CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = T143T

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4143T143TT2906TsynacTacG837478590.93858981-8983
ORF1ab/nsp4143T143TT2906TsynacTacA83743440.04107958981-8983
ORF1ab/nsp4143T143TT2906TsynacTacC83741710.02042038981-8983

Details of the mutation T143T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4143T143TacTacG78598374All0.001503
ORF1ab/nsp4143T143TacTacA3448374All0.000066
ORF1ab/nsp4143T143TacTacC1718374All0.000033
ORF1ab/nsp4143T143TacTacG62686268B.1.2210.445234
ORF1ab/nsp4143T143TacTacG11881188B.1.221.30.99
ORF1ab/nsp4143T143TacTacA239281B.1.1.70.000214
ORF1ab/nsp4143T143TacTacC38281B.1.1.70.000034
ORF1ab/nsp4143T143TacTacG4281B.1.1.70.000004
ORF1ab/nsp4143T143TacTacG242242B.1.221.20.971888
ORF1ab/nsp4143T143TacTacG5663B.10.000513
ORF1ab/nsp4143T143TacTacA663B.10.000055
ORF1ab/nsp4143T143TacTacC163B.10.000009
ORF1ab/nsp4143T143TacTacA1729B.1.617.20.000064
ORF1ab/nsp4143T143TacTacC1029B.1.617.20.000038
ORF1ab/nsp4143T143TacTacG229B.1.617.20.000008
ORF1ab/nsp4143T143TacTacA2325AY.9.10.001926
ORF1ab/nsp4143T143TacTacC225AY.9.10.000167
ORF1ab/nsp4143T143TacTacG1225B.1.1770.000158
ORF1ab/nsp4143T143TacTacA1125B.1.1770.000145
ORF1ab/nsp4143T143TacTacC225B.1.1770.000026
ORF1ab/nsp4143T143TacTacC2323AY.300.009102
ORF1ab/nsp4143T143TacTacC1919AY.75.10.003426
ORF1ab/nsp4143T143TacTacG1818AY.1030.000112
ORF1ab/nsp4143T143TacTacC1515B.1.177.770.010893
ORF1ab/nsp4143T143TacTacA813P.10.000126
ORF1ab/nsp4143T143TacTacC313P.10.000047
ORF1ab/nsp4143T143TacTacG213P.10.000032
ORF1ab/nsp4143T143TacTacC1010AY.30.000099
ORF1ab/nsp4143T143TacTacG710B.1.10.000127
ORF1ab/nsp4143T143TacTacA210B.1.10.000036
ORF1ab/nsp4143T143TacTacC110B.1.10.000018
ORF1ab/nsp4143T143TacTacG910B.1.2100.01919
ORF1ab/nsp4143T143TacTacC110B.1.2100.002132
ORF1ab/nsp4143T143TacTacC79B.1.4290.000165
ORF1ab/nsp4143T143TacTacG29B.1.4290.000047
ORF1ab/nsp4143T143TacTacG77B.1.160.320.030043
ORF1ab/nsp4143T143TacTacG77B.1.36.10.007982
ORF1ab/nsp4143T143TacTacG37Q.10.000379
ORF1ab/nsp4143T143TacTacC37Q.10.000379
ORF1ab/nsp4143T143TacTacA17Q.10.000126
ORF1ab/nsp4143T143TacTacG46B.1.1600.000125
ORF1ab/nsp4143T143TacTacA26B.1.1600.000062
ORF1ab/nsp4143T143TacTacA56B.1.5260.000118
ORF1ab/nsp4143T143TacTacC16B.1.5260.000024
ORF1ab/nsp4143T143TacTacA35AY.1000.000138
ORF1ab/nsp4143T143TacTacC25AY.1000.000092
ORF1ab/nsp4143T143TacTacC45AY.40.000006
ORF1ab/nsp4143T143TacTacA15AY.40.000002
ORF1ab/nsp4143T143TacTacA35AY.440.000018
ORF1ab/nsp4143T143TacTacC25AY.440.000012
ORF1ab/nsp4143T143TacTacC35B.1.20.000026
ORF1ab/nsp4143T143TacTacG15B.1.20.000009
