CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp6 : CodonNum = 110

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp6110L110LL3679LsynCtaTta261524630.94187411300-11302
ORF1ab/nsp6110L110LL3679LsynctActG26151010.038623311300-11302
ORF1ab/nsp6110L110LL3679LsynctActT2615360.013766711300-11302
ORF1ab/nsp6110L110LL3679LsynctActC2615150.0057361411300-11302
ORF1ab/nsp6110L110IL3679InonsynCtaAta43410.95348811300-11302
ORF1ab/nsp6110L110IL3679InonsynCtAAtT4320.046511611300-11302
ORF1ab/nsp6110L110delL3679deldelCTA---3636111300-11302
ORF1ab/nsp6110L110YL3679YnonsynCTATAC2121111300-11302
ORF1ab/nsp6110L110PL3679PnonsyncTacCa2121111300-11302
ORF1ab/nsp6110L110QL3679QnonsyncTacAa1212111300-11302
ORF1ab/nsp6110L110del1L3679del1delctAct-12100.83333311300-11302
ORF1ab/nsp6110L110del1L3679del1delcTac-a1210.083333311300-11302
ORF1ab/nsp6110L110del1L3679del1delCta-ta1210.083333311300-11302
ORF1ab/nsp6110L110VL3679VnonsynCtaGta970.77777811300-11302
ORF1ab/nsp6110L110VL3679VnonsynCtAGtT920.22222211300-11302
ORF1ab/nsp6110L110RL3679RnonsyncTAcGT840.511300-11302
ORF1ab/nsp6110L110RL3679RnonsyncTacGa840.511300-11302
ORF1ab/nsp6110L110FL3679FnonsynCtATtT33111300-11302
ORF1ab/nsp6110L110XL3679XnonsynCTaTGa33111300-11302
ORF1ab/nsp6110L110CL3679CnonsynCTATGT33111300-11302
ORF1ab/nsp6110L110GL3679GnonsynCTAGGT210.511300-11302
ORF1ab/nsp6110L110GL3679GnonsynCTaGGa210.511300-11302
ORF1ab/nsp6110L110SL3679SnonsynCTAAGC210.511300-11302
ORF1ab/nsp6110L110SL3679SnonsynCTaTCa210.511300-11302
ORF1ab/nsp6110L110AL3679AnonsynCTAGCC11111300-11302
ORF1ab/nsp6110L110del2L3679del2delcTAc--11111300-11302
ORF1ab/nsp6110L110TL3679TnonsynCTaACa11111300-11302
ORF1ab/nsp6110L110NL3679NnonsynCTAAAT11111300-11302
ORF1ab/nsp6110L110KL3679KnonsynCTaAAa11111300-11302

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp6110L110LCtaTta24632615All0.000471
ORF1ab/nsp6110L110LctActG1012615All0.000019
ORF1ab/nsp6110L110LctActT362615All0.000007
ORF1ab/nsp6110L110LctActC152615All0.000003
ORF1ab/nsp6110L110LCtaTta16161679B.1.1.70.001447
ORF1ab/nsp6110L110LctActG621679B.1.1.70.000056
ORF1ab/nsp6110L110LctActT11679B.1.1.70.000001
ORF1ab/nsp6110L110LCtaTta130130B.1.10.002358
ORF1ab/nsp6110L110LCtaTta7175AY.440.000432
ORF1ab/nsp6110L110LctActT275AY.440.000012
ORF1ab/nsp6110L110LctActG275AY.440.000012
ORF1ab/nsp6110L110LCtaTta5757B.1.1.5190.002264
ORF1ab/nsp6110L110LCtaTta5254AY.430.00023
ORF1ab/nsp6110L110LctActT254AY.430.000009
ORF1ab/nsp6110L110LCtaTta5354B.1.20.000467
ORF1ab/nsp6110L110LctActG154B.1.20.000009
ORF1ab/nsp6110L110ICtaAta4143All0.000008
