CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : CodonNum = 458

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4458M458IM3221InonsynatGatT10270101470.9880239926-9928
ORF1ab/nsp4458M458IM3221InonsynatGatA102701190.01158719926-9928
ORF1ab/nsp4458M458IM3221InonsynatGatC1027040.0003894849926-9928
ORF1ab/nsp4458M458delM3221deldelATG---13613619926-9928
ORF1ab/nsp4458M458VM3221VnonsynAtgGtg484819926-9928
ORF1ab/nsp4458M458LM3221LnonsynAtgCtg38330.8684219926-9928
ORF1ab/nsp4458M458LM3221LnonsynAtgTtg3850.1315799926-9928
ORF1ab/nsp4458M458TM3221TnonsynaTgaCg1080.89926-9928
ORF1ab/nsp4458M458TM3221TnonsynaTGaCC1010.19926-9928
ORF1ab/nsp4458M458TM3221TnonsynaTGaCT1010.19926-9928
ORF1ab/nsp4458M458RM3221RnonsynaTGaGA980.8888899926-9928
ORF1ab/nsp4458M458del1M3221del1delAtg-tg950.5555569926-9928
ORF1ab/nsp4458M458del1M3221del1delatGat-930.3333339926-9928
ORF1ab/nsp4458M458RM3221RnonsynaTgaGg910.1111119926-9928
ORF1ab/nsp4458M458del1M3221del1delaTga-g910.1111119926-9928
ORF1ab/nsp4458M458del2M3221del2delATg--g530.69926-9928
ORF1ab/nsp4458M458del2M3221del2delaTGa--520.49926-9928
ORF1ab/nsp4458M458KM3221KnonsynaTgaAg3319926-9928

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4458M458IatGatT1014710270All0.001941
ORF1ab/nsp4458M458IatGatA11910270All0.000023
ORF1ab/nsp4458M458IatGatC410270All0.000001
ORF1ab/nsp4458M458IatGatT75967636B.1.20.066886
ORF1ab/nsp4458M458IatGatA407636B.1.20.000352
ORF1ab/nsp4458M458IatGatT824832B.1.1.70.000738
ORF1ab/nsp4458M458IatGatA7832B.1.1.70.000006
ORF1ab/nsp4458M458IatGatC1832B.1.1.70.000001
ORF1ab/nsp4458M458IatGatT294294B.1.1.2320.533575
ORF1ab/nsp4458M458IatGatT217217B.1.5270.803704
ORF1ab/nsp4458M458IatGatT204204B.1.177.210.0156
ORF1ab/nsp4458M458IatGatT130139B.10.001191
ORF1ab/nsp4458M458IatGatA9139B.10.000082
ORF1ab/nsp4458M458delATG---136136All0.000026
ORF1ab/nsp4458M458IatGatT129130B.1.5960.011241
ORF1ab/nsp4458M458IatGatA1130B.1.5960.000087
ORF1ab/nsp4458M458IatGatT102113B.1.10.00185
ORF1ab/nsp4458M458IatGatA11113B.1.10.0002
ORF1ab/nsp4458M458IatGatT100100B.1.177.270.943396
ORF1ab/nsp4458M458IatGatT7070B.1.1.3170.028818
ORF1ab/nsp4458M458VAtgGtg4848All0.000009
ORF1ab/nsp4458M458IatGatT4242B.1.1.500.028513
ORF1ab/nsp4458M458delATG---4040B.1.1.70.000036
ORF1ab/nsp4458M458LAtgCtg3338All0.000006
ORF1ab/nsp4458M458LAtgTtg538All0.000001
