CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : CodonNum = 438 & Codon = cCt

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4438L438PL3201PnonsyncTtcCt677976779719866-9868

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4438L438PcTtcCt6779767797All0.012967
ORF1ab/nsp4438L438PcTtcCt4227442274B.1.5260.99363
ORF1ab/nsp4438L438PcTtcCt1359513595B.1.6370.993423
ORF1ab/nsp4438L438PcTtcCt85528552C.370.992572
ORF1ab/nsp4438L438PcTtcCt11021102B.10.010094
ORF1ab/nsp4438L438PcTtcCt580580P.30.92504
ORF1ab/nsp4438L438PcTtcCt362362C.37.10.947644
ORF1ab/nsp4438L438PcTtcCt302302B.1.1.2140.016748
ORF1ab/nsp4438L438PcTtcCt260260P.40.988593
ORF1ab/nsp4438L438PcTtcCt127127B.1.10.002304
ORF1ab/nsp4438L438PcTtcCt9898C.1.20.417021
ORF1ab/nsp4438L438PcTtcCt5959B.1.1.70.000053
ORF1ab/nsp4438L438PcTtcCt3636B.1.6230.019313
ORF1ab/nsp4438L438PcTtcCt2929AY.40.000045
ORF1ab/nsp4438L438PcTtcCt2828B.1.177.730.015855
ORF1ab/nsp4438L438PcTtcCt2626C.390.490566
ORF1ab/nsp4438L438PcTtcCt2323B.1.177.70.003792
ORF1ab/nsp4438L438PcTtcCt1818B.1.20.000158
ORF1ab/nsp4438L438PcTtcCt1818B.1.214.20.010791
ORF1ab/nsp4438L438PcTtcCt1717C.36.3.10.046196
ORF1ab/nsp4438L438PcTtcCt1616P.10.000252
ORF1ab/nsp4438L438PcTtcCt1414B0.001789
ORF1ab/nsp4438L438PcTtcCt1212B.1.5750.003641
ORF1ab/nsp4438L438PcTtcCt1111AY.30.000109
ORF1ab/nsp4438L438PcTtcCt1010B.1.1.5070.086957
ORF1ab/nsp4438L438PcTtcCt1010P.1.150.002323
ORF1ab/nsp4438L438PcTtcCt99B.1.6380.473684
ORF1ab/nsp4438L438PcTtcCt88B.1.1.3480.006369
ORF1ab/nsp4438L438PcTtcCt88B.1.617.20.00003
ORF1ab/nsp4438L438PcTtcCt77B.1.1.3120.013384
ORF1ab/nsp4438L438PcTtcCt77B.1.6250.016471
ORF1ab/nsp4438L438PcTtcCt77B.1.6360.04698
ORF1ab/nsp4438L438PcTtcCt66B.1.1.10.00196
ORF1ab/nsp4438L438PcTtcCt66B.1.1.3720.004132
ORF1ab/nsp4438L438PcTtcCt55B.1.4270.000252
ORF1ab/nsp4438L438PcTtcCt44AY.420.000161
ORF1ab/nsp4438L438PcTtcCt44B.1.1.3160.0037
ORF1ab/nsp4438L438PcTtcCt44B.1.1.3170.001647
ORF1ab/nsp4438L438PcTtcCt44B.1.1110.0047
ORF1ab/nsp4438L438PcTtcCt44B.1.3510.000119
ORF1ab/nsp4438L438PcTtcCt44B.1.360.000584
ORF1ab/nsp4438L438PcTtcCt44B.1.4290.000094
ORF1ab/nsp4438L438PcTtcCt44B.1.6180.016129
ORF1ab/nsp4438L438PcTtcCt44P.1.120.001936
ORF1ab/nsp4438L438PcTtcCt33AY.440.000018
ORF1ab/nsp4438L438PcTtcCt33B.1.1.280.000934
ORF1ab/nsp4438L438PcTtcCt33B.1.1.5190.000119
ORF1ab/nsp4438L438PcTtcCt33B.1.1.5280.014423
ORF1ab/nsp4438L438PcTtcCt33B.1.243.10.066667
ORF1ab/nsp4438L438PcTtcCt33B.1.5230.007353
ORF1ab/nsp4438L438PcTtcCt33B.1.5300.021429
ORF1ab/nsp4438L438PcTtcCt33B.1.5440.018072
ORF1ab/nsp4438L438PcTtcCt33B.1.5610.001191
ORF1ab/nsp4438L438PcTtcCt33B.1.5960.000261
ORF1ab/nsp4438L438PcTtcCt33B.1.6090.001438
ORF1ab/nsp4438L438PcTtcCt33P.1.10.000953
ORF1ab/nsp4438L438PcTtcCt33P.1.140.000143
ORF1ab/nsp4438L438PcTtcCt33P.1.170.000485
