CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = N131N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4131N131NN2894NsynaaCaaT435024350218945-8947

Details of the mutation N131N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4131N131NaaCaaT4350243502All0.00832
ORF1ab/nsp4131N131NaaCaaT3999039990B.1.4290.940919
ORF1ab/nsp4131N131NaaCaaT878878AY.4.30.739057
ORF1ab/nsp4131N131NaaCaaT580580B.10.005313
ORF1ab/nsp4131N131NaaCaaT470470B.1.4270.023734
ORF1ab/nsp4131N131NaaCaaT306306B.1.1.70.000274
ORF1ab/nsp4131N131NaaCaaT260260AY.40.000405
ORF1ab/nsp4131N131NaaCaaT100100AY.440.000609
ORF1ab/nsp4131N131NaaCaaT8282B.1.429.10.987952
ORF1ab/nsp4131N131NaaCaaT6868AY.430.000301
ORF1ab/nsp4131N131NaaCaaT5252B.1.20.000458
ORF1ab/nsp4131N131NaaCaaT4646B.1.617.20.000173
ORF1ab/nsp4131N131NaaCaaT3737AY.200.001438
ORF1ab/nsp4131N131NaaCaaT3737B.1.1.2200.068773
ORF1ab/nsp4131N131NaaCaaT3131P.10.000488
ORF1ab/nsp4131N131NaaCaaT2929B.1.5260.000682
ORF1ab/nsp4131N131NaaCaaT2828B.1.10.000508
ORF1ab/nsp4131N131NaaCaaT2727AY.250.000162
ORF1ab/nsp4131N131NaaCaaT2727B.1.1600.000842
ORF1ab/nsp4131N131NaaCaaT2727B.1.3110.007414
ORF1ab/nsp4131N131NaaCaaT1919AY.1030.000118
ORF1ab/nsp4131N131NaaCaaT1717AY.1130.002421
ORF1ab/nsp4131N131NaaCaaT1414B.1.2390.017094
ORF1ab/nsp4131N131NaaCaaT1313B.1.1.5190.000516
ORF1ab/nsp4131N131NaaCaaT1212B.1.5960.001046
ORF1ab/nsp4131N131NaaCaaT1111AY.30.000109
ORF1ab/nsp4131N131NaaCaaT1111AY.39.10.000436
ORF1ab/nsp4131N131NaaCaaT1111P.20.002053
ORF1ab/nsp4131N131NaaCaaT1010B.1.6180.040323
ORF1ab/nsp4131N131NaaCaaT99A.2.50.004491
ORF1ab/nsp4131N131NaaCaaT99AY.4.50.000967
ORF1ab/nsp4131N131NaaCaaT99B.1.1.280.002801
ORF1ab/nsp4131N131NaaCaaT99B.1.1890.038627
ORF1ab/nsp4131N131NaaCaaT88B.1.177.730.00453
ORF1ab/nsp4131N131NaaCaaT77AY.1190.000247
ORF1ab/nsp4131N131NaaCaaT77B.1.1.3160.006475
ORF1ab/nsp4131N131NaaCaaT77B.1.5610.002779
ORF1ab/nsp4131N131NaaCaaT66AY.120.10.001926
ORF1ab/nsp4131N131NaaCaaT66B.1.1770.000079
ORF1ab/nsp4131N131NaaCaaT66B.1.4160.007614
ORF1ab/nsp4131N131NaaCaaT55AY.1070.00233
ORF1ab/nsp4131N131NaaCaaT55B.1.5950.001305
ORF1ab/nsp4131N131NaaCaaT55B.1.621.10.002529
ORF1ab/nsp4131N131NaaCaaT44AY.1020.000106
ORF1ab/nsp4131N131NaaCaaT44AY.1200.000149
ORF1ab/nsp4131N131NaaCaaT44AY.230.000279
ORF1ab/nsp4131N131NaaCaaT44AY.390.000099
ORF1ab/nsp4131N131NaaCaaT44AY.4.20.000087
ORF1ab/nsp4131N131NaaCaaT44B.1.1.2410.008282
ORF1ab/nsp4131N131NaaCaaT44B.1.1.3980.012903
ORF1ab/nsp4131N131NaaCaaT44B.1.1.5070.034783
ORF1ab/nsp4131N131NaaCaaT44B.1.2210.000284
