CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = F375S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4375F375SF3138SnonsyntTctCc16895168900.9997049677-9679
ORF1ab/nsp4375F375SF3138SnonsyntTCtCT1689540.0002367569677-9679
ORF1ab/nsp4375F375SF3138SnonsyntTCtCA1689510.00005918919677-9679

Details of the mutation F375S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4375F375StTctCc1689016895All0.00323
ORF1ab/nsp4375F375StTCtCT416895All0.000001
ORF1ab/nsp4375F375StTCtCA116895All0
ORF1ab/nsp4375F375StTctCc89328932B.1.617.20.033633
ORF1ab/nsp4375F375StTctCc41444144AY.350.965742
ORF1ab/nsp4375F375StTctCc17501750AY.480.813953
ORF1ab/nsp4375F375StTctCc610610AY.16.10.286654
ORF1ab/nsp4375F375StTctCc207208AY.440.00126
ORF1ab/nsp4375F375StTCtCT1208AY.440.000006
ORF1ab/nsp4375F375StTctCc177177AY.130.028493
ORF1ab/nsp4375F375StTctCc121121AY.1080.133407
ORF1ab/nsp4375F375StTctCc103103AY.230.007184
ORF1ab/nsp4375F375StTctCc8080B.10.000733
ORF1ab/nsp4375F375StTctCc6060AY.590.03178
ORF1ab/nsp4375F375StTctCc5858AY.920.016662
ORF1ab/nsp4375F375StTctCc5555AY.680.015056
ORF1ab/nsp4375F375StTctCc4545AY.980.003555
ORF1ab/nsp4375F375StTctCc4444AY.540.004195
ORF1ab/nsp4375F375StTctCc4040AY.660.042781
ORF1ab/nsp4375F375StTctCc3535AY.190.039909
ORF1ab/nsp4375F375StTctCc3232AY.520.026059
ORF1ab/nsp4375F375StTctCc2727AY.370.008534
ORF1ab/nsp4375F375StTctCc2526B.1.1.70.000022
ORF1ab/nsp4375F375StTCtCA126B.1.1.70.000001
ORF1ab/nsp4375F375StTctCc2626B.1.20.000229
ORF1ab/nsp4375F375StTctCc2121AY.430.000093
ORF1ab/nsp4375F375StTctCc2121AY.5.40.005811
ORF1ab/nsp4375F375StTctCc1818AY.1160.005162
ORF1ab/nsp4375F375StTctCc1516AY.1030.000093
ORF1ab/nsp4375F375StTCtCT116AY.1030.000006
ORF1ab/nsp4375F375StTctCc1313AY.40.00002
ORF1ab/nsp4375F375StTctCc1111AY.470.000342
ORF1ab/nsp4375F375StTctCc1010B.1.10.000181
ORF1ab/nsp4375F375StTctCc99AY.1210.001218
ORF1ab/nsp4375F375StTctCc99AY.550.008257
ORF1ab/nsp4375F375StTctCc88AY.240.003448
ORF1ab/nsp4375F375StTctCc88AY.750.000448
ORF1ab/nsp4375F375StTctCc88AY.770.009019
ORF1ab/nsp4375F375StTctCc88B.1.617.10.001032
ORF1ab/nsp4375F375StTctCc77AY.610.000733
ORF1ab/nsp4375F375StTctCc77AY.870.005828
ORF1ab/nsp4375F375StTctCc77B.1.177.510.031963
ORF1ab/nsp4375F375StTctCc66AY.640.003571
ORF1ab/nsp4375F375StTctCc66AY.98.10.000291
ORF1ab/nsp4375F375StTctCc66B0.000767
ORF1ab/nsp4375F375StTctCc55AY.1000.00023
ORF1ab/nsp4375F375StTctCc55AY.1180.000313
ORF1ab/nsp4375F375StTctCc55AY.30.00005
ORF1ab/nsp4375F375StTctCc55AY.450.000608
