202204P.1.150.046933
ORF1ab/nsp6108F108LttTttA2204P.1.150.000465
ORF1ab/nsp6108F108LttTttG165166B.1.5260.003878
ORF1ab/nsp6108F108LttTttA1166B.1.5260.000024
ORF1ab/nsp6108F108LttTttG126138C.370.014624
ORF1ab/nsp6108F108LttTttA12138C.370.001393
ORF1ab/nsp6108F108LttTttG133133Q.30.019289
ORF1ab/nsp6108F108LTttCtt114114B.1.466.20.044601
ORF1ab/nsp6108F108LttTttG99100Q.10.012506
ORF1ab/nsp6108F108LttTttA1100Q.10.000126
ORF1ab/nsp6108F108LttTttG8488B.1.10.001524
ORF1ab/nsp6108F108LTttCtt388B.1.10.000054
ORF1ab/nsp6108F108LttTttA188B.1.10.000018
ORF1ab/nsp6108F108LttTttG5959P.1.170.009544
ORF1ab/nsp6108F108LttTttG5358B.10.000485
ORF1ab/nsp6108F108LTttCtt458B.10.000037
ORF1ab/nsp6108F108LttTttA158B.10.000009
ORF1ab/nsp6108F108LttTttG5555Q.40.025011
ORF1ab/nsp6108F108LttTttG4849P.1.140.002294
ORF1ab/nsp6108F108LttTttA149P.1.140.000048
ORF1ab/nsp6108F108LttTttG4747P.1.70.015006
ORF1ab/nsp6108F108LttTttG3838B.1.351.50.022782
ORF1ab/nsp6108F108LttTttG3536P.1.120.016941
ORF1ab/nsp6108F108LttTttA136P.1.120.000484
ORF1ab/nsp6108F108LttTttG3535B.1.1.3180.010561
ORF1ab/nsp6108F108LttTttG3030B.1.6280.010571
ORF1ab/nsp6108F108LttTttG2424B.1.351.20.007262
ORF1ab/nsp6108F108LttTttG1920P.1.100.00512
ORF1ab/nsp6108F108LttTttA120P.1.100.000269
ORF1ab/nsp6108F108LttTttG1919B.1.4700.026685
ORF1ab/nsp6108F108LttTttG1818B.1.619.10.011546
ORF1ab/nsp6108F108LttTttG1717B.1.2410.013799
ORF1ab/nsp6108F108LttTttG1616AZ.30.024316
ORF1ab/nsp6108F108LttTttG814P.1.40.007812
ORF1ab/nsp6108F108LttTttA614P.1.40.005859
ORF1ab/nsp6108F108LttTttG1013P.1.20.011561
ORF1ab/nsp6108F108LttTttA313P.1.20.003468
ORF1ab/nsp6108F108LttTttG1010B.1.214.20.005995
ORF1ab/nsp6108F108LttTttG1010C.37.10.026178
ORF1ab/nsp6108F108LttTttG88B.1.351.30.007011
ORF1ab/nsp6108F108LTttCtt77AY.950.005327
ORF1ab/nsp6108F108LttTttG77AZ.40.02349
ORF1ab/nsp6108F108LttTttG66AZ.20.004926
ORF1ab/nsp6108F108LTttCtt66B.1.1.5190.000238
ORF1ab/nsp6108F108LttTttG66B.1.6190.005226
ORF1ab/nsp6108F108LttTttG46B.1.6250.009412
ORF1ab/nsp6108F108LttTttA26B.1.6250.004706
ORF1ab/nsp6108F108LttTttG55B.1.6360.033557
ORF1ab/nsp6108F108LttTttG44B.1.1.280.001245
ORF1ab/nsp6108F108LttTttG44B.1.177.730.002265
ORF1ab/nsp6108F108LTttCtt34B.1.5950.000783
ORF1ab/nsp6108F108LttTttG14B.1.5950.000261
ORF1ab/nsp6108F108LttTttG44Q.80.00066
ORF1ab/nsp6108F108LttTttA33AY.390.000074
ORF1ab/nsp6108F108LttTttG33B.1.1.3720.002066
ORF1ab/nsp6108F108LTttCtt23B.1.20.000018
ORF1ab/nsp6108F108LttTttG13B.1.20.000009
ORF1ab/nsp6108F108LttTttG33P.1.80.014354
ORF1ab/nsp6108F108LTttCtt22AY.40.000003
ORF1ab/nsp6108F108LTttCtt12AY.9.20.000037
ORF1ab/nsp6108F108LttTttG12AY.9.20.000037
ORF1ab/nsp6108F108LttTttG22B0.000256
ORF1ab/nsp6108F108LttTttG12B.1.1600.000031
ORF1ab/nsp6108F108LTttCtt12B.1.1600.000031
ORF1ab/nsp6108F108LttTttG12B.1.1770.000013
ORF1ab/nsp6108F108LTttCtt12B.1.1770.000013
ORF1ab/nsp6108F108LttTttG22B.1.2210.000142
ORF1ab/nsp6108F108LttTttG22B.1.258.140.001961
ORF1ab/nsp6108F108LTttCtt22B.1.4620.014493
ORF1ab/nsp6108F108LttTttG11A.280.002646
ORF1ab/nsp6108F108LttTttG11AV.10.005051
ORF1ab/nsp6108F108LTttCtt11AY.1030.000006
ORF1ab/nsp6108F108LTttCtt11AY.230.00007
ORF1ab/nsp6108F108LTttCtt11AY.250.000006
ORF1ab/nsp6108F108LTttCtt11AY.30.00001
ORF1ab/nsp6108F108LttTttG11AY.39.10.00004
ORF1ab/nsp6108F108LttTttG11AY.440.000006
ORF1ab/nsp6108F108LttTttG11AY.590.00053
ORF1ab/nsp6108F108LttTttG11AY.75.10.00018
ORF1ab/nsp6108F108LttTttG11B.1.1.4090.002833
ORF1ab/nsp6108F108LttTttG11B.1.1.4200.001006
ORF1ab/nsp6108F108LTttCtt11B.1.1.700.000341
ORF1ab/nsp6108F108LttTttG11B.1.2370.004975
ORF1ab/nsp6108F108LttTttA11B.1.264.10.047619
ORF1ab/nsp6108F108LttTttG11B.1.6200.000946
ORF1ab/nsp6108F108LttTttG11B.1.6340.003425
ORF1ab/nsp6108F108LttTttG11C.36.30.000567
ORF1ab/nsp6108F108LttTttG11C.390.018868
ORF1ab/nsp6108F108LttTttG11P.1.110.010204
ORF1ab/nsp6108F108LttTttG11P.1.130.000898
ORF1ab/nsp6108F108LttTttG11P.1.160.000374
ORF1ab/nsp6108F108LttTttG11P.1.17.10.000875
ORF1ab/nsp6108F108LttTttG11Q.60.006623

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.