CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = A457V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4457A457VA3220VnonsyngCagTa664966450.9993989923-9925
ORF1ab/nsp4457A457VA3220VnonsyngCAgTG664930.0004511969923-9925
ORF1ab/nsp4457A457VA3220VnonsyngCAgTT664910.0001503999923-9925

Details of the mutation A457V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4457A457VgCagTa66456649All0.001271
ORF1ab/nsp4457A457VgCAgTG36649All0.000001
ORF1ab/nsp4457A457VgCAgTT16649All0
ORF1ab/nsp4457A457VgCagTa16671667AY.250.010027
ORF1ab/nsp4457A457VgCagTa597597B.1.1600.018619
ORF1ab/nsp4457A457VgCagTa515515B.1.1.70.000461
ORF1ab/nsp4457A457VgCagTa480480AY.40.000747
ORF1ab/nsp4457A457VgCagTa477477B.1.6270.963636
ORF1ab/nsp4457A457VgCagTa308308B.1.36.90.990354
ORF1ab/nsp4457A457VgCagTa294294B.1.6310.989899
ORF1ab/nsp4457A457VgCagTa285285B.1.20.00251
ORF1ab/nsp4457A457VgCagTa258258AY.30.002566
ORF1ab/nsp4457A457VgCagTa200202P.10.003151
ORF1ab/nsp4457A457VgCAgTG2202P.10.000032
ORF1ab/nsp4457A457VgCagTa164164AY.340.015902
ORF1ab/nsp4457A457VgCagTa144144AY.1030.000894
ORF1ab/nsp4457A457VgCagTa9797B.10.000888
ORF1ab/nsp4457A457VgCagTa9191B.1.10.001651
ORF1ab/nsp4457A457VgCagTa9191B.1.1770.001198
ORF1ab/nsp4457A457VgCagTa8888B.1.617.20.000331
ORF1ab/nsp4457A457VgCagTa6565AY.440.000396
ORF1ab/nsp4457A457VgCagTa3636B.1.5960.003137
ORF1ab/nsp4457A457VgCagTa3232B.1.360.004669
ORF1ab/nsp4457A457VgCagTa3232B.1.960.603774
ORF1ab/nsp4457A457VgCagTa3030AY.430.000133
ORF1ab/nsp4457A457VgCagTa3030B.1.1.1700.037406
ORF1ab/nsp4457A457VgCagTa2424AY.99.20.002212
ORF1ab/nsp4457A457VgCagTa2222AY.470.000684
ORF1ab/nsp4457A457VgCagTa2020AY.390.000494
ORF1ab/nsp4457A457VgCagTa1818B.1.2580.001198
ORF1ab/nsp4457A457VgCagTa1616AY.50.00033
ORF1ab/nsp4457A457VgCagTa1516B0.001917
ORF1ab/nsp4457A457VgCAgTT116B0.000128
ORF1ab/nsp4457A457VgCagTa1616B.1.2210.001137
ORF1ab/nsp4457A457VgCagTa1616B.1.4290.000376
ORF1ab/nsp4457A457VgCagTa1515B.1.5240.021097
ORF1ab/nsp4457A457VgCagTa1414AY.260.000396
ORF1ab/nsp4457A457VgCagTa1414B.1.5260.000329
ORF1ab/nsp4457A457VgCagTa1313AY.1000.000598
ORF1ab/nsp4457A457VgCagTa1313B.1.177.810.002461
ORF1ab/nsp4457A457VgCagTa1212B.1.2320.006448
ORF1ab/nsp4457A457VgCagTa1212B.1.6230.006438
ORF1ab/nsp4457A457VgCagTa1010B.1.1.700.003411
ORF1ab/nsp4457A457VgCagTa1010B.1.3510.000297
ORF1ab/nsp4457A457VgCagTa99AY.200.00035
ORF1ab/nsp4457A457VgCagTa99B.1.160.260.021792
ORF1ab/nsp4457A457VgCagTa88B.1.1.1570.007306
ORF1ab/nsp4457A457VgCagTa77A0.002709
ORF1ab/nsp4457A457VgCagTa77AY.1180.000439
