CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = T419T

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4419T419TT3182TsynacCacT374236210.9676649809-9811
ORF1ab/nsp4419T419TT3182TsynacCacA37421190.03180129809-9811
ORF1ab/nsp4419T419TT3182TsynacCacG374220.0005344749809-9811

Details of the mutation T419T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4419T419TacCacT36213742All0.000693
ORF1ab/nsp4419T419TacCacA1193742All0.000023
ORF1ab/nsp4419T419TacCacG23742All0
ORF1ab/nsp4419T419TacCacT17641764AY.1060.590757
ORF1ab/nsp4419T419TacCacT443446AY.40.000689
ORF1ab/nsp4419T419TacCacA2446AY.40.000003
ORF1ab/nsp4419T419TacCacG1446AY.40.000002
ORF1ab/nsp4419T419TacCacT388390AY.250.002334
ORF1ab/nsp4419T419TacCacA2390AY.250.000012
ORF1ab/nsp4419T419TacCacT264286B.1.1.70.000236
ORF1ab/nsp4419T419TacCacA22286B.1.1.70.00002
ORF1ab/nsp4419T419TacCacT8686B.1.20.000757
ORF1ab/nsp4419T419TacCacT6570AY.440.000396
ORF1ab/nsp4419T419TacCacA570AY.440.00003
ORF1ab/nsp4419T419TacCacT5959B.1.258.220.157333
ORF1ab/nsp4419T419TacCacT4449B.1.617.20.000166
ORF1ab/nsp4419T419TacCacA549B.1.617.20.000019
ORF1ab/nsp4419T419TacCacT2737B.10.000247
ORF1ab/nsp4419T419TacCacA1037B.10.000092
ORF1ab/nsp4419T419TacCacT2931AY.430.000128
ORF1ab/nsp4419T419TacCacA231AY.430.000009
ORF1ab/nsp4419T419TacCacT3131P.1.140.001482
ORF1ab/nsp4419T419TacCacT2525P.10.000394
ORF1ab/nsp4419T419TacCacT1120AY.1030.000068
ORF1ab/nsp4419T419TacCacA920AY.1030.000056
ORF1ab/nsp4419T419TacCacT1820AY.30.000179
ORF1ab/nsp4419T419TacCacA220AY.30.00002
ORF1ab/nsp4419T419TacCacT1617B.1.10.00029
ORF1ab/nsp4419T419TacCacA117B.1.10.000018
ORF1ab/nsp4419T419TacCacT1717B.1.4740.032319
ORF1ab/nsp4419T419TacCacT1616B.1.4290.000376
ORF1ab/nsp4419T419TacCacT1314B.1.1770.000171
ORF1ab/nsp4419T419TacCacA114B.1.1770.000013
ORF1ab/nsp4419T419TacCacT1414B.1.177.730.007928
ORF1ab/nsp4419T419TacCacT1414B.1.2210.000994
ORF1ab/nsp4419T419TacCacA812AY.1020.000212
ORF1ab/nsp4419T419TacCacT412AY.1020.000106
ORF1ab/nsp4419T419TacCacA1111AY.90.000744
ORF1ab/nsp4419T419TacCacT1111B.1.3110.00302
ORF1ab/nsp4419T419TacCacA79AY.230.000488
ORF1ab/nsp4419T419TacCacT29AY.230.000139
ORF1ab/nsp4419T419TacCacT99AY.750.000504
ORF1ab/nsp4419T419TacCacT88AY.9.20.000294
ORF1ab/nsp4419T419TacCacT88AY.990.008395
ORF1ab/nsp4419T419TacCacT88B.1.1.4340.002788
ORF1ab/nsp4419T419TacCacT77AJ.10.318182
ORF1ab/nsp4419T419TacCacT47AY.1190.000141
ORF1ab/nsp4419T419TacCacA37AY.1190.000106
ORF1ab/nsp4419T419TacCacT77AY.3.10.000597
