CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : Mut = A457G

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4457A457GA3220GnonsyngCagGa26250.9615389923-9925
ORF1ab/nsp4457A457GA3220GnonsyngCAgGT2610.03846159923-9925

Details of the mutation A457G within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4457A457GgCagGa2526All0.000005
ORF1ab/nsp4457A457GgCAgGT126All0
ORF1ab/nsp4457A457GgCagGa1212AY.40.000019
ORF1ab/nsp4457A457GgCagGa22AY.120.000632
ORF1ab/nsp4457A457GgCagGa22AY.390.000049
ORF1ab/nsp4457A457GgCagGa12B.1.5260.000024
ORF1ab/nsp4457A457GgCAgGT12B.1.5260.000024
ORF1ab/nsp4457A457GgCagGa11AY.330.000067
ORF1ab/nsp4457A457GgCagGa11AY.7.10.000113
ORF1ab/nsp4457A457GgCagGa11AY.75.10.00018
ORF1ab/nsp4457A457GgCagGa11B0.000128
ORF1ab/nsp4457A457GgCagGa11B.10.000009
ORF1ab/nsp4457A457GgCagGa11B.1.1.70.000001
ORF1ab/nsp4457A457GgCagGa11B.1.160.320.004292
ORF1ab/nsp4457A457GgCagGa11B.1.617.20.000004

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.