ORF1ab/nsp6110L110ICtAAtT243All0
ORF1ab/nsp6110L110LCtaTta4042AY.50.000826
ORF1ab/nsp6110L110LctActG242AY.50.000041
ORF1ab/nsp6110L110LCtaTta2540AY.40.000039
ORF1ab/nsp6110L110LctActG1540AY.40.000023
ORF1ab/nsp6110L110LCtaTta3639B.1.617.20.000136
ORF1ab/nsp6110L110LctActT239B.1.617.20.000008
ORF1ab/nsp6110L110LctActG139B.1.617.20.000004
ORF1ab/nsp6110L110delCTA---3636All0.000007
ORF1ab/nsp6110L110LCtaTta3636AY.1030.000224
ORF1ab/nsp6110L110LCtaTta3030P.1.170.004853
ORF1ab/nsp6110L110LctActC1428B.10.000128
ORF1ab/nsp6110L110LCtaTta1228B.10.00011
ORF1ab/nsp6110L110LctActG128B.10.000009
ORF1ab/nsp6110L110LctActT128B.10.000009
ORF1ab/nsp6110L110LCtaTta2323AY.30.000229
ORF1ab/nsp6110L110YCTATAC2121All0.000004
ORF1ab/nsp6110L110PcTacCa2121All0.000004
ORF1ab/nsp6110L110LCtaTta1921P.10.000299
ORF1ab/nsp6110L110LctActT221P.10.000032
ORF1ab/nsp6110L110LCtaTta1818B.1.1.280.005602
ORF1ab/nsp6110L110YCTATAC1818B.1.351.10.692308
ORF1ab/nsp6110L110LCtaTta1415AY.1200.000521
ORF1ab/nsp6110L110LctActG115AY.1200.000037
ORF1ab/nsp6110L110delCTA---1515B.1.351.30.013146
ORF1ab/nsp6110L110LCtaTta1314AY.1210.001759
ORF1ab/nsp6110L110LctActT114AY.1210.000135
ORF1ab/nsp6110L110LCtaTta1213AY.250.000072
ORF1ab/nsp6110L110LctActT113AY.250.000006
ORF1ab/nsp6110L110LCtaTta1313B.1.1600.000405
ORF1ab/nsp6110L110LCtaTta1313B.1.617.10.001677
ORF1ab/nsp6110L110QcTacAa1212All0.000002
ORF1ab/nsp6110L110del1ctAct-1012All0.000002
ORF1ab/nsp6110L110del1Cta-ta112All0
ORF1ab/nsp6110L110del1cTac-a112All0
ORF1ab/nsp6110L110LctActT1212AY.910.008766
ORF1ab/nsp6110L110LCtaTta1112B.1.1770.000145
ORF1ab/nsp6110L110LctActG112B.1.1770.000013
ORF1ab/nsp6110L110LCtaTta1112B.1.3510.000327
ORF1ab/nsp6110L110LctActC112B.1.3510.00003
ORF1ab/nsp6110L110ICtaAta1111B.1.20.000097
ORF1ab/nsp6110L110LCtaTta1111B.1.5260.000259
ORF1ab/nsp6110L110VCtaGta79All0.000001
ORF1ab/nsp6110L110VCtAGtT29All0
ORF1ab/nsp6110L110LctActT89B.1.1.3170.003294
ORF1ab/nsp6110L110LCtaTta19B.1.1.3170.000412
ORF1ab/nsp6110L110LCtaTta99B.1.177.570.002529
ORF1ab/nsp6110L110LCtaTta99B.1.5960.000784
ORF1ab/nsp6110L110RcTacGa48All0.000001
ORF1ab/nsp6110L110RcTAcGT48All0.000001
ORF1ab/nsp6110L110LCtaTta88B.1.1.2140.000444
ORF1ab/nsp6110L110LCtaTta47AY.390.000099
ORF1ab/nsp6110L110LctActG37AY.390.000074
ORF1ab/nsp6110L110ICtaAta77AY.440.000043
ORF1ab/nsp6110L110PcTacCa66B.1.1.70.000005
ORF1ab/nsp6110L110delCTA---66B.1.1.70.000005
ORF1ab/nsp6110L110VCtaGta56B.1.1.70.000004
ORF1ab/nsp6110L110VCtAGtT16B.1.1.70.000001
ORF1ab/nsp6110L110LCtaTta66Q.10.000758
ORF1ab/nsp6110L110LCtaTta55AY.300.001979
