CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = L323L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4323L323LL3086LsynctTctC93740.7956999521-9523
ORF1ab/nsp4323L323LL3086LsynctTctA93140.1505389521-9523
ORF1ab/nsp4323L323LL3086LsynctTctG9340.04301089521-9523
ORF1ab/nsp4323L323LL3086LsynCtTTtA9310.01075279521-9523

Details of the mutation L323L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4323L323LctTctC7493All0.000014
ORF1ab/nsp4323L323LctTctA1493All0.000003
ORF1ab/nsp4323L323LctTctG493All0.000001
ORF1ab/nsp4323L323LCtTTtA193All0
ORF1ab/nsp4323L323LctTctC1515AY.250.00009
ORF1ab/nsp4323L323LctTctC1315B.1.1.70.000012
ORF1ab/nsp4323L323LctTctA215B.1.1.70.000002
ORF1ab/nsp4323L323LctTctC88B.1.20.00007
ORF1ab/nsp4323L323LctTctC77AY.50.000145
ORF1ab/nsp4323L323LctTctA56AY.30.00005
ORF1ab/nsp4323L323LctTctC16AY.30.00001
ORF1ab/nsp4323L323LctTctG25B.1.617.20.000008
ORF1ab/nsp4323L323LctTctC25B.1.617.20.000008
ORF1ab/nsp4323L323LCtTTtA15B.1.617.20.000004
ORF1ab/nsp4323L323LctTctC44AE.80.001956
ORF1ab/nsp4323L323LctTctC34B.1.3510.000089
ORF1ab/nsp4323L323LctTctA14B.1.3510.00003
ORF1ab/nsp4323L323LctTctC33AY.40.000005
ORF1ab/nsp4323L323LctTctC33AY.440.000018
ORF1ab/nsp4323L323LctTctA33B.1.2340.000396
ORF1ab/nsp4323L323LctTctG12AY.1020.000027
ORF1ab/nsp4323L323LctTctC12AY.1020.000027
ORF1ab/nsp4323L323LctTctC22AY.260.000057
ORF1ab/nsp4323L323LctTctC22AY.390.000049
ORF1ab/nsp4323L323LctTctC12B.10.000009
ORF1ab/nsp4323L323LctTctG12B.10.000009
ORF1ab/nsp4323L323LctTctC11AY.1030.000006
ORF1ab/nsp4323L323LctTctC11AY.290.000016
ORF1ab/nsp4323L323LctTctA11AY.430.000004
ORF1ab/nsp4323L323LctTctC11AY.460.000104
ORF1ab/nsp4323L323LctTctC11AY.540.000095
ORF1ab/nsp4323L323LctTctC11AY.9.20.000037
ORF1ab/nsp4323L323LctTctC11B.1.10.000018
ORF1ab/nsp4323L323LctTctA11B.1.1.250.000569
ORF1ab/nsp4323L323LctTctC11B.1.258.170.000104
ORF1ab/nsp4323L323LctTctC11B.1.4260.001009
ORF1ab/nsp4323L323LctTctC11B.1.5250.000113
ORF1ab/nsp4323L323LctTctA11B.1.6210.000089

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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