CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = D217G

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4217D217GD2980GnonsyngAtgGt10055100530.9998019203-9205
ORF1ab/nsp4217D217GD2980GnonsyngATgGC1005510.0000994539203-9205
ORF1ab/nsp4217D217GD2980GnonsyngATgGA1005510.0000994539203-9205

Details of the mutation D217G within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4217D217GgAtgGt1005310055All0.001923
ORF1ab/nsp4217D217GgATgGA110055All0
ORF1ab/nsp4217D217GgATgGC110055All0
ORF1ab/nsp4217D217GgAtgGt68176817B.1.2340.899459
ORF1ab/nsp4217D217GgAtgGt642642B.1.214.20.384892
ORF1ab/nsp4217D217GgAtgGt593593A.270.981788
ORF1ab/nsp4217D217GgAtgGt438438B.10.004012
ORF1ab/nsp4217D217GgAtgGt325325AY.470.010109
ORF1ab/nsp4217D217GgAtgGt263263B.1.1.70.000235
ORF1ab/nsp4217D217GgAtgGt146146B.1.20.001286
ORF1ab/nsp4217D217GgAtgGt118118B.1.2580.007853
ORF1ab/nsp4217D217GgAtgGt6666B.1.2430.004593
ORF1ab/nsp4217D217GgAtgGt5656AY.1030.000348
ORF1ab/nsp4217D217GgAtgGt4040B.1.5960.003486
ORF1ab/nsp4217D217GgAtgGt3434B.1.10.000617
ORF1ab/nsp4217D217GgAtgGt3434B.1.2210.002415
ORF1ab/nsp4217D217GgAtgGt2424B.1.1770.000316
ORF1ab/nsp4217D217GgAtgGt1919A0.007353
ORF1ab/nsp4217D217GgAtgGt1818AY.430.00008
ORF1ab/nsp4217D217GgAtgGt1818B.1.617.20.000068
ORF1ab/nsp4217D217GgAtgGt1515B0.001917
ORF1ab/nsp4217D217GgAtgGt1414B.1.2060.011419
ORF1ab/nsp4217D217GgAtgGt1313AY.30.000129
ORF1ab/nsp4217D217GgAtgGt1212B.1.2100.025586
ORF1ab/nsp4217D217GgAtgGt1212B.1.5170.005124
ORF1ab/nsp4217D217GgAtgGt1111B.1.2140.040293
ORF1ab/nsp4217D217GgAtgGt1111B.1.4290.000259
ORF1ab/nsp4217D217GgAtgGt1111B.1.6390.23913
ORF1ab/nsp4217D217GgAtgGt1010B.1.1.100.011148
ORF1ab/nsp4217D217GgAtgGt99AY.40.000014
ORF1ab/nsp4217D217GgAtgGt99AY.440.000055
ORF1ab/nsp4217D217GgAtgGt99B.1.36.290.004656
ORF1ab/nsp4217D217GgAtgGt99P.10.000142
ORF1ab/nsp4217D217GgAtgGt88AY.290.000126
ORF1ab/nsp4217D217GgAtgGt88B.1.1.10.002614
ORF1ab/nsp4217D217GgAtgGt77AY.4.20.000152
ORF1ab/nsp4217D217GgAtgGt77B.1.5950.001827
ORF1ab/nsp4217D217GgAtgGt66B.1.1.500.004073
ORF1ab/nsp4217D217GgAtgGt66B.1.2400.001293
ORF1ab/nsp4217D217GgAtgGt66P.1.150.001394
ORF1ab/nsp4217D217GgAtgGt55B.1.177.730.002831
ORF1ab/nsp4217D217GgAtgGt55B.1.177.860.000917
ORF1ab/nsp4217D217GgAtgGt55B.1.3490.003574
ORF1ab/nsp4217D217GgAtgGt55B.1.4970.001574
ORF1ab/nsp4217D217GgAtgGt55B.1.5260.000118
