CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = V498V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4498V498VV3261VsyngtTgtC8577950.92765510046-10048
ORF1ab/nsp4498V498VV3261VsyngtTgtG857530.061843610046-10048
ORF1ab/nsp4498V498VV3261VsyngtTgtA85790.010501810046-10048

Details of the mutation V498V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4498V498VgtTgtC795857All0.000152
ORF1ab/nsp4498V498VgtTgtG53857All0.00001
ORF1ab/nsp4498V498VgtTgtA9857All0.000002
ORF1ab/nsp4498V498VgtTgtC261261B.1.1.5190.010365
ORF1ab/nsp4498V498VgtTgtC127127B.1.5770.087285
ORF1ab/nsp4498V498VgtTgtC81103B.1.1.70.000073
ORF1ab/nsp4498V498VgtTgtG19103B.1.1.70.000017
ORF1ab/nsp4498V498VgtTgtA3103B.1.1.70.000003
ORF1ab/nsp4498V498VgtTgtC8383Q.60.549669
ORF1ab/nsp4498V498VgtTgtC5050AY.60.002056
ORF1ab/nsp4498V498VgtTgtC3842AY.40.000059
ORF1ab/nsp4498V498VgtTgtG442AY.40.000006
ORF1ab/nsp4498V498VgtTgtC2425B.1.20.000211
ORF1ab/nsp4498V498VgtTgtG125B.1.20.000009
ORF1ab/nsp4498V498VgtTgtC1616B.1.1770.000211
ORF1ab/nsp4498V498VgtTgtG1313AY.1200.000483
ORF1ab/nsp4498V498VgtTgtC1313B.1.2430.000905
ORF1ab/nsp4498V498VgtTgtC79B.10.000064
ORF1ab/nsp4498V498VgtTgtA19B.10.000009
ORF1ab/nsp4498V498VgtTgtG19B.10.000009
ORF1ab/nsp4498V498VgtTgtC78AY.430.000031
ORF1ab/nsp4498V498VgtTgtG18AY.430.000004
ORF1ab/nsp4498V498VgtTgtC68B.1.10.000109
ORF1ab/nsp4498V498VgtTgtG28B.1.10.000036
ORF1ab/nsp4498V498VgtTgtC88B.1.1.3170.003294
ORF1ab/nsp4498V498VgtTgtC66AY.30.00006
ORF1ab/nsp4498V498VgtTgtG36B.1.4290.000071
ORF1ab/nsp4498V498VgtTgtC36B.1.4290.000071
ORF1ab/nsp4498V498VgtTgtC45B.1.1600.000125
ORF1ab/nsp4498V498VgtTgtG15B.1.1600.000031
ORF1ab/nsp4498V498VgtTgtC55B.1.5950.001305
ORF1ab/nsp4498V498VgtTgtC55B.1.617.20.000019
ORF1ab/nsp4498V498VgtTgtC34P.10.000047
ORF1ab/nsp4498V498VgtTgtG14P.10.000016
ORF1ab/nsp4498V498VgtTgtC23AY.330.000134
ORF1ab/nsp4498V498VgtTgtG13AY.330.000067
ORF1ab/nsp4498V498VgtTgtC23B.1.4270.000101
ORF1ab/nsp4498V498VgtTgtA13B.1.4270.00005
ORF1ab/nsp4498V498VgtTgtC33B.1.5260.000071
ORF1ab/nsp4498V498VgtTgtC33B.1.6370.000219
ORF1ab/nsp4498V498VgtTgtC22AY.1020.000053
ORF1ab/nsp4498V498VgtTgtC22AY.1030.000012
ORF1ab/nsp4498V498VgtTgtG12AY.250.000006
ORF1ab/nsp4498V498VgtTgtC12AY.250.000006
ORF1ab/nsp4498V498VgtTgtG22AY.630.000774
ORF1ab/nsp4498V498VgtTgtC22B.1.177.40.000422
ORF1ab/nsp4498V498VgtTgtC22B.1.177.860.000367
ORF1ab/nsp4498V498VgtTgtC22B.1.351.30.001753
ORF1ab/nsp4498V498VgtTgtC22B.1.595.30.052632
ORF1ab/nsp4498V498VgtTgtC11AY.1000.000046
ORF1ab/nsp4498V498VgtTgtC11AY.160.00038
ORF1ab/nsp4498V498VgtTgtA11AY.260.000028
ORF1ab/nsp4498V498VgtTgtC11AY.390.000025
ORF1ab/nsp4498V498VgtTgtA11AY.4.20.000022
ORF1ab/nsp4498V498VgtTgtC11AY.420.00004
ORF1ab/nsp4498V498VgtTgtC11AY.46.40.000165
ORF1ab/nsp4498V498VgtTgtC11AY.50.000021
ORF1ab/nsp4498V498VgtTgtC11AY.610.000105
ORF1ab/nsp4498V498VgtTgtC11AY.850.000427
ORF1ab/nsp4498V498VgtTgtC11AY.99.20.000092
ORF1ab/nsp4498V498VgtTgtA11B.1.1.2770.000759
ORF1ab/nsp4498V498VgtTgtC11B.1.1.2840.000107
ORF1ab/nsp4498V498VgtTgtA11B.1.1.3510.002793
ORF1ab/nsp4498V498VgtTgtC11B.1.1.4110.014706
ORF1ab/nsp4498V498VgtTgtC11B.1.177.230.003236
ORF1ab/nsp4498V498VgtTgtG11B.1.177.430.001477
ORF1ab/nsp4498V498VgtTgtC11B.1.177.770.000726
ORF1ab/nsp4498V498VgtTgtC11B.1.221.40.004167
ORF1ab/nsp4498V498VgtTgtC11B.1.2340.000132
ORF1ab/nsp4498V498VgtTgtC11B.1.3620.001541
ORF1ab/nsp4498V498VgtTgtC11B.1.400.10.015152
ORF1ab/nsp4498V498VgtTgtG11B.1.4970.000315
ORF1ab/nsp4498V498VgtTgtC11B.1.499.10.111111
ORF1ab/nsp4498V498VgtTgtC11B.1.5960.000087
ORF1ab/nsp4498V498VgtTgtC11B.1.617.10.000129
ORF1ab/nsp4498V498VgtTgtG11B.1.6270.00202
ORF1ab/nsp4498V498VgtTgtC11B.100.008264
ORF1ab/nsp4498V498VgtTgtC11C.1.20.004255
ORF1ab/nsp4498V498VgtTgtC11C.300.001727
ORF1ab/nsp4498V498VgtTgtC11C.37.10.002618
ORF1ab/nsp4498V498VgtTgtC11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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