CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = H223H

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4223H223HH2986HsyncaCcaT7684768419221-9223

Details of the mutation H223H within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4223H223HcaCcaT76847684All0.00147
ORF1ab/nsp4223H223HcaCcaT26742674B.1.1.70.002394
ORF1ab/nsp4223H223HcaCcaT611611AY.200.023747
ORF1ab/nsp4223H223HcaCcaT533533AY.430.002361
ORF1ab/nsp4223H223HcaCcaT421421AY.410.123751
ORF1ab/nsp4223H223HcaCcaT419419B.390.97669
ORF1ab/nsp4223H223HcaCcaT287287B.1.617.20.001081
ORF1ab/nsp4223H223HcaCcaT278278AY.40.000433
ORF1ab/nsp4223H223HcaCcaT223223AY.260.006313
ORF1ab/nsp4223H223HcaCcaT192192AY.250.001155
ORF1ab/nsp4223H223HcaCcaT186186A0.071981
ORF1ab/nsp4223H223HcaCcaT132132AY.440.000803
ORF1ab/nsp4223H223HcaCcaT121121B.10.001108
ORF1ab/nsp4223H223HcaCcaT9898B.581
ORF1ab/nsp4223H223HcaCcaT9696AY.1030.000596
ORF1ab/nsp4223H223HcaCcaT9393B.1.20.000819
ORF1ab/nsp4223H223HcaCcaT7676B.1.10.001379
ORF1ab/nsp4223H223HcaCcaT7070P.10.001103
ORF1ab/nsp4223H223HcaCcaT6767B.1.177.870.048763
ORF1ab/nsp4223H223HcaCcaT4848AY.30.000477
ORF1ab/nsp4223H223HcaCcaT4848AY.750.002689
ORF1ab/nsp4223H223HcaCcaT4242AY.610.004401
ORF1ab/nsp4223H223HcaCcaT3939AY.9.20.001432
ORF1ab/nsp4223H223HcaCcaT3636B.1.4290.000847
ORF1ab/nsp4223H223HcaCcaT3030B.1.5580.136986
ORF1ab/nsp4223H223HcaCcaT2626B.1.360.003793
ORF1ab/nsp4223H223HcaCcaT2323AY.390.000568
ORF1ab/nsp4223H223HcaCcaT2222AY.1050.014148
ORF1ab/nsp4223H223HcaCcaT2222B.1.1770.00029
ORF1ab/nsp4223H223HcaCcaT2121AY.90.001419
ORF1ab/nsp4223H223HcaCcaT2020AY.290.000315
ORF1ab/nsp4223H223HcaCcaT1919B0.002428
ORF1ab/nsp4223H223HcaCcaT1818AY.1020.000477
ORF1ab/nsp4223H223HcaCcaT1818AY.1110.003297
ORF1ab/nsp4223H223HcaCcaT1717B.1.5750.005158
ORF1ab/nsp4223H223HcaCcaT1717P.20.003173
ORF1ab/nsp4223H223HcaCcaT1515AY.1130.002136
ORF1ab/nsp4223H223HcaCcaT1515AY.50.00031
ORF1ab/nsp4223H223HcaCcaT1515B.1.2580.000998
ORF1ab/nsp4223H223HcaCcaT1414AY.100.007419
ORF1ab/nsp4223H223HcaCcaT1414B.1.1.250.007959
ORF1ab/nsp4223H223HcaCcaT1414B.1.4330.044728
ORF1ab/nsp4223H223HcaCcaT1414B.1.5820.006869
ORF1ab/nsp4223H223HcaCcaT1313AY.420.000523
ORF1ab/nsp4223H223HcaCcaT1212B.1.1.5190.000477
ORF1ab/nsp4223H223HcaCcaT1212C.370.001393
ORF1ab/nsp4223H223HcaCcaT1111AY.1190.000388
ORF1ab/nsp4223H223HcaCcaT1111B.1.4000.004719
