CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = E177E

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4177E177EE2940EsyngaAgaG8137813719083-9085

Details of the mutation E177E within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4177E177EgaAgaG81378137All0.001556
ORF1ab/nsp4177E177EgaAgaG70427042B.1.20.062007
ORF1ab/nsp4177E177EgaAgaG227227B.1.1.70.000203
ORF1ab/nsp4177E177EgaAgaG195195B.1.5680.216667
ORF1ab/nsp4177E177EgaAgaG111111B.1.6360.744966
ORF1ab/nsp4177E177EgaAgaG7272B.1.360.010505
ORF1ab/nsp4177E177EgaAgaG7070B.1.5960.0061
ORF1ab/nsp4177E177EgaAgaG5252B.10.000476
ORF1ab/nsp4177E177EgaAgaG4949Q.30.007107
ORF1ab/nsp4177E177EgaAgaG3838AY.530.010926
ORF1ab/nsp4177E177EgaAgaG3030B.1.10.000544
ORF1ab/nsp4177E177EgaAgaG2020P.10.000315
ORF1ab/nsp4177E177EgaAgaG1818AY.440.00011
ORF1ab/nsp4177E177EgaAgaG1616AY.40.000025
ORF1ab/nsp4177E177EgaAgaG1515AY.1030.000093
ORF1ab/nsp4177E177EgaAgaG1414AY.9.20.000514
ORF1ab/nsp4177E177EgaAgaG1313AY.700.002711
ORF1ab/nsp4177E177EgaAgaG1212B.1.4270.000606
ORF1ab/nsp4177E177EgaAgaG99B.1.4290.000212
ORF1ab/nsp4177E177EgaAgaG77AY.30.00007
ORF1ab/nsp4177E177EgaAgaG77AY.430.000031
ORF1ab/nsp4177E177EgaAgaG77B.1.1.2850.045752
ORF1ab/nsp4177E177EgaAgaG77B.1.5750.002124
ORF1ab/nsp4177E177EgaAgaG66B.1.1110.007051
ORF1ab/nsp4177E177EgaAgaG55AY.1190.000177
ORF1ab/nsp4177E177EgaAgaG55AY.470.000156
ORF1ab/nsp4177E177EgaAgaG55B.1.617.20.000019
ORF1ab/nsp4177E177EgaAgaG44B.1.6090.001918
ORF1ab/nsp4177E177EgaAgaG33AY.550.002752
ORF1ab/nsp4177E177EgaAgaG33AY.9.10.000251
ORF1ab/nsp4177E177EgaAgaG33B.1.4160.003807
ORF1ab/nsp4177E177EgaAgaG33B.1.6210.000266
ORF1ab/nsp4177E177EgaAgaG22AD.20.000438
ORF1ab/nsp4177E177EgaAgaG22AY.140.000176
ORF1ab/nsp4177E177EgaAgaG22AY.250.000012
ORF1ab/nsp4177E177EgaAgaG22AY.260.000057
ORF1ab/nsp4177E177EgaAgaG22AY.390.000049
ORF1ab/nsp4177E177EgaAgaG22AY.4.20.000043
ORF1ab/nsp4177E177EgaAgaG22B.1.1.4340.000697
ORF1ab/nsp4177E177EgaAgaG22B.1.1.5190.000079
ORF1ab/nsp4177E177EgaAgaG22B.1.1770.000026
ORF1ab/nsp4177E177EgaAgaG22B.1.177.330.003289
ORF1ab/nsp4177E177EgaAgaG22B.1.177.730.001133
ORF1ab/nsp4177E177EgaAgaG22B.1.5260.000047
ORF1ab/nsp4177E177EgaAgaG22B.1.5670.006667
ORF1ab/nsp4177E177EgaAgaG22B.1.5950.000522
ORF1ab/nsp4177E177EgaAgaG22B.310.007463
ORF1ab/nsp4177E177EgaAgaG22P.1.140.000096
ORF1ab/nsp4177E177EgaAgaG11A.23.10.000704
ORF1ab/nsp4177E177EgaAgaG11A.50.001923
ORF1ab/nsp4177E177EgaAgaG11AY.1080.001103
ORF1ab/nsp4177E177EgaAgaG11AY.1130.000142
ORF1ab/nsp4177E177EgaAgaG11AY.200.000039
ORF1ab/nsp4177E177EgaAgaG11AY.420.00004
ORF1ab/nsp4177E177EgaAgaG11AY.50.000021
ORF1ab/nsp4177E177EgaAgaG11AY.790.001211
ORF1ab/nsp4177E177EgaAgaG11B0.000128
ORF1ab/nsp4177E177EgaAgaG11B.1.1.1220.045455
ORF1ab/nsp4177E177EgaAgaG11B.1.1.2220.000204
ORF1ab/nsp4177E177EgaAgaG11B.1.1.3110.000358
ORF1ab/nsp4177E177EgaAgaG11B.1.1.3620.005618
ORF1ab/nsp4177E177EgaAgaG11B.1.1.4170.002703
ORF1ab/nsp4177E177EgaAgaG11B.1.1.4620.008621
ORF1ab/nsp4177E177EgaAgaG11B.1.177.170.000821
ORF1ab/nsp4177E177EgaAgaG11B.1.177.70.000165
ORF1ab/nsp4177E177EgaAgaG11B.1.1820.007246
ORF1ab/nsp4177E177EgaAgaG11B.1.214.30.007143
ORF1ab/nsp4177E177EgaAgaG11B.1.2340.000132
ORF1ab/nsp4177E177EgaAgaG11B.1.2430.00007
ORF1ab/nsp4177E177EgaAgaG11B.1.2580.000067
ORF1ab/nsp4177E177EgaAgaG11B.1.3670.000792
ORF1ab/nsp4177E177EgaAgaG11B.1.4200.010417
ORF1ab/nsp4177E177EgaAgaG11B.1.466.20.000391
ORF1ab/nsp4177E177EgaAgaG11B.1.4730.019231
ORF1ab/nsp4177E177EgaAgaG11B.1.5500.013699
ORF1ab/nsp4177E177EgaAgaG11B.1.5820.000491
ORF1ab/nsp4177E177EgaAgaG11B.1.6120.002653
ORF1ab/nsp4177E177EgaAgaG11B.1.6280.000352
ORF1ab/nsp4177E177EgaAgaG11B.1.6390.021739
ORF1ab/nsp4177E177EgaAgaG11C.360.000911
ORF1ab/nsp4177E177EgaAgaG11C.370.000116
ORF1ab/nsp4177E177EgaAgaG11D.20.000075
ORF1ab/nsp4177E177EgaAgaG11P.1.20.001156
ORF1ab/nsp4177E177EgaAgaG11P.20.000187
ORF1ab/nsp4177E177EgaAgaG11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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