ORF1ab/nsp4375F375StTctCc55AY.560.008026
ORF1ab/nsp4375F375StTctCc44AY.200.000155
ORF1ab/nsp4375F375StTctCc44AY.250.000024
ORF1ab/nsp4375F375StTctCc44AY.670.001857
ORF1ab/nsp4375F375StTctCc44AY.780.006163
ORF1ab/nsp4375F375StTctCc44AY.880.003537
ORF1ab/nsp4375F375StTctCc44AY.9.20.000147
ORF1ab/nsp4375F375StTctCc44P.10.000063
ORF1ab/nsp4375F375StTctCc33AY.220.006276
ORF1ab/nsp4375F375StTctCc33AY.620.001307
ORF1ab/nsp4375F375StTctCc33AY.710.001425
ORF1ab/nsp4375F375StTctCc33AY.950.002283
ORF1ab/nsp4375F375StTctCc33B.1.36.290.001552
ORF1ab/nsp4375F375StTctCc33B.1.5760.00272
ORF1ab/nsp4375F375StTCtCT220.111111
ORF1ab/nsp4375F375StTctCc22AY.100.00106
ORF1ab/nsp4375F375StTctCc22AY.1010.000981
ORF1ab/nsp4375F375StTctCc22AY.110.002677
ORF1ab/nsp4375F375StTctCc22AY.120.000632
ORF1ab/nsp4375F375StTctCc22AY.530.000575
ORF1ab/nsp4375F375StTctCc22AY.700.000417
ORF1ab/nsp4375F375StTctCc22B.1.360.000292
ORF1ab/nsp4375F375StTctCc11AY.1060.000335
ORF1ab/nsp4375F375StTctCc11AY.1100.000113
ORF1ab/nsp4375F375StTctCc11AY.140.000088
ORF1ab/nsp4375F375StTctCc11AY.270.000065
ORF1ab/nsp4375F375StTctCc11AY.280.00189
ORF1ab/nsp4375F375StTctCc11AY.290.000016
ORF1ab/nsp4375F375StTctCc11AY.320.000532
ORF1ab/nsp4375F375StTctCc11AY.330.000067
ORF1ab/nsp4375F375StTctCc11AY.360.000148
ORF1ab/nsp4375F375StTctCc11AY.380.000499
ORF1ab/nsp4375F375StTctCc11AY.390.000025
ORF1ab/nsp4375F375StTctCc11AY.410.000294
ORF1ab/nsp4375F375StTctCc11AY.420.00004
ORF1ab/nsp4375F375StTctCc11AY.460.000104
ORF1ab/nsp4375F375StTctCc11AY.5.30.000337
ORF1ab/nsp4375F375StTctCc11AY.510.000909
ORF1ab/nsp4375F375StTctCc11AY.580.000907
ORF1ab/nsp4375F375StTctCc11AY.75.10.00018
ORF1ab/nsp4375F375StTctCc11AY.820.001357
ORF1ab/nsp4375F375StTctCc11AY.850.000427
ORF1ab/nsp4375F375StTctCc11AY.910.00073
ORF1ab/nsp4375F375StTctCc11AY.960.002075
ORF1ab/nsp4375F375StTctCc11AY.99.20.000092
ORF1ab/nsp4375F375StTctCc11B.1.1.1620.029412
ORF1ab/nsp4375F375StTctCc11B.1.1770.000013
ORF1ab/nsp4375F375StTctCc11B.1.177.180.00116
ORF1ab/nsp4375F375StTctCc11B.1.2060.000816
ORF1ab/nsp4375F375StTctCc11B.1.2140.003663
ORF1ab/nsp4375F375StTctCc11B.1.2580.000067
ORF1ab/nsp4375F375StTctCc11B.1.4530.003236
ORF1ab/nsp4375F375StTctCc11B.1.4590.004082
ORF1ab/nsp4375F375StTctCc11B.1.5260.000024
ORF1ab/nsp4375F375StTctCc11B.1.5960.000087
ORF1ab/nsp4375F375StTctCc11B.1.6230.000536
ORF1ab/nsp4375F375StTctCc11B.400.000364
ORF1ab/nsp4375F375StTctCc11D.20.000075

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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