CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = Y397Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4397Y397YY3160YsyntaCtaT8615861519743-9745

Details of the mutation Y397Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4397Y397YtaCtaT86158615All0.001648
ORF1ab/nsp4397Y397YtaCtaT35353535B.1.177.570.993257
ORF1ab/nsp4397Y397YtaCtaT16461646B.1.177.540.998181
ORF1ab/nsp4397Y397YtaCtaT14831483B.1.177.560.989987
ORF1ab/nsp4397Y397YtaCtaT427427B.1.177.550.995338
ORF1ab/nsp4397Y397YtaCtaT403403B.1.1.70.000361
ORF1ab/nsp4397Y397YtaCtaT120120B.1.617.20.000452
ORF1ab/nsp4397Y397YtaCtaT115115P.10.001812
ORF1ab/nsp4397Y397YtaCtaT9696AY.430.000425
ORF1ab/nsp4397Y397YtaCtaT8181AY.40.000126
ORF1ab/nsp4397Y397YtaCtaT5858B.1.1770.000764
ORF1ab/nsp4397Y397YtaCtaT5858C.40.58
ORF1ab/nsp4397Y397YtaCtaT4646B.1.1.5190.001827
ORF1ab/nsp4397Y397YtaCtaT4444V.11
ORF1ab/nsp4397Y397YtaCtaT3939B.10.000357
ORF1ab/nsp4397Y397YtaCtaT3636AY.116.10.011211
ORF1ab/nsp4397Y397YtaCtaT3333B.1.5850.916667
ORF1ab/nsp4397Y397YtaCtaT3030V.20.967742
ORF1ab/nsp4397Y397YtaCtaT2626B.1.1.3170.010704
ORF1ab/nsp4397Y397YtaCtaT2121AY.5.40.005811
ORF1ab/nsp4397Y397YtaCtaT1919AY.34.10.009689
ORF1ab/nsp4397Y397YtaCtaT1919B.1.20.000167
ORF1ab/nsp4397Y397YtaCtaT1818AY.1030.000112
ORF1ab/nsp4397Y397YtaCtaT1616B.1.6280.005638
ORF1ab/nsp4397Y397YtaCtaT1414B.1.177.180.016241
ORF1ab/nsp4397Y397YtaCtaT1313AY.390.000321
ORF1ab/nsp4397Y397YtaCtaT1212AY.440.000073
ORF1ab/nsp4397Y397YtaCtaT1212B.1.6370.000877
ORF1ab/nsp4397Y397YtaCtaT1111AY.250.000066
ORF1ab/nsp4397Y397YtaCtaT1111B.1.10.0002
ORF1ab/nsp4397Y397YtaCtaT88B.1.160.160.007435
ORF1ab/nsp4397Y397YtaCtaT77AY.50.000145
ORF1ab/nsp4397Y397YtaCtaT77AY.5.30.002362
ORF1ab/nsp4397Y397YtaCtaT66B.1.3510.000178
ORF1ab/nsp4397Y397YtaCtaT66B.1.5770.004124
ORF1ab/nsp4397Y397YtaCtaT55AY.470.000156
ORF1ab/nsp4397Y397YtaCtaT44AY.260.000113
ORF1ab/nsp4397Y397YtaCtaT44AY.30.00004
ORF1ab/nsp4397Y397YtaCtaT44AY.370.001264
ORF1ab/nsp4397Y397YtaCtaT44AY.99.20.000369
ORF1ab/nsp4397Y397YtaCtaT44B.1.1.10.001307
ORF1ab/nsp4397Y397YtaCtaT44B.1.2580.000266
ORF1ab/nsp4397Y397YtaCtaT44B.1.6210.000354
ORF1ab/nsp4397Y397YtaCtaT44C.370.000464
ORF1ab/nsp4397Y397YtaCtaT33AY.530.000863
ORF1ab/nsp4397Y397YtaCtaT33AY.70.000588
ORF1ab/nsp4397Y397YtaCtaT33AY.90.000203
ORF1ab/nsp4397Y397YtaCtaT33B.1.5610.001191
ORF1ab/nsp4397Y397YtaCtaT33P.1.140.000143
ORF1ab/nsp4397Y397YtaCtaT33Q.40.001364
ORF1ab/nsp4397Y397YtaCtaT22A.190.018868
ORF1ab/nsp4397Y397YtaCtaT22AY.1020.000053
ORF1ab/nsp4397Y397YtaCtaT22AY.1190.000071
ORF1ab/nsp4397Y397YtaCtaT22AY.330.000134
ORF1ab/nsp4397Y397YtaCtaT22AY.39.10.000079
ORF1ab/nsp4397Y397YtaCtaT22AY.4.20.000043
ORF1ab/nsp4397Y397YtaCtaT22AY.46.20.001271
