CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : CodonNum = 446 & Codon = Act

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4446A446TA3209TnonsynGctAct19419419890-9892

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4446A446TGctAct194194All0.000037
ORF1ab/nsp4446A446TGctAct3030B.1.1.70.000027
ORF1ab/nsp4446A446TGctAct2020B.1.2430.001392
ORF1ab/nsp4446A446TGctAct1818B.1.20.000158
ORF1ab/nsp4446A446TGctAct1111B.1.4270.000555
ORF1ab/nsp4446A446TGctAct1111B.1.4740.020913
ORF1ab/nsp4446A446TGctAct1010B.1.4290.000235
ORF1ab/nsp4446A446TGctAct1010B.1.617.20.000038
ORF1ab/nsp4446A446TGctAct88B.10.000073
ORF1ab/nsp4446A446TGctAct77B.1.1460.029661
ORF1ab/nsp4446A446TGctAct66AY.1000.000276
ORF1ab/nsp4446A446TGctAct55P.10.000079
ORF1ab/nsp4446A446TGctAct44AY.230.000279
ORF1ab/nsp4446A446TGctAct44AY.30.00004
ORF1ab/nsp4446A446TGctAct44AY.4.20.000087
ORF1ab/nsp4446A446TGctAct33AY.1020.00008
ORF1ab/nsp4446A446TGctAct33AY.250.000018
ORF1ab/nsp4446A446TGctAct33AY.40.000005
ORF1ab/nsp4446A446TGctAct33AY.440.000018
ORF1ab/nsp4446A446TGctAct22AY.46.40.000329
ORF1ab/nsp4446A446TGctAct22B.1.10.000036
ORF1ab/nsp4446A446TGctAct22B.1.3980.005952
ORF1ab/nsp4446A446TGctAct22B.1.5760.001813
ORF1ab/nsp4446A446TGctAct11AY.1030.000006
ORF1ab/nsp4446A446TGctAct11AY.1210.000135
ORF1ab/nsp4446A446TGctAct11AY.330.000067
ORF1ab/nsp4446A446TGctAct11AY.430.000004
ORF1ab/nsp4446A446TGctAct11AY.460.000104
ORF1ab/nsp4446A446TGctAct11AY.46.60.000072
ORF1ab/nsp4446A446TGctAct11B0.000128
ORF1ab/nsp4446A446TGctAct11B.1.1.2220.000204
ORF1ab/nsp4446A446TGctAct11B.1.1.280.000311
ORF1ab/nsp4446A446TGctAct11B.1.1.3060.000438
ORF1ab/nsp4446A446TGctAct11B.1.1.3350.012987
ORF1ab/nsp4446A446TGctAct11B.1.1.4370.010417
ORF1ab/nsp4446A446TGctAct11B.1.1.5190.00004
ORF1ab/nsp4446A446TGctAct11B.1.1400.018868
ORF1ab/nsp4446A446TGctAct11B.1.1770.000013
ORF1ab/nsp4446A446TGctAct11B.1.177.70.000165
ORF1ab/nsp4446A446TGctAct11B.1.2100.002132
ORF1ab/nsp4446A446TGctAct11B.1.3510.00003
ORF1ab/nsp4446A446TGctAct11B.1.360.000146
ORF1ab/nsp4446A446TGctAct11B.1.466.20.000391
ORF1ab/nsp4446A446TGctAct11B.1.5270.003704
ORF1ab/nsp4446A446TGctAct11B.1.5820.000491
ORF1ab/nsp4446A446TGctAct11B.1.6210.000089
ORF1ab/nsp4446A446TGctAct11P.20.000187
ORF1ab/nsp4446A446TGctAct11Q.10.000126
ORF1ab/nsp4446A446TGctAct11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.