CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp5A-B : Mut = I249L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp5A-B249I249LI3512LnonsynAtaCta21180.85714310799-10801
ORF1ab/nsp5A-B249I249LI3512LnonsynAtaTta2120.095238110799-10801
ORF1ab/nsp5A-B249I249LI3512LnonsynAtACtC2110.04761910799-10801

Details of the mutation I249L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp5A-B249I249LAtaCta1821All0.000003
ORF1ab/nsp5A-B249I249LAtaTta221All0
ORF1ab/nsp5A-B249I249LAtACtC121All0
ORF1ab/nsp5A-B249I249LAtaCta55B.1.5650.004052
ORF1ab/nsp5A-B249I249LAtaCta44AY.40.000006
ORF1ab/nsp5A-B249I249LAtaCta33B.1.1.370.000579
ORF1ab/nsp5A-B249I249LAtaCta22B.1.1.70.000002
ORF1ab/nsp5A-B249I249LAtaCta22B.1.617.20.000008
ORF1ab/nsp5A-B249I249LAtaCta11AY.390.000025
ORF1ab/nsp5A-B249I249LAtACtC11AY.440.000006
ORF1ab/nsp5A-B249I249LAtaCta11AY.450.000122
ORF1ab/nsp5A-B249I249LAtaTta11AY.990.001049
ORF1ab/nsp5A-B249I249LAtaTta11P.1.140.000048