ORF1ab/nsp4397Y397YtaCtaT22B.1.1.1900.1
ORF1ab/nsp4397Y397YtaCtaT22B.1.1.2220.000408
ORF1ab/nsp4397Y397YtaCtaT22B.1.1.3060.000877
ORF1ab/nsp4397Y397YtaCtaT22B.1.177.110.003396
ORF1ab/nsp4397Y397YtaCtaT22B.1.2390.002442
ORF1ab/nsp4397Y397YtaCtaT22B.1.36.260.005714
ORF1ab/nsp4397Y397YtaCtaT22B.1.4250.005988
ORF1ab/nsp4397Y397YtaCtaT22B.1.4260.002018
ORF1ab/nsp4397Y397YtaCtaT22B.1.5950.000522
ORF1ab/nsp4397Y397YtaCtaT22B.1.6230.001073
ORF1ab/nsp4397Y397YtaCtaT11A0.000387
ORF1ab/nsp4397Y397YtaCtaT11AY.1160.000287
ORF1ab/nsp4397Y397YtaCtaT11AY.1170.000085
ORF1ab/nsp4397Y397YtaCtaT11AY.160.00038
ORF1ab/nsp4397Y397YtaCtaT11AY.200.000039
ORF1ab/nsp4397Y397YtaCtaT11AY.230.00007
ORF1ab/nsp4397Y397YtaCtaT11AY.290.000016
ORF1ab/nsp4397Y397YtaCtaT11AY.420.00004
ORF1ab/nsp4397Y397YtaCtaT11AY.46.60.000072
ORF1ab/nsp4397Y397YtaCtaT11AY.620.000436
ORF1ab/nsp4397Y397YtaCtaT11AY.680.000274
ORF1ab/nsp4397Y397YtaCtaT11AY.710.000475
ORF1ab/nsp4397Y397YtaCtaT11AY.750.000056
ORF1ab/nsp4397Y397YtaCtaT11AY.75.10.00018
ORF1ab/nsp4397Y397YtaCtaT11AY.9.10.000084
ORF1ab/nsp4397Y397YtaCtaT11AY.9.20.000037
ORF1ab/nsp4397Y397YtaCtaT11AY.980.000079
ORF1ab/nsp4397Y397YtaCtaT11B0.000128
ORF1ab/nsp4397Y397YtaCtaT11B.1.1.1410.002012
ORF1ab/nsp4397Y397YtaCtaT11B.1.1.2140.000055
ORF1ab/nsp4397Y397YtaCtaT11B.1.1.3110.000358
ORF1ab/nsp4397Y397YtaCtaT11B.1.1.370.000193
ORF1ab/nsp4397Y397YtaCtaT11B.1.1.3720.000689
ORF1ab/nsp4397Y397YtaCtaT11B.1.1.410.006329
ORF1ab/nsp4397Y397YtaCtaT11B.1.1.4340.000349
ORF1ab/nsp4397Y397YtaCtaT11B.1.1.4640.001473
ORF1ab/nsp4397Y397YtaCtaT11B.1.1.4870.005587
ORF1ab/nsp4397Y397YtaCtaT11B.1.130.002375
ORF1ab/nsp4397Y397YtaCtaT11B.1.1600.000031
ORF1ab/nsp4397Y397YtaCtaT11B.1.177.160.000664
ORF1ab/nsp4397Y397YtaCtaT11B.1.177.40.000211
ORF1ab/nsp4397Y397YtaCtaT11B.1.177.820.000477
ORF1ab/nsp4397Y397YtaCtaT11B.1.177.860.000183
ORF1ab/nsp4397Y397YtaCtaT11B.1.2340.000132
ORF1ab/nsp4397Y397YtaCtaT11B.1.2400.000216
ORF1ab/nsp4397Y397YtaCtaT11B.1.3240.001605
ORF1ab/nsp4397Y397YtaCtaT11B.1.351.30.000876
ORF1ab/nsp4397Y397YtaCtaT11B.1.36.170.000494
ORF1ab/nsp4397Y397YtaCtaT11B.1.466.20.000391
ORF1ab/nsp4397Y397YtaCtaT11B.1.4700.001404
ORF1ab/nsp4397Y397YtaCtaT11B.1.5260.000024
ORF1ab/nsp4397Y397YtaCtaT11B.1.5400.009709
ORF1ab/nsp4397Y397YtaCtaT11B.1.575.10.002439
ORF1ab/nsp4397Y397YtaCtaT11B.1.5970.00463
ORF1ab/nsp4397Y397YtaCtaT11B.450.003831
ORF1ab/nsp4397Y397YtaCtaT11P.1.150.000232
ORF1ab/nsp4397Y397YtaCtaT11P.1.17.10.000875
ORF1ab/nsp4397Y397YtaCtaT11P.1.70.000319
ORF1ab/nsp4397Y397YtaCtaT11Q.80.000165
ORF1ab/nsp4397Y397YtaCtaT11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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