ORF1ab/nsp4458M458IatGatT3032AY.40.000047
ORF1ab/nsp4458M458IatGatA132AY.40.000002
ORF1ab/nsp4458M458IatGatC132AY.40.000002
ORF1ab/nsp4458M458VAtgGtg2626AY.40.00004
ORF1ab/nsp4458M458IatGatT1726B.1.360.00248
ORF1ab/nsp4458M458IatGatA926B.1.360.001313
ORF1ab/nsp4458M458IatGatT2424B.1.1.2310.074303
ORF1ab/nsp4458M458IatGatT2323A.2.40.077441
ORF1ab/nsp4458M458IatGatT2323B.1.3980.068452
ORF1ab/nsp4458M458IatGatT2222AY.260.000623
ORF1ab/nsp4458M458IatGatA1321B.1.3510.000386
ORF1ab/nsp4458M458IatGatT821B.1.3510.000238
ORF1ab/nsp4458M458IatGatT1314B.1.1.4320.016456
ORF1ab/nsp4458M458IatGatA114B.1.1.4320.001266
ORF1ab/nsp4458M458IatGatT1313B.1.438.31
ORF1ab/nsp4458M458IatGatA612B.1.1770.000079
ORF1ab/nsp4458M458IatGatT512B.1.1770.000066
ORF1ab/nsp4458M458IatGatC112B.1.1770.000013
ORF1ab/nsp4458M458IatGatT1212B.1.617.20.000045
ORF1ab/nsp4458M458TaTgaCg810All0.000002
ORF1ab/nsp4458M458TaTGaCC110All0
ORF1ab/nsp4458M458TaTGaCT110All0
ORF1ab/nsp4458M458IatGatT1010B.1.1.3060.004384
ORF1ab/nsp4458M458LAtgCtg910B.1.20.000079
ORF1ab/nsp4458M458LAtgTtg110B.1.20.000009
ORF1ab/nsp4458M458IatGatT1010B.1.258.170.00104
ORF1ab/nsp4458M458IatGatT1010B.1.3990.019342
ORF1ab/nsp4458M458RaTGaGA89All0.000002
ORF1ab/nsp4458M458del1Atg-tg59All0.000001
ORF1ab/nsp4458M458del1atGat-39All0.000001
ORF1ab/nsp4458M458RaTgaGg19All0
ORF1ab/nsp4458M458del1aTga-g19All0
ORF1ab/nsp4458M458delATG---99B.10.000082
ORF1ab/nsp4458M458IatGatT99P.1.160.003367
ORF1ab/nsp4458M458IatGatT88AY.4.20.000174
ORF1ab/nsp4458M458IatGatT77AY.1190.000247
ORF1ab/nsp4458M458IatGatT77B.1.5610.002779
ORF1ab/nsp4458M458IatGatT66AY.1020.000159
ORF1ab/nsp4458M458delATG---66AY.40.000009
ORF1ab/nsp4458M458delATG---66AY.750.000336
ORF1ab/nsp4458M458IatGatT66B0.000767
ORF1ab/nsp4458M458LAtgCtg56B.1.1.70.000004
ORF1ab/nsp4458M458LAtgTtg16B.1.1.70.000001
ORF1ab/nsp4458M458IatGatT66B.1.3960.004234
ORF1ab/nsp4458M458IatGatT66B.1.4290.000141
ORF1ab/nsp4458M458IatGatT55A.50.009615
ORF1ab/nsp4458M458del2ATg--g35All0.000001
ORF1ab/nsp4458M458del2aTGa--25All0
ORF1ab/nsp4458M458delATG---55AY.4.50.000537
ORF1ab/nsp4458M458delATG---55B.1.1770.000066
ORF1ab/nsp4458M458LAtgCtg55B.1.177.110.008489
ORF1ab/nsp4458M458delATG---55B.1.617.20.000019
ORF1ab/nsp4458M458IatGatT45P.10.000063
ORF1ab/nsp4458M458IatGatA15P.10.000016
ORF1ab/nsp4458M458delATG---44AY.430.000018
