CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = A457T

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4457A457TA3220TnonsynGcaAca17017019923-9925

Details of the mutation A457T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4457A457TGcaAca170170All0.000033
ORF1ab/nsp4457A457TGcaAca3030AY.1030.000186
ORF1ab/nsp4457A457TGcaAca2222AY.40.000034
ORF1ab/nsp4457A457TGcaAca2020AY.440.000122
ORF1ab/nsp4457A457TGcaAca1212B.1.1.70.000011
ORF1ab/nsp4457A457TGcaAca1111B.1.617.20.000041
ORF1ab/nsp4457A457TGcaAca99AY.420.000362
ORF1ab/nsp4457A457TGcaAca88AY.430.000035
ORF1ab/nsp4457A457TGcaAca55A.2.5.20.007862
ORF1ab/nsp4457A457TGcaAca55AY.1190.000177
ORF1ab/nsp4457A457TGcaAca55B.1.20.000044
ORF1ab/nsp4457A457TGcaAca55B.400.001821
ORF1ab/nsp4457A457TGcaAca44AY.250.000024
ORF1ab/nsp4457A457TGcaAca44AY.390.000099
ORF1ab/nsp4457A457TGcaAca22AY.1000.000092
ORF1ab/nsp4457A457TGcaAca22AY.1020.000053
ORF1ab/nsp4457A457TGcaAca22AY.4.20.000043
ORF1ab/nsp4457A457TGcaAca22B.6.60.001778
ORF1ab/nsp4457A457TGcaAca22P.30.00319
ORF1ab/nsp4457A457TGcaAca11AY.1200.000037
ORF1ab/nsp4457A457TGcaAca11AY.200.000039
ORF1ab/nsp4457A457TGcaAca11AY.4.40.000409
ORF1ab/nsp4457A457TGcaAca11AY.46.20.000635
ORF1ab/nsp4457A457TGcaAca11AY.46.60.000072
ORF1ab/nsp4457A457TGcaAca11AY.550.000917
ORF1ab/nsp4457A457TGcaAca11AY.840.000437
ORF1ab/nsp4457A457TGcaAca11AY.9.10.000084
ORF1ab/nsp4457A457TGcaAca11AY.9.20.000037
ORF1ab/nsp4457A457TGcaAca11AY.920.000287
ORF1ab/nsp4457A457TGcaAca11AY.98.10.000048
ORF1ab/nsp4457A457TGcaAca11B.1.1.740.00431
ORF1ab/nsp4457A457TGcaAca11B.1.177.70.000165
ORF1ab/nsp4457A457TGcaAca11B.1.2580.000067
ORF1ab/nsp4457A457TGcaAca11B.1.3440.008197
ORF1ab/nsp4457A457TGcaAca11B.1.4290.000024
ORF1ab/nsp4457A457TGcaAca11B.1.60.017241
ORF1ab/nsp4457A457TGcaAca11B.1.6210.000089
ORF1ab/nsp4457A457TGcaAca11P.10.000016
ORF1ab/nsp4457A457TGcaAca11P.1.20.001156

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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