ORF1ab/nsp4419T419TacCacT77AY.46.60.000505
ORF1ab/nsp4419T419TacCacT77B.1.5260.000165
ORF1ab/nsp4419T419TacCacT57B.1.617.10.000645
ORF1ab/nsp4419T419TacCacA27B.1.617.10.000258
ORF1ab/nsp4419T419TacCacT66AY.200.000233
ORF1ab/nsp4419T419TacCacT66AY.260.00017
ORF1ab/nsp4419T419TacCacT56AY.4.50.000537
ORF1ab/nsp4419T419TacCacA16AY.4.50.000107
ORF1ab/nsp4419T419TacCacT66B.1.1.5190.000238
ORF1ab/nsp4419T419TacCacT66B.1.2430.000418
ORF1ab/nsp4419T419TacCacT55AY.1130.000712
ORF1ab/nsp4419T419TacCacA55AY.390.000124
ORF1ab/nsp4419T419TacCacT55AY.50.000103
ORF1ab/nsp4419T419TacCacT45B0.000511
ORF1ab/nsp4419T419TacCacA15B0.000128
ORF1ab/nsp4419T419TacCacT55B.1.360.00073
ORF1ab/nsp4419T419TacCacT44AY.420.000161
ORF1ab/nsp4419T419TacCacT44AY.46.30.003735
ORF1ab/nsp4419T419TacCacT44B.1.1.2140.000222
ORF1ab/nsp4419T419TacCacT44B.1.6210.000354
ORF1ab/nsp4419T419TacCacT44R.10.00036
ORF1ab/nsp4419T419TacCacT23AY.290.000032
ORF1ab/nsp4419T419TacCacA13AY.290.000016
ORF1ab/nsp4419T419TacCacT23AY.550.001835
ORF1ab/nsp4419T419TacCacA13AY.550.000917
ORF1ab/nsp4419T419TacCacT23AY.98.10.000097
ORF1ab/nsp4419T419TacCacA13AY.98.10.000048
ORF1ab/nsp4419T419TacCacT23B.1.1.10.000653
ORF1ab/nsp4419T419TacCacA13B.1.1.10.000327
ORF1ab/nsp4419T419TacCacT33B.1.1.280.000934
ORF1ab/nsp4419T419TacCacT33B.1.1.330.001263
ORF1ab/nsp4419T419TacCacT33B.1.1.370.000579
ORF1ab/nsp4419T419TacCacT33B.1.2340.000396
ORF1ab/nsp4419T419TacCacT33B.1.2580.0002
ORF1ab/nsp4419T419TacCacT33B.1.3510.000089
ORF1ab/nsp4419T419TacCacT33B.1.4090.002344
ORF1ab/nsp4419T419TacCacA33B.1.4260.003027
ORF1ab/nsp4419T419TacCacT33B.1.4270.000151
ORF1ab/nsp4419T419TacCacT33B.1.5230.007353
ORF1ab/nsp4419T419TacCacT33C.370.000348
ORF1ab/nsp4419T419TacCacT33D.20.000225
ORF1ab/nsp4419T419TacCacG120.055556
ORF1ab/nsp4419T419TacCacT120.055556
ORF1ab/nsp4419T419TacCacT22AY.1010.000981
ORF1ab/nsp4419T419TacCacT12AY.300.000396
ORF1ab/nsp4419T419TacCacA12AY.300.000396
ORF1ab/nsp4419T419TacCacT22AY.360.000296
ORF1ab/nsp4419T419TacCacT12AY.39.10.00004
ORF1ab/nsp4419T419TacCacA12AY.39.10.00004
ORF1ab/nsp4419T419TacCacT22AY.4.20.000043
ORF1ab/nsp4419T419TacCacT22AY.470.000062
ORF1ab/nsp4419T419TacCacA12AY.520.000814
ORF1ab/nsp4419T419TacCacT12AY.520.000814
ORF1ab/nsp4419T419TacCacT22AY.590.001059
ORF1ab/nsp4419T419TacCacT22AY.620.000871
ORF1ab/nsp4419T419TacCacT22AY.700.000417
ORF1ab/nsp4419T419TacCacA22B.1.1.1210.004854
ORF1ab/nsp4419T419TacCacT22B.1.1.2840.000215
ORF1ab/nsp4419T419TacCacT22B.1.1.2890.004167
