CoV-GLUE | Mutations | Mutation
CoV-GLUE Mutation: ORF = ORF1ab/nsp5A-B : Mut = V247F
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
| ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
| ORF1ab/nsp5A-B | 247 | V247F | V3510F | nonsyn | Gtt | Ttt | 2089 | 2089 | 1 | 10793-10795 |
Details of the mutation V247F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
| ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2089 | 2089 | All | 0.0004 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 487 | 487 | B.1 | 0.004461 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 450 | 450 | B.1.127 | 0.989011 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 410 | 410 | AY.103 | 0.002546 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 113 | 113 | AD.2 | 0.024743 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 52 | 52 | B.1.468 | 0.297143 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 45 | 45 | AY.25 | 0.000271 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 44 | 44 | B.1.1.214 | 0.00244 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 44 | 44 | B.1.617.2 | 0.000166 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 42 | 42 | AY.43 | 0.000186 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 41 | 41 | B.1.163 | 1 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 39 | 39 | AY.44 | 0.000237 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 28 | 28 | AY.102 | 0.000742 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 27 | 27 | B.1.396 | 0.019054 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 26 | 26 | B.1.2 | 0.000229 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 23 | 23 | B.1.1.7 | 0.000021 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 18 | 18 | AY.4 | 0.000028 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 17 | 17 | B.1.177 | 0.000224 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 9 | 9 | AY.33 | 0.000601 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 8 | 8 | B.1.1 | 0.000145 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 8 | 8 | D.2 | 0.0006 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 7 | 7 | AY.46 | 0.000729 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 7 | 7 | AY.85 | 0.00299 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 7 | 7 | B.1.280 | 0.05 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 7 | 7 | B.1.429 | 0.000165 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 6 | 6 | AY.3 | 0.00006 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 6 | 6 | B.1.1.170 | 0.007481 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 6 | 6 | P.1 | 0.000095 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 5 | 5 | AY.110 | 0.000563 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 5 | 5 | AY.4.2 | 0.000108 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 5 | 5 | B.1.1.519 | 0.000199 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 4 | 4 | AY.42 | 0.000161 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 4 | 4 | B.1.596 | 0.000349 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 3 | 3 | AY.100 | 0.000138 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 3 | 3 | AY.109 | 0.002219 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 3 | 3 | AY.20 | 0.000117 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 3 | 3 | AY.39 | 0.000074 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 3 | 3 | AY.9 | 0.000203 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 3 | 3 | B.1.375 | 0.002459 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | A.2.5 | 0.000998 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | AY.24 | 0.000862 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | AY.26 | 0.000057 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | AY.6 | 0.000082 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | AY.61 | 0.00021 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | AY.64 | 0.00119 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | B | 0.000256 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | B.1.1.25 | 0.001137 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | B.1.1.274 | 0.010101 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | B.1.1.277 | 0.001517 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | B.1.1.318 | 0.000604 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | B.1.177.12 | 0.000303 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | B.1.177.75 | 0.002081 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | B.1.243 | 0.000139 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | B.1.466.2 | 0.000782 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 2 | 2 | B.40 | 0.000729 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | AY.107 | 0.000466 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | AY.117 | 0.000085 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | AY.121 | 0.000135 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | AY.3.1 | 0.000085 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | AY.47 | 0.000031 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | AY.5.3 | 0.000337 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | AY.53 | 0.000288 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | AY.69 | 0.000187 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | AY.91 | 0.00073 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | AY.99 | 0.001049 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.1.1 | 0.000327 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.1.307 | 0.002532 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.1.47 | 0.005348 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.1.525 | 0.005464 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.111 | 0.001175 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.160 | 0.000031 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.177.7 | 0.000165 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.177.79 | 0.002342 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.177.88 | 0.012346 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.214.2 | 0.0006 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.221 | 0.000071 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.239 | 0.001221 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.240 | 0.000216 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.248 | 0.029412 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.324 | 0.001605 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.351 | 0.00003 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.36.22 | 0.001208 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.427 | 0.00005 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.456 | 0.003268 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.470 | 0.001404 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.471 | 0.002732 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.513 | 0.013889 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.546 | 0.003704 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.577 | 0.000687 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.599 | 0.00365 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.621.1 | 0.000506 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.1.93 | 0.000934 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | B.20 | 0.023256 |
| ORF1ab/nsp5A-B | 247 | V247F | Gtt | Ttt | 1 | 1 | R.1 | 0.00009 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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