CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = Y142Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4142Y142YY2905YsyntaCtaT2317231718978-8980

Details of the mutation Y142Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4142Y142YtaCtaT23172317All0.000443
ORF1ab/nsp4142Y142YtaCtaT330330B.1.1.70.000295
ORF1ab/nsp4142Y142YtaCtaT306306P.60.962264
ORF1ab/nsp4142Y142YtaCtaT258258AY.90.01744
ORF1ab/nsp4142Y142YtaCtaT166166B.1.617.20.000625
ORF1ab/nsp4142Y142YtaCtaT144144AY.230.010044
ORF1ab/nsp4142Y142YtaCtaT104104AY.1020.002757
ORF1ab/nsp4142Y142YtaCtaT8383AY.40.000129
ORF1ab/nsp4142Y142YtaCtaT7676AY.440.000463
ORF1ab/nsp4142Y142YtaCtaT6161B.1.20.000537
ORF1ab/nsp4142Y142YtaCtaT5252B.1.4090.040625
ORF1ab/nsp4142Y142YtaCtaT4242AY.1030.000261
ORF1ab/nsp4142Y142YtaCtaT3939AY.250.000235
ORF1ab/nsp4142Y142YtaCtaT3232B.1.177.210.002447
ORF1ab/nsp4142Y142YtaCtaT3232B.1.2210.002273
ORF1ab/nsp4142Y142YtaCtaT3131P.10.000488
ORF1ab/nsp4142Y142YtaCtaT3030AY.430.000133
ORF1ab/nsp4142Y142YtaCtaT2424A.20.015884
ORF1ab/nsp4142Y142YtaCtaT2424AY.500.019185
ORF1ab/nsp4142Y142YtaCtaT2323AY.980.001817
ORF1ab/nsp4142Y142YtaCtaT2323P.20.004293
ORF1ab/nsp4142Y142YtaCtaT2121B.1.3690.00599
ORF1ab/nsp4142Y142YtaCtaT2020AY.30.000199
ORF1ab/nsp4142Y142YtaCtaT2020B.10.000183
ORF1ab/nsp4142Y142YtaCtaT1919AY.290.0003
ORF1ab/nsp4142Y142YtaCtaT1919AY.9.20.000698
ORF1ab/nsp4142Y142YtaCtaT1919B.1.258.170.001975
ORF1ab/nsp4142Y142YtaCtaT1717AY.390.00042
ORF1ab/nsp4142Y142YtaCtaT1414B.1.2390.017094
ORF1ab/nsp4142Y142YtaCtaT1212B.1.1770.000158
ORF1ab/nsp4142Y142YtaCtaT1111B.1.1.5190.000437
ORF1ab/nsp4142Y142YtaCtaT1010AY.50.000206
ORF1ab/nsp4142Y142YtaCtaT99B.1.5260.000212
ORF1ab/nsp4142Y142YtaCtaT88B.1.2580.000532
ORF1ab/nsp4142Y142YtaCtaT88B.1.3510.000238
ORF1ab/nsp4142Y142YtaCtaT88B.1.4270.000404
ORF1ab/nsp4142Y142YtaCtaT77AY.1200.00026
ORF1ab/nsp4142Y142YtaCtaT77Q.30.001015
ORF1ab/nsp4142Y142YtaCtaT66AY.460.000624
ORF1ab/nsp4142Y142YtaCtaT66B.1.10.000109
ORF1ab/nsp4142Y142YtaCtaT66B.1.6210.000531
ORF1ab/nsp4142Y142YtaCtaT55AY.46.20.003177
ORF1ab/nsp4142Y142YtaCtaT55B0.000639
ORF1ab/nsp4142Y142YtaCtaT55B.1.5820.002453
