CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp6 : CodonNum = 82

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp682N82SN3651SnonsynaAtaGt8208190.9987811216-11218
ORF1ab/nsp682N82SN3651SnonsynAAtTCt82010.0012195111216-11218
ORF1ab/nsp682N82NN3651NsynaaTaaC333333111216-11218
ORF1ab/nsp682N82DN3651DnonsynAatGat2323111216-11218
ORF1ab/nsp682N82delN3651deldelAAT---2020111216-11218
ORF1ab/nsp682N82YN3651YnonsynAatTat66111216-11218
ORF1ab/nsp682N82IN3651InonsynaAtaTt66111216-11218
ORF1ab/nsp682N82FN3651FnonsynAAtTTt33111216-11218
ORF1ab/nsp682N82TN3651TnonsynaAtaCt33111216-11218
ORF1ab/nsp682N82KN3651KnonsynaaTaaA33111216-11218
ORF1ab/nsp682N82del1N3651del1delAat-at22111216-11218
ORF1ab/nsp682N82XN3651XnonsynAaTTaG11111216-11218

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp682N82SaAtaGt819820All0.000157
ORF1ab/nsp682N82SAAtTCt1820All0
ORF1ab/nsp682N82SaAtaGt597597A.270.988411
ORF1ab/nsp682N82NaaTaaC333333All0.000064
ORF1ab/nsp682N82SaAtaGt128128B.1.415.10.969697
ORF1ab/nsp682N82NaaTaaC5353B.1.1.70.000047
ORF1ab/nsp682N82NaaTaaC5252B.1.617.20.000196
ORF1ab/nsp682N82NaaTaaC4343B.1.20.000379
ORF1ab/nsp682N82NaaTaaC3838AY.250.000229
ORF1ab/nsp682N82NaaTaaC2626AY.40.00004
ORF1ab/nsp682N82SaAtaGt2424B.1.10.000435
ORF1ab/nsp682N82DAatGat2323All0.000004
ORF1ab/nsp682N82SaAtaGt2020A0.00774
ORF1ab/nsp682N82delAAT---2020All0.000004
ORF1ab/nsp682N82NaaTaaC1919AY.430.000084
ORF1ab/nsp682N82NaaTaaC1919AY.440.000116
ORF1ab/nsp682N82SaAtaGt1515B.10.000137
ORF1ab/nsp682N82SaAtaGt88B0.001022
ORF1ab/nsp682N82YAatTat66All0.000001
ORF1ab/nsp682N82IaAtaTt66All0.000001
ORF1ab/nsp682N82DAatGat66AY.1180.000376
ORF1ab/nsp682N82NaaTaaC66AY.330.000401
ORF1ab/nsp682N82NaaTaaC55B.1.1.250.002843
ORF1ab/nsp682N82delAAT---55B.1.1.70.000004
ORF1ab/nsp682N82DAatGat55B.1.1.70.000004
ORF1ab/nsp682N82SaAtaGt55B.1.2430.000348
ORF1ab/nsp682N82NaaTaaC55R.10.00045
ORF1ab/nsp682N82IaAtaTt440.222222
ORF1ab/nsp682N82NaaTaaC44AY.390.000099
ORF1ab/nsp682N82NaaTaaC44B.10.000037
ORF1ab/nsp682N82NaaTaaC44B.1.10.000073
ORF1ab/nsp682N82YAatTat330.166667
ORF1ab/nsp682N82SaAtaGt33A.290.015957
ORF1ab/nsp682N82KaaTaaA33All0.000001
ORF1ab/nsp682N82FAAtTTt33All0.000001
ORF1ab/nsp682N82TaAtaCt33All0.000001
ORF1ab/nsp682N82NaaTaaC33AY.1030.000019
ORF1ab/nsp682N82SaAtaGt33B.1.1.70.000003
ORF1ab/nsp682N82NaaTaaC33P.10.000047
ORF1ab/nsp682N82FAAtTTt220.111111
ORF1ab/nsp682N82del1Aat-at22All0
ORF1ab/nsp682N82DAatGat22AY.1000.000092
ORF1ab/nsp682N82NaaTaaC22AY.1020.000053
ORF1ab/nsp682N82NaaTaaC22AY.1200.000074
ORF1ab/nsp682N82NaaTaaC22AY.260.000057
ORF1ab/nsp682N82NaaTaaC22AY.300.000791
ORF1ab/nsp682N82NaaTaaC22AY.450.000243
ORF1ab/nsp682N82NaaTaaC22AY.610.00021
ORF1ab/nsp682N82NaaTaaC22AY.99.20.000184
ORF1ab/nsp682N82SaAtaGt22B.1.1.1610.007067
ORF1ab/nsp682N82NaaTaaC22B.1.1280.001271
ORF1ab/nsp682N82DAatGat22B.1.2210.000142
ORF1ab/nsp682N82TaAtaCt22B.1.2580.000133
ORF1ab/nsp682N82NaaTaaC22B.1.4290.000047
ORF1ab/nsp682N82SaAtaGt22B.1.5760.001813
ORF1ab/nsp682N82delAAT---22B.1.617.20.000008
ORF1ab/nsp682N82DAatGat22N.50.003534
ORF1ab/nsp682N82NaaTaaC22P.1.140.000096
ORF1ab/nsp682N82TaAtaCt110.055556
