CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = S432G

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4432S432GS3195GnonsynAgtGgt1896189619848-9850

Details of the mutation S432G within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4432S432GAgtGgt18961896All0.000363
ORF1ab/nsp4432S432GAgtGgt518518B.1.1.70.000464
ORF1ab/nsp4432S432GAgtGgt221221AY.4.20.004793
ORF1ab/nsp4432S432GAgtGgt161161AY.40.000251
ORF1ab/nsp4432S432GAgtGgt150150S.10.742574
ORF1ab/nsp4432S432GAgtGgt8484B.1.1.2170.305455
ORF1ab/nsp4432S432GAgtGgt5656B.1.1770.000737
ORF1ab/nsp4432S432GAgtGgt5555B.1.617.20.000207
ORF1ab/nsp4432S432GAgtGgt4444AY.430.000195
ORF1ab/nsp4432S432GAgtGgt4444AY.440.000268
ORF1ab/nsp4432S432GAgtGgt4141B.1.20.000361
ORF1ab/nsp4432S432GAgtGgt3535AY.1030.000217
ORF1ab/nsp4432S432GAgtGgt3434P.10.000536
ORF1ab/nsp4432S432GAgtGgt2626AY.1020.000689
ORF1ab/nsp4432S432GAgtGgt2424AY.250.000144
ORF1ab/nsp4432S432GAgtGgt2424AY.30.000239
ORF1ab/nsp4432S432GAgtGgt2222B.1.1.5190.000874
ORF1ab/nsp4432S432GAgtGgt2121B.10.000192
ORF1ab/nsp4432S432GAgtGgt1919B.1.10.000345
ORF1ab/nsp4432S432GAgtGgt1818B.1.2580.001198
ORF1ab/nsp4432S432GAgtGgt1616B.1.3510.000476
ORF1ab/nsp4432S432GAgtGgt1414B.1.1.3690.006247
ORF1ab/nsp4432S432GAgtGgt1212B.1.1600.000374
ORF1ab/nsp4432S432GAgtGgt99AY.920.002585
ORF1ab/nsp4432S432GAgtGgt99B.1.1.2940.011392
ORF1ab/nsp4432S432GAgtGgt88AY.1160.002294
ORF1ab/nsp4432S432GAgtGgt88AY.1200.000297
ORF1ab/nsp4432S432GAgtGgt88AY.50.000165
ORF1ab/nsp4432S432GAgtGgt88B.1.1.1530.008762
ORF1ab/nsp4432S432GAgtGgt88B.1.5260.000188
ORF1ab/nsp4432S432GAgtGgt77AY.290.00011
ORF1ab/nsp4432S432GAgtGgt77B.1.4270.000353
ORF1ab/nsp4432S432GAgtGgt77B.1.5960.00061
ORF1ab/nsp4432S432GAgtGgt66AY.330.000401
ORF1ab/nsp4432S432GAgtGgt66AY.390.000148
ORF1ab/nsp4432S432GAgtGgt66B.1.220.007905
ORF1ab/nsp4432S432GAgtGgt66B.1.2430.000418
ORF1ab/nsp4432S432GAgtGgt66B.1.4290.000141
ORF1ab/nsp4432S432GAgtGgt66Q.10.000758
ORF1ab/nsp4432S432GAgtGgt55AY.60.000206
ORF1ab/nsp4432S432GAgtGgt55B.1.6210.000443
ORF1ab/nsp4432S432GAgtGgt55R.10.00045
ORF1ab/nsp4432S432GAgtGgt44AY.340.000388
ORF1ab/nsp4432S432GAgtGgt44B.1.1.2140.000222
ORF1ab/nsp4432S432GAgtGgt44B.1.5770.002749
ORF1ab/nsp4432S432GAgtGgt33AY.1140.000693
ORF1ab/nsp4432S432GAgtGgt33AY.200.000117
ORF1ab/nsp4432S432GAgtGgt33AY.4.2.10.000447
ORF1ab/nsp4432S432GAgtGgt33AY.420.000121
ORF1ab/nsp4432S432GAgtGgt33AY.46.60.000217
ORF1ab/nsp4432S432GAgtGgt33AY.840.001312
ORF1ab/nsp4432S432GAgtGgt33B.1.1.1890.004539
ORF1ab/nsp4432S432GAgtGgt33B.1.2340.000396
ORF1ab/nsp4432S432GAgtGgt33B.1.4250.008982
ORF1ab/nsp4432S432GAgtGgt33P.1.140.000143
ORF1ab/nsp4432S432GAgtGgt22A.2.50.000998
ORF1ab/nsp4432S432GAgtGgt22A.290.010638
ORF1ab/nsp4432S432GAgtGgt22AY.1070.000932