ORF1ab/nsp4438L438PcTtcCt22AY.1000.000092
ORF1ab/nsp4438L438PcTtcCt22AY.1030.000012
ORF1ab/nsp4438L438PcTtcCt22AY.430.000009
ORF1ab/nsp4438L438PcTtcCt22AY.470.000062
ORF1ab/nsp4438L438PcTtcCt22B.1.1.2200.003717
ORF1ab/nsp4438L438PcTtcCt22B.1.1.5240.041667
ORF1ab/nsp4438L438PcTtcCt22B.1.1600.000062
ORF1ab/nsp4438L438PcTtcCt22B.1.2140.007326
ORF1ab/nsp4438L438PcTtcCt22B.1.2210.000142
ORF1ab/nsp4438L438PcTtcCt22B.1.258.170.000208
ORF1ab/nsp4438L438PcTtcCt22B.1.3110.000549
ORF1ab/nsp4438L438PcTtcCt22B.1.3360.004878
ORF1ab/nsp4438L438PcTtcCt22B.1.3750.001639
ORF1ab/nsp4438L438PcTtcCt22B.1.4130.008511
ORF1ab/nsp4438L438PcTtcCt22B.1.6210.000177
ORF1ab/nsp4438L438PcTtcCt11AY.1020.000027
ORF1ab/nsp4438L438PcTtcCt11AY.1070.000466
ORF1ab/nsp4438L438PcTtcCt11AY.1200.000037
ORF1ab/nsp4438L438PcTtcCt11AY.23.10.000417
ORF1ab/nsp4438L438PcTtcCt11AY.250.000006
ORF1ab/nsp4438L438PcTtcCt11AY.360.000148
ORF1ab/nsp4438L438PcTtcCt11AY.70.000196
ORF1ab/nsp4438L438PcTtcCt11B.1.1.2410.00207
ORF1ab/nsp4438L438PcTtcCt11B.1.1.2430.004082
ORF1ab/nsp4438L438PcTtcCt11B.1.1.2940.001266
ORF1ab/nsp4438L438PcTtcCt11B.1.1.3040.002809
ORF1ab/nsp4438L438PcTtcCt11B.1.1.340.013158
ORF1ab/nsp4438L438PcTtcCt11B.1.1.3890.006061
ORF1ab/nsp4438L438PcTtcCt11B.1.1.4020.011111
ORF1ab/nsp4438L438PcTtcCt11B.1.1.4320.001266
ORF1ab/nsp4438L438PcTtcCt11B.1.1570.002985
ORF1ab/nsp4438L438PcTtcCt11B.1.1700.00431
ORF1ab/nsp4438L438PcTtcCt11B.1.177.40.000211
ORF1ab/nsp4438L438PcTtcCt11B.1.2370.004975
ORF1ab/nsp4438L438PcTtcCt11B.1.2410.000812
ORF1ab/nsp4438L438PcTtcCt11B.1.2760.016949
ORF1ab/nsp4438L438PcTtcCt11B.1.2800.007143
ORF1ab/nsp4438L438PcTtcCt11B.1.3240.001605
ORF1ab/nsp4438L438PcTtcCt11B.1.3380.008621
ORF1ab/nsp4438L438PcTtcCt11B.1.3500.002933
ORF1ab/nsp4438L438PcTtcCt11B.1.3560.001727
ORF1ab/nsp4438L438PcTtcCt11B.1.3670.000792
ORF1ab/nsp4438L438PcTtcCt11B.1.3990.001934
ORF1ab/nsp4438L438PcTtcCt11B.1.4680.005714
ORF1ab/nsp4438L438PcTtcCt11B.1.4990.00105
ORF1ab/nsp4438L438PcTtcCt11B.1.5250.000113
ORF1ab/nsp4438L438PcTtcCt11B.1.5670.003333
ORF1ab/nsp4438L438PcTtcCt11B.1.5740.002151
ORF1ab/nsp4438L438PcTtcCt11B.1.5760.000907
ORF1ab/nsp4438L438PcTtcCt11B.1.5800.004065
ORF1ab/nsp4438L438PcTtcCt11B.1.5850.027778
ORF1ab/nsp4438L438PcTtcCt11B.1.5900.004545
ORF1ab/nsp4438L438PcTtcCt11B.1.617.10.000129
ORF1ab/nsp4438L438PcTtcCt11B.1.780.008547
ORF1ab/nsp4438L438PcTtcCt11B.60.00091
ORF1ab/nsp4438L438PcTtcCt11C.10.002392
ORF1ab/nsp4438L438PcTtcCt11C.350.000774
ORF1ab/nsp4438L438PcTtcCt11P.1.160.000374
ORF1ab/nsp4438L438PcTtcCt11P.1.20.001156
ORF1ab/nsp4438L438PcTtcCt11P.1.70.000319
ORF1ab/nsp4438L438PcTtcCt11P.20.000187
ORF1ab/nsp4438L438PcTtcCt11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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