ORF1ab/nsp4458M458IatGatT24AY.440.000012
ORF1ab/nsp4458M458IatGatA24AY.440.000012
ORF1ab/nsp4458M458delATG---44B.1.10.000073
ORF1ab/nsp4458M458IatGatT44B.1.1.2260.023256
ORF1ab/nsp4458M458IatGatT44B.1.1.2940.005063
ORF1ab/nsp4458M458IatGatT44B.1.1.3580.137931
ORF1ab/nsp4458M458IatGatT44B.1.1.3640.266667
ORF1ab/nsp4458M458RaTGaGA44B.1.1.70.000004
ORF1ab/nsp4458M458del2ATg--g24B.1.1.70.000002
ORF1ab/nsp4458M458del2aTGa--24B.1.1.70.000002
ORF1ab/nsp4458M458delATG---44B.1.177.40.000844
ORF1ab/nsp4458M458IatGatT34B.1.36.290.001552
ORF1ab/nsp4458M458IatGatA14B.1.36.290.000517
ORF1ab/nsp4458M458IatGatT44B.1.3690.001141
ORF1ab/nsp4458M458IatGatT44B.1.4670.16
ORF1ab/nsp4458M458IatGatA34B.1.6230.001609
ORF1ab/nsp4458M458IatGatT14B.1.6230.000536
ORF1ab/nsp4458M458delATG---44P.1.120.001936
ORF1ab/nsp4458M458IatGatT44P.20.000747
ORF1ab/nsp4458M458IatGatT33A0.001161
ORF1ab/nsp4458M458KaTgaAg33All0.000001
ORF1ab/nsp4458M458VAtgGtg33AY.120.000948
ORF1ab/nsp4458M458delATG---33AY.390.000074
ORF1ab/nsp4458M458IatGatT33B.1.1.5190.000119
ORF1ab/nsp4458M458del1Atg-tg33B.1.1.70.000003
ORF1ab/nsp4458M458IatGatT33B.1.177.810.000568
ORF1ab/nsp4458M458IatGatT33B.1.2340.000396
ORF1ab/nsp4458M458IatGatT33B.1.4270.000151
ORF1ab/nsp4458M458IatGatT23B.1.5670.006667
ORF1ab/nsp4458M458IatGatA13B.1.5670.003333
ORF1ab/nsp4458M458IatGatT33B.1.5950.000783
ORF1ab/nsp4458M458delATG---33P.10.000047
ORF1ab/nsp4458M458IatGatT22A.210.00554
ORF1ab/nsp4458M458IatGatT22AY.1030.000012
ORF1ab/nsp4458M458LAtgCtg22AY.260.000057
ORF1ab/nsp4458M458IatGatT12AY.30.00001
ORF1ab/nsp4458M458IatGatA12AY.30.00001
ORF1ab/nsp4458M458VAtgGtg22AY.390.000049
ORF1ab/nsp4458M458TaTgaCg22AY.40.000003
ORF1ab/nsp4458M458IatGatT22AY.470.000062
ORF1ab/nsp4458M458delATG---22AY.520.001629
ORF1ab/nsp4458M458IatGatT12AY.600.000938
ORF1ab/nsp4458M458IatGatA12AY.600.000938
ORF1ab/nsp4458M458LAtgCtg22AY.650.001066
ORF1ab/nsp4458M458IatGatT22AY.700.000417
ORF1ab/nsp4458M458IatGatT12AY.710.000475
ORF1ab/nsp4458M458IatGatA12AY.710.000475
ORF1ab/nsp4458M458LAtgTtg22B.10.000018
ORF1ab/nsp4458M458VAtgGtg22B.1.10.000036
ORF1ab/nsp4458M458TaTgaCg12B.1.10.000018
ORF1ab/nsp4458M458TaTGaCC12B.1.10.000018
ORF1ab/nsp4458M458IatGatT22B.1.1.1920.004619
ORF1ab/nsp4458M458IatGatT22B.1.1.2220.000408
ORF1ab/nsp4458M458IatGatT22B.1.1.3350.025974
