CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = V314V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4314V314VV3077VsyngtAgtG6235970.9582669494-9496
ORF1ab/nsp4314V314VV3077VsyngtAgtT623200.03210279494-9496
ORF1ab/nsp4314V314VV3077VsyngtAgtC62360.009630829494-9496

Details of the mutation V314V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4314V314VgtAgtG597623All0.000114
ORF1ab/nsp4314V314VgtAgtT20623All0.000004
ORF1ab/nsp4314V314VgtAgtC6623All0.000001
ORF1ab/nsp4314V314VgtAgtG382382AY.390.00944
ORF1ab/nsp4314V314VgtAgtG3838B.1.6210.003364
ORF1ab/nsp4314V314VgtAgtG2122B.1.617.20.000079
ORF1ab/nsp4314V314VgtAgtT122B.1.617.20.000004
ORF1ab/nsp4314V314VgtAgtG2020B.1.258.170.002079
ORF1ab/nsp4314V314VgtAgtG1119B.1.1.70.00001
ORF1ab/nsp4314V314VgtAgtT619B.1.1.70.000005
ORF1ab/nsp4314V314VgtAgtC219B.1.1.70.000002
ORF1ab/nsp4314V314VgtAgtG1316AY.40.00002
ORF1ab/nsp4314V314VgtAgtT316AY.40.000005
ORF1ab/nsp4314V314VgtAgtG1515B.1.177.291
ORF1ab/nsp4314V314VgtAgtG1010AY.440.000061
ORF1ab/nsp4314V314VgtAgtG99AY.1020.000239
ORF1ab/nsp4314V314VgtAgtG77AY.250.000042
ORF1ab/nsp4314V314VgtAgtG66AY.340.000582
ORF1ab/nsp4314V314VgtAgtG44AY.30.00004
ORF1ab/nsp4314V314VgtAgtG44AY.430.000018
ORF1ab/nsp4314V314VgtAgtG34B0.000383
ORF1ab/nsp4314V314VgtAgtT14B0.000128
ORF1ab/nsp4314V314VgtAgtG33AY.1000.000138
ORF1ab/nsp4314V314VgtAgtG33AY.1030.000019
ORF1ab/nsp4314V314VgtAgtG33AY.230.000209
ORF1ab/nsp4314V314VgtAgtG23B.1.1770.000026
ORF1ab/nsp4314V314VgtAgtC13B.1.1770.000013
ORF1ab/nsp4314V314VgtAgtT220.111111
ORF1ab/nsp4314V314VgtAgtG22AY.1170.000169
ORF1ab/nsp4314V314VgtAgtG22AY.1210.000271
ORF1ab/nsp4314V314VgtAgtC12AY.260.000028
ORF1ab/nsp4314V314VgtAgtG12AY.260.000028
ORF1ab/nsp4314V314VgtAgtG22AY.3.10.000171
ORF1ab/nsp4314V314VgtAgtG22AY.450.000243
ORF1ab/nsp4314V314VgtAgtG22AY.470.000062
ORF1ab/nsp4314V314VgtAgtG12AY.50.000021
ORF1ab/nsp4314V314VgtAgtT12AY.50.000021
ORF1ab/nsp4314V314VgtAgtG22AY.590.001059
ORF1ab/nsp4314V314VgtAgtG22AY.60.000082
ORF1ab/nsp4314V314VgtAgtG22B.1.20.000018
ORF1ab/nsp4314V314VgtAgtG22B.1.2210.000142
ORF1ab/nsp4314V314VgtAgtG12B.1.3510.00003
ORF1ab/nsp4314V314VgtAgtT12B.1.3510.00003
ORF1ab/nsp4314V314VgtAgtG22B.1.4290.000047
ORF1ab/nsp4314V314VgtAgtG22B.1.6370.000146
ORF1ab/nsp4314V314VgtAgtG11AE.80.000489
ORF1ab/nsp4314V314VgtAgtG11AY.1180.000063
ORF1ab/nsp4314V314VgtAgtG11AY.290.000016
ORF1ab/nsp4314V314VgtAgtG11AY.34.10.00051
ORF1ab/nsp4314V314VgtAgtG11AY.39.10.00004
ORF1ab/nsp4314V314VgtAgtC11AY.4.2.10.000149
ORF1ab/nsp4314V314VgtAgtG11AY.420.00004
ORF1ab/nsp4314V314VgtAgtC11AY.46.50.000198
ORF1ab/nsp4314V314VgtAgtG11AY.5.30.000337
ORF1ab/nsp4314V314VgtAgtG11AY.740.000116
ORF1ab/nsp4314V314VgtAgtG11AY.750.000056
ORF1ab/nsp4314V314VgtAgtG11AZ.10.000867
ORF1ab/nsp4314V314VgtAgtT11B.1.10.000018
ORF1ab/nsp4314V314VgtAgtG11B.1.1.2790.001121
ORF1ab/nsp4314V314VgtAgtG11B.1.1.2840.000107
ORF1ab/nsp4314V314VgtAgtG11B.1.1.3060.000438
ORF1ab/nsp4314V314VgtAgtT11B.1.1.3160.000925
ORF1ab/nsp4314V314VgtAgtT11B.1.1.3180.000302
ORF1ab/nsp4314V314VgtAgtT11B.1.1.3690.000446
ORF1ab/nsp4314V314VgtAgtT11B.1.36.390.002217
ORF1ab/nsp4314V314VgtAgtG11B.1.4270.00005
ORF1ab/nsp4314V314VgtAgtG11B.1.5260.000024
ORF1ab/nsp4314V314VgtAgtG11B.1.5680.001111
ORF1ab/nsp4314V314VgtAgtG11P.10.000016
ORF1ab/nsp4314V314VgtAgtG11P.1.140.000048

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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