ORF1ab/nsp4143T143TacTacA15B.1.20.000009
ORF1ab/nsp4143T143TacTacC44B.1.1.2770.003035
ORF1ab/nsp4143T143TacTacC33AY.98.10.000145
ORF1ab/nsp4143T143TacTacA22A.210.00554
ORF1ab/nsp4143T143TacTacC22AY.200.000078
ORF1ab/nsp4143T143TacTacG12AY.260.000028
ORF1ab/nsp4143T143TacTacC12AY.260.000028
ORF1ab/nsp4143T143TacTacA22AY.430.000009
ORF1ab/nsp4143T143TacTacG12AY.610.000105
ORF1ab/nsp4143T143TacTacC12AY.610.000105
ORF1ab/nsp4143T143TacTacG22B.1.1.3510.005587
ORF1ab/nsp4143T143TacTacC22B.1.177.210.000153
ORF1ab/nsp4143T143TacTacG22B.1.177.860.000367
ORF1ab/nsp4143T143TacTacA22B.1.36.290.001035
ORF1ab/nsp4143T143TacTacC22B.1.3990.003868
ORF1ab/nsp4143T143TacTacA12B.1.4270.00005
ORF1ab/nsp4143T143TacTacC12B.1.4270.00005
ORF1ab/nsp4143T143TacTacA22B.1.5060.047619
ORF1ab/nsp4143T143TacTacC22B.1.5750.000607
ORF1ab/nsp4143T143TacTacA22C.320.046512
ORF1ab/nsp4143T143TacTacA11A.20.000662
ORF1ab/nsp4143T143TacTacG11AY.1140.000231
ORF1ab/nsp4143T143TacTacC11AY.1160.000287
ORF1ab/nsp4143T143TacTacA11AY.210.001898
ORF1ab/nsp4143T143TacTacG11AY.230.00007
ORF1ab/nsp4143T143TacTacA11AY.23.10.000417
ORF1ab/nsp4143T143TacTacA11AY.350.000233
ORF1ab/nsp4143T143TacTacA11AY.50.000021
ORF1ab/nsp4143T143TacTacC11AY.5.30.000337
ORF1ab/nsp4143T143TacTacC11AY.520.000814
ORF1ab/nsp4143T143TacTacG11AY.620.000436
ORF1ab/nsp4143T143TacTacA11AY.90.000068
ORF1ab/nsp4143T143TacTacG11B.1.1.1620.029412
ORF1ab/nsp4143T143TacTacC11B.1.1.2320.001815
ORF1ab/nsp4143T143TacTacA11B.1.1.280.000311
ORF1ab/nsp4143T143TacTacG11B.1.1.3020.002075
ORF1ab/nsp4143T143TacTacG11B.1.1.390.00051
ORF1ab/nsp4143T143TacTacG11B.1.1.510.001718
ORF1ab/nsp4143T143TacTacA11B.1.1.700.000341
ORF1ab/nsp4143T143TacTacG11B.1.160.160.000929
ORF1ab/nsp4143T143TacTacG11B.1.160.260.002421
ORF1ab/nsp4143T143TacTacG11B.1.177.120.000152
ORF1ab/nsp4143T143TacTacG11B.1.177.430.001477
ORF1ab/nsp4143T143TacTacG11B.1.177.440.000519
ORF1ab/nsp4143T143TacTacG11B.1.177.730.000566
ORF1ab/nsp4143T143TacTacG11B.1.177.810.000189
ORF1ab/nsp4143T143TacTacG11B.1.177.840.006667
ORF1ab/nsp4143T143TacTacG11B.1.2430.00007
ORF1ab/nsp4143T143TacTacG11B.1.2580.000067
ORF1ab/nsp4143T143TacTacG11B.1.258.110.000396
ORF1ab/nsp4143T143TacTacC11B.1.3510.00003
ORF1ab/nsp4143T143TacTacA11B.1.36.80.001
ORF1ab/nsp4143T143TacTacG11B.1.4730.019231
ORF1ab/nsp4143T143TacTacG11B.1.6090.000479
ORF1ab/nsp4143T143TacTacG11B.1.6210.000089
ORF1ab/nsp4143T143TacTacC11C.370.000116
ORF1ab/nsp4143T143TacTacA11D.20.000075
ORF1ab/nsp4143T143TacTacA11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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