ORF1ab/nsp4217D217GgAtgGt44AY.1020.000106
ORF1ab/nsp4217D217GgAtgGt44AY.250.000024
ORF1ab/nsp4217D217GgAtgGt44AY.390.000099
ORF1ab/nsp4217D217GgAtgGt44AY.740.000463
ORF1ab/nsp4217D217GgAtgGt44AY.98.10.000194
ORF1ab/nsp4217D217GgAtgGt44B.1.1.2220.000816
ORF1ab/nsp4217D217GgAtgGt44B.1.1600.000125
ORF1ab/nsp4217D217GgAtgGt44B.1.3960.002823
ORF1ab/nsp4217D217GgAtgGt44B.1.5690.057971
ORF1ab/nsp4217D217GgAtgGt44C.370.000464
ORF1ab/nsp4217D217GgAtgGt230.111111
ORF1ab/nsp4217D217GgATgGA130.055556
ORF1ab/nsp4217D217GgAtgGt33A.290.015957
ORF1ab/nsp4217D217GgAtgGt33AY.1190.000106
ORF1ab/nsp4217D217GgAtgGt33AY.860.00249
ORF1ab/nsp4217D217GgAtgGt33B.1.214.10.06
ORF1ab/nsp4217D217GgAtgGt33B.1.3110.000824
ORF1ab/nsp4217D217GgAtgGt33B.1.3690.000856
ORF1ab/nsp4217D217GgAtgGt33B.1.4270.000151
ORF1ab/nsp4217D217GgAtgGt33B.1.5800.012195
ORF1ab/nsp4217D217GgAtgGt33B.1.6210.000266
ORF1ab/nsp4217D217GgAtgGt33B.520.030303
ORF1ab/nsp4217D217GgAtgGt22A.20.001324
ORF1ab/nsp4217D217GgAtgGt22AY.320.001065
ORF1ab/nsp4217D217GgAtgGt22AY.340.000194
ORF1ab/nsp4217D217GgAtgGt22AY.620.000871
ORF1ab/nsp4217D217GgAtgGt22B.1.1.3980.006452
ORF1ab/nsp4217D217GgAtgGt22B.1.1.4220.090909
ORF1ab/nsp4217D217GgAtgGt22B.1.1.4320.002532
ORF1ab/nsp4217D217GgAtgGt22B.1.1.630.000772
ORF1ab/nsp4217D217GgAtgGt22B.1.1110.00235
ORF1ab/nsp4217D217GgAtgGt22B.1.177.60.001953
ORF1ab/nsp4217D217GgAtgGt22B.1.1790.007519
ORF1ab/nsp4217D217GgAtgGt22B.1.2840.026316
ORF1ab/nsp4217D217GgAtgGt22B.1.3510.000059
ORF1ab/nsp4217D217GgAtgGt22B.1.36.100.009569
ORF1ab/nsp4217D217GgAtgGt22B.1.362.20.009434
ORF1ab/nsp4217D217GgAtgGt22B.1.3670.001585
ORF1ab/nsp4217D217GgAtgGt22B.1.3750.001639
ORF1ab/nsp4217D217GgAtgGt22B.1.4030.006536
ORF1ab/nsp4217D217GgAtgGt22B.1.4170.057143
ORF1ab/nsp4217D217GgAtgGt22B.1.4590.008163
ORF1ab/nsp4217D217GgAtgGt22B.1.5670.006667
ORF1ab/nsp4217D217GgAtgGt22B.1.5770.001375
ORF1ab/nsp4217D217GgAtgGt22B.1.5810.018868
ORF1ab/nsp4217D217GgAtgGt22B.1.6370.000146
ORF1ab/nsp4217D217GgAtgGt22B.1.88.10.009615
ORF1ab/nsp4217D217GgAtgGt22P.1.140.000096
ORF1ab/nsp4217D217GgAtgGt22R.10.00018
ORF1ab/nsp4217D217GgAtgGt11A.10.000282
ORF1ab/nsp4217D217GgAtgGt11AW.10.003049
ORF1ab/nsp4217D217GgAtgGt11AY.1170.000085
ORF1ab/nsp4217D217GgAtgGt11AY.1200.000037
ORF1ab/nsp4217D217GgAtgGt11AY.180.010101
ORF1ab/nsp4217D217GgAtgGt11AY.230.00007