ORF1ab/nsp4457A457VgCagTa77B.1.1.2220.001428
ORF1ab/nsp4457A457VgCagTa77B.1.1.5190.000278
ORF1ab/nsp4457A457VgCagTa66AY.4.20.00013
ORF1ab/nsp4457A457VgCagTa66B.1.2430.000418
ORF1ab/nsp4457A457VgCagTa66B.1.3810.046875
ORF1ab/nsp4457A457VgCagTa66Q.80.000989
ORF1ab/nsp4457A457VgCagTa55AY.20.001781
ORF1ab/nsp4457A457VgCagTa55AY.450.000608
ORF1ab/nsp4457A457VgCagTa55AY.46.30.004669
ORF1ab/nsp4457A457VgCagTa55AY.610.000524
ORF1ab/nsp4457A457VgCagTa55B.1.160.150.024752
ORF1ab/nsp4457A457VgCagTa55B.1.2340.00066
ORF1ab/nsp4457A457VgCagTa55B.1.3960.003529
ORF1ab/nsp4457A457VgCagTa55B.1.5760.004533
ORF1ab/nsp4457A457VgCagTa55B.1.6060.03012
ORF1ab/nsp4457A457VgCagTa44AY.1020.000106
ORF1ab/nsp4457A457VgCagTa44AY.1170.000338
ORF1ab/nsp4457A457VgCagTa44AY.690.000747
ORF1ab/nsp4457A457VgCagTa44B.1.1.2910.00297
ORF1ab/nsp4457A457VgCagTa44B.1.1.3650.022346
ORF1ab/nsp4457A457VgCagTa44B.1.1110.0047
ORF1ab/nsp4457A457VgCagTa44B.1.4220.003249
ORF1ab/nsp4457A457VgCagTa44B.1.4270.000202
ORF1ab/nsp4457A457VgCagTa44B.1.5820.001963
ORF1ab/nsp4457A457VgCagTa44P.40.015209
ORF1ab/nsp4457A457VgCagTa33AY.1190.000106
ORF1ab/nsp4457A457VgCagTa33AY.230.000209
ORF1ab/nsp4457A457VgCagTa33AY.270.000194
ORF1ab/nsp4457A457VgCagTa33AY.3.10.000256
ORF1ab/nsp4457A457VgCagTa33AY.330.0002
ORF1ab/nsp4457A457VgCagTa33AY.420.000121
ORF1ab/nsp4457A457VgCagTa33AY.460.000312
ORF1ab/nsp4457A457VgCagTa33AY.750.000168
ORF1ab/nsp4457A457VgCagTa33AY.830.005172
ORF1ab/nsp4457A457VgCagTa33B.1.1.10.00098
ORF1ab/nsp4457A457VgCagTa33B.1.1.3320.09375
ORF1ab/nsp4457A457VgCagTa33B.1.177.650.001996
ORF1ab/nsp4457A457VgCagTa33B.1.177.730.001699
ORF1ab/nsp4457A457VgCagTa33B.1.214.20.001799
ORF1ab/nsp4457A457VgCagTa33B.1.5170.001281
ORF1ab/nsp4457A457VgCagTa33B.1.6090.001438
ORF1ab/nsp4457A457VgCagTa33D.20.000225
ORF1ab/nsp4457A457VgCagTa33P.1.10.000953
ORF1ab/nsp4457A457VgCagTa23P.1.120.000968
ORF1ab/nsp4457A457VgCAgTG13P.1.120.000484
ORF1ab/nsp4457A457VgCagTa33P.1.140.000143
ORF1ab/nsp4457A457VgCagTa33P.1.150.000697
ORF1ab/nsp4457A457VgCagTa33P.1.20.003468
ORF1ab/nsp4457A457VgCagTa33Q.30.000435
ORF1ab/nsp4457A457VgCagTa33Q.40.001364
ORF1ab/nsp4457A457VgCagTa22AY.1200.000074
ORF1ab/nsp4457A457VgCagTa22AY.39.10.000079
ORF1ab/nsp4457A457VgCagTa22AY.46.50.000397
ORF1ab/nsp4457A457VgCagTa22AY.46.60.000144
ORF1ab/nsp4457A457VgCagTa22AY.590.001059
ORF1ab/nsp4457A457VgCagTa22AY.640.00119
ORF1ab/nsp4457A457VgCagTa22AY.730.001331
ORF1ab/nsp4457A457VgCagTa22AY.75.10.000361
ORF1ab/nsp4457A457VgCagTa22AY.9.20.000073
ORF1ab/nsp4457A457VgCagTa22B.1.1.2140.000111
ORF1ab/nsp4457A457VgCagTa22B.1.1.280.000622