ORF1ab/nsp4432S432GAgtGgt22AY.46.40.000329
ORF1ab/nsp4432S432GAgtGgt22AY.980.000158
ORF1ab/nsp4432S432GAgtGgt22AY.99.20.000184
ORF1ab/nsp4432S432GAgtGgt22B.1.1.2220.000408
ORF1ab/nsp4432S432GAgtGgt22B.1.1.330.000842
ORF1ab/nsp4432S432GAgtGgt22B.1.1.3540.008772
ORF1ab/nsp4432S432GAgtGgt22B.1.1.630.000772
ORF1ab/nsp4432S432GAgtGgt22B.1.177.580.002663
ORF1ab/nsp4432S432GAgtGgt22B.1.177.790.004684
ORF1ab/nsp4432S432GAgtGgt22B.1.2400.000431
ORF1ab/nsp4432S432GAgtGgt22B.1.4700.002809
ORF1ab/nsp4432S432GAgtGgt22B.1.4990.002101
ORF1ab/nsp4432S432GAgtGgt22B.1.5950.000522
ORF1ab/nsp4432S432GAgtGgt22B.30.001661
ORF1ab/nsp4432S432GAgtGgt22C.360.001821
ORF1ab/nsp4432S432GAgtGgt22D.20.00015
ORF1ab/nsp4432S432GAgtGgt22P.20.000373
ORF1ab/nsp4432S432GAgtGgt11A0.000387
ORF1ab/nsp4432S432GAgtGgt11A.23.10.000704
ORF1ab/nsp4432S432GAgtGgt11AE.30.032258
ORF1ab/nsp4432S432GAgtGgt11AY.1100.000113
ORF1ab/nsp4432S432GAgtGgt11AY.160.00038
ORF1ab/nsp4432S432GAgtGgt11AY.230.00007
ORF1ab/nsp4432S432GAgtGgt11AY.39.10.00004
ORF1ab/nsp4432S432GAgtGgt11AY.460.000104
ORF1ab/nsp4432S432GAgtGgt11AY.46.20.000635
ORF1ab/nsp4432S432GAgtGgt11AY.540.000095
ORF1ab/nsp4432S432GAgtGgt11AY.580.000907
ORF1ab/nsp4432S432GAgtGgt11AY.70.000196
ORF1ab/nsp4432S432GAgtGgt11AY.7.10.000113
ORF1ab/nsp4432S432GAgtGgt11AY.7.20.000559
ORF1ab/nsp4432S432GAgtGgt11AY.75.10.00018
ORF1ab/nsp4432S432GAgtGgt11AY.98.10.000048
ORF1ab/nsp4432S432GAgtGgt11AY.990.001049
ORF1ab/nsp4432S432GAgtGgt11B0.000128
ORF1ab/nsp4432S432GAgtGgt11B.1.1.1210.002427
ORF1ab/nsp4432S432GAgtGgt11B.1.1.2160.00089
ORF1ab/nsp4432S432GAgtGgt11B.1.1.2880.001916
ORF1ab/nsp4432S432GAgtGgt11B.1.1.2970.002237
ORF1ab/nsp4432S432GAgtGgt11B.1.1.3720.000689
ORF1ab/nsp4432S432GAgtGgt11B.1.1.3740.002375
ORF1ab/nsp4432S432GAgtGgt11B.1.1.3930.111111
ORF1ab/nsp4432S432GAgtGgt11B.1.1.5250.005464
ORF1ab/nsp4432S432GAgtGgt11B.1.130.002375
ORF1ab/nsp4432S432GAgtGgt11B.1.1700.00431
ORF1ab/nsp4432S432GAgtGgt11B.1.177.70.000165
ORF1ab/nsp4432S432GAgtGgt11B.1.177.800.001912
ORF1ab/nsp4432S432GAgtGgt11B.1.2010.005682
ORF1ab/nsp4432S432GAgtGgt11B.1.258.160.001637
ORF1ab/nsp4432S432GAgtGgt11B.1.36.180.00042
ORF1ab/nsp4432S432GAgtGgt11B.1.5170.000427
ORF1ab/nsp4432S432GAgtGgt11B.1.5490.007194
ORF1ab/nsp4432S432GAgtGgt11B.1.5670.003333
ORF1ab/nsp4432S432GAgtGgt11B.1.5870.001898
ORF1ab/nsp4432S432GAgtGgt11B.1.6090.000479
ORF1ab/nsp4432S432GAgtGgt11B.1.617.10.000129
ORF1ab/nsp4432S432GAgtGgt11B.400.000364
ORF1ab/nsp4432S432GAgtGgt11C.180.002591
ORF1ab/nsp4432S432GAgtGgt11P.1.10.000318
ORF1ab/nsp4432S432GAgtGgt11P.1.100.000269
ORF1ab/nsp4432S432GAgtGgt11P.1.40.000977
ORF1ab/nsp4432S432GAgtGgt11P.1.70.000319

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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