ORF1ab/nsp4458M458delATG---22B.1.1.4090.005666
ORF1ab/nsp4458M458IatGatT22B.1.1.4640.002946
ORF1ab/nsp4458M458IatGatT22B.1.1040.00738
ORF1ab/nsp4458M458IatGatT22B.1.1600.000062
ORF1ab/nsp4458M458IatGatT22B.1.177.240.002591
ORF1ab/nsp4458M458delATG---22B.1.177.540.001213
ORF1ab/nsp4458M458LAtgCtg22B.1.177.570.000562
ORF1ab/nsp4458M458IatGatA12B.1.177.70.000165
ORF1ab/nsp4458M458IatGatT12B.1.177.70.000165
ORF1ab/nsp4458M458IatGatT22B.1.2210.000142
ORF1ab/nsp4458M458IatGatT22B.1.2230.005556
ORF1ab/nsp4458M458IatGatT22B.1.2430.000139
ORF1ab/nsp4458M458IatGatA22B.1.3110.000549
ORF1ab/nsp4458M458IatGatT22B.1.3290.001215
ORF1ab/nsp4458M458LAtgCtg22B.1.360.000292
ORF1ab/nsp4458M458IatGatT22B.1.5090.001732
ORF1ab/nsp4458M458IatGatT22B.1.5250.000226
ORF1ab/nsp4458M458IatGatT22B.1.5410.00885
ORF1ab/nsp4458M458del1atGat-22B.1.6270.00404
ORF1ab/nsp4458M458IatGatT22C.360.001821
ORF1ab/nsp4458M458IatGatT22Q.40.00091
ORF1ab/nsp4458M458IatGatT11A.170.090909
ORF1ab/nsp4458M458IatGatT11A.23.10.000704
ORF1ab/nsp4458M458IatGatT11AL.10.012987
ORF1ab/nsp4458M458IatGatT11AY.100.00053
ORF1ab/nsp4458M458delATG---11AY.1080.001103
ORF1ab/nsp4458M458delATG---11AY.1200.000037
ORF1ab/nsp4458M458IatGatA11AY.120.10.000321
ORF1ab/nsp4458M458IatGatT11AY.16.10.00047
ORF1ab/nsp4458M458delATG---11AY.190.00114
ORF1ab/nsp4458M458LAtgCtg11AY.200.000039
ORF1ab/nsp4458M458IatGatT11AY.200.000039
ORF1ab/nsp4458M458TaTGaCT11AY.250.000006
ORF1ab/nsp4458M458IatGatT11AY.250.000006
ORF1ab/nsp4458M458delATG---11AY.250.000006
ORF1ab/nsp4458M458delATG---11AY.260.000028
ORF1ab/nsp4458M458RaTGaGA11AY.30.00001
ORF1ab/nsp4458M458TaTgaCg11AY.30.00001
ORF1ab/nsp4458M458LAtgCtg11AY.300.000396
ORF1ab/nsp4458M458VAtgGtg11AY.330.000067
ORF1ab/nsp4458M458TaTgaCg11AY.330.000067
ORF1ab/nsp4458M458IatGatT11AY.350.000233
ORF1ab/nsp4458M458del2ATg--g11AY.40.000002
ORF1ab/nsp4458M458delATG---11AY.4.10.000737
ORF1ab/nsp4458M458delATG---11AY.4.2.10.000149
ORF1ab/nsp4458M458KaTgaAg11AY.440.000006
ORF1ab/nsp4458M458VAtgGtg11AY.460.000104
ORF1ab/nsp4458M458delATG---11AY.46.20.000635
ORF1ab/nsp4458M458IatGatT11AY.46.60.000072
ORF1ab/nsp4458M458delATG---11AY.50.000021
ORF1ab/nsp4458M458IatGatT11AY.50.000021
ORF1ab/nsp4458M458VAtgGtg11AY.520.000814
ORF1ab/nsp4458M458delATG---11AY.60.000041
ORF1ab/nsp4458M458IatGatT11AY.610.000105