ORF1ab/nsp4142Y142YtaCtaT55C.370.00058
ORF1ab/nsp4142Y142YtaCtaT44AY.130.000644
ORF1ab/nsp4142Y142YtaCtaT44AY.260.000113
ORF1ab/nsp4142Y142YtaCtaT44AY.300.001583
ORF1ab/nsp4142Y142YtaCtaT44AY.60.000165
ORF1ab/nsp4142Y142YtaCtaT44AY.610.000419
ORF1ab/nsp4142Y142YtaCtaT44B.1.1.1760.001757
ORF1ab/nsp4142Y142YtaCtaT44B.1.177.810.000757
ORF1ab/nsp4142Y142YtaCtaT44P.1.170.000647
ORF1ab/nsp4142Y142YtaCtaT33A.270.004967
ORF1ab/nsp4142Y142YtaCtaT33AY.1160.00086
ORF1ab/nsp4142Y142YtaCtaT33AY.1180.000188
ORF1ab/nsp4142Y142YtaCtaT33AY.200.000117
ORF1ab/nsp4142Y142YtaCtaT33AY.29.10.000662
ORF1ab/nsp4142Y142YtaCtaT33AY.4.10.002212
ORF1ab/nsp4142Y142YtaCtaT33AY.450.000365
ORF1ab/nsp4142Y142YtaCtaT33AY.470.000093
ORF1ab/nsp4142Y142YtaCtaT33AY.5.30.001012
ORF1ab/nsp4142Y142YtaCtaT33AY.750.000168
ORF1ab/nsp4142Y142YtaCtaT33B.1.1.280.000934
ORF1ab/nsp4142Y142YtaCtaT33B.1.1600.000094
ORF1ab/nsp4142Y142YtaCtaT33B.1.177.860.00055
ORF1ab/nsp4142Y142YtaCtaT33B.1.2340.000396
ORF1ab/nsp4142Y142YtaCtaT33B.1.2400.000647
ORF1ab/nsp4142Y142YtaCtaT33B.1.2430.000209
ORF1ab/nsp4142Y142YtaCtaT33B.1.4990.003151
ORF1ab/nsp4142Y142YtaCtaT33P.1.120.001452
ORF1ab/nsp4142Y142YtaCtaT22A.23.10.001408
ORF1ab/nsp4142Y142YtaCtaT22AY.330.000134
ORF1ab/nsp4142Y142YtaCtaT22AY.690.000373
ORF1ab/nsp4142Y142YtaCtaT22AY.940.000885
ORF1ab/nsp4142Y142YtaCtaT22B.1.1.2140.000111
ORF1ab/nsp4142Y142YtaCtaT22B.1.1.3180.000604
ORF1ab/nsp4142Y142YtaCtaT22B.1.177.150.001262
ORF1ab/nsp4142Y142YtaCtaT22B.1.36.290.001035
ORF1ab/nsp4142Y142YtaCtaT22B.1.4970.00063
ORF1ab/nsp4142Y142YtaCtaT22B.1.6370.000146
ORF1ab/nsp4142Y142YtaCtaT22D.20.00015
ORF1ab/nsp4142Y142YtaCtaT22P.1.140.000096
ORF1ab/nsp4142Y142YtaCtaT11A0.000387
ORF1ab/nsp4142Y142YtaCtaT11A.50.001923
ORF1ab/nsp4142Y142YtaCtaT11AE.80.000489
ORF1ab/nsp4142Y142YtaCtaT11AY.100.00053
ORF1ab/nsp4142Y142YtaCtaT11AY.1170.000085
ORF1ab/nsp4142Y142YtaCtaT11AY.1190.000035
ORF1ab/nsp4142Y142YtaCtaT11AY.120.10.000321
ORF1ab/nsp4142Y142YtaCtaT11AY.16.10.00047
ORF1ab/nsp4142Y142YtaCtaT11AY.210.001898
ORF1ab/nsp4142Y142YtaCtaT11AY.3.10.000085
ORF1ab/nsp4142Y142YtaCtaT11AY.320.000532
ORF1ab/nsp4142Y142YtaCtaT11AY.340.000097