ORF1ab/nsp4419T419TacCacT22B.1.1.3180.000604
ORF1ab/nsp4419T419TacCacT22B.1.1.4090.005666
ORF1ab/nsp4419T419TacCacT22B.1.1580.047619
ORF1ab/nsp4419T419TacCacT22B.1.177.570.000562
ORF1ab/nsp4419T419TacCacT22B.1.177.820.000955
ORF1ab/nsp4419T419TacCacT22B.1.3710.002245
ORF1ab/nsp4419T419TacCacT22B.1.4000.000858
ORF1ab/nsp4419T419TacCacT22B.1.4920.014085
ORF1ab/nsp4419T419TacCacT22B.1.5960.000174
ORF1ab/nsp4419T419TacCacT22B.1.6280.000705
ORF1ab/nsp4419T419TacCacT11A.10.000282
ORF1ab/nsp4419T419TacCacT11AY.1050.000643
ORF1ab/nsp4419T419TacCacT11AY.1170.000085
ORF1ab/nsp4419T419TacCacT11AY.23.10.000417
ORF1ab/nsp4419T419TacCacA11AY.34.10.00051
ORF1ab/nsp4419T419TacCacT11AY.400.000964
ORF1ab/nsp4419T419TacCacT11AY.410.000294
ORF1ab/nsp4419T419TacCacT11AY.460.000104
ORF1ab/nsp4419T419TacCacT11AY.580.000907
ORF1ab/nsp4419T419TacCacT11AY.60.000041
ORF1ab/nsp4419T419TacCacT11AY.7.10.000113
ORF1ab/nsp4419T419TacCacT11AY.75.10.00018
ORF1ab/nsp4419T419TacCacT11AY.840.000437
ORF1ab/nsp4419T419TacCacT11AY.920.000287
ORF1ab/nsp4419T419TacCacT11AY.99.20.000092
ORF1ab/nsp4419T419TacCacA11B.1.1.120.007463
ORF1ab/nsp4419T419TacCacT11B.1.1.1270.0625
ORF1ab/nsp4419T419TacCacT11B.1.1.1610.003534
ORF1ab/nsp4419T419TacCacT11B.1.1.1890.001513
ORF1ab/nsp4419T419TacCacT11B.1.1.2160.00089
ORF1ab/nsp4419T419TacCacT11B.1.1.2820.011628
ORF1ab/nsp4419T419TacCacA11B.1.1.3060.000438
ORF1ab/nsp4419T419TacCacT11B.1.1.3480.000796
ORF1ab/nsp4419T419TacCacT11B.1.1.4040.015873
ORF1ab/nsp4419T419TacCacT11B.1.1.700.000341
ORF1ab/nsp4419T419TacCacT11B.1.1600.000031
ORF1ab/nsp4419T419TacCacA11B.1.177.170.000821
ORF1ab/nsp4419T419TacCacA11B.1.177.180.00116
ORF1ab/nsp4419T419TacCacT11B.1.177.810.000189
ORF1ab/nsp4419T419TacCacT11B.1.230.006061
ORF1ab/nsp4419T419TacCacT11B.1.2350.002519
ORF1ab/nsp4419T419TacCacT11B.1.2410.000812
ORF1ab/nsp4419T419TacCacT11B.1.2650.001271
ORF1ab/nsp4419T419TacCacT11B.1.36.100.004785
ORF1ab/nsp4419T419TacCacT11B.1.4220.000812
ORF1ab/nsp4419T419TacCacT11B.1.5170.000427
ORF1ab/nsp4419T419TacCacT11B.1.5640.000426
ORF1ab/nsp4419T419TacCacT11B.1.5750.000303
ORF1ab/nsp4419T419TacCacA11B.1.5760.000907
ORF1ab/nsp4419T419TacCacA11B.1.5950.000261
ORF1ab/nsp4419T419TacCacT11B.1.6090.000479
ORF1ab/nsp4419T419TacCacT11B.1.6300.005236
ORF1ab/nsp4419T419TacCacT11B.1.6320.006711
ORF1ab/nsp4419T419TacCacT11C.350.000774
ORF1ab/nsp4419T419TacCacT11P.1.10.000318
ORF1ab/nsp4419T419TacCacT11P.1.100.000269
ORF1ab/nsp4419T419TacCacA11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.