CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = T37T

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp437T37TT2800TsynacTacC3111790.5755638663-8665
ORF1ab/nsp437T37TT2800TsynacTacA311820.2636668663-8665
ORF1ab/nsp437T37TT2800TsynacTacG311500.1607728663-8665

Details of the mutation T37T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp437T37TacTacC179311All0.000034
ORF1ab/nsp437T37TacTacA82311All0.000016
ORF1ab/nsp437T37TacTacG50311All0.00001
ORF1ab/nsp437T37TacTacC7274AY.40.000112
ORF1ab/nsp437T37TacTacA174AY.40.000002
ORF1ab/nsp437T37TacTacG174AY.40.000002
ORF1ab/nsp437T37TacTacG3436AY.440.000207
ORF1ab/nsp437T37TacTacC236AY.440.000012
ORF1ab/nsp437T37TacTacC2828B.1.1770.000369
ORF1ab/nsp437T37TacTacA2121AY.850.008971
ORF1ab/nsp437T37TacTacC1319B.1.1.70.000012
ORF1ab/nsp437T37TacTacA619B.1.1.70.000005
ORF1ab/nsp437T37TacTacA910B.1.10.000163
ORF1ab/nsp437T37TacTacG110B.1.10.000018
ORF1ab/nsp437T37TacTacC78AY.290.00011
ORF1ab/nsp437T37TacTacA18AY.290.000016
ORF1ab/nsp437T37TacTacC88B.1.3110.002197
ORF1ab/nsp437T37TacTacC37AY.30.00003
ORF1ab/nsp437T37TacTacG37AY.30.00003
ORF1ab/nsp437T37TacTacA17AY.30.00001
ORF1ab/nsp437T37TacTacA77B.1.1.4200.007042
ORF1ab/nsp437T37TacTacC66AY.1000.000276
ORF1ab/nsp437T37TacTacA55AY.390.000124
ORF1ab/nsp437T37TacTacG45AY.50.000083
ORF1ab/nsp437T37TacTacC15AY.50.000021
ORF1ab/nsp437T37TacTacG35B.10.000027
ORF1ab/nsp437T37TacTacA15B.10.000009
ORF1ab/nsp437T37TacTacC15B.10.000009
ORF1ab/nsp437T37TacTacC35B.1.617.20.000011
ORF1ab/nsp437T37TacTacA25B.1.617.20.000008
ORF1ab/nsp437T37TacTacC240.111111
ORF1ab/nsp437T37TacTacA240.111111
ORF1ab/nsp437T37TacTacA34AY.1030.000019
ORF1ab/nsp437T37TacTacC14AY.1030.000006
ORF1ab/nsp437T37TacTacC23AY.200.000078
ORF1ab/nsp437T37TacTacA13AY.200.000039
ORF1ab/nsp437T37TacTacA33AY.300.001187
ORF1ab/nsp437T37TacTacA23AY.430.000009
ORF1ab/nsp437T37TacTacC13AY.430.000004
ORF1ab/nsp437T37TacTacA12AY.23.10.000417
ORF1ab/nsp437T37TacTacC12AY.23.10.000417
ORF1ab/nsp437T37TacTacC22AY.450.000243
ORF1ab/nsp437T37TacTacC22AY.740.000231
ORF1ab/nsp437T37TacTacA22B.1.1.2630.003115
ORF1ab/nsp437T37TacTacG22B.1.1.3170.000823
ORF1ab/nsp437T37TacTacA22B.1.20.000018
ORF1ab/nsp437T37TacTacC22B.1.2210.000142
ORF1ab/nsp437T37TacTacC22B.1.5260.000047
ORF1ab/nsp437T37TacTacC22D.20.00015
ORF1ab/nsp437T37TacTacC11A.2.40.003367
ORF1ab/nsp437T37TacTacC11AY.1190.000035
ORF1ab/nsp437T37TacTacA11AY.1210.000135
ORF1ab/nsp437T37TacTacC11AY.230.00007
ORF1ab/nsp437T37TacTacA11AY.250.000006
ORF1ab/nsp437T37TacTacA11AY.330.000067
ORF1ab/nsp437T37TacTacA11AY.34.10.00051
ORF1ab/nsp437T37TacTacA11AY.39.20.001541
ORF1ab/nsp437T37TacTacC11AY.4.20.000022
ORF1ab/nsp437T37TacTacA11AY.460.000104
ORF1ab/nsp437T37TacTacC11AY.46.20.000635
ORF1ab/nsp437T37TacTacA11AY.5.30.000337
ORF1ab/nsp437T37TacTacC11AY.550.000917
ORF1ab/nsp437T37TacTacC11AY.75.10.00018
ORF1ab/nsp437T37TacTacG11AY.800.001129
ORF1ab/nsp437T37TacTacA11AY.9.20.000037
ORF1ab/nsp437T37TacTacA11AY.920.000287
ORF1ab/nsp437T37TacTacC11B0.000128
ORF1ab/nsp437T37TacTacC11B.1.1.3770.001381
ORF1ab/nsp437T37TacTacC11B.1.1.5190.00004
ORF1ab/nsp437T37TacTacG11B.1.177.810.000189
ORF1ab/nsp437T37TacTacC11B.1.36.310.001751
ORF1ab/nsp437T37TacTacA11B.1.3690.000285
ORF1ab/nsp437T37TacTacC11B.1.4290.000024
ORF1ab/nsp437T37TacTacA11B.1.466.20.000391
ORF1ab/nsp437T37TacTacC11B.1.5900.004545
ORF1ab/nsp437T37TacTacC11B.1.6060.006024
ORF1ab/nsp437T37TacTacC11B.1.6190.000871
ORF1ab/nsp437T37TacTacC11P.10.000016
ORF1ab/nsp437T37TacTacC11P.1.140.000048
ORF1ab/nsp437T37TacTacA11P.50.013699
ORF1ab/nsp437T37TacTacC11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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