ORF1ab/nsp4223H223HcaCcaT1010AY.75.10.001803
ORF1ab/nsp4223H223HcaCcaT1010B.1.1.2630.015576
ORF1ab/nsp4223H223HcaCcaT1010B.1.177.70.001649
ORF1ab/nsp4223H223HcaCcaT1010B.1.36.360.00602
ORF1ab/nsp4223H223HcaCcaT99AY.1170.000761
ORF1ab/nsp4223H223HcaCcaT99AY.1200.000335
ORF1ab/nsp4223H223HcaCcaT99AY.330.000601
ORF1ab/nsp4223H223HcaCcaT99AY.4.20.000195
ORF1ab/nsp4223H223HcaCcaT99B.1.1.2220.001836
ORF1ab/nsp4223H223HcaCcaT99B.1.3510.000268
ORF1ab/nsp4223H223HcaCcaT99P.1.140.00043
ORF1ab/nsp4223H223HcaCcaT88AY.460.000833
ORF1ab/nsp4223H223HcaCcaT88AY.470.000249
ORF1ab/nsp4223H223HcaCcaT88B.1.1.710.048485
ORF1ab/nsp4223H223HcaCcaT88B.1.6210.000708
ORF1ab/nsp4223H223HcaCcaT77AY.3.10.000597
ORF1ab/nsp4223H223HcaCcaT77AY.39.10.000277
ORF1ab/nsp4223H223HcaCcaT77AY.980.000553
ORF1ab/nsp4223H223HcaCcaT77B.1.1.2820.081395
ORF1ab/nsp4223H223HcaCcaT77B.1.1.480.020115
ORF1ab/nsp4223H223HcaCcaT77B.1.177.620.008343
ORF1ab/nsp4223H223HcaCcaT66AY.1000.000276
ORF1ab/nsp4223H223HcaCcaT66AY.270.000388
ORF1ab/nsp4223H223HcaCcaT66AY.740.000694
ORF1ab/nsp4223H223HcaCcaT66AY.98.10.000291
ORF1ab/nsp4223H223HcaCcaT66AY.99.20.000553
ORF1ab/nsp4223H223HcaCcaT66B.1.351.30.005259
ORF1ab/nsp4223H223HcaCcaT66B.1.5260.000141
ORF1ab/nsp4223H223HcaCcaT55AY.340.000485
ORF1ab/nsp4223H223HcaCcaT55AY.450.000608
ORF1ab/nsp4223H223HcaCcaT55AY.710.002375
ORF1ab/nsp4223H223HcaCcaT55AY.9.10.000419
ORF1ab/nsp4223H223HcaCcaT55B.1.2210.000355
ORF1ab/nsp4223H223HcaCcaT55B.1.3960.003529
ORF1ab/nsp4223H223HcaCcaT55P.1.10.001588
ORF1ab/nsp4223H223HcaCcaT44AY.1180.000251
ORF1ab/nsp4223H223HcaCcaT44AY.16.10.00188
ORF1ab/nsp4223H223HcaCcaT44AY.230.000279
ORF1ab/nsp4223H223HcaCcaT44AY.540.000381
ORF1ab/nsp4223H223HcaCcaT44AY.60.000165
ORF1ab/nsp4223H223HcaCcaT44B.1.1600.000125
ORF1ab/nsp4223H223HcaCcaT44B.1.177.810.000757
ORF1ab/nsp4223H223HcaCcaT44B.1.2430.000278
ORF1ab/nsp4223H223HcaCcaT44B.1.258.170.000416
ORF1ab/nsp4223H223HcaCcaT44B.1.4270.000202
ORF1ab/nsp4223H223HcaCcaT44B.1.438.10.000429
ORF1ab/nsp4223H223HcaCcaT44P.1.150.000929
ORF1ab/nsp4223H223HcaCcaT33A.2.5.20.004717
ORF1ab/nsp4223H223HcaCcaT33AY.1070.001398
ORF1ab/nsp4223H223HcaCcaT33AY.1100.000338
ORF1ab/nsp4223H223HcaCcaT33AY.1160.00086
ORF1ab/nsp4223H223HcaCcaT33AY.1210.000406
ORF1ab/nsp4223H223HcaCcaT33AY.130.000483
ORF1ab/nsp4223H223HcaCcaT33AY.550.002752