ORF1ab/nsp4217D217GgAtgGt11AY.4.2.10.000149
ORF1ab/nsp4217D217GgAtgGt11AY.50.000021
ORF1ab/nsp4217D217GgAtgGt11AY.590.00053
ORF1ab/nsp4217D217GgAtgGt11AY.750.000056
ORF1ab/nsp4217D217GgAtgGt11AY.770.001127
ORF1ab/nsp4217D217GgATgGC11AY.780.001541
ORF1ab/nsp4217D217GgAtgGt11AY.9.10.000084
ORF1ab/nsp4217D217GgAtgGt11B.1.1.2140.000055
ORF1ab/nsp4217D217GgAtgGt11B.1.1.2210.010101
ORF1ab/nsp4217D217GgAtgGt11B.1.1.2430.004082
ORF1ab/nsp4217D217GgAtgGt11B.1.1.250.000569
ORF1ab/nsp4217D217GgAtgGt11B.1.1.2650.003155
ORF1ab/nsp4217D217GgAtgGt11B.1.1.280.000311
ORF1ab/nsp4217D217GgAtgGt11B.1.1.2910.000742
ORF1ab/nsp4217D217GgAtgGt11B.1.1.3040.002809
ORF1ab/nsp4217D217GgAtgGt11B.1.1.3060.000438
ORF1ab/nsp4217D217GgAtgGt11B.1.1.3170.000412
ORF1ab/nsp4217D217GgAtgGt11B.1.1.3880.045455
ORF1ab/nsp4217D217GgAtgGt11B.1.1.390.00051
ORF1ab/nsp4217D217GgAtgGt11B.1.1.4340.000349
ORF1ab/nsp4217D217GgAtgGt11B.1.1.4400.011765
ORF1ab/nsp4217D217GgAtgGt11B.1.1.5180.006329
ORF1ab/nsp4217D217GgAtgGt11B.1.1.5250.005464
ORF1ab/nsp4217D217GgAtgGt11B.1.1130.015625
ORF1ab/nsp4217D217GgAtgGt11B.1.1570.002985
ORF1ab/nsp4217D217GgAtgGt11B.1.160.330.004425
ORF1ab/nsp4217D217GgAtgGt11B.1.177.440.000519
ORF1ab/nsp4217D217GgAtgGt11B.1.177.750.001041
ORF1ab/nsp4217D217GgAtgGt11B.1.214.30.007143
ORF1ab/nsp4217D217GgAtgGt11B.1.2320.000537
ORF1ab/nsp4217D217GgAtgGt11B.1.2390.001221
ORF1ab/nsp4217D217GgAtgGt11B.1.258.110.000396
ORF1ab/nsp4217D217GgAtgGt11B.1.2650.001271
ORF1ab/nsp4217D217GgAtgGt11B.1.2790.000514
ORF1ab/nsp4217D217GgAtgGt11B.1.3050.002151
ORF1ab/nsp4217D217GgAtgGt11B.1.3240.001605
ORF1ab/nsp4217D217GgAtgGt11B.1.360.000146
ORF1ab/nsp4217D217GgAtgGt11B.1.3710.001122
ORF1ab/nsp4217D217GgAtgGt11B.1.3820.008929
ORF1ab/nsp4217D217GgAtgGt11B.1.3950.007042
ORF1ab/nsp4217D217GgAtgGt11B.1.4260.001009
ORF1ab/nsp4217D217GgAtgGt11B.1.4360.001029
ORF1ab/nsp4217D217GgAtgGt11B.1.5270.003704
ORF1ab/nsp4217D217GgAtgGt11B.1.5660.019231
ORF1ab/nsp4217D217GgAtgGt11B.1.575.10.002439
ORF1ab/nsp4217D217GgAtgGt11B.1.5820.000491
ORF1ab/nsp4217D217GgAtgGt11B.1.5900.004545
ORF1ab/nsp4217D217GgAtgGt11B.1.6000.005848
ORF1ab/nsp4217D217GgAtgGt11B.1.6250.002353
ORF1ab/nsp4217D217GgAtgGt11B.1.780.008547
ORF1ab/nsp4217D217GgAtgGt11B.410.008
ORF1ab/nsp4217D217GgAtgGt11C.60.037037
ORF1ab/nsp4217D217GgAtgGt11Q.40.000455

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.