ORF1ab/nsp4131N131NaaCaaT44B.1.36.360.002408
ORF1ab/nsp4131N131NaaCaaT44B.1.6230.002146
ORF1ab/nsp4131N131NaaCaaT33AY.1210.000406
ORF1ab/nsp4131N131NaaCaaT33AY.750.000168
ORF1ab/nsp4131N131NaaCaaT33AY.760.014493
ORF1ab/nsp4131N131NaaCaaT33B.1.1.3180.000905
ORF1ab/nsp4131N131NaaCaaT33B.1.2320.001612
ORF1ab/nsp4131N131NaaCaaT33B.1.3510.000089
ORF1ab/nsp4131N131NaaCaaT33B.1.3670.002377
ORF1ab/nsp4131N131NaaCaaT33B.1.6090.001438
ORF1ab/nsp4131N131NaaCaaT33P.1.170.000485
ORF1ab/nsp4131N131NaaCaaT220.111111
ORF1ab/nsp4131N131NaaCaaT22A.10.000564
ORF1ab/nsp4131N131NaaCaaT22A.2.5.20.003145
ORF1ab/nsp4131N131NaaCaaT22A.23.10.001408
ORF1ab/nsp4131N131NaaCaaT22AE.80.000978
ORF1ab/nsp4131N131NaaCaaT22AY.1170.000169
ORF1ab/nsp4131N131NaaCaaT22AY.140.000176
ORF1ab/nsp4131N131NaaCaaT22AY.260.000057
ORF1ab/nsp4131N131NaaCaaT22AY.3.10.000171
ORF1ab/nsp4131N131NaaCaaT22AY.330.000134
ORF1ab/nsp4131N131NaaCaaT22AY.420.00008
ORF1ab/nsp4131N131NaaCaaT22AY.460.000208
ORF1ab/nsp4131N131NaaCaaT22AY.470.000062
ORF1ab/nsp4131N131NaaCaaT22AY.50.000041
ORF1ab/nsp4131N131NaaCaaT22AY.850.000854
ORF1ab/nsp4131N131NaaCaaT22AY.98.10.000097
ORF1ab/nsp4131N131NaaCaaT22B.1.1.1890.003026
ORF1ab/nsp4131N131NaaCaaT22B.1.1.2070.002364
ORF1ab/nsp4131N131NaaCaaT22B.1.1.2290.011494
ORF1ab/nsp4131N131NaaCaaT22B.1.160.70.004158
ORF1ab/nsp4131N131NaaCaaT22B.1.2340.000264
ORF1ab/nsp4131N131NaaCaaT22B.1.2400.000431
ORF1ab/nsp4131N131NaaCaaT22B.1.2430.000139
ORF1ab/nsp4131N131NaaCaaT22B.1.258.90.01
ORF1ab/nsp4131N131NaaCaaT22B.1.4040.002604
ORF1ab/nsp4131N131NaaCaaT22B.1.5250.000226
ORF1ab/nsp4131N131NaaCaaT22B.1.5680.002222
ORF1ab/nsp4131N131NaaCaaT22B.1.575.10.004878
ORF1ab/nsp4131N131NaaCaaT22B.1.5800.00813
ORF1ab/nsp4131N131NaaCaaT22D.20.00015
ORF1ab/nsp4131N131NaaCaaT22P.1.120.000968
ORF1ab/nsp4131N131NaaCaaT22P.1.150.000465
ORF1ab/nsp4131N131NaaCaaT22R.10.00018
ORF1ab/nsp4131N131NaaCaaT11A.20.000662
ORF1ab/nsp4131N131NaaCaaT11A.210.00277
ORF1ab/nsp4131N131NaaCaaT11AY.130.000161
ORF1ab/nsp4131N131NaaCaaT11AY.16.10.00047
ORF1ab/nsp4131N131NaaCaaT11AY.270.000065
ORF1ab/nsp4131N131NaaCaaT11AY.4.40.000409
ORF1ab/nsp4131N131NaaCaaT11AY.400.000964
ORF1ab/nsp4131N131NaaCaaT11AY.450.000122
ORF1ab/nsp4131N131NaaCaaT11AY.46.20.000635
ORF1ab/nsp4131N131NaaCaaT11AY.540.000095
ORF1ab/nsp4131N131NaaCaaT11AY.590.00053
ORF1ab/nsp4131N131NaaCaaT11AY.660.00107
ORF1ab/nsp4131N131NaaCaaT11AY.7.20.000559
ORF1ab/nsp4131N131NaaCaaT11AY.75.10.00018
ORF1ab/nsp4131N131NaaCaaT11AY.840.000437
ORF1ab/nsp4131N131NaaCaaT11AY.880.000884
ORF1ab/nsp4131N131NaaCaaT11AY.9.20.000037