ORF1ab/nsp4457A457VgCagTa22B.1.1.2840.000215
ORF1ab/nsp4457A457VgCagTa22B.1.1.3170.000823
ORF1ab/nsp4457A457VgCagTa22B.1.1.3290.007692
ORF1ab/nsp4457A457VgCagTa22B.1.1.370.000386
ORF1ab/nsp4457A457VgCagTa22B.1.1.3890.012121
ORF1ab/nsp4457A457VgCagTa22B.1.1.390.001019
ORF1ab/nsp4457A457VgCagTa22B.1.1.4160.00181
ORF1ab/nsp4457A457VgCagTa22B.1.1.4260.071429
ORF1ab/nsp4457A457VgCagTa22B.1.1.460.008734
ORF1ab/nsp4457A457VgCagTa22B.1.1.5230.003125
ORF1ab/nsp4457A457VgCagTa22B.1.160.90.014388
ORF1ab/nsp4457A457VgCagTa22B.1.177.120.000303
ORF1ab/nsp4457A457VgCagTa22B.1.177.560.001335
ORF1ab/nsp4457A457VgCagTa22B.1.177.580.002663
ORF1ab/nsp4457A457VgCagTa22B.1.177.600.000437
ORF1ab/nsp4457A457VgCagTa22B.1.177.70.00033
ORF1ab/nsp4457A457VgCagTa22B.1.2400.000431
ORF1ab/nsp4457A457VgCagTa22B.1.2650.002541
ORF1ab/nsp4457A457VgCagTa22B.1.2680.020833
ORF1ab/nsp4457A457VgCagTa22B.1.2800.014286
ORF1ab/nsp4457A457VgCagTa22B.1.3490.00143
ORF1ab/nsp4457A457VgCagTa22B.1.36.290.001035
ORF1ab/nsp4457A457VgCagTa22B.1.3750.001639
ORF1ab/nsp4457A457VgCagTa22B.1.3800.013245
ORF1ab/nsp4457A457VgCagTa22B.1.5560.015038
ORF1ab/nsp4457A457VgCagTa22B.1.5610.000794
ORF1ab/nsp4457A457VgCagTa22B.1.5640.000852
ORF1ab/nsp4457A457VgCagTa22B.1.5750.000607
ORF1ab/nsp4457A457VgCagTa22B.1.6210.000177
ORF1ab/nsp4457A457VgCagTa22B.1.9.50.011364
ORF1ab/nsp4457A457VgCagTa22B.400.000729
ORF1ab/nsp4457A457VgCagTa22C.350.001548
ORF1ab/nsp4457A457VgCagTa11A.20.000662
ORF1ab/nsp4457A457VgCagTa11A.2.5.20.001572
ORF1ab/nsp4457A457VgCagTa11AY.1050.000643
ORF1ab/nsp4457A457VgCagTa11AY.1210.000135
ORF1ab/nsp4457A457VgCagTa11AY.16.10.00047
ORF1ab/nsp4457A457VgCagTa11AY.23.10.000417
ORF1ab/nsp4457A457VgCagTa11AY.320.000532
ORF1ab/nsp4457A457VgCagTa11AY.350.000233
ORF1ab/nsp4457A457VgCagTa11AY.380.000499
ORF1ab/nsp4457A457VgCagTa11AY.4.30.000842
ORF1ab/nsp4457A457VgCagTa11AY.520.000814
ORF1ab/nsp4457A457VgCagTa11AY.550.000917
ORF1ab/nsp4457A457VgCagTa11AY.60.000041
ORF1ab/nsp4457A457VgCagTa11AY.620.000436
ORF1ab/nsp4457A457VgCagTa11AY.650.000533
ORF1ab/nsp4457A457VgCagTa11AY.680.000274
ORF1ab/nsp4457A457VgCagTa11AY.710.000475
ORF1ab/nsp4457A457VgCagTa11AY.740.000116
ORF1ab/nsp4457A457VgCagTa11AY.940.000443
ORF1ab/nsp4457A457VgCagTa11B.1.1.1530.001095
ORF1ab/nsp4457A457VgCagTa11B.1.1.1890.001513
ORF1ab/nsp4457A457VgCagTa11B.1.1.1920.002309
ORF1ab/nsp4457A457VgCagTa11B.1.1.2160.00089
ORF1ab/nsp4457A457VgCagTa11B.1.1.2400.004695
ORF1ab/nsp4457A457VgCagTa11B.1.1.2580.003257
ORF1ab/nsp4457A457VgCagTa11B.1.1.2630.001558