ORF1ab/nsp4142Y142YtaCtaT11AY.4.20.000022
ORF1ab/nsp4142Y142YtaCtaT11AY.4.2.10.000149
ORF1ab/nsp4142Y142YtaCtaT11AY.420.00004
ORF1ab/nsp4142Y142YtaCtaT11AY.46.40.000165
ORF1ab/nsp4142Y142YtaCtaT11AY.46.60.000072
ORF1ab/nsp4142Y142YtaCtaT11AY.480.000465
ORF1ab/nsp4142Y142YtaCtaT11AY.490.003195
ORF1ab/nsp4142Y142YtaCtaT11AY.5.40.000277
ORF1ab/nsp4142Y142YtaCtaT11AY.7.10.000113
ORF1ab/nsp4142Y142YtaCtaT11AY.740.000116
ORF1ab/nsp4142Y142YtaCtaT11AY.75.10.00018
ORF1ab/nsp4142Y142YtaCtaT11AY.840.000437
ORF1ab/nsp4142Y142YtaCtaT11AY.9.10.000084
ORF1ab/nsp4142Y142YtaCtaT11AY.99.20.000092
ORF1ab/nsp4142Y142YtaCtaT11AZ.10.000867
ORF1ab/nsp4142Y142YtaCtaT11B.1.1.10.000327
ORF1ab/nsp4142Y142YtaCtaT11B.1.1.120.007463
ORF1ab/nsp4142Y142YtaCtaT11B.1.1.2240.014286
ORF1ab/nsp4142Y142YtaCtaT11B.1.1.3500.04
ORF1ab/nsp4142Y142YtaCtaT11B.1.1.390.00051
ORF1ab/nsp4142Y142YtaCtaT11B.1.1.630.000386
ORF1ab/nsp4142Y142YtaCtaT11B.1.177.100.000878
ORF1ab/nsp4142Y142YtaCtaT11B.1.177.120.000152
ORF1ab/nsp4142Y142YtaCtaT11B.1.177.560.000668
ORF1ab/nsp4142Y142YtaCtaT11B.1.177.600.000218
ORF1ab/nsp4142Y142YtaCtaT11B.1.177.70.000165
ORF1ab/nsp4142Y142YtaCtaT11B.1.2930.0125
ORF1ab/nsp4142Y142YtaCtaT11B.1.3110.000275
ORF1ab/nsp4142Y142YtaCtaT11B.1.3400.004292
ORF1ab/nsp4142Y142YtaCtaT11B.1.3460.001311
ORF1ab/nsp4142Y142YtaCtaT11B.1.360.000146
ORF1ab/nsp4142Y142YtaCtaT11B.1.36.100.004785
ORF1ab/nsp4142Y142YtaCtaT11B.1.3670.000792
ORF1ab/nsp4142Y142YtaCtaT11B.1.3970.004854
ORF1ab/nsp4142Y142YtaCtaT11B.1.4220.000812
ORF1ab/nsp4142Y142YtaCtaT11B.1.438.10.000107
ORF1ab/nsp4142Y142YtaCtaT11B.1.4620.007246
ORF1ab/nsp4142Y142YtaCtaT11B.1.4710.002732
ORF1ab/nsp4142Y142YtaCtaT11B.1.4800.002488
ORF1ab/nsp4142Y142YtaCtaT11B.1.5010.007353
ORF1ab/nsp4142Y142YtaCtaT11B.1.5610.000397
ORF1ab/nsp4142Y142YtaCtaT11B.1.5880.00091
ORF1ab/nsp4142Y142YtaCtaT11B.1.5960.000087
ORF1ab/nsp4142Y142YtaCtaT11B.1.6090.000479
ORF1ab/nsp4142Y142YtaCtaT11B.1.617.10.000129
ORF1ab/nsp4142Y142YtaCtaT11B.1.6280.000352
ORF1ab/nsp4142Y142YtaCtaT11B.1.6300.005236
ORF1ab/nsp4142Y142YtaCtaT11B.1.930.000934

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.