ORF1ab/nsp6110L110ICtaAta45B.1.1.70.000004
ORF1ab/nsp6110L110ICtAAtT15B.1.1.70.000001
ORF1ab/nsp6110L110LCtaTta34B.1.438.10.000322
ORF1ab/nsp6110L110LctActG14B.1.438.10.000107
ORF1ab/nsp6110L110RcTacGa24P.10.000032
ORF1ab/nsp6110L110RcTAcGT24P.10.000032
ORF1ab/nsp6110L110LCtaTta33A0.001161
ORF1ab/nsp6110L110CCTATGT33All0.000001
ORF1ab/nsp6110L110XCTaTGa33All0.000001
ORF1ab/nsp6110L110FCtATtT33All0.000001
ORF1ab/nsp6110L110ICtaAta33AY.200.000117
ORF1ab/nsp6110L110QcTacAa33AY.430.000013
ORF1ab/nsp6110L110ICtaAta33AY.430.000013
ORF1ab/nsp6110L110LctActG33AY.590.001589
ORF1ab/nsp6110L110LCtaTta33B.1.1.3760.017857
ORF1ab/nsp6110L110del1ctAct-23B.1.1.70.000002
ORF1ab/nsp6110L110del1Cta-ta13B.1.1.70.000001
ORF1ab/nsp6110L110ICtaAta33B.1.1770.00004
ORF1ab/nsp6110L110delCTA---33B.1.3510.000089
ORF1ab/nsp6110L110delCTA---33B.1.5250.000339
ORF1ab/nsp6110L110ICtaAta33B.1.617.20.000011
ORF1ab/nsp6110L110LCtaTta33B.1.6210.000266
ORF1ab/nsp6110L110LCtaTta33B.1.6370.000219
ORF1ab/nsp6110L110LCtaTta23P.1.140.000096
ORF1ab/nsp6110L110LctActT13P.1.140.000048
ORF1ab/nsp6110L110RcTAcGT120.055556
ORF1ab/nsp6110L110VCtaGta120.055556
ORF1ab/nsp6110L110VCtAGtT120.055556
ORF1ab/nsp6110L110GCTAGGT120.055556
ORF1ab/nsp6110L110RcTacGa120.055556
ORF1ab/nsp6110L110GCTaGGa120.055556
ORF1ab/nsp6110L110SCTAAGC12All0
ORF1ab/nsp6110L110SCTaTCa12All0
ORF1ab/nsp6110L110GCTAGGT12All0
ORF1ab/nsp6110L110GCTaGGa12All0
ORF1ab/nsp6110L110LCtaTta12AY.1020.000027
ORF1ab/nsp6110L110LctActT12AY.1020.000027
ORF1ab/nsp6110L110delCTA---22AY.250.000012
ORF1ab/nsp6110L110LCtaTta22AY.260.000057
ORF1ab/nsp6110L110LCtaTta22AY.290.000032
ORF1ab/nsp6110L110LCtaTta22AY.39.10.000079
ORF1ab/nsp6110L110LCtaTta22AY.470.000062
ORF1ab/nsp6110L110LCtaTta22AY.680.000547
ORF1ab/nsp6110L110LCtaTta22AY.700.000417
ORF1ab/nsp6110L110LCtaTta12AY.98.10.000048
ORF1ab/nsp6110L110LctActG12AY.98.10.000048
ORF1ab/nsp6110L110LctActG12B0.000128
ORF1ab/nsp6110L110LCtaTta12B0.000128
ORF1ab/nsp6110L110PcTacCa22B.10.000018
ORF1ab/nsp6110L110ICtaAta12B.10.000009
ORF1ab/nsp6110L110ICtAAtT12B.10.000009
ORF1ab/nsp6110L110ICtaAta22B.1.1.1590.009346
ORF1ab/nsp6110L110LCtaTta22B.1.1.1610.007067
ORF1ab/nsp6110L110LctActG22B.1.1.1890.003026
ORF1ab/nsp6110L110LCtaTta22B.1.1.2840.000215
ORF1ab/nsp6110L110LctActG12B.1.1.4340.000349
ORF1ab/nsp6110L110LCtaTta12B.1.1.4340.000349
ORF1ab/nsp6110L110LCtaTta22B.1.177.830.002963
ORF1ab/nsp6110L110QcTacAa22B.1.20.000018
ORF1ab/nsp6110L110LCtaTta22B.1.2330.028169
ORF1ab/nsp6110L110LCtaTta22B.1.2580.000133
ORF1ab/nsp6110L110YCTATAC22B.1.3510.000059
ORF1ab/nsp6110L110LCtaTta22B.1.360.000292