ORF1ab/nsp4458M458IatGatT11AY.630.000387
ORF1ab/nsp4458M458delATG---11AY.670.000464
ORF1ab/nsp4458M458LAtgCtg11AY.680.000274
ORF1ab/nsp4458M458IatGatA11AY.690.000187
ORF1ab/nsp4458M458VAtgGtg11AY.7.10.000113
ORF1ab/nsp4458M458delATG---11AY.720.001361
ORF1ab/nsp4458M458IatGatT11AY.750.000056
ORF1ab/nsp4458M458RaTGaGA11AY.750.000056
ORF1ab/nsp4458M458VAtgGtg11AY.75.10.00018
ORF1ab/nsp4458M458LAtgCtg11AY.75.10.00018
ORF1ab/nsp4458M458VAtgGtg11AY.850.000427
ORF1ab/nsp4458M458delATG---11AY.9.20.000037
ORF1ab/nsp4458M458VAtgGtg11B0.000128
ORF1ab/nsp4458M458VAtgGtg11B.10.000009
ORF1ab/nsp4458M458KaTgaAg11B.10.000009
ORF1ab/nsp4458M458delATG---11B.1.1.1390.022727
ORF1ab/nsp4458M458IatGatT11B.1.1.1740.003378
ORF1ab/nsp4458M458IatGatT11B.1.1.2070.001182
ORF1ab/nsp4458M458IatGatT11B.1.1.2140.000055
ORF1ab/nsp4458M458delATG---11B.1.1.2360.006897
ORF1ab/nsp4458M458VAtgGtg11B.1.1.2630.001558
ORF1ab/nsp4458M458IatGatA11B.1.1.280.000311
ORF1ab/nsp4458M458IatGatT11B.1.1.2910.000742
ORF1ab/nsp4458M458del1atGat-11B.1.1.3060.000438
ORF1ab/nsp4458M458KaTgaAg11B.1.1.3110.000358
ORF1ab/nsp4458M458IatGatC11B.1.1.3190.017544
ORF1ab/nsp4458M458IatGatT11B.1.1.3260.001761
ORF1ab/nsp4458M458RaTGaGA11B.1.1.3480.000796
ORF1ab/nsp4458M458VAtgGtg11B.1.1.3480.000796
ORF1ab/nsp4458M458IatGatT11B.1.1.3510.002793
ORF1ab/nsp4458M458IatGatT11B.1.1.3540.004386
ORF1ab/nsp4458M458IatGatT11B.1.1.3650.005587
ORF1ab/nsp4458M458IatGatT11B.1.1.3690.000446
ORF1ab/nsp4458M458IatGatT11B.1.1.370.000193
ORF1ab/nsp4458M458LAtgTtg11B.1.1.390.00051
ORF1ab/nsp4458M458IatGatT11B.1.1.4420.018519
ORF1ab/nsp4458M458IatGatT11B.1.1.450.014085
ORF1ab/nsp4458M458delATG---11B.1.1.5280.004808
ORF1ab/nsp4458M458TaTgaCg11B.1.1.70.000001
ORF1ab/nsp4458M458VAtgGtg11B.1.1.70.000001
ORF1ab/nsp4458M458RaTgaGg11B.1.1.700.000341
ORF1ab/nsp4458M458IatGatA11B.1.1.80.003584
ORF1ab/nsp4458M458IatGatT11B.1.1.930.025641
ORF1ab/nsp4458M458IatGatT11B.1.1260.001276
ORF1ab/nsp4458M458IatGatT11B.1.1570.002985
ORF1ab/nsp4458M458delATG---11B.1.1600.000031
ORF1ab/nsp4458M458del1Atg-tg11B.1.1770.000013
ORF1ab/nsp4458M458delATG---11B.1.177.150.000631
ORF1ab/nsp4458M458delATG---11B.1.177.160.000664
ORF1ab/nsp4458M458del1Atg-tg11B.1.177.170.000821
ORF1ab/nsp4458M458delATG---11B.1.177.170.000821
ORF1ab/nsp4458M458LAtgCtg11B.1.177.180.00116
ORF1ab/nsp4458M458IatGatT11B.1.177.50.001242