ORF1ab/nsp4223H223HcaCcaT33AY.640.001786
ORF1ab/nsp4223H223HcaCcaT33AY.690.00056
ORF1ab/nsp4223H223HcaCcaT33B.1.1.280.000934
ORF1ab/nsp4223H223HcaCcaT33B.1.1.3180.000905
ORF1ab/nsp4223H223HcaCcaT33B.1.1.3510.00838
ORF1ab/nsp4223H223HcaCcaT33B.1.177.750.003122
ORF1ab/nsp4223H223HcaCcaT33B.1.3690.000856
ORF1ab/nsp4223H223HcaCcaT33B.1.5770.002062
ORF1ab/nsp4223H223HcaCcaT33B.1.5880.00273
ORF1ab/nsp4223H223HcaCcaT33B.1.5950.000783
ORF1ab/nsp4223H223HcaCcaT33B.1.6370.000219
ORF1ab/nsp4223H223HcaCcaT33Q.30.000435
ORF1ab/nsp4223H223HcaCcaT33R.10.00027
ORF1ab/nsp4223H223HcaCcaT220.111111
ORF1ab/nsp4223H223HcaCcaT22A.2.50.000998
ORF1ab/nsp4223H223HcaCcaT22AY.360.000296
ORF1ab/nsp4223H223HcaCcaT22AY.4.50.000215
ORF1ab/nsp4223H223HcaCcaT22AY.46.60.000144
ORF1ab/nsp4223H223HcaCcaT22AY.650.001066
ORF1ab/nsp4223H223HcaCcaT22AY.680.000547
ORF1ab/nsp4223H223HcaCcaT22AY.700.000417
ORF1ab/nsp4223H223HcaCcaT22AY.850.000854
ORF1ab/nsp4223H223HcaCcaT22AY.910.001461
ORF1ab/nsp4223H223HcaCcaT22AY.920.000575
ORF1ab/nsp4223H223HcaCcaT22AZ.60.016807
ORF1ab/nsp4223H223HcaCcaT22B.1.1.3170.000823
ORF1ab/nsp4223H223HcaCcaT22B.1.1.3680.006173
ORF1ab/nsp4223H223HcaCcaT22B.1.1.4160.00181
ORF1ab/nsp4223H223HcaCcaT22B.1.1.4480.004065
ORF1ab/nsp4223H223HcaCcaT22B.1.1570.00597
ORF1ab/nsp4223H223HcaCcaT22B.1.2100.004264
ORF1ab/nsp4223H223HcaCcaT22B.1.258.140.001961
ORF1ab/nsp4223H223HcaCcaT22B.1.351.20.000605
ORF1ab/nsp4223H223HcaCcaT22B.1.6200.001892
ORF1ab/nsp4223H223HcaCcaT22B.30.001661
ORF1ab/nsp4223H223HcaCcaT22V.10.045455
ORF1ab/nsp4223H223HcaCcaT11A.20.000662
ORF1ab/nsp4223H223HcaCcaT11A.2.20.001689
ORF1ab/nsp4223H223HcaCcaT11AE.40.043478
ORF1ab/nsp4223H223HcaCcaT11AT.10.005128
ORF1ab/nsp4223H223HcaCcaT11AU.20.002421
ORF1ab/nsp4223H223HcaCcaT11AY.1060.000335
ORF1ab/nsp4223H223HcaCcaT11AY.140.000088
ORF1ab/nsp4223H223HcaCcaT11AY.20.000356
ORF1ab/nsp4223H223HcaCcaT11AY.380.000499
ORF1ab/nsp4223H223HcaCcaT11AY.39.20.001541
ORF1ab/nsp4223H223HcaCcaT11AY.46.20.000635
ORF1ab/nsp4223H223HcaCcaT11AY.480.000465
ORF1ab/nsp4223H223HcaCcaT11AY.5.30.000337
ORF1ab/nsp4223H223HcaCcaT11AY.530.000288
ORF1ab/nsp4223H223HcaCcaT11AY.580.000907
ORF1ab/nsp4223H223HcaCcaT11AY.620.000436
ORF1ab/nsp4223H223HcaCcaT11AY.660.00107
ORF1ab/nsp4223H223HcaCcaT11AY.70.000196
ORF1ab/nsp4223H223HcaCcaT11AY.730.000665
ORF1ab/nsp4223H223HcaCcaT11AY.770.001127