ORF1ab/nsp6110L110LCtaTta22B.1.4270.000101
ORF1ab/nsp6110L110LCtaTta22B.1.4290.000047
ORF1ab/nsp6110L110PcTacCa22B.1.617.20.000008
ORF1ab/nsp6110L110PcTacCa22B.1.6210.000177
ORF1ab/nsp6110L110LCtaTta22C.370.000232
ORF1ab/nsp6110L110XCTaTGa22P.10.000032
ORF1ab/nsp6110L110CCTATGT22P.10.000032
ORF1ab/nsp6110L110FCtATtT22P.10.000032
ORF1ab/nsp6110L110LCtaTta22P.1.100.000539
ORF1ab/nsp6110L110RcTacGa12P.1.140.000048
ORF1ab/nsp6110L110RcTAcGT12P.1.140.000048
ORF1ab/nsp6110L110LCtaTta22Q.40.00091
ORF1ab/nsp6110L110LctActT110.055556
ORF1ab/nsp6110L110LCtaTta11A.20.000662
ORF1ab/nsp6110L110LCtaTta11AH.30.003802
ORF1ab/nsp6110L110del2cTAc--11All0
ORF1ab/nsp6110L110TCTaACa11All0
ORF1ab/nsp6110L110NCTAAAT11All0
ORF1ab/nsp6110L110KCTaAAa11All0
ORF1ab/nsp6110L110ACTAGCC11All0
ORF1ab/nsp6110L110LCtaTta11AY.1000.000046
ORF1ab/nsp6110L110PcTacCa11AY.1000.000046
ORF1ab/nsp6110L110LCtaTta11AY.1080.001103
ORF1ab/nsp6110L110LCtaTta11AY.1170.000085
ORF1ab/nsp6110L110del1ctAct-11AY.1190.000035
ORF1ab/nsp6110L110LctActG11AY.1190.000035
ORF1ab/nsp6110L110LCtaTta11AY.120.000316
ORF1ab/nsp6110L110LCtaTta11AY.16.10.00047
ORF1ab/nsp6110L110LCtaTta11AY.200.000039
ORF1ab/nsp6110L110ICtaAta11AY.290.000016
ORF1ab/nsp6110L110PcTacCa11AY.290.000016
ORF1ab/nsp6110L110LCtaTta11AY.3.10.000085
ORF1ab/nsp6110L110ICtaAta11AY.300.000396
ORF1ab/nsp6110L110QcTacAa11AY.390.000025
ORF1ab/nsp6110L110QcTacAa11AY.40.000002
ORF1ab/nsp6110L110delCTA---11AY.40.000002
ORF1ab/nsp6110L110LCtaTta11AY.4.20.000022
ORF1ab/nsp6110L110LCtaTta11AY.4.40.000409
ORF1ab/nsp6110L110LCtaTta11AY.420.00004
ORF1ab/nsp6110L110del1ctAct-11AY.440.000006
ORF1ab/nsp6110L110PcTacCa11AY.440.000006
ORF1ab/nsp6110L110PcTacCa11AY.460.000104
ORF1ab/nsp6110L110PcTacCa11AY.50.000021
ORF1ab/nsp6110L110LCtaTta11AY.530.000288
ORF1ab/nsp6110L110LCtaTta11AY.60.000041
ORF1ab/nsp6110L110LCtaTta11AY.620.000436
ORF1ab/nsp6110L110del1ctAct-11AY.670.000464
ORF1ab/nsp6110L110LCtaTta11AY.7.10.000113
ORF1ab/nsp6110L110LCtaTta11AY.710.000475
ORF1ab/nsp6110L110LCtaTta11AY.750.000056
ORF1ab/nsp6110L110LCtaTta11AY.780.001541
ORF1ab/nsp6110L110delCTA---11AY.780.001541
ORF1ab/nsp6110L110LCtaTta11AY.840.000437
ORF1ab/nsp6110L110SCTaTCa11AY.960.002075
ORF1ab/nsp6110L110PcTacCa11B0.000128
ORF1ab/nsp6110L110ACTAGCC11B.10.000009
ORF1ab/nsp6110L110delCTA---11B.10.000009
ORF1ab/nsp6110L110delCTA---11B.1.10.000018
ORF1ab/nsp6110L110ICtaAta11B.1.10.000018
ORF1ab/nsp6110L110del1ctAct-11B.1.10.000018
ORF1ab/nsp6110L110LCtaTta11B.1.1.2770.000759
ORF1ab/nsp6110L110LCtaTta11B.1.1.3010.001179
ORF1ab/nsp6110L110QcTacAa11B.1.1.3060.000438
