CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp5A-B : CodonNum = 231 & Codon = aaT

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp5A-B	231	N231N	N3494N	syn	aaC	aaT	7588	7588	1	10745-10747

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	7588	7588	All	0.001451
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1967	1967	B.1.1.7	0.001761
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1368	1368	A.23.1	0.96338
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	687	687	AY.4	0.001069
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	544	544	B.1	0.004983
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	405	405	AY.103	0.002515
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	290	290	B.1.617.2	0.001092
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	259	259	AY.43	0.001147
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	196	196	B.1.88.1	0.942308
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	159	159	B.1.605	0.946429
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	126	126	AY.44	0.000767
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	124	124	B.1.2	0.001092
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	94	94	AY.36	0.013932
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	93	93	A.23	0.978947
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	87	87	B.1.427	0.004393
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	61	61	P.1.14	0.002916
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	58	58	AY.25	0.000349
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	54	54	B.1.179	0.203008
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	50	50	B.1.177	0.000658
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	33	33	AY.3	0.000328
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	33	33	Q.8	0.005442
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	32	32	P.1	0.000504
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	29	29	B.1.1.284	0.003115
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	28	28	B.1.1	0.000508
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	27	27	C.37	0.003134
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	26	26	AY.20	0.00101
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	26	26	AY.39	0.000642
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	26	26	B.1.351	0.000773
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	25	25	B.1.160	0.00078
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	25	25	B.1.526	0.000588
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	24	24	AY.102	0.000636
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	23	23	AY.3.1	0.001961
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	22	22	B.1.1.396	1
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	22	22	B.1.240	0.004742
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	17	17	B.1.36.39	0.037694
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	16	16	AY.47	0.000498
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	16	16	AY.75	0.000896
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	16	16	B.1.1.330	1
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	15	15	B.1.429	0.000353
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	14	14	AY.5	0.000289
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	14	14	B.1.596	0.00122
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	12	12	B.1.177.57	0.003372
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	11	11	B.1.147	0.008314
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	11	11	B.1.436	0.011317
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	10	10	AY.42	0.000402
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	10	10	AY.46	0.001041
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	10	10	AY.69	0.001867
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	10	10	B.1.1.519	0.000397
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	10	10	B.1.177.21	0.000765
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	10	10	B.1.221	0.00071
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	10	10	B.1.36	0.001459
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	9	9	A	0.003483
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	9	9	AY.26	0.000255
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	9	9	AY.29	0.000142
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	9	9	B.1.619.1	0.005773
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	7	7	AY.119	0.000247
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	7	7	B.1.621	0.00062
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	6	6	AY.105	0.003859
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	6	6	AY.116.1	0.001869
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	6	6	AY.117	0.000507
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	6	6	AY.33	0.000401
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	6	6	AY.93	0.001638
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	6	6	B.1.389	0.006012
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	5	5	AY.39.1	0.000198
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	5	5	B	0.000639
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	5	5	B.1.1.409	0.014164
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	5	5	B.1.258	0.000333
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	5	5	B.1.525	0.000566
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	5	5	Q.1	0.000632
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	AY.100	0.000184
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	AY.23	0.000279
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	AY.68	0.001095
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	AY.78	0.006163
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	AY.9	0.00027
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	B.1.1.1	0.001307
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	B.1.1.222	0.000816
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	B.1.177.12	0.000607
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	B.1.177.81	0.000757
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	B.1.243	0.000278
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	B.1.258.3	0.0067
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	B.1.396	0.002823
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	B.1.564	0.001704
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	B.1.617.1	0.000516
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	4	4	P.1.17	0.000647
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	3	3	AY.24	0.001293
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	3	3	AY.34.1	0.00153
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	3	3	AY.54	0.000286
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	3	3	AY.6	0.000123
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	3	3	AY.7	0.000588
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	3	3	AY.7.2	0.001678
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	3	3	B.1.1.354	0.013158
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	3	3	B.1.189	0.012876
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	3	3	B.1.234	0.000396
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	3	3	B.1.258.11	0.001189
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	3	3	B.1.609	0.001438
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	3	3	P.1.15	0.000697
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	A.1	0.000564
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.113	0.000285
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.118	0.000125
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.120	0.000074
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.120.1	0.000642
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.121	0.000271
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.14	0.000176
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.16	0.000759
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.34	0.000194
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.45	0.000243
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.61	0.00021
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.62	0.000871
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.82	0.002714
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.92	0.000575
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.98	0.000158
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	AY.99.2	0.000184
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	B.1.1.10	0.00223
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	B.1.1.374	0.004751
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	B.1.1.39	0.001019
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	B.1.160.32	0.008584
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	B.1.167	0.015625
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	B.1.206	0.001631
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	B.1.232	0.001075
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	B.1.258.17	0.000208
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	B.1.36.31	0.003503
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	B.1.416	0.002538
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	B.1.438.1	0.000215
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	B.1.595	0.000522
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	B.1.623	0.001073
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	B.1.636	0.013423
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	C.36	0.001821
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	P.1.12	0.000968
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	2	2	P.1.2	0.002312
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	A.2.5	0.000499
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	A.27	0.001656
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AD.2	0.000219
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.10	0.00053
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.106	0.000335
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.111	0.000183
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.114	0.000231
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.19	0.00114
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.27	0.000065
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.29.1	0.000221
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.30	0.000396
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.4.2	0.000022
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.46.1	0.001027
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.46.4	0.000165
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.46.5	0.000198
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.5.3	0.000337
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.5.4	0.000277
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.65	0.000533
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.66	0.00107
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.73	0.000665
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.74	0.000116
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.75.1	0.00018
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.85	0.000427
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.91	0.00073
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	AY.98.1	0.000048
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.216	0.00089
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.277	0.000759
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.28	0.000311
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.289	0.002083
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.31	0.066667
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.318	0.000302
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.340	0.045455
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.359	0.027778
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.372	0.000689
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.391	0.008547
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.402	0.011111
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.434	0.000349
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.500	0.02
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.523	0.001563
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.63	0.000386
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.1.70	0.000341
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.115	0.021739
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.143	0.021277
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.146	0.004237
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.157	0.002985
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.160.16	0.000929
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.177.16	0.000664
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.177.41	0.0025
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.177.60	0.000218
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.177.73	0.000566
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.177.8	0.000752
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.177.83	0.001481
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.177.86	0.000183
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.199	0.004132
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.320	0.001245
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.349	0.000715
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.36.18	0.00042
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.369	0.000285
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.382	0.008929
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.480	0.002488
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.499	0.00105
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.503	0.002488
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.545	0.014493
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.575	0.000303
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.582	0.000491
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.596.1	0.009346
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.618	0.004032
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.1.637	0.000073
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	B.6.6	0.000889
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	C.18	0.002591
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	C.8	0.004464
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	K.1	0.02381
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	P.1.10.1	0.00813
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	Q.3	0.000145
ORF1ab/nsp5A-B	231	N231N	aaC	aaT	1	1	R.1	0.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.