ORF1ab/nsp4131N131NaaCaaT11AY.950.000761
ORF1ab/nsp4131N131NaaCaaT11AZ.20.000821
ORF1ab/nsp4131N131NaaCaaT11B.1.1.1410.002012
ORF1ab/nsp4131N131NaaCaaT11B.1.1.1760.000439
ORF1ab/nsp4131N131NaaCaaT11B.1.1.2140.000055
ORF1ab/nsp4131N131NaaCaaT11B.1.1.2220.000204
ORF1ab/nsp4131N131NaaCaaT11B.1.1.2340.012048
ORF1ab/nsp4131N131NaaCaaT11B.1.1.2690.001353
ORF1ab/nsp4131N131NaaCaaT11B.1.1.2770.000759
ORF1ab/nsp4131N131NaaCaaT11B.1.1.2890.002083
ORF1ab/nsp4131N131NaaCaaT11B.1.1.330.000421
ORF1ab/nsp4131N131NaaCaaT11B.1.1.3340.016393
ORF1ab/nsp4131N131NaaCaaT11B.1.1.3970.002252
ORF1ab/nsp4131N131NaaCaaT11B.1.1.4070.041667
ORF1ab/nsp4131N131NaaCaaT11B.1.1.4280.009434
ORF1ab/nsp4131N131NaaCaaT11B.1.1260.001276
ORF1ab/nsp4131N131NaaCaaT11B.1.1280.000635
ORF1ab/nsp4131N131NaaCaaT11B.1.1570.002985
ORF1ab/nsp4131N131NaaCaaT11B.1.160.120.00641
ORF1ab/nsp4131N131NaaCaaT11B.1.160.300.002976
ORF1ab/nsp4131N131NaaCaaT11B.1.177.120.000152
ORF1ab/nsp4131N131NaaCaaT11B.1.177.510.004566
ORF1ab/nsp4131N131NaaCaaT11B.1.177.530.002392
ORF1ab/nsp4131N131NaaCaaT11B.1.177.750.001041
ORF1ab/nsp4131N131NaaCaaT11B.1.177.810.000189
ORF1ab/nsp4131N131NaaCaaT11B.1.1810.019608
ORF1ab/nsp4131N131NaaCaaT11B.1.2130.014925
ORF1ab/nsp4131N131NaaCaaT11B.1.2580.000067
ORF1ab/nsp4131N131NaaCaaT11B.1.258.30.001675
ORF1ab/nsp4131N131NaaCaaT11B.1.258.40.003448
ORF1ab/nsp4131N131NaaCaaT11B.1.2810.021739
ORF1ab/nsp4131N131NaaCaaT11B.1.3540.043478
ORF1ab/nsp4131N131NaaCaaT11B.1.3560.001727
ORF1ab/nsp4131N131NaaCaaT11B.1.36.290.000517
ORF1ab/nsp4131N131NaaCaaT11B.1.4050.012346
ORF1ab/nsp4131N131NaaCaaT11B.1.4370.020833
ORF1ab/nsp4131N131NaaCaaT11B.1.438.10.000107
ORF1ab/nsp4131N131NaaCaaT11B.1.4410.009615
ORF1ab/nsp4131N131NaaCaaT11B.1.5330.009615
ORF1ab/nsp4131N131NaaCaaT11B.1.5560.007519
ORF1ab/nsp4131N131NaaCaaT11B.1.5600.00463
ORF1ab/nsp4131N131NaaCaaT11B.1.6210.000089
ORF1ab/nsp4131N131NaaCaaT11B.1.6370.000073
ORF1ab/nsp4131N131NaaCaaT11B.1.940.027027
ORF1ab/nsp4131N131NaaCaaT11B.4.10.018868
ORF1ab/nsp4131N131NaaCaaT11B.60.00091
ORF1ab/nsp4131N131NaaCaaT11C.160.00106
ORF1ab/nsp4131N131NaaCaaT11C.350.000774
ORF1ab/nsp4131N131NaaCaaT11C.370.000116
ORF1ab/nsp4131N131NaaCaaT11K.30.006173
ORF1ab/nsp4131N131NaaCaaT11P.1.10.000318
ORF1ab/nsp4131N131NaaCaaT11P.1.100.000269
ORF1ab/nsp4131N131NaaCaaT11P.1.140.000048
ORF1ab/nsp4131N131NaaCaaT11P.1.160.000374
ORF1ab/nsp4131N131NaaCaaT11Q.10.000126
ORF1ab/nsp4131N131NaaCaaT11Q.30.000145
ORF1ab/nsp4131N131NaaCaaT11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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