ORF1ab/nsp6110L110delCTA---11B.1.1.3180.000302
ORF1ab/nsp6110L110LCtaTta11B.1.1.3180.000302
ORF1ab/nsp6110L110LCtaTta11B.1.1.3360.016667
ORF1ab/nsp6110L110LCtaTta11B.1.1.3480.000796
ORF1ab/nsp6110L110LCtaTta11B.1.1.3690.000446
ORF1ab/nsp6110L110LctActT11B.1.1.3710.010417
ORF1ab/nsp6110L110LCtaTta11B.1.1.3720.000689
ORF1ab/nsp6110L110LCtaTta11B.1.1.4130.006897
ORF1ab/nsp6110L110LCtaTta11B.1.1.4320.001266
ORF1ab/nsp6110L110LCtaTta11B.1.1.5180.006329
ORF1ab/nsp6110L110KCTaAAa11B.1.1.70.000001
ORF1ab/nsp6110L110TCTaACa11B.1.1.70.000001
ORF1ab/nsp6110L110NCTAAAT11B.1.1.70.000001
ORF1ab/nsp6110L110SCTAAGC11B.1.1.70.000001
ORF1ab/nsp6110L110del2cTAc--11B.1.1.70.000001
ORF1ab/nsp6110L110PcTacCa11B.1.1.700.000341
ORF1ab/nsp6110L110QcTacAa11B.1.1.830.00271
ORF1ab/nsp6110L110LCtaTta11B.1.1460.004237
ORF1ab/nsp6110L110del1ctAct-11B.1.1600.000031
ORF1ab/nsp6110L110LCtaTta11B.1.160.330.004425
ORF1ab/nsp6110L110PcTacCa11B.1.1770.000013
ORF1ab/nsp6110L110LCtaTta11B.1.177.210.000076
ORF1ab/nsp6110L110LCtaTta11B.1.177.240.001295
ORF1ab/nsp6110L110LCtaTta11B.1.177.870.000728
ORF1ab/nsp6110L110LCtaTta11B.1.2210.000071
ORF1ab/nsp6110L110LCtaTta11B.1.2400.000216
ORF1ab/nsp6110L110LCtaTta11B.1.258.140.00098
ORF1ab/nsp6110L110LCtaTta11B.1.3240.001605
ORF1ab/nsp6110L110LctActG11B.1.3380.008621
ORF1ab/nsp6110L110ICtaAta11B.1.3490.000715
ORF1ab/nsp6110L110LCtaTta11B.1.36.20.010753
ORF1ab/nsp6110L110LctActG11B.1.3690.000285
ORF1ab/nsp6110L110del1ctAct-11B.1.3720.010989
ORF1ab/nsp6110L110QcTacAa11B.1.4130.004255
ORF1ab/nsp6110L110PcTacCa11B.1.4290.000024
ORF1ab/nsp6110L110LCtaTta11B.1.4590.004082
ORF1ab/nsp6110L110LCtaTta11B.1.4700.001404
ORF1ab/nsp6110L110LCtaTta11B.1.4990.00105
ORF1ab/nsp6110L110LCtaTta11B.1.5170.000427
ORF1ab/nsp6110L110YCTATAC11B.1.5240.001406
ORF1ab/nsp6110L110LCtaTta11B.1.5250.000113
ORF1ab/nsp6110L110LCtaTta11B.1.5280.047619
ORF1ab/nsp6110L110LCtaTta11B.1.5750.000303
ORF1ab/nsp6110L110LCtaTta11B.1.5950.000261
ORF1ab/nsp6110L110del1ctAct-11B.1.5960.000087
ORF1ab/nsp6110L110del1cTac-a11B.1.617.10.000129
ORF1ab/nsp6110L110del1ctAct-11B.1.617.20.000004
ORF1ab/nsp6110L110delCTA---11B.1.6300.005236
ORF1ab/nsp6110L110QcTacAa11C.350.000774
ORF1ab/nsp6110L110QcTacAa11D.20.000075
ORF1ab/nsp6110L110delCTA---11N.40.004255
ORF1ab/nsp6110L110CCTATGT11P.1.140.000048
ORF1ab/nsp6110L110XCTaTGa11P.1.140.000048
ORF1ab/nsp6110L110FCtATtT11P.1.140.000048
ORF1ab/nsp6110L110VCtaGta11P.1.20.001156
ORF1ab/nsp6110L110LCtaTta11P.1.30.034483
ORF1ab/nsp6110L110LCtaTta11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.