ORF1ab/nsp682N82SAAtTCt110.055556
ORF1ab/nsp682N82SaAtaGt11A.10.000282
ORF1ab/nsp682N82SaAtaGt11A.20.000662
ORF1ab/nsp682N82XAaTTaG11All0
ORF1ab/nsp682N82NaaTaaC11AY.1010.00049
ORF1ab/nsp682N82NaaTaaC11AY.1050.000643
ORF1ab/nsp682N82NaaTaaC11AY.1170.000085
ORF1ab/nsp682N82delAAT---11AY.250.000006
ORF1ab/nsp682N82XAaTTaG11AY.30.00001
ORF1ab/nsp682N82DAatGat11AY.30.00001
ORF1ab/nsp682N82SaAtaGt11AY.30.00001
ORF1ab/nsp682N82YAatTat11AY.40.000002
ORF1ab/nsp682N82DAatGat11AY.40.000002
ORF1ab/nsp682N82delAAT---11AY.40.000002
ORF1ab/nsp682N82NaaTaaC11AY.4.20.000022
ORF1ab/nsp682N82YAatTat11AY.4.20.000022
ORF1ab/nsp682N82delAAT---11AY.420.00004
ORF1ab/nsp682N82NaaTaaC11AY.420.00004
ORF1ab/nsp682N82delAAT---11AY.430.000004
ORF1ab/nsp682N82DAatGat11AY.430.000004
ORF1ab/nsp682N82NaaTaaC11AY.460.000104
ORF1ab/nsp682N82DAatGat11AY.46.60.000072
ORF1ab/nsp682N82NaaTaaC11AY.50.000021
ORF1ab/nsp682N82NaaTaaC11AY.650.000533
ORF1ab/nsp682N82NaaTaaC11AY.710.000475
ORF1ab/nsp682N82delAAT---11AY.710.000475
ORF1ab/nsp682N82delAAT---11AY.750.000056
ORF1ab/nsp682N82NaaTaaC11AY.750.000056
ORF1ab/nsp682N82NaaTaaC11AY.9.20.000037
ORF1ab/nsp682N82NaaTaaC11AY.990.001049
ORF1ab/nsp682N82delAAT---11B.10.000009
ORF1ab/nsp682N82NaaTaaC11B.1.1.1410.002012
ORF1ab/nsp682N82delAAT---11B.1.1.2140.000055
ORF1ab/nsp682N82NaaTaaC11B.1.1.2140.000055
ORF1ab/nsp682N82NaaTaaC11B.1.1.2210.010101
ORF1ab/nsp682N82SaAtaGt11B.1.1.280.000311
ORF1ab/nsp682N82NaaTaaC11B.1.1.3060.000438
ORF1ab/nsp682N82SaAtaGt11B.1.1.3070.002532
ORF1ab/nsp682N82SaAtaGt11B.1.1.330.000421
ORF1ab/nsp682N82SaAtaGt11B.1.1.4090.002833
ORF1ab/nsp682N82NaaTaaC11B.1.1.4320.001266
ORF1ab/nsp682N82NaaTaaC11B.1.1.5190.00004
ORF1ab/nsp682N82del1Aat-at11B.1.1.70.000001
ORF1ab/nsp682N82KaaTaaA11B.1.1.70.000001
ORF1ab/nsp682N82IaAtaTt11B.1.1.70.000001
ORF1ab/nsp682N82NaaTaaC11B.1.1.700.000341
ORF1ab/nsp682N82NaaTaaC11B.1.1600.000031
ORF1ab/nsp682N82SaAtaGt11B.1.160.330.004425
ORF1ab/nsp682N82NaaTaaC11B.1.1770.000013
ORF1ab/nsp682N82KaaTaaA11B.1.1770.000013
ORF1ab/nsp682N82delAAT---11B.1.177.40.000211
ORF1ab/nsp682N82NaaTaaC11B.1.177.730.000566
ORF1ab/nsp682N82SaAtaGt11B.1.177.730.000566
ORF1ab/nsp682N82delAAT---11B.1.177.760.002494
ORF1ab/nsp682N82del1Aat-at11B.1.2060.000816
ORF1ab/nsp682N82NaaTaaC11B.1.36.290.000517
ORF1ab/nsp682N82NaaTaaC11B.1.5250.000113
ORF1ab/nsp682N82IaAtaTt11B.1.5760.000907
ORF1ab/nsp682N82FAAtTTt11B.1.5760.000907
ORF1ab/nsp682N82YAatTat11B.1.5760.000907
ORF1ab/nsp682N82KaaTaaA11B.1.617.20.000004
ORF1ab/nsp682N82DAatGat11B.1.617.20.000004
ORF1ab/nsp682N82NaaTaaC11B.1.6210.000089
ORF1ab/nsp682N82SaAtaGt11B.1.6230.000536
ORF1ab/nsp682N82SaAtaGt11B.550.00295
ORF1ab/nsp682N82NaaTaaC11C.360.000911
ORF1ab/nsp682N82NaaTaaC11C.370.000116
ORF1ab/nsp682N82SaAtaGt11C.60.037037
ORF1ab/nsp682N82NaaTaaC11D.20.000075
ORF1ab/nsp682N82delAAT---11N.40.004255
ORF1ab/nsp682N82DAatGat11P.1.140.000048
ORF1ab/nsp682N82delAAT---11P.1.150.000232
ORF1ab/nsp682N82delAAT---11Q.80.000165
ORF1ab/nsp682N82NaaTaaC11W.30.005263

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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