ORF1ab/nsp4223H223HcaCcaT11AY.840.000437
ORF1ab/nsp4223H223HcaCcaT11AY.970.001701
ORF1ab/nsp4223H223HcaCcaT11AY.990.001049
ORF1ab/nsp4223H223HcaCcaT11AZ.20.000821
ORF1ab/nsp4223H223HcaCcaT11B.1.1.1650.015385
ORF1ab/nsp4223H223HcaCcaT11B.1.1.2210.010101
ORF1ab/nsp4223H223HcaCcaT11B.1.1.2540.011236
ORF1ab/nsp4223H223HcaCcaT11B.1.1.270.00565
ORF1ab/nsp4223H223HcaCcaT11B.1.1.2840.000107
ORF1ab/nsp4223H223HcaCcaT11B.1.1.30.008696
ORF1ab/nsp4223H223HcaCcaT11B.1.1.3050.003861
ORF1ab/nsp4223H223HcaCcaT11B.1.1.3120.001912
ORF1ab/nsp4223H223HcaCcaT11B.1.1.3370.003597
ORF1ab/nsp4223H223HcaCcaT11B.1.1.390.00051
ORF1ab/nsp4223H223HcaCcaT11B.1.1.4090.002833
ORF1ab/nsp4223H223HcaCcaT11B.1.1.540.003021
ORF1ab/nsp4223H223HcaCcaT11B.1.110.30.000718
ORF1ab/nsp4223H223HcaCcaT11B.1.1280.000635
ORF1ab/nsp4223H223HcaCcaT11B.1.130.002375
ORF1ab/nsp4223H223HcaCcaT11B.1.1420.002899
ORF1ab/nsp4223H223HcaCcaT11B.1.160.160.000929
ORF1ab/nsp4223H223HcaCcaT11B.1.160.170.001701
ORF1ab/nsp4223H223HcaCcaT11B.1.1650.011905
ORF1ab/nsp4223H223HcaCcaT11B.1.177.40.000211
ORF1ab/nsp4223H223HcaCcaT11B.1.177.560.000668
ORF1ab/nsp4223H223HcaCcaT11B.1.177.650.000665
ORF1ab/nsp4223H223HcaCcaT11B.1.177.860.000183
ORF1ab/nsp4223H223HcaCcaT11B.1.221.10.002907
ORF1ab/nsp4223H223HcaCcaT11B.1.230.006061
ORF1ab/nsp4223H223HcaCcaT11B.1.2340.000132
ORF1ab/nsp4223H223HcaCcaT11B.1.258.20.004505
ORF1ab/nsp4223H223HcaCcaT11B.1.2600.003344
ORF1ab/nsp4223H223HcaCcaT11B.1.2820.014925
ORF1ab/nsp4223H223HcaCcaT11B.1.30.002618
ORF1ab/nsp4223H223HcaCcaT11B.1.3490.000715
ORF1ab/nsp4223H223HcaCcaT11B.1.3980.002976
ORF1ab/nsp4223H223HcaCcaT11B.1.4260.001009
ORF1ab/nsp4223H223HcaCcaT11B.1.4380.006536
ORF1ab/nsp4223H223HcaCcaT11B.1.4620.007246
ORF1ab/nsp4223H223HcaCcaT11B.1.5250.000113
ORF1ab/nsp4223H223HcaCcaT11B.1.5330.009615
ORF1ab/nsp4223H223HcaCcaT11B.1.5740.002151
ORF1ab/nsp4223H223HcaCcaT11B.1.5790.011236
ORF1ab/nsp4223H223HcaCcaT11B.1.5960.000087
ORF1ab/nsp4223H223HcaCcaT11B.1.6050.005952
ORF1ab/nsp4223H223HcaCcaT11B.1.6090.000479
ORF1ab/nsp4223H223HcaCcaT11B.1.6290.013333
ORF1ab/nsp4223H223HcaCcaT11B.400.000364
ORF1ab/nsp4223H223HcaCcaT11B.50.038462
ORF1ab/nsp4223H223HcaCcaT11D.20.000075
ORF1ab/nsp4223H223HcaCcaT11P.1.70.000319
ORF1ab/nsp4223H223HcaCcaT11Q.40.000455
ORF1ab/nsp4223H223HcaCcaT11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.