ORF1ab/nsp4458M458delATG---11B.1.177.690.001484
ORF1ab/nsp4458M458IatGatT11B.1.177.730.000566
ORF1ab/nsp4458M458delATG---11B.1.177.760.002494
ORF1ab/nsp4458M458delATG---11B.1.177.810.000189
ORF1ab/nsp4458M458delATG---11B.1.177.870.000728
ORF1ab/nsp4458M458delATG---11B.1.1790.003759
ORF1ab/nsp4458M458IatGatT11B.1.1790.003759
ORF1ab/nsp4458M458IatGatT11B.1.1990.004132
ORF1ab/nsp4458M458VAtgGtg11B.1.2580.000067
ORF1ab/nsp4458M458IatGatT11B.1.2600.003344
ORF1ab/nsp4458M458IatGatT11B.1.3300.028571
ORF1ab/nsp4458M458IatGatT11B.1.3360.002439
ORF1ab/nsp4458M458IatGatT11B.1.3460.001311
ORF1ab/nsp4458M458delATG---11B.1.36.180.00042
ORF1ab/nsp4458M458IatGatT11B.1.4040.001302
ORF1ab/nsp4458M458VAtgGtg11B.1.4290.000024
ORF1ab/nsp4458M458delATG---11B.1.4290.000024
ORF1ab/nsp4458M458IatGatT11B.1.4380.006536
ORF1ab/nsp4458M458IatGatT11B.1.438.10.000107
ORF1ab/nsp4458M458delATG---11B.1.4560.003268
ORF1ab/nsp4458M458IatGatT11B.1.4620.007246
ORF1ab/nsp4458M458IatGatA11B.1.4970.000315
ORF1ab/nsp4458M458IatGatT11B.1.5230.002451
ORF1ab/nsp4458M458IatGatT11B.1.5240.001406
ORF1ab/nsp4458M458IatGatA11B.1.5300.007143
ORF1ab/nsp4458M458IatGatT11B.1.5600.00463
ORF1ab/nsp4458M458IatGatT11B.1.5640.000426
ORF1ab/nsp4458M458IatGatT11B.1.5760.000907
ORF1ab/nsp4458M458IatGatT11B.1.5800.004065
ORF1ab/nsp4458M458IatGatT11B.1.5820.000491
ORF1ab/nsp4458M458IatGatT11B.1.5900.004545
ORF1ab/nsp4458M458del1aTga-g11B.1.5960.000087
ORF1ab/nsp4458M458IatGatT11B.1.5970.00463
ORF1ab/nsp4458M458IatGatT11B.1.6090.000479
ORF1ab/nsp4458M458IatGatT11B.1.6120.002653
ORF1ab/nsp4458M458VAtgGtg11B.1.617.20.000004
ORF1ab/nsp4458M458IatGatT11B.1.6210.000089
ORF1ab/nsp4458M458IatGatT11B.1.6370.000073
ORF1ab/nsp4458M458TaTgaCg11B.550.00295
ORF1ab/nsp4458M458IatGatT11B.6.60.000889
ORF1ab/nsp4458M458TaTgaCg11C.36.30.000567
ORF1ab/nsp4458M458RaTGaGA11P.10.000016
ORF1ab/nsp4458M458LAtgCtg11P.10.000016
ORF1ab/nsp4458M458delATG---11P.1.10.10.00813
ORF1ab/nsp4458M458VAtgGtg11P.1.120.000484
ORF1ab/nsp4458M458IatGatT11P.1.150.000232
ORF1ab/nsp4458M458delATG---11P.1.150.000232
ORF1ab/nsp4458M458IatGatT11P.1.80.004785
ORF1ab/nsp4458M458delATG---11Q.10.000126
ORF1ab/nsp4458M458IatGatT11Q.10.000126
ORF1ab/nsp4458M458delATG---11Q.80.000165
ORF1ab/nsp4458M458IatGatA11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.