ORF1ab/nsp4457A457VgCagTa11B.1.1.2690.001353
ORF1ab/nsp4457A457VgCagTa11B.1.1.2740.005051
ORF1ab/nsp4457A457VgCagTa11B.1.1.3060.000438
ORF1ab/nsp4457A457VgCagTa11B.1.1.40.002976
ORF1ab/nsp4457A457VgCagTa11B.1.1.4340.000349
ORF1ab/nsp4457A457VgCagTa11B.1.1.4480.002033
ORF1ab/nsp4457A457VgCagTa11B.1.1.520.012195
ORF1ab/nsp4457A457VgCagTa11B.1.1080.005814
ORF1ab/nsp4457A457VgCagTa11B.1.160.80.001289
ORF1ab/nsp4457A457VgCagTa11B.1.1620.005025
ORF1ab/nsp4457A457VgCagTa11B.1.177.100.000878
ORF1ab/nsp4457A457VgCagTa11B.1.177.210.000076
ORF1ab/nsp4457A457VgCagTa11B.1.177.240.001295
ORF1ab/nsp4457A457VgCagTa11B.1.177.40.000211
ORF1ab/nsp4457A457VgCagTa11B.1.177.480.003125
ORF1ab/nsp4457A457VgCagTa11B.1.177.60.000977
ORF1ab/nsp4457A457VgCagTa11B.1.177.750.001041
ORF1ab/nsp4457A457VgCagTa11B.1.177.860.000183
ORF1ab/nsp4457A457VgCagTa11B.1.1890.004292
ORF1ab/nsp4457A457VgCagTa11B.1.2010.005682
ORF1ab/nsp4457A457VgCagTa11B.1.2060.000816
ORF1ab/nsp4457A457VgCagTa11B.1.2100.002132
ORF1ab/nsp4457A457VgCagTa11B.1.2390.001221
ORF1ab/nsp4457A457VgCagTa11B.1.2410.000812
ORF1ab/nsp4457A457VgCagTa11B.1.258.170.000104
ORF1ab/nsp4457A457VgCagTa11B.1.258.70.001912
ORF1ab/nsp4457A457VgCagTa11B.1.2600.003344
ORF1ab/nsp4457A457VgCagTa11B.1.3460.001311
ORF1ab/nsp4457A457VgCagTa11B.1.3560.001727
ORF1ab/nsp4457A457VgCagTa11B.1.36.260.002857
ORF1ab/nsp4457A457VgCagTa11B.1.3620.001541
ORF1ab/nsp4457A457VgCagTa11B.1.3710.001122
ORF1ab/nsp4457A457VgCagTa11B.1.4030.003268
ORF1ab/nsp4457A457VgCagTa11B.1.4360.001029
ORF1ab/nsp4457A457VgCagTa11B.1.4380.006536
ORF1ab/nsp4457A457VgCagTa11B.1.4530.003236
ORF1ab/nsp4457A457VgCagTa11B.1.466.10.007194
ORF1ab/nsp4457A457VgCagTa11B.1.4980.020408
ORF1ab/nsp4457A457VgCagTa11B.1.5200.021739
ORF1ab/nsp4457A457VgCagTa11B.1.5250.000113
ORF1ab/nsp4457A457VgCagTa11B.1.5510.00129
ORF1ab/nsp4457A457VgCagTa11B.1.5990.00365
ORF1ab/nsp4457A457VgCagTa11B.1.6200.000946
ORF1ab/nsp4457A457VgCagTa11B.1.6280.000352
ORF1ab/nsp4457A457VgCagTa11B.1.930.000934
ORF1ab/nsp4457A457VgCagTa11B.120.00641
ORF1ab/nsp4457A457VgCagTa11B.30.000831
ORF1ab/nsp4457A457VgCagTa11B.410.008
ORF1ab/nsp4457A457VgCagTa11B.550.00295
ORF1ab/nsp4457A457VgCagTa11B.610.005747
ORF1ab/nsp4457A457VgCagTa11C.330.058824
ORF1ab/nsp4457A457VgCagTa11C.360.000911
ORF1ab/nsp4457A457VgCagTa11C.36.30.000567
ORF1ab/nsp4457A457VgCagTa11P.1.100.000269
ORF1ab/nsp4457A457VgCagTa11P.1.170.000162
ORF1ab/nsp4457A457VgCagTa11P.1.70.000319
ORF1ab/nsp4457A457VgCagTa11P.20.000187
ORF1ab/nsp4457A